WO2015183062A1

WO2015183062A1 - Multi-use ecological biocide formulations and method for the production thereof

Info

Publication number: WO2015183062A1
Application number: PCT/MA2014/000033
Authority: WO
Inventors: M Hamed El Morabit; Abdelilah Lafkih
Original assignee: M Hamed El Morabit; Abdelilah Lafkih
Priority date: 2014-05-28
Filing date: 2014-11-26
Publication date: 2015-12-03
Also published as: MA20150466A1; MA37082B1

Abstract

The invention relates to multi-use ecological biocide formulations which are non-herbicide and do not present any risk to humans, animals and the natural environment, consisting of substances of mineral and/or plant origin, which are easy to prepare. Said formulations are used to control insects, mites, fungi and bacteria. They are used to protect both grain stocks, and plants, livestock, and pets, as well as for workshops, warehouses and habitats.

Description

Multipurpose ecological biocidal formulations and method of preparation

summary

The present invention relates to ecological biocidal formulations, multi-purpose, non-herbicidal and safe for humans, animals and the natural environment, composed of substances of mineral and / or vegetable origin, easy to prepare. The formulations are for the control of insects, mites, fungi and bacteria. They are intended for the protection of grain stocks as for the preservation of plants, livestock and domestic animals, as well as for workshops, shops and housing.

Description

The increasing use of chemicals for the control of insects, fungi and bacteria has adverse effects on the environment due to the toxicity of the active ingredients. The use of diatomite or essential oils as ecological insecticides is known, it has been the subject of many patents on the preparation of products for the fight against insect pests and parasites. This is the case, for example, with patents or patent applications: US Pat. No. 3,917,014, US Pat. No. 3,215,541, US Pat. No. 5,328,821, US Pat. No. 5,328,828, US Pat. No. 4,129,517, US Pat. 6162825A, US 32354151A, US 5326560, PCT / EP / 2007/056562 P CT / F 2005/001267. The bibliography is very rich about the use of this type of ecological substances for the control of nuisances parasites. However, the combination of assemblages of diatoms, so-called diatomaceous earth, also known as diatomite, with plant substances such as aromatic and medicinal plants, as described below, constitutes the originality of the present invention. Also, the use of diatom assemblages of Moroccan origin, mixed with thyme, especially the Targistte thyme, from northern Morocco, proves to be very effective.

The subject of the invention is the formulation and the process for the production and implementation of non-herbicidal, biocidal preparations based on diatom assemblies, formed essentially of amorphous silica, known as organic silica or food-grade silica, derived inter alia , from the Rif region and / or the Middle Atlas region, mixed with other solid substances, of a mineral and / or vegetable nature, finely divided. The formulations, as developed, are chemically non-toxic and want to be effective in reducing the level of infestation of crops, plants, food, animals and more generally habitat ... etc. Beyond diatom assemblies, the mineral part may also be composed of carbonate or sodium bicarbonate and / or sodium tetraborate (borax) and / or plaster and / or lime and / or bentonite and / or pyrophyllite and or clays (Montmorillonite, marnes, ...) ■ The vegetable part is composed, essentially, of aromatic and medicinal plants, as vegetable substances such as thyme, especially the Targuiste thyme called locally "Zouy" or "azouy" », Rosemary, sagebrush, thymol, mint, peppermint, wormwood, chamomile, basil, eucalyptus, pyrethrum, .... The latter, whatever has no effect on being living in warm blood, it contains active ingredients, "pyrethrin and pyrethroids" which can be harmful to the environment; also, the use of the pyrethrum plant remains wisely for the protection of the natural environment. The vegetable substances are dried away from light and air currents, preferably at ambient temperatures, before grinding, alone or mixed, in proportions of the given formulations.

The biocidal formulations, according to the present invention, are effective against insects such as flies, aphids, aouta, worms, external larvae and internal parasites of animals, and also, against fungi and bacteria, ... . Among the advantages of the presence of certain plant substances in the formulations and to improve the efficacy of the biocide by the insecticidal, antifungal and antibacterial action, due to certain active principles present in particular in said plant substances, especially, aromatic plants and medicinal products (MAP) such as thyme, rosemary, lavandin, lavender, sagebrush, eucalyptus, thymol, mint, peppermint, wormwood, chamomile, basil, olive, rhubarb leaves, etc.

To attract certain insects, it is necessary to add an attractant to the formulation such as a food product, mainly sugars or sugar substitutes, preferably fruit sugars such as sugar cane and / or beet and / or the molasses of the two substances, taken separately or mixed together. Insects and pests attracted by the bait end up being eliminated because of the chemical action of the active ingredients of the formulation and / or by the physico-mechanical action, dehydration and / or laceration, diatom assemblies.

For the storage of biocidal preparations, it should be noted that the presence of bait tends to favor the development of certain parasites, especially in the absence of preservatives; this role is provided by certain active ingredients, such as sodium carbonate and / or certain plant substances among the components of the formulations, as proposed. The said formulations can be used in domestic and industrial conditions by direct application on the target (pests or sources of nuisance) or on the environment to be protected. For the conservation of grains, for example, and the control of Tribolium castaneum, lepidopteras (pyralidae) and certain coleopteras (Silvanidae, Tenebrionidae, Bostrichidae), one or more of the preparations presented in Tables 1 and 2 should be incorporated. in a proportion of the order of (500 to 3000) g / tonne of grains to be protected (wheat, corn, soya, flocculant or seed grains in general), preferably (1500 to 2300) g / tonne tonne. The moisture of the medium, ingredients and biocidal formulations shall be kept within reasonable limits so as not to exceed one percent (8%), preferably less than five percent (%). Good results are obtained, under such conditions, with homogeneous preparations based on finely ground ingredients, before or after mixing. The average size of the vegetable substances must be less than 500 microns, preferably less than 300 microns, preferably of the order of 100 microns. The average size of the mineral substances, in particular the diatom assemblies, must be less than 100 microns, preferably of the order of 50 microns;

In addition, diatom assemblies, in the form of dust, can cause irritation of the eyes and respiratory voices. To reduce this dust, during handling and / or application, it is advisable to incorporate poly glycols, such as polyethylene glycol (PEG400-PEG1000) or propylene glycol, into the biocidal formulations at a rate of at 40)%, preferably (15 to 25)%. Also, it is recommended to use goggles and dust masks during the application. Moreover, the residual products of these formulations, after use, do not present any environmental damage, they can be considered as fertilizers for the soil and antiseptics for the animal habitat. The so-called biocidal preparations are ecological and pose no danger to humans and animals.

In view of the method of preparation as described above, the powdered biocidal formulations shown in Table 1 prove to be effective for grain conservation and for other applications as insecticides and / or fungicides and / or bactericidal. Table 1

Example of biocidal preparations for the protection of

according to Embodiment 1 of the invention

* Especially the thyme of Targuiste (north of Morocco) locally called Zouy or Azouy

Also, and in accordance with a broad embodiment of mode 1 of the invention, there is provided an overall formulation and some typical formulations of biocides shown in Tables 2 and 3. It is obvious that examples of formulations can be multiplied without leaving the the scope of the invention as defined in the present description and the claims.

Table 2:

Global formulation of ecological biocide according to

Embodiment 1 of the invention

* Clay and crushed rocks: Montmorillonlte, marls, ..., bentonite, steveniste (ghassoule), pyrophyllite ... ** Aromatic and medicinal plants (thyme, thymol, lavandin, lavender, rosemary, sagebrush, eucalyptus, wormwood, chamomile, olive leaves, rhubarb leaves ...)

* Essentially sugars and derivatives = Fructose Table 3

Examples of typical biocidal formulations according to

Embodiment 1 of the invention

* (%) in relation to the total mass of the formulation

** Vegetable substances such as aromatic and medicinal plants such as thyme, mugwort, rosemary, wormwood, menthol, lavender, lavandin, chamomile, basil, eucalyptus, ..., taken separately or more mixed, preferably equally

In another embodiment 2 of the invention, the formulations can be used in the form of liquid suspensions in the amount of (5 to 50)%, preferably (20 to 24)%, dry matter in water, in ethyl alcohol or in the mixture of the two liquids, with a volume ratio of 10 to 90 (or vise versa). To improve the wettability and dispersion of the dry matter and the fluidity of the preparations, especially when they do not contain PEG, it is advisable to add additives such as dispersants, wetting agents, thickeners, etc. from (0.1 to 3)% of the total mass of the ready-to-use formulation. Said additives are widely reported in the documentation such as WIPO Patent Application WO / 2006/000671 A1, provided that they are not harmful to animal and plant life and the natural environment. This is the case, for example, with water-soluble polymers such as polyvinyl alcohols (PVA), corn starch, modified starches, polycarboxylates, their derivatives and / or copolymers, crosslinked polyvinylpyrrolidones, and polysaccharides. or their derivatives, calcium lignosulphonates, sodium carboxymethylcelluloses, alkali metal or ammonium salts such as triphosphates ... fatty acid esters, esters of fatty acids and of glycerol (stearate of glycerol) or esters of fatty acids and sugar (sorbitan stearate), as well as anionic surfactants (sodium or potassium alkyl phosphate).

Some ingredients and some additives have the characteristic of playing, also, the role of binders, such as clays, plaster, polyvinyl alcohol, carboxymethylcellulose, ...; which substances allow the biocidal preparation to attach, more or less slightly, to the target substrate capable of forming a thin layer on the treated substrate. By being wet, said biocidal layer can be swallowed by insects resistant to repulsive or dissuasive effects, possibly aided by the presence of an attractive bait. The insects succumb, afterwards, by laceration caused by sets of undigeable diatoms. On the other hand, after evaporation of the liquid phase, the diatom assemblies present in the biocide layer applied to the target substrate remain very active, turning into terrible desiccants. When insects come in contact with said diatom assemblages, they eventually succumb to dehydration.

In addition, some of the said additives are film-forming polymers, such as sodium carboxymethylcellulose, polyvinyl alcohol, modified corn starch, or the total or partial mixture of these substances. When formulations comprising such substances are applied by spraying droplets having a size (50 to 500) microns, preferably 150 microns, preferably 100 microns, they cause the formation of a film on the target substrate which trap insects, mites, bacteria, fungi, larvae ..., and, effectively contributes to the mechanical elimination or asphyxiation of such parasites. Furthermore, the diatom assemblies, by their absorbency and adsorbent, ensure a gradual release of water and volatile active substances, included in the composition, thus contributing to increase the active life of the biocidal formulations.

The biocidal formulations thus prepared can be marketed in the form of solid powders and the suspension can be carried out at the place of treatment, preferably just before application. In the case of presence of plant substances in the formulation, as described by the present invention, it is necessary to provide a limited passage of active ingredients, by maceration, in the liquid phase of the suspension. This does not disadvantage the effectiveness of the biocidal preparation.

In another embodiment 3 of the invention, instead of using plant substances as described above, biocidal formulations of the active ingredients are added to the mineral part. from said vegetable substances, in the form of extracts soluble in water (so-called water-soluble) or soluble in a mixture of water and alcohol (so-called hydro-alcoholic) thyme, especially Targuiste thyme locally called Zouy or azouy and / or rosemary and / or lavender and / or lavandin and / or sagebrush and / or eucalyptus and / or thymol and / or mint and / or peppermint and / or wormwood and / or chamomile and / or clove and / or cloves and / or olive leaves, and / or rhubarb and / or citrus leaves and / or garlic and / or onion and / or tobacco and / or cannabis (kif) and / or orange peel and / or bitter orange peel and / or geraniol and / or ginger ..., taken separately or mixed, partially or totally, depending on the desired insecticidal, fungicidal, bactericidal effect, as long as the mixture does not exhibit a phenomenon of toxic association. Said water-soluble and / or hydro-alcoholic extracts are obtained by decoction-maceration of natural plant substances, alone or mixed, at a rate of (500 to 1000) grams of dried vegetable substance (s), per liter of water, preferably demineralised. The mixture is boiled for (5 to 30) minutes and then left for cooling and maceration, protected from light, for at least 24 hours. 10% by volume of ethyl alcohol relative to the initial aqueous phase can be added to the mixture by homogenizing at regular intervals. The mixture is then filtered and water (or ethyl alcohol) is added to the resulting solution (filtrate) to the initial level of the liquid (11 liters for (500 to 1000) grams of plant substance). To the solution thus obtained, ie solution (A), the water-soluble active ingredients and the water-soluble additives are added in accordance with the proportions of the biocidal formulation. The solution thus prepared, ie the solution (B), is intimately mixed by mechanical stirring with the non-soluble mineral part of the biocidal formulation; the suspension (C) is thus obtained. For the application, said suspension (C) is diluted 500 times, or preferably 100 times or preferably 50 times or preferably 25 times or preferably 10 times.

Otherwise, the vegetable substances may be macerated cold and protected from light in oils, such as soybean oil or olive oil, for at least 48 hours, preferably for one week. After filtration, it is possible to use the same protocol used for maceration in water and / or in ethyl alcohol; the amount of water must be sufficient to dissolve the water soluble mineral ingredients of the formulation. On the other hand, the additives to be chosen to improve the fluidity of the preparation, according to the composition of the formulation, must be non-toxic and suitable for the formation of oil emulsion in water. . The final product is a suspension of the insoluble mineral solid in an oil-in-water emulsion. By respecting the method of preparation 3, as described above, the two biocidal formulations, shown in Table 4 expressed in (%) relative to the total mass of the preparation, prove to be effective as insecticides. , fungicides and bactericides, for the protection of plants of fruit vegetables and domestic and / or farm animals.

Table 4

Example of biocidal preparations for applications

according to Embodiment 3 of the invention

* Composition in (%) relative to the total mass of the biocidal formulation by considering the masses of the ingredients taken in the solid state and the mass of extract (s) soluble (s) in the liquid state

Table 5

Example of overall formulation according to

Embodiment 3 of the invention

** Sets of diatoms, clays, pyrophyllite, plaster, ...

*** Vegetable extracts according to the description: thyme, thymol, lavender, lavender, mint, peppermint, rosemary, sagebrush, eucalyptus, basil, wormwood, rhubarb leaves, olive leaves, etc., **** Carbonate or bicarbonate of soda and / or borax

***** Water-soluble polymers: PEG, CMC, PVA, .... Water-soluble mineral dispersants: tri poly sodium, potassium or ammonium phosphate ... Table 6

Examples of typical formulations according to Embodiment 3 of the invention

* Composition in {%) relative to the total mass of the biocidal formulation ** Sets of diatoms, clays, pyrophyllite, plaster, ...

Claims

claims

1. Multi-use, improved-efficacy ecological biocidal powder formulations based on inorganic or organic, non-herbicidal active substances, consisting essentially of diatom assemblages and natural non-toxic vegetable substances for the control of insects, bacteria and fungi, recommended for the conservation of wheat grains and similar products, for the protection of farm animals and plants, and for the protection of habitat, shops and workshops;

2. Formulations according to claim 1, characterized in that the active ingredients present in plant substances such as thyme especially Targuiste thyme locally called Zouy or azouy and / or rosemary and / or lavender and / or sagebrush and / or basil and / or eucalyptus and / or thymol and / or mint and / or wormwood and / or chamomile and / or peppermint, .... act naturally and locally, synergistically with the other ingredients of the formulations, in particular the diatom assemblies, and improve the fungicidal and bactericidal insecticidal action of said formulation, without adverse effects harmful to humans, animals and the natural environment.

3. Formulations according to claims 1 and 2, characterized in that the ingredients of the preparation are dried, preferably in the absence of air and at temperatures below 55 ° C for the vegetable substances. The moisture of the medium and ingredients should be less than 8 percent (%), preferably less than 5 percent (%). Said ingredients are then mixed and finely ground. The average size of the vegetable substances must be less than 500 microns, preferably less than 400 microns, preferably of the order of 100 microns. The average size of the mineral substances, in particular the diatom assemblies, must be less than 100 microns, preferably of the order of 50 microns;

4. Formulations according to claims 1, 2 and 3, characterized in that they consist essentially of (0 to 90)% of diatom assemblies, preferably 43% of the total mass of the preparation; carbonate or baking soda and / or borax at (0 to 30)%, preferably 17%; dry vegetable substances essentially comprising Thyme, especially Targuiste thyme locally called Zouy or azouy, and / or menthol and / or thymol and / or lavender and / or lavandin, and / or wormwood and and / or eucalyptus and / or rosemary and / or mugwort and / or chamomile and / or basil, peppermint, etc., at the rate of (10 to 90)%, preferably 40% ;

5. Formulations according to claims 1, 2, 3 and 4, characterized in that the preparation can be suspended in liquid in water and / or in ethyl alcohol at a rate of (5 to 40)% of material solid. In order to improve the fluidity of the preparations, the wettability and the dispersion of the dry matter, especially when the powder composition does not contain compounds with a similar effect such as polyethylene glycol, it is necessary to add ecological additives such as dispersants and / or wetting agents and / or thickeners, ..., at the rate of (0.1 to 3)% of the total mass of the ready-to-use formulation;

Formulations according to claims 1, 2, 3, 4 and 5, characterized in that they are applicable in powder form, by direct spraying on the target substrate, or as a suspension in water and / or in ethyl alcohol at a level of (5 to 40)% solids;

7. Formulations according to claims 1 and 2, characterized in that the natural vegetable substances are introduced in the form of liquid extracts obtained by decoction-maceration in water and / or in the alcohol of said vegetable substances such as thyme and and / or rosemary and / or lavandin and / or lavender and / or mugwort and / or eucalyptus and / or thymol and / or mint and / or peppermint and / or wormwood and / or menthol and / or chamomile and / or clove and / or cloves and / or citrus and / or garlic and / or onion and / or tobacco and / or cannabis (kif) and / or orange peel and / or bitter orange peel and / or geraniol and / or ginger and / or olive leaves and / or rhubarb leaves ..., taken separately or mixed, partially or totally, depending on the desired insecticidal, fungicidal, bactericidal effect, as long as the mixture does not exhibit a phenomenon of toxic association;

Formulations according to claims 1, 2 and 7, characterized in that they consist of diatom assemblies in the proportion of (20 to 90)% of the total mass of the ready-to-use biocidal preparation, preferably (39 to 50)%; water-soluble and / or hydroalcoholic extracts of plants in a proportion of (10 to 90)%, preferably (25 to 40)%; sodium bicarbonate at (0 to 30)%, preferably (11 to 14)%; sugars or sugar compounds, preferably fruit sugars as bait in the amount of (0 to 20)%, in addition to water-soluble and chemically non-toxic additions, to improve the fluidity of the preparation and the adhesion to the substrate target, at the rate of (0 to 25)%;

9. Formulations according to claims 1, 2, 7 and 8, characterized in that the water-soluble plant extracts are obtained by decoction-maceration of natural plant substances, taken separately or mixed, at a rate of (500 to 1000) grams of dry matter. per liter of water, preferably demineralised. The mixture is boiled for (5 to 30) minutes and then left for cooling and maceration, preferably in the absence of light, for at least 24 hours. Where appropriate, up to 10% by volume ethyl alcohol may be added to the initial aqueous phase by homogenizing at regular intervals. The mixture is then filtered and to the solution obtained (filtrate) water or ethyl alcohol is added up to the initial level of the liquid (11 liters per 500 to 1000 grams of dry vegetable substances), ie the solution (A). ), in which the active ingredients (water-soluble and / or hydro-alcoholic) and the additives (water-soluble and / or hydro-alcoholic) are dissolved in accordance with the proportions of the biocidal formulation. To the solution obtained, ie the solution (B), the non-soluble mineral part of the biocidal formulation is added. The mixture is intimately homogenized by mechanical stirring to thereby obtain the suspension (C). For the application, said suspension (C) is diluted 500 times or preferably 100 times or preferably 50 times or preferably 25 times or preferably 10 times;

10. Formulations according to claims 1, 5, 7, 8, and 9, characterized in that the adsorbent and / or absorbent power of diatom assemblies ensures a gradual release of water and volatile active ingredients thus making it possible to improve the shelf life of the activity of biocidal preparations.