WO2016019346A1 - Couvercle inférieur activant une lentille électronique - Google Patents

Couvercle inférieur activant une lentille électronique Download PDF

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Publication number
WO2016019346A1
WO2016019346A1 PCT/US2015/043307 US2015043307W WO2016019346A1 WO 2016019346 A1 WO2016019346 A1 WO 2016019346A1 US 2015043307 W US2015043307 W US 2015043307W WO 2016019346 A1 WO2016019346 A1 WO 2016019346A1
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WO
WIPO (PCT)
Prior art keywords
lens
contact lens
sensor
circuitry
accommodating contact
Prior art date
Application number
PCT/US2015/043307
Other languages
English (en)
Inventor
Steve WAITE
Amitava Gupta
Original Assignee
Onefocus Technology, Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Onefocus Technology, Llc filed Critical Onefocus Technology, Llc
Publication of WO2016019346A1 publication Critical patent/WO2016019346A1/fr

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Classifications

    • G—PHYSICS
    • G02—OPTICS
    • G02C—SPECTACLES; SUNGLASSES OR GOGGLES INSOFAR AS THEY HAVE THE SAME FEATURES AS SPECTACLES; CONTACT LENSES
    • G02C7/00—Optical parts
    • G02C7/02—Lenses; Lens systems ; Methods of designing lenses
    • G02C7/04—Contact lenses for the eyes
    • G—PHYSICS
    • G02—OPTICS
    • G02C—SPECTACLES; SUNGLASSES OR GOGGLES INSOFAR AS THEY HAVE THE SAME FEATURES AS SPECTACLES; CONTACT LENSES
    • G02C7/00—Optical parts
    • G02C7/02—Lenses; Lens systems ; Methods of designing lenses
    • G02C7/08—Auxiliary lenses; Arrangements for varying focal length
    • G02C7/081—Ophthalmic lenses with variable focal length
    • G02C7/083—Electrooptic lenses

Definitions

  • Prior contact lenses can be less than ideal in at least some respects. Although it has been proposed to use an accommodating lens to treat presbyopia with a contact lens, the prior contact lenses to treat presbyopia can be less than ideal in at least some instances.
  • the control of the focus of the prior accommodating contact lenses can be less than ideal, and may result in objects coming out of focus in at least some instances. Also, at least some of the prior methods focusing the lens can be less than ideal in at least some respects. Also, the prior accommodating contact lenses can be more expensive to produce than would be ideal.
  • the improved contact lenses will overcome at some of the deficiencies of the prior accommodating contact lenses and provide one or more of improved focus, improved user control, improved manufacturability, and combinations thereof.
  • an accommodating contact lens comprises a lower eyelid sensor to adjust the focus of the contact lens, which allows the user to control the focus of the contact lens by moving the lower eyelid over the lower eyelid sensor.
  • the accommodating contact lens comprises a variable optical power inner optical lens.
  • the variable optical power inner optical lens can be a central lens coupled to the sensor in order to increase optical power of the inner lens in response to the eyelid being placed over the sensor by the user.
  • the sensor can be coupled to the variable optical power optical lens with circuitry, and a power source can be coupled to the circuitry, in order to control the variable optical power lens in response to the eyelid.
  • an amount of optical power of the inner optical lens changes with an amount of coverage of the eyelid sensor.
  • the electro optical lens comprises a meniscus shape in order to fit between anterior and posterior surfaces of a contact lens.
  • the electro-optical lens comprises a liquid crystal material disposed between spaced apart electrodes to provide accommodative optical correction with decreased amounts of voltage.
  • the components of the electro-optical lens can be supported with an internal support of a contact lens module.
  • the module may comprise a meniscus shaped support comprising a convexly curved anterior surface and a concavely curved posterior surface.
  • the meniscus shaped electro-optical liquid crystal lens can be placed on the meniscus shape support.
  • the meniscus shaped support can facilitate manufacturing of the contact lens by providing a support for the components such as the variable power lens, the circuitry and the sensor when the soft contact lens material is placed on the lens.
  • the soft contact lens material comprises stiffness to add rigidity during the manufacturing process and comprises a soft material when hydrated for placement on the eye.
  • the eyelid sensor comprises an elongate sensor such as a piezo electric sensor configured to provide an increase in voltage to the sensor circuitry as the coverage of the eyelid over the sensor increases.
  • the sensor can be arranged along an elongate axis oriented toward the electro-optical lens in order to adjust optical power of the lens in response to the eyelid on the sensor.
  • the elongate sensor can be made with a width that is sufficiently narrow to inhibit visibility when worn and a length dimensioned such that the sensor can be located away from an optically useful portion of the contact lens comprising optical zone.
  • the accommodating contact lens comprises a self-supporting module encapsulated in a soft contact lens material.
  • the encapsulated self supporting module may comprise a support having the components of the soft contact lens placed thereon and coupled to the support such that the module support is capable of supporting the components without the soft contact lens material and prior to encapsulation in the soft contact lens material.
  • the components supported with the module comprise one or more of an electro-optical lens, an eyelid sensor, a power source, and circuitry to couple the sensor to the electro-optical lens.
  • the electro-optical lens can be configured in one or more of many ways and may comprise one or more of a liquid crystal lens or a diffractive lens.
  • the circuitry comprises an application specific integrated circuit (hereinafter "ASIC").
  • ASIC application specific integrated circuit
  • the ASIC may comprise one or more components such as high impedance detector circuitry coupled to the eyelid sensor, an amplifier to amplify the sensor signal, reference voltage circuitry to provide a reference voltage, logic circuitry coupled to the detector circuitry, and driver circuitry coupled to the logic circuitry and the electro-optical lens.
  • the detector circuitry may comprise asynchronous detector circuitry.
  • the reference voltage circuitry can be coupled to the logic circuitry.
  • the logic circuitry can be coupled to the reference voltage circuitry and the detector circuitry in order to determine when to drive the electro-optical lens into an accommodative condition providing additional optical power.
  • the logic circuitry can be configured in one or more of many ways and may comprise a comparator to compare the measured sensor voltage to the reference voltage, or a look up table.
  • the logic circuitry may comprise an array of logic gate, or a processor having a tangible medium comprising instructions of a computer program.
  • the electro-optical lens can be configured in one or more of many ways, and may comprise one or more of a liquid crystal, a diffractive optic, or an electro-wetting liquid lens.
  • the electro-optical lens comprises the liquid crystal.
  • the liquid crystal lens can be configured in one or more of many ways.
  • the liquid crystal lens comprises a first electrode on a first side of the lens and a second electrode on a second side of the lens with a liquid crystal material contained between the first electrode and the second electrode.
  • the electric field between the electrodes increases the index of refraction of the material.
  • the electro-optical lens may comprise may comprise one or more of a piano convex shape, a meniscus shape or a diffractive shape.
  • the index of refraction of the liquid crystal material substantially matches the index of refraction of the contact lens material when no index changing drive voltage is applied to the electrodes by the drive circuitry, such that the lens has no substantial optical power.
  • the index of refraction of the contact lens material can be within a range from about 1.35 to about 1.45, and the index of refraction of the liquid crystal material can be within this range.
  • the index of refraction of the liquid crystal material and the soft contact lens material are matched to within about +/- 0.04, for example +/-0.02.
  • the lens and drive circuitry can be configured to provide negative optical power to the lens without an index changing voltage to the electrodes and increase optical power with voltage to the electrodes from the drive circuitry.
  • the liquid crystal lens is configured with the liquid crystal material and dimensions in order to provide a change of at least about +2 Diopters with no more than about 12 Volts applied to the electrodes. In many embodiments, a voltage of about 9 Volts can provide an optical power of at least about +3 Diopters.
  • the electro-optical lens can be configured to provide a graded change in the optical path length of light travelling through the lens in order to provide optical power.
  • the graded change in optical path length can be provided with a varying thickness of the liquid crystal material or a varying voltage across the liquid crystal material, and combinations thereof.
  • the varying thickness of the liquid crystal material can be shaped with a profile such one or more of a curved lens shaped profile or a diffractive profile in order to provide the optical power.
  • the graded change in optical path length can be combined with the optical properties of the anterior and posterior surfaces of the contact lens in order to provide far vision correction when no substantial index changing voltage is applied to the electrodes by the drive circuitry.
  • the first electrode comprises a plurality of electrodes arranged to define an electrode array.
  • the electrode array may comprise an annular array of electrodes.
  • each of the plurality of electrodes is coupled to the drive circuitry in order to apply a different voltage to the plurality of the electrodes of the array, so as to provide a spherical change in optical path length of light traveling through the liquid crystal material.
  • the change in index of refraction of the liquid crystal material can be related to the voltage across the material
  • the varying voltage across the electrode can produce an index of refraction profile that varies across the liquid crystal material.
  • the electro-optical lens comprises a meniscus shaped electro-optical lens having a first convexly curved surface and a second opposing concavely curved surface.
  • the meniscus shaped liquid crystal material having electrodes on opposing outer surfaces can be provided in a contact lens having a thin profile.
  • the eyelid sensor can be configured in one or more of many ways. In many
  • the eyelid sensor comprise an elongate structure having a piezo electric material contained within a biocompatible material.
  • the eyelid sensor can be coupled to the detector circuitry with opposing ends of the sensor in order to measure voltage of the sensor in response to deflection of the sensor.
  • the piezo electric material is housed between two sheets of material sealed around the edges.
  • the eyelid sensor can comprise a length within a range from about 1 to 5 mm, a width within a range from about 20 um to about 200um, and a thickness within a range from about 10 um to about 100 um, for example from about 20 um to about 50 um. Force of the eyelid can induce bending of the piezo electric material that can be measured with the detector circuitry.
  • voltage of the sensor is related to the amount of bending provided by the eyelid. When the voltage of the sensor comprises a sufficient amount, the circuitry can apply voltage to the electrodes in order to increase the optical power of the electro-optical lens.
  • the circuitry is configured to provide a digital response to the eyelid on the sensor.
  • the circuitry can be configured to provide binary on or off state to the accommodative power of the electro-optical lens with the voltage to the electrodes in response to the eyelid on the sensor.
  • the circuitry can be configured to provide a digital response comprising three or more configurations such as a first configuration for far vision, a second configuration for intermediate vision, and a third configuration for far vision.
  • the far vision optical power can be within a range from about -0.5 to about + 0.5
  • the intermediate optical power range can be from about +1.0 to about +2
  • the near vision optical power range can be from about +2.5 to about +3.5D, for example.
  • the eyelid sensor may comprise a plurality of sensors arranged to provide a variable focus in response to an amount of coverage of the plurality of sensors with the eyelid.
  • Figure 1 A show a plan view of an accommodating contact lens comprising a lid sensor, in accordance with embodiments
  • Figure IB shows a side cross-sectional view of the accommodating contact lens as in Fig. 1A
  • Figure 2A shows a plan view of a lid sensor, in accordance with embodiments
  • Figure 2B shows a side cross-sectional view of the lid sensor as in Fig. 2A, in accordance with embodiments;
  • Figure 3 shows the circuitry of the accommodating contact lens, in accordance with embodiments
  • Figure 4A shows a plan view and Figure 4B shows a side cross-sectional view of an electro-optical lens, in accordance with embodiments;
  • Figure 5A shows a plan view and Figure 5B shows a side cross-sectional view of an electro-optical lens having an electrode array, in accordance with embodiments.
  • Figure 6A shows a plan view and Figure 6B shows a side cross-sectional view of a support module comprising circuitry components placed thereon prior to encapsulation in a soft contact lens module, in accordance with embodiments.
  • the embodiments as disclosed herein are particularly well suited for restoring accommodation with a contact lens and combination with one or more of many forms of vision correction.
  • Examples of contact lenses having components suitable for combination in accordance with embodiments disclosed herein include: PCT/US2014/013427; PCT/US2014/013859; and U.S. Appl. Ser. No. 61/919,691, the entire disclosures of which are incorporated herein by reference and suitable for combination in accordance with embodiments disclosed herein.
  • the electro-optical module as disclosed herein is well suited for combination with one or more of many forms of vision correction such as contact lenses, intraocular lenses and eyeglasses.
  • the embodiments as disclosed herein are well suited for combination with prior contact lenses and materials and can be combined in one or more of many ways.
  • soft contact lenses the embodiments as disclosed herein are well suited for combination with hybrid contact lenses such as lenses having a stiff or rigid inner material and as soft skirt, for example.
  • the "soft" contact lens material is described herein with reference to the material as placed on the eye, the material may comprise a stiff or rigid material prior to placement on the eye, for example when manufactured.
  • the eyelid sensor as described herein can be located at one or more of many locations, in order to detect one or more of the lower eyelid, the upper eyelid, and combinations thereof.
  • Figure 1A show a plan view of an accommodating contact lens 100 comprising a lid sensor 182, in accordance with embodiments.
  • the contact lens comprises a soft contact lens material 110 and a self-supporting accommodation module 150.
  • the module comprises a lid sensor 182, circuitry 180, power source 184, and electro-optical lens 160.
  • the lid sensor, circuitry, power source, and electro-optical lens are in communication through electrical connectors 186.
  • the lid sensor 182 may comprise a lower lid sensor, disposed on the outer skirt zone 164 of the contact lens.
  • the lower lid sensor 182 is coupled to circuitry 180, which is coupled to power source 184 and to an electro-optical lens 160 disposed on the inner optical zone 162 of the contact lens.
  • the inner optical zone 162 may comprise a central optical zone, for example.
  • lower lid sensor 182 is at least partially disposed within about 3mm from the bottom of the contact lens, where the lower lid is known to contact the lens during downward gaze in about 95% of the population.
  • the circuitry and power source are disposed away from the optical zone 162 and on the outer skirt zone of the contact lens, so as to avoid the inner optical zone of the contact lens.
  • the contact lens can be configured with the far vision refraction of the user, in order to provide quality far vision when the electro-optical lens provides no substantial optical power.
  • the circuitry is configured to change the optical power of the electro-optical lens in response to a position of the lower lid in relation to the lid sensor.
  • the electro-optical lens comprises a low optical power configuration for accommodating far vision of the user when the lid is away from sensor. As the lid moves toward the sensor and partially covers the sensor, the electro-optical lens comprises an intermediate optical power configuration. When the lid substantially covers the sensor, the electro-optical lens comprises a high optical power configuration for accommodating near vision of the user.
  • the amount of additional optical power of the electro-optical lens can be within a range from about +0.25 to about -0.25D, for example.
  • the amount of additional optical power of the electro-optical lens can be within a range from about +0.5 to about +2 D, for example.
  • the amount of additional optical power of the electro-optical lens can be within a range from about +2D to about +4D, for example.
  • Figure IB shows a side cross-sectional view of the accommodating contact lens 100 shown in Fig. 1A.
  • the contact lens comprises a soft contact lens material 110, which may comprise one or more of many known contact lens materials such as one or more of a hydrogel, soft acrylate, silicone hydrogel or silicone elastomer, for example.
  • Lid sensor 182 and electro- optical lens 160 are embedded within the soft contact lens material.
  • the curvatures of Figure IB are not shown to scale in order to illustrate the structures of an accommodating contact lens to correct myopia.
  • the upper anterior surface of the lens may comprise an optical zone 162 having a radius of curvature to correct the distance vision of the nearsighted patient.
  • the optical zone 162 can have an upper surface with a flatter curvature than the outer portion of the upper surface of the contact lens (not to scale).
  • the contact lens surfaces can correct the distance vision of the patient.
  • the index of refraction of the liquid crystal material of the accommodating contact lens approximates the index of refraction of the contact lens material.
  • the accommodating lens can have some optical power in the far vision configuration, and one or more surfaces of the contact lens can correct the optical power of the lens and refractive error of the eye in order to provide quality far vision.
  • Activation of the electro-optical lens 160 provides additional positive optical power such that the patient can view intermediate and near objects in focus.
  • FIG. 2A shows a plan view of a lid sensor 182, in accordance with embodiments.
  • the lid sensor comprises a piezoelectric sensor 190 and a covering 192.
  • the lower lid can move over the area of the sensor, resulting in a change in the amount of pressure exerted by the lid on the sensor.
  • the piezoelectric sensor can detect this change in pressure and convert it into electric energy, and this electric energy can be
  • the piezoelectric sensor may comprise one of many known piezoelectric materials, such as strontium titanate.
  • the refractive index of the piezoelectric material may not be match the refractive index of the soft contact lens material, and hence the piezoelectric sensor may be visible on the surface of the contact lens.
  • the width 196 of the piezoelectric sensor may be chosen such that the sensor can effectively detect movements of the eyelid relative to the contact lens, while remaining visually inconspicuous on the surface of the contact lens, about 100 um for example.
  • the length 194 of the piezoelectric sensor may be chosen such that the sensor fits within the diameter of the contact lens, for example in the range from about 1-10 mm. Preferably, the length is chosen such that the sensor is disposed outside of the inner optical zone of the contact lens, about 4 mm for example.
  • the piezoelectric sensor 190 is covered in a covering 192, which may comprise a thin, biocompatible material such as polyvinylidene difluoride (PVDF).
  • the covering may comprise a PVDF membrane with a thickness 193 of about 5 um, for example.
  • the refractive index of the covering material matches the refractive index of the soft contact lens material.
  • placing the biocompatible covering over the piezoelectric material may help improve the biocompatibility of the lid sensor.
  • the biocompatible covering can hermetically seal the piezo electric material.
  • Figure 2B shows a side cross-sectional view of the lid sensor 182 as in Fig. 2A, in accordance with embodiments.
  • the thickness 198 of the piezoelectric sensor 190 may be chosen such that the performance of the sensor is balanced against the dimensional limits of the contact lens, for example in the range from about 20 um to 50 um.
  • placing the covering 192 over the piezoelectric sensor comprises first depositing a piezoelectric material over a substrate comprising a first layer of the covering material, then depositing a second layer of the covering material over the piezoelectric material.
  • the edges 195 of the first and second layers of the covering material can be sealed together so as to completely envelop the piezoelectric material.
  • Figure 3 shows a circuitry 180 of the accommodating contact lens, in accordance with embodiments.
  • the circuitry comprises detector circuitry 200, logic circuitry 202, and drive circuitry 204.
  • the lid sensor 182 is in electric communication with the detector circuitry, which communicates with the logic circuitry, which communicates with the drive circuitry.
  • the drive circuitry is in electric communication with the electro-optical lens 160.
  • the power source 184 provides power to the circuitry, and may comprise one or more of many thin-film batteries, such as a solid electrolyte lithium ion battery, for example.
  • the sensor, circuitry, electro-optical lens, and power source are in electric communication through electrical connectors 186, which may comprise one or more of many materials known to conduct electric energy, such as gold, platinum, or titanium nitrite.
  • the lid sensor When the lid sensor detects a movement of the eyelid relative to the contact lens, it generates an electrical signal comprising energy as described herein.
  • the singal is passed to the detector circuitry as a voltage, which may comprise an application-specific integrated circuit capable of detecting the voltage passed from the lid sensor.
  • the detector circuitry may optionally comprise an asynchronous detection module, which can increase the signal-to-noise ratio of the input voltage signal by converting the signal into a periodic signal, amplifying the signal, and filtering out non-periodic noise components of the signal, as is well-known in the art.
  • Such an asynchronous detection module may detect a weak signal of a piezoelectric lid.
  • the voltage signal from the detector circuitry is passed to the logic circuitry, which may comprise a look-up table, a reference voltage, and a comparator.
  • the logic circuitry can compare the received voltage signal to a reference voltage to determine whether the signal constitutes a true signal, or a substantial movement of the user's eyelid relative to the contact lens. If the signal is determined to be a true signal, the logic circuitry communicates this information to the driver circuitry.
  • the driver circuitry may comprise a module that opens the circuit gate between the power source and the electro-optical cell, and a transistor, which can amplify the voltage of the power source.
  • the power source can only provide a limited voltage, for example about 3-3.5 V, and the electro-optical cell has a higher voltage in order to initiate accommodation, for example within a range from about 6-12 V.
  • the transistor may convert the direct current voltage to an alternating current voltage, superimpose two signals to double the voltage, then repeat the process to further amplify the voltage.
  • FIG 4A shows a plan view and Figure 4B shows a side cross-sectional view of an electro-optical lens 160, in accordance with embodiments.
  • the electro-optical lens is embedded in a contact lens, and configured to match the meniscus shape of the contact lens.
  • the electro- optical lens comprises a seed module 174, an electrode array 170, and a liquid crystal lens 172.
  • the seed module comprises a soft, biocompatible material such as PVDF, with a refractive index configured to match the index of the contact lens material.
  • the electrode array is etched onto the inner surfaces of the seed module.
  • the liquid crystal layer is deposited inside the seed module so as to be disposed between the two inner surfaces comprising the electrode arrays.
  • the seed module 174 can be placed on the support of the self supporting module prior to encapsulation as described herein.
  • the liquid crystal layer can be configured to match the far vision refraction of the user such that no substantial optical power is provided by the electro-optical lens.
  • the electrode array can apply an electrical potential across the liquid crystal layer, thereby changing the optical properties of the liquid crystal layer, including the refractive index. The change in the refractive index of the liquid crystal layer can change the optical power of the electro-optical lens to accommodate near or far vision of the user.
  • Figure 5A shows a plan view and Figure 5B shows a side cross-sectional view of an electro-optical lens 160 having an electrode array 170, in accordance with embodiments.
  • the electrode array comprises a plurality of discrete electrodes 176, such that the electro-optical lens provides optical power where higher voltage is applied at the center of the lens.
  • the steps may comprise increments, each increment within a range from about 0.1-2 V of an adjacent electrode.
  • the voltage applied at the outer zone of the lens is about 6 V, and the voltage applied at the inner or center zone of the lens is about 12 V, for example.
  • the liquid crystal layer has a minimum director force under which the liquid crystals do not respond, the minimum director force generally corresponding to about 6 V, for example. Accordingly, the voltage applied at the outermost zone of the lens is about 6 V in many embodiments, for example.
  • Figure 6A shows a plan view and Figure 6B shows a side cross-sectional view of a support module 150 comprising circuitry components placed thereon prior to encapsulation in a contact lens 100, in accordance with embodiments.
  • Figure 6B shows a side cross-sectional view of a support module 150 comprising circuitry components placed thereon prior to encapsulation in a contact lens 100, in accordance with embodiments.
  • the module is sized to engage the eyelids. At least a portion of the appropriately sized module can be placed in the mold and used to form the contact lens.
  • the module comprises an optically transmissive material comprising a plurality of anchor structures 152 that can be embedded in a soft contact lens material 110.
  • the optically transmissive material may be configured to have an index of refraction similar to the contact lens material, such that the anchor structures and the support are optically transparent.
  • the module may also comprise an accommodation module as described herein, having a lid sensor 182, circuitry 180, power source 184, electro-optical lens 160, and electrical connectors 186.
  • the self-supporting module may then be placed in a mold and encapsulated in the soft contact lens material to form the accommodating contact lens as described herein.

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  • Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Liquid Crystal (AREA)

Abstract

L'invention concerne une lentille de contact de réception, qui comprend un capteur de paupière inférieure pour régler le foyer de la lentille de contact, qui permet à l'utilisateur de commander le foyer de la lentille de contact en déplaçant la paupière inférieure sur le capteur de paupière inférieure. Dans de nombreux modes de réalisation, la lentille de contact de réception comprend une lentille optique interne à puissance optique variable couplée au capteur pour augmenter la puissance optique de la lentille interne en réponse à la paupière placée sur le capteur. Le capteur peut être couplé à la lentille à puissance optique variable avec des circuits, et une source d'alimentation peut être couplée aux circuits, au capteur et à la lentille interne à puissance optique variable.
PCT/US2015/043307 2014-07-31 2015-07-31 Couvercle inférieur activant une lentille électronique WO2016019346A1 (fr)

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US201462031245P 2014-07-31 2014-07-31
US62/031,245 2014-07-31

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US10302968B2 (en) 2013-01-28 2019-05-28 Onefocus Vision, Inc. Fluidic module for accommodating soft contact lens
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Cited By (19)

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US10754176B2 (en) 2013-01-28 2020-08-25 Onefocus Technology, Llc Accommodating soft contact lens
US11874531B2 (en) 2013-01-28 2024-01-16 Onefocus Technology, Llc Accommodating soft contact lens
US10302968B2 (en) 2013-01-28 2019-05-28 Onefocus Vision, Inc. Fluidic module for accommodating soft contact lens
US10338411B2 (en) 2013-01-28 2019-07-02 Onefocus Technology, Llc Accommodating soft contact lens
US10444543B2 (en) 2013-01-28 2019-10-15 Onefocus Vision, Inc. Control device responsive to lid fissure width
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US11143887B2 (en) 2013-12-20 2021-10-12 Onefocus Vision, Inc. Fluidic module for accommodating soft contact lens
US11774781B2 (en) 2013-12-20 2023-10-03 Onefocus Vision, Inc. Fluidic module for accommodating soft contact lens
US10761348B2 (en) 2015-11-11 2020-09-01 Onefocus Vision, Inc. Accommodating lens with cavity
US10942371B2 (en) 2015-11-11 2021-03-09 Onefocus Vision, Inc. Rotationally stabilized contact lens
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