WO2015182125A1 - Dispositif de mesure et procédé de mesure - Google Patents

Dispositif de mesure et procédé de mesure Download PDF

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Publication number
WO2015182125A1
WO2015182125A1 PCT/JP2015/002655 JP2015002655W WO2015182125A1 WO 2015182125 A1 WO2015182125 A1 WO 2015182125A1 JP 2015002655 W JP2015002655 W JP 2015002655W WO 2015182125 A1 WO2015182125 A1 WO 2015182125A1
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WO
WIPO (PCT)
Prior art keywords
unit
measurement
laser light
pressure
biological information
Prior art date
Application number
PCT/JP2015/002655
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English (en)
Japanese (ja)
Inventor
正太郎 杉田
孝昭 和田
Original Assignee
京セラ株式会社
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 京セラ株式会社 filed Critical 京セラ株式会社
Publication of WO2015182125A1 publication Critical patent/WO2015182125A1/fr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/024—Detecting, measuring or recording pulse rate or heart rate
    • A61B5/0245—Detecting, measuring or recording pulse rate or heart rate by using sensing means generating electric signals, i.e. ECG signals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/026—Measuring blood flow

Definitions

  • the present invention relates to a measuring apparatus and a measuring method.
  • a measuring device that acquires biological output information from a test site such as a fingertip of a subject (user) and measures the biological information is known.
  • a blood flow measuring device that measures blood flow as biological information irradiates a fingertip with a laser beam and measures blood flow based on scattered light from blood flow of capillaries at the fingertip (see, for example, Patent Document 1). ).
  • the laser beam has high directivity and has high energy because the wavelength and phase are uniform. Therefore, a measuring apparatus that measures biological information by irradiating laser light needs to emit laser light when the laser emission port is covered, from the viewpoint of safety.
  • An object of the present invention made in view of such circumstances is to provide a measuring apparatus and a measuring method capable of improving safety.
  • a measuring apparatus provides: A measurement device that measures biological information by bringing a test site into contact with a measurement unit, A pressure detection unit for detecting pressure acting on the measurement unit; A laser light source for emitting laser light; A light receiving unit that receives the scattered light of the laser beam from the test site; A biological information generation unit that generates the biological information based on the output of the light receiving unit; A control unit, The control unit emits the laser light from the laser light source when the pressure detected by the pressure detection unit is within a predetermined pressure range.
  • the measuring device is A measurement device that measures biological information by bringing a test site into contact with a measurement unit, A pressure detection unit for detecting pressure acting on the measurement unit; A temperature detection unit for detecting the temperature of the measurement unit; A laser light source for emitting laser light; A light receiving unit that receives the scattered light of the laser beam from the test site; A biological information generation unit that generates the biological information based on the output of the light receiving unit; A control unit, The controller is The laser light is emitted from the laser light source when the pressure detected by the pressure detector is within a predetermined pressure range and the temperature detected by the temperature detector is within a predetermined temperature range. .
  • the predetermined temperature range may be determined based on a temperature around the measurement unit.
  • the control unit may stop the emission of the laser beam from the laser light source when the pressure detected by the pressure detection unit is not within the predetermined pressure range.
  • the biological information may include information related to blood flow.
  • the present invention can be realized as a method substantially corresponding to the measurement apparatus described above, and these are also included in the scope of the present invention.
  • the measuring method is: It is a measurement method by a measurement device that measures biological information by bringing a test site into contact with a measurement unit, A pressure detecting step for detecting a pressure acting on the measuring unit; When the detected pressure is within a predetermined pressure range, an irradiation step of irradiating a laser beam to the test site that is in contact with the measurement unit; A light receiving step for receiving the scattered light of the laser light at the test site; A biological information generation step of generating the biological information based on the scattered light.
  • FIG. 1 It is a functional block diagram which shows schematic structure of the measuring apparatus which concerns on one embodiment of this invention. It is a figure which shows an example of the use condition of a measuring apparatus. It is a flowchart which shows an example of the emission control of the laser beam in a control part. It is a figure which shows an example of the mobile telephone carrying the measuring apparatus of FIG.
  • FIG. 1 is a functional block diagram showing a schematic configuration of a measuring apparatus according to an embodiment of the present invention.
  • the measurement apparatus 10 includes a pressure detection unit 11, a temperature detection unit 12, a biological sensor 13, a control unit 14, a storage unit 15, a measurement unit 16, a display unit 17, and a biological information generation unit 18. .
  • the measuring apparatus 10 measures biological information in a region to be examined that is in contact with the measuring unit 16.
  • FIG. 2 is a diagram illustrating an example of a usage state of the measurement device 10, and is a diagram illustrating a state in which a user presses a finger of a hand that is a test site against the measurement device 10.
  • the measurement apparatus 10 measures biological information in a state where the finger is pressed against the measurement unit 16 as shown in FIG.
  • the biological information can be any biological information that can be measured using the biological sensor 13.
  • the measurement device 10 will be described below as an example of measuring the blood flow of a subject, which is information related to blood flow.
  • the pressure detection unit 11 detects the pressure acting on the measurement unit 16.
  • the pressure detection unit 11 is configured by, for example, a piezoelectric element.
  • the pressure detection unit 11 is connected to the control unit 14 and transmits the detected pressure to the control unit 14 as a pressure signal. Accordingly, when the test site is in contact with the measurement unit 16, the pressure detection unit 11 detects the pressure acting on the measurement unit 16 from the test site, and transmits the detected pressure to the control unit 14 as a pressure signal. .
  • the temperature detection unit 12 detects the temperature of the measurement unit 16.
  • the temperature detection part 12 is comprised by well-known temperature sensors, such as a thermocouple, a thermistor, a bimetal, for example.
  • the temperature detection unit 12 is connected to the control unit 14 and transmits the detected temperature to the control unit 14 as a temperature signal. Therefore, when the test site is in contact with the measurement unit 16, the temperature detection unit 12 detects the temperature of the measurement unit 16 based on the contact of the test site, and transmits the detected signal to the control unit 14 as a temperature signal. To do.
  • the biological sensor 13 acquires a biological measurement output from the site to be examined.
  • the biological sensor 13 includes a laser light source 21 and a light receiving unit 22.
  • the laser light source 21 emits laser light based on the control of the control unit 14.
  • the laser light source 21 irradiates, for example, a laser beam having a wavelength capable of detecting a predetermined component contained in blood as measurement light, and is configured by, for example, an LD (laser diode: Laser Diode). .
  • LD laser diode: Laser Diode
  • the light receiving unit 22 receives the scattered light of the measurement light from the test site as a biometric measurement output.
  • the light receiving unit 22 is configured by, for example, a PD (photodiode: Photo Diode).
  • the biological sensor 13 transmits a photoelectric conversion signal of scattered light received by the light receiving unit 22 to the control unit 14.
  • the control unit 14 is a processor that controls and manages the entire measurement apparatus 10 including each functional block of the measurement apparatus 10.
  • the control unit 14 is composed of a processor such as a CPU (Central Processing Unit) that executes a program defining a control procedure, and the program is stored in the storage unit 15 or an external storage medium, for example.
  • a processor such as a CPU (Central Processing Unit) that executes a program defining a control procedure, and the program is stored in the storage unit 15 or an external storage medium, for example.
  • control unit 14 determines whether or not the acquisition of the biological measurement output by the biological sensor 13 is completed. For example, the control unit 14 may determine that the acquisition of the biometric output is completed after a predetermined time has elapsed since the biosensor 13 starts acquiring the biometric output. For example, the control unit 14 may determine that the acquisition of the biometric output is completed when the biometric sensor 13 acquires a sufficient biometric output for measuring the biometric information.
  • control unit 14 controls the laser light emitted from the laser light source 21 when the user measures biological information using the measuring device 10.
  • the control unit 14 controls the laser light emitted from the laser light source 21 based on the pressure and temperature in the measurement unit 16 detected by the pressure detection unit 11 and the temperature detection unit 12, respectively.
  • control of the laser light source 21 by the control unit 14 will be specifically described.
  • the control unit 14 causes the laser light source 21 to emit laser light when the pressure detected by the pressure detection unit 11 is within a predetermined pressure range.
  • the predetermined pressure range can be an arbitrary pressure range in which the pressure acting on the measurement unit 16 from the test site can measure the blood flow rate.
  • the pressure acting on the measurement unit 16 from the test site is the blood flow rate. It is preferable that the pressure range is suitable for the measurement.
  • the pressure range suitable for blood flow measurement is, for example, a pressure range in which an error in the blood flow measurement result falls within a predetermined error range based on a statistical relationship between the pressure and the measurement error.
  • the control unit 14 When the pressure at the measurement unit 16 detected by the pressure detection unit 11 is within a predetermined pressure range, the control unit 14 emits laser light, for example, so that the test site is in contact with the measurement unit 16. When there is no laser beam, it is possible to prevent the laser beam from being erroneously emitted.
  • the erroneous emission refers to the emission of laser light not intended by the user.
  • the control unit 14 emits laser light when the pressure detected by the pressure detection unit 11 is within a pressure range suitable for blood flow measurement, so that an error is predetermined as compared with the actual blood flow rate. Appropriate measurement results that fall within the range can be output to the user.
  • control unit 14 may cause the laser light source 21 to emit laser light when the temperature detected by the temperature detection unit 12 is within a predetermined temperature range.
  • the predetermined temperature range is an arbitrary temperature range in which it is possible to recognize that a person is in contact with the measurement unit 16, and is, for example, a range from 30 degrees to 40 degrees including an average body temperature of the person.
  • the control unit 14 emits laser light, for example, so that the test site is not in contact with the measurement unit 16 Sometimes laser light can be prevented from being erroneously emitted.
  • the control unit 14 is configured such that the pressure detected by the pressure detection unit 11 is within a predetermined pressure range, and the temperature detected by the temperature detection unit 12 is within a predetermined temperature range. Then, laser light is emitted from the laser light source 21. Thereby, it becomes easy to prevent erroneous emission of laser light more reliably. Specifically, it is assumed that, for example, a thin object other than the test site is in contact with the measurement unit 16 and the pressure applied to the measurement unit 16 falls within a predetermined pressure range. In this case, when the control unit 14 emits laser light based only on pressure, there is a possibility that the laser light leaks from around the object in contact with the measurement unit 16.
  • the control unit 14 when the control unit 14 emits laser light based on both pressure and temperature as in the present embodiment, the temperature of the measurement unit 16 does not fall within a predetermined temperature range due to contact with an object. Laser light is not emitted. Therefore, the control unit 14 can more reliably prevent erroneous laser light emission. In particular, depending on the setting of a predetermined temperature range used for the determination of laser light emission, the control unit 14 can further prevent erroneous emission when an object other than a human measurement site comes into contact with the measurement unit 16. Become.
  • control unit 14 may stop the emission of the laser light from the laser light source 21 when the pressure detected by the pressure detection unit 11 is not within the predetermined pressure range in a state where the laser light is emitted. Good.
  • the pressure detected by the pressure detection unit 11 is not within the predetermined pressure range, it is assumed that the user has moved the test site away from the measurement unit 16, for example. In this case, when the control unit 14 continues the emission of the laser light, the emitted laser light is not irradiated on the test site and leaks to the outside of the measuring apparatus 10. In order to prevent this, the control unit 14 may stop the emission of the laser light from the laser light source 21 when the pressure detected by the pressure detection unit 11 is not within a predetermined pressure range.
  • the change in pressure in the measurement unit 16 can be immediately detected by the pressure detection unit 11 when the test site is separated. Therefore, the control unit 14 can immediately stop the emission of the laser beam when the test site is separated from the measurement unit 16 and can prevent the laser beam from leaking outside the measurement apparatus 10. In addition, by stopping the emission of the laser light, an effect of suppressing power consumption when the measurement apparatus 10 cannot measure biological information is also produced.
  • the storage unit 15 can be composed of a semiconductor memory or the like, and stores various information, a program for operating the measuring apparatus 10, and the like, and also functions as a work memory.
  • the storage unit 15 may store the blood flow measured by the measurement device 10 as a history.
  • the measurement part 16 is a part which contacts test regions, such as a finger
  • the measurement part 16 can be comprised with a plate-shaped member, for example. Further, the measurement unit 16 may be formed of a member that is transparent to at least the measurement light and scattered light from the contacted test site.
  • the display unit 17 is a display device including a known display such as a liquid crystal display, an organic EL display, or an inorganic EL display.
  • the display unit 17 displays the biological information generated by the biological information generation unit 18, for example.
  • the biological information generation unit 18 generates biological information based on the output (biological information output) of the light receiving unit 22. As shown in FIG. 1, the biological information generation unit 18 may be configured in the measurement apparatus 10 as an independent functional unit different from the control unit 14 or may be configured as a part of the control unit 14. .
  • the control unit 14 irradiates the living body tissue (test site) with laser light from the laser light source 21 and receives light scattered from the living body tissue by the light receiving unit 22. . Then, the biological information generation unit 18 calculates the blood flow based on the output related to the received scattered light.
  • the biological information generation unit 18 detects a beat signal (also referred to as a beat signal) generated by light interference between scattered light from a stationary tissue and scattered light from a moving blood cell. This beat signal represents the intensity as a function of time. Then, the biological information generation unit 18 converts the beat signal into a power spectrum in which power is expressed as a function of frequency. In the power spectrum of the beat signal, the Doppler shift frequency is proportional to the blood cell velocity, and the power corresponds to the amount of blood cells. And the biometric information generation part 18 calculates
  • FIG. 3 The flow shown in FIG. 3 is started when, for example, the measurement apparatus 10 is in a state where the blood flow volume can be measured by an operation on the measurement apparatus 10. At the start of this flow, no laser light is emitted from the laser light source 21.
  • the control unit 14 first determines whether or not the temperature of the measurement unit 16 detected by the temperature detection unit 12 is within a predetermined temperature range (step S101).
  • control unit 14 determines that the temperature of the measurement unit 16 is not within the predetermined temperature range (No in step S101)
  • the control unit 14 repeats step S101 until it determines that the temperature of the measurement unit 16 is within the predetermined temperature range. .
  • control unit 14 determines that the temperature of the measurement unit 16 is within a predetermined temperature range (Yes in step S101), then the pressure acting on the measurement unit 16 detected by the pressure detection unit 11 is a predetermined value. It is determined whether the pressure is within the range (step S102).
  • step S102 the control unit 14 determines that the pressure acting on the measurement unit 16 is not within the predetermined pressure range (No in step S102), the flow returns to step S101.
  • the control unit 14 causes the laser light source 21 to emit laser light when determining that the pressure acting on the measurement unit 16 is within a predetermined pressure range (Yes in step S102). Due to the emission of the laser light, the light receiving unit 22 receives the scattered light, and acquisition of the biological measurement output in the biological sensor 13 is started (step S103).
  • control unit 14 determines whether or not the pressure acting on the measurement unit 16 detected by the pressure detection unit 11 is within a predetermined pressure range (step S104).
  • control unit 14 determines that the pressure acting on the measurement unit 16 is not within the predetermined pressure range (No in Step S104). Then, this flow returns to step S101.
  • step S104 when the control unit 14 determines that the pressure acting on the measurement unit 16 is within the predetermined pressure range (Yes in step S104), the biological sensor is maintained while the laser light is emitted from the laser light source 21. It is determined whether or not the acquisition of the biometric output by 13 is completed (step S106).
  • control unit 14 determines that the acquisition of the biometric measurement output has not ended (No in step S106)
  • the control unit 14 returns to step S104, and determines whether or not the pressure acting on the measurement unit 16 is within a predetermined pressure range. to decide.
  • Step S106 When the control unit 14 determines that the acquisition of the biometric measurement output is completed (Yes in Step S106), the control unit 14 stops the emission of the laser light from the laser light source 21 (Step S107). In this way, the acquisition of the biometric output in the measurement apparatus 10 is completed.
  • the acquired biometric measurement output is used by the biometric information generation unit 18 to generate biometric information.
  • the measurement apparatus 10 determines whether or not the test site is in contact with the measurement unit 16 based on the pressure and temperature in the measurement unit 16. Then, the control unit 14 causes the laser light source 21 to emit laser light when it is determined that the test site is in contact with the measurement unit 16. Further, the control unit 14 stops the emission of the laser beam when it is determined that the test site is not in contact with the measurement unit 16 based on the pressure in the measurement unit 16. Therefore, the measuring apparatus 10 can prevent the laser from being emitted when the region to be examined is not in contact with the measuring unit 16, and can improve safety.
  • the predetermined temperature range serving as a reference for determining whether or not the test site is in contact with the measurement unit 16 may be determined based on the temperature around the measurement unit 16.
  • the measuring device 10 further includes, for example, a temperature sensor that measures the temperature around the measuring unit 16, and the control unit 14 determines a predetermined temperature range based on the temperature measured by the temperature sensor.
  • the control unit 14 can determine that the test site is in contact with the measurement unit 16 based on the temperature of the measurement unit 16. In such a case, the control unit 14 can determine to increase the predetermined temperature range based on the ambient temperature around the measurement unit 16 measured by the temperature sensor. This makes it easier to prevent the control unit 14 from making an erroneous determination when the test site is in contact with the measurement unit 16 based on the ambient temperature.
  • the determination of the predetermined temperature range may not be based on the ambient temperature of the measurement unit 16.
  • the control unit 14 may determine a predetermined temperature range according to the season with reference to a calendar function provided by itself.
  • the control unit 14 may determine a predetermined temperature range based on temperature information acquired from a communication unit that is separately provided in the measurement apparatus 10.
  • FIG. 4 is a diagram showing an example of a mobile phone equipped with the measuring apparatus 10 of FIG. As shown in FIG. 4A, the mobile phone 30 includes a measuring device 10 on the back side thereof.
  • FIG. 4B is a diagram illustrating an example of a case where the user performs measurement of biological information using the mobile phone 30 including the measurement device 10.
  • the user causes the measurement device 10 to measure biological information by bringing a finger into contact with the measurement unit 16 of the measurement device 10.
  • the measurement device 10 When the user uses the mobile phone 30 including the measurement device 10 to measure biometric information, the measurement device 10 activates a dedicated application for the user to measure biometric information using the mobile phone 30. Thus, measurement of biological information may be started. In addition, the measuring device 10 may automatically start measurement of biological information when the measurement unit 16 detects a contact pressure. In this case, the user can start measurement of biological information by bringing the finger into contact with the measurement unit 16 without activating the application.
  • the functions of the functional units of the measuring device 10 shown in FIG. 1 may be included in the functional units of the electronic device.
  • the measurement apparatus 10 may use a display included in the mobile phone 30 as the display unit 17.
  • the arrangement of the measuring device 10 in the mobile phone 30 is not limited to that shown in FIG.
  • the measuring device 10 may be disposed on another part of the back surface of the mobile phone 30, or may be disposed on the surface or side surface of the mobile phone 30.
  • the electronic device on which the measuring apparatus 10 is mounted is not limited to the mobile phone 30.
  • the measuring apparatus 10 can be mounted on a wide variety of electronic devices such as a portable music player, a notebook computer, a wristwatch, a tablet terminal, and a game machine.
  • the biometric information generation part 18 with which the measuring apparatus 10 is provided produces
  • production of biometric information is the biometric information with which the measurement apparatus 10 is provided. It is not restricted to the case where the production
  • a server device connected to the measurement apparatus 10 via a wired or wireless network or a combination thereof includes a functional unit corresponding to the biological information generation unit 18, and the generation of biological information is a server having this functional unit. It may be performed on the device.
  • the measurement apparatus 10 acquires the biometric information output by the biometric sensor 13, and transmits the acquired biometric information output to the server apparatus from a separately provided communication unit. Then, the server device generates biometric information based on the biometric information output, and transmits the generated biometric information to the measurement device 10. The user can browse the biometric information received by the measurement device 10 by displaying the biometric information on the display unit 17. As described above, when the server device generates biometric information, the measurement device 10 can be reduced in size and the like as compared with the case where all the functional units illustrated in FIG. 1 are realized on one measurement device 10. .

Abstract

　La présente invention concerne un dispositif de mesure pour mettre un site de sujet en contact avec une unité de mesure (16) et mesurer des informations biologiques qui est pourvu d'une unité de détection de pression (11) pour détecter une pression exercée sur l'unité de mesure (16), une source de lumière laser (21) pour émettre une lumière laser, une unité de réception de lumière (22) pour recevoir une lumière laser diffusée depuis le site de sujet, une unité de génération d'informations biologiques (18) pour générer des informations biologiques sur la base de la sortie de l'unité de réception de lumière (22), et une unité de commande (14), et l'unité de commande (14) amène une lumière laser à être émise depuis la source de lumière laser (21) lorsque la pression détectée par l'unité de détection de pression (11) est dans une plage de pression prédéterminée.
PCT/JP2015/002655 2014-05-27 2015-05-26 Dispositif de mesure et procédé de mesure WO2015182125A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2014-109371 2014-05-27
JP2014109371A JP2015223289A (ja) 2014-05-27 2014-05-27 測定装置及び測定方法

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WO2015182125A1 true WO2015182125A1 (fr) 2015-12-03

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009001449A1 (fr) * 2007-06-27 2008-12-31 Pioneer Corporation Dispositif d'écoute
JP2009034366A (ja) * 2007-08-02 2009-02-19 Seiko Epson Corp 脈拍計、電子機器、脈拍測定方法、脈拍測定プログラム、および記憶媒体
JP2009201895A (ja) * 2008-02-29 2009-09-10 Seiko Instruments Inc 脈波検出装置及び脈波検出方法

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009001449A1 (fr) * 2007-06-27 2008-12-31 Pioneer Corporation Dispositif d'écoute
JP2009034366A (ja) * 2007-08-02 2009-02-19 Seiko Epson Corp 脈拍計、電子機器、脈拍測定方法、脈拍測定プログラム、および記憶媒体
JP2009201895A (ja) * 2008-02-29 2009-09-10 Seiko Instruments Inc 脈波検出装置及び脈波検出方法

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