WO2015154304A1 - 精密过滤医用输液接头 - Google Patents

精密过滤医用输液接头 Download PDF

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Publication number
WO2015154304A1
WO2015154304A1 PCT/CN2014/075148 CN2014075148W WO2015154304A1 WO 2015154304 A1 WO2015154304 A1 WO 2015154304A1 CN 2014075148 W CN2014075148 W CN 2014075148W WO 2015154304 A1 WO2015154304 A1 WO 2015154304A1
Authority
WO
WIPO (PCT)
Prior art keywords
filter
joint
connector
medical infusion
housing
Prior art date
Application number
PCT/CN2014/075148
Other languages
English (en)
French (fr)
Inventor
陈永曦
Original Assignee
福建省百仕韦医用高分子股份有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 福建省百仕韦医用高分子股份有限公司 filed Critical 福建省百仕韦医用高分子股份有限公司
Priority to PCT/CN2014/075148 priority Critical patent/WO2015154304A1/zh
Priority to CN201480078730.1A priority patent/CN106413775B/zh
Publication of WO2015154304A1 publication Critical patent/WO2015154304A1/zh

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/02—Access sites
    • A61M39/04—Access sites having pierceable self-sealing members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/02—Access sites
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/165—Filtering accessories, e.g. blood filters, filters for infusion liquids
    • A61M2005/1652—Filter with duct, e.g. filtering element incorporated in a flow line, tube, duct
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/165—Filtering accessories, e.g. blood filters, filters for infusion liquids
    • A61M2005/1657—Filter with membrane, e.g. membrane, flat sheet type infusion filter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/02—Access sites
    • A61M2039/0205—Access sites for injecting media
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/75—General characteristics of the apparatus with filters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/75—General characteristics of the apparatus with filters
    • A61M2205/7545—General characteristics of the apparatus with filters for solid matter, e.g. microaggregates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/165—Filtering accessories, e.g. blood filters, filters for infusion liquids

Definitions

  • the invention relates to a medical infusion joint, in particular to a precision filtering medical infusion joint.
  • Intravenous infusion through a disposable infusion set is an indispensable important method and means in clinical treatment.
  • the infusion set is equipped with a filter membrane, but the filter membrane installed on the infusion set can only filter diameters larger than 5 microns. Particles, particles of diameter equal to or less than 5 microns, cannot be filtered by disposable infusion sets.
  • the main production processes of the particles are: 1. Plastic particles, adsorbents in the infusion bag during the production process; 2. Rubber particles, which are produced when the needles are inserted into the rubber plugs; 3. Fibers, batt, dust particles, in the bag opening Produced by contact with the indoor environment during the puncture; four, carbon black particles, some of the particles present in the pharmaceutical preparation itself; five, insoluble rubber particles, due to the limitation of the purification process, produced in the production process of Chinese herbal medicine preparation; six, crystal particles, in the drug When the storage condition changes and the storage time increases, the glass particles are scattered particles when the ampoule is cut; 8. The drug particles, when the drug is added, the dissolution of some powders is incomplete, the physical and chemical effects between the drugs occur, and the solvent Produced by changes, pH changes, and the like.
  • the filter membrane is unable to filter the particles generated by the bag opening, the puncture rubber plug, etc. during the infusion process because of the relatively advanced setting. Once the particles are not filtered out, they will enter the human body through the infusion, which will cause great harm to the human body.
  • the object of the present invention is achieved by the following route.
  • the utility model comprises a joint base which is connected with the extracorporeal indwelling catheter assembly and a docking joint which is connected with the medical liquid infusion device.
  • the inner base of the joint base and the joint has an infusion passage which communicates with each other, and the main points of the composition are: a bridge between the joint base and the joint.
  • the precision filter comprises a casing, wherein the inner cavity of the casing is an infusion channel, wherein a filter module is arranged, the casing has a venting hole, and the venting hole is provided with a venting plug with a gas permeable and liquid blocking.
  • the liquid outlet end of the infusion set is a puncture needle or an outer conical joint, inserted into the docking joint of the present invention, and connected to the external infusion and infusion device via the filter and the joint base, so that the liquid passes through the infusion device first.
  • the liquid is further filtered through the filter membrane module, and at the same time, the fine bubbles in the liquid are filtered out, and the bubbles are filtered through the filter to cover the permeable and impervious filter membrane, and are removed from the vent hole and purified.
  • the liquid enters the blood vessels of the human body, thus greatly reducing the hidden trouble of the infusion reaction caused by the particles.
  • the object of the present invention can also be achieved by the following means.
  • the bottom of the inner cavity of the casing has a funnel shape, and the filter membrane assembly is located above the triangular cavity of the lower part of the funnel.
  • the bottom of the triangular cavity of the collected filtrate is connected to the funnel mouth, and the funnel mouth is exposed outside the casing, and the inner core is connected with the triangular cavity and is infusion. aisle.
  • the funnel mouth has a conical shape forming a male joint, and the upper part of the male joint is spaced apart from the outer bottom surface of the casing at a certain distance, and a convex ring is arranged, and the male joint and the convex ring constitute a joint base.
  • the male connector and the male ring can be directly socketed directly to the hose on the indwelling device. Or further specific
  • the outer joint of the male joint is connected with a tightening nut, and the tightening nut is hung on the convex ring, and the parts contacting the convex ring are conjugate with each other, and the male joint, the convex ring and the tightening nut form a joint Pedestal.
  • the convex ring facilitates the insertion of the male connector into the connector on the instrument, and the convex conjugate surface is tensioned and sealed when the tightening nut is screwed to the connector on the instrument, and the male connector is prevented from coming out of the connector.
  • the configuration regarding the combination of the housing and the filter assembly can be further optimized to:
  • the housing has an upper cover, and after the assembled filter assembly is placed in the inner cavity of the housing, the upper cover is fixed to the outer casing, and the upper cover is provided with a structure connected with the barge joint, the outer side of the filter module or the outer side and the bottom of the filter module There is a gap between the filtrate and the corresponding surface of the inner cavity of the casing. Further optimization is:
  • the top opening edge of the casing is provided with an inner annular step, and the upper edge of the filter assembly is abducted, and the flange corresponds to the inner annular step.
  • the filter assembly is positioned and fixedly sealed in the inner cavity of the casing by the corresponding structure.
  • the inner and outer sides of the membrane module can only communicate through the membrane.
  • the filter module can be further optimized to:
  • the membrane module comprises a filter holder and a filter membrane, and the filter membrane is adhered to the outer side of the filter holder or to the outer side and the bottom surface of the filter holder, and the filter holder is either a tetrahedral frame or a a cylindrical frame.
  • the membrane module includes a filter holder and a filter membrane.
  • Four or six or eight sheet frames are arranged side by side and fixed to form a filter holder.
  • the filter membrane is attached to each sheet frame, and the top of the membrane module.
  • the central opening and the bottom of the bottom are open, and the filtrate passage passes through the interval between the two two sheet-like frames, respectively, to the left and right through an even number of filter membranes, and passes through the gap between the outer filter membrane and the corresponding side surface of the housing inner cavity, and passes downward through the bottom of the filter assembly. Opening on both sides, connecting the bottom outlet of the inner cavity of the housing.
  • the filtrate has two filtration channels, each of which passes through at least two membranes, and the filtration is thorough and does not affect the flow rate of the filtrate.
  • the filter holder is composed of left and right side brackets and an intermediate bracket
  • the side bracket has a Japanese-shaped frame
  • the lower edge of the bracket has an abduction single flange
  • the filter film is applied to the right side frame surface of the bracket
  • the middle bracket has a lateral direction.
  • U-shaped and having a certain width the U-shaped two side walls are hollowed into a Japanese character frame 261, and the upper edges of the U-shaped side walls have symmetric abduction flange sides, and the flange corners are provided with a step for the side brackets to be fixed thereto
  • Positioning the filter film is applied to the U-shaped outer frame surface, and the side bracket and the intermediate bracket are combined to form a parallel multi-layered fence-like filter layer.
  • the top and the sides of the filter module are open at the top, and the bottom openings of the adjacent two filter membranes are left and right.
  • the filtrate channel is opened through the center of the top and both sides, each passing through a filter membrane, passing downward through the bottom opening of each of the adjacent two filter membranes, and continuing to the bottom outlet of the inner cavity of the casing.
  • the volume can be made as small as possible, while the filtration area is as large as possible, and the filter capacity of the filter is enhanced.
  • the upper cover of the casing has a triangular roof surface, and each of the inclined surfaces is connected with a barge joint to form a liquid input joint in the form of a double branch.
  • the input connector can also be an infusion connector with different functions, such as a needleless connector, a positive pressure connector, and the like.
  • the liquid input connector can be separately manufactured and then fixed to the filter upper cover fixing hole, and the connector outlet port is directly connected to the other side of the filter upper cover.
  • the infusion connector housing can also be manufactured integrally with the filter cover.
  • the present invention has the following advantages over the prior art: the filter particles are relatively thorough, and the filtrate has a fast flow rate, a compact structure, and is convenient to use.
  • FIG. 1 is a schematic front view showing the structure of a precision filtration medical infusion connector according to Embodiment 1 of the present invention
  • FIG. 2 is a schematic structural view showing a precision filtration medical infusion connector and an indwelling needle according to Embodiment 1 of the present invention
  • FIG. 3 is a schematic structural view showing the connection of a precision filtration medical infusion connector and a hose according to Embodiment 1 of the present invention
  • FIG. 4 is a schematic perspective cross-sectional view showing the structure of a filter in a precision filtration medical infusion joint according to Embodiment 1 of the present invention
  • FIG. 5 is a schematic perspective view showing the structure of a filter upper cover in the precision filtration medical infusion joint according to Embodiment 1 of the present invention
  • Figure 6 is a schematic perspective view showing the structure of a filter housing in the precision filtration medical infusion connector according to Embodiment 1 of the present invention.
  • Figure 7 is a schematic perspective cross-sectional view showing the structure of a filter housing in a precision filtration medical infusion connector according to Embodiment 1 of the present invention.
  • Figure 8 is a schematic perspective view showing the structure of a filter membrane holder in the precision filtration medical infusion connector according to Embodiment 1 of the present invention.
  • Figure 9 is a schematic perspective view showing the structure of a filter membrane assembly in a precision filtration medical infusion connector according to Embodiment 1 of the present invention.
  • FIG. 10 is a schematic view showing a filtrate passage of a precision filtration medical infusion connector according to Embodiment 1 of the present invention.
  • Figure 11 is a schematic front view showing the structure of a precision filtration medical infusion joint according to a preferred embodiment of the present invention.
  • Figure 12 is a schematic view showing the structure of a precision filtration medical infusion connector and an indwelling needle according to a preferred embodiment of the present invention
  • Figure 13 is a schematic view showing the structure of a precision filtration medical infusion connector and a hose according to a preferred embodiment of the present invention
  • Figure 14 is a schematic view showing the structure of a precision filtration medical infusion connector and a double-branched joint according to a preferred embodiment of the present invention
  • Figure 15 is a schematic perspective cross-sectional view showing the structure of a filter in a precision filtration medical infusion connector according to a preferred embodiment of the present invention.
  • Figure 16 is a schematic perspective cross-sectional view showing another cross-sectional direction of the filter in the precision filtration medical infusion connector according to the preferred embodiment of the present invention.
  • Figure 17 is a schematic perspective view showing the structure of a filter upper cover in a precision filtration medical infusion joint according to a preferred embodiment of the present invention.
  • Figure 18 is a schematic perspective view showing the structure of a filter housing in a precision filtration medical infusion connector according to a preferred embodiment of the present invention
  • Figure 19 is a schematic perspective view showing the structure of a filter housing cover in a precision filtration medical infusion connector according to a preferred embodiment of the present invention.
  • Figure 20 is a schematic perspective view showing the structure of a filter housing lower cover in a precision filtration medical infusion connector according to a preferred embodiment of the present invention
  • Figure 21 is a schematic perspective cross-sectional view showing the structure of a filter housing lower cover in a precision filtration medical infusion connector according to a preferred embodiment of the present invention
  • Figure 22 is a schematic perspective view showing the structure of a filter cartridge holder side bracket in a precision filtration medical infusion connector according to a preferred embodiment of the present invention
  • Figure 23 is a schematic perspective view showing the structure of a filter cartridge holder intermediate support in a precision filtration medical infusion connector according to a preferred embodiment of the present invention.
  • Figure 24 is a schematic perspective view showing the structure of a filter membrane module in a precision filtration medical infusion connector according to a preferred embodiment of the present invention.
  • Figure 25 is a schematic illustration of the filtrate passage of a precision filtered medical infusion connector in accordance with a preferred embodiment of the present invention.
  • the present invention is composed of a docking 1, a precision filter 2 and a joint base 3, and is made of medical plastic, medical rubber and a filter membrane.
  • the joint base 3 of the present invention that is, the liquid output end, has a conical male joint, which can be inserted and engaged with the external indwelling instrument input port connector 4, and then locked and fixed by the movable tightening nut in the joint base 3 ,as shown in picture 2.
  • the liquid output male connector can also be combined with the connecting device on the indwelling device and directly connected to the connecting hose 5, as shown in FIG.
  • the barge 1 can be in the form of a single branch or a multi-branch, as shown in Figure 1, the two branches, one for the infusion connector and the other for the inner conical interface.
  • the input connector can also be an infusion connector with different functions, such as a needleless connector, a positive pressure connector, and the like.
  • the liquid input connector can be manufactured separately and then fixed to the fixing filter upper cover fixing hole, and the connector outlet port is directly connected to the other side of the filter upper cover.
  • the infusion connector housing can also be manufactured integrally with the filter cover.
  • the precision filter 2 is composed of an upper cover 21, a casing 22, a filter holder 23, a plurality of fine filter membranes 24, a flexible sealing sheet 28, and a plurality of gas permeable, water-impermeable and gas permeable membranes 25.
  • the upper cover has a triangular flat cover and has a convex cover edge 211.
  • the inclined cover wall is provided with a fixing joint 212 for the joint 1 and a plurality of vent holes 213, and the gas permeable membrane 25 is attached to the row.
  • the outlet of the air hole 213 is inside.
  • the outer casing has a rectangular funnel-shaped casing as shown in FIGS. 6 and 7.
  • the funnel cavity 221 is used for installing the filter layer assembly.
  • the lower triangular cavity 225 of the funnel cavity is convenient for collecting and filtering the liquid medicine, and the funnel mouth has a conical shape to form the male joint 222.
  • the upper end of the male connector is spaced apart from the outer bottom surface of the housing, and a triangular convex ring 223 is disposed.
  • the convex ring facilitates insertion of the male connector into the connecting seat of the instrument, and the tapered surface is tensioned and sealed when the connecting nut of the tightening nut and the instrument is screwed.
  • the through hole 224 in the male connector is in communication with the funnel cavity, and the upper edge of the filter housing is provided with a rectangular inner annular step 226.
  • the filter holder 23 has a tetrahedral frame 231 structure, and the upper edge of the bracket has an abduction flange 232.
  • the filter film 24 is attached to the outer frame surface of the bracket except for the frame surface of the frame, as shown in FIG. .
  • the abduction flange on the bracket is conveniently positioned with the annular step of the upper edge of the filter housing, as shown in FIG.
  • the filter combination is such that the filter layer assembly is first assembled, as shown in FIG. 9, and the filter layer assembly is installed into the filter housing, and the upper flange of the filter holder is sleeved and fixed to the annular step in the filter housing. And the sealing is fixed, so that the inner and outer sides of the filter layer assembly can only pass through the filter membrane. After that, the upper cover of the filter is fixedly connected to each branch joint, and the gas permeable membrane is covered at the inner vent hole of the upper cover to lock the movable snail.
  • the cap is inserted into the male connector on the filter housing, and the male connector is forcibly sleeved, and then the upper cover of the filter is assembled, and the filter housing is aligned and sealed, thus forming a complete infusion connector with precise filtering function.
  • the flow of the liquid is as shown in FIG.
  • the present invention is composed of a joint 1, a precision filter 2, and a joint base 3, and is made of medical plastic, medical rubber, and a filter.
  • the joint base 3 of the present invention that is, the liquid output end, has a tapered male joint, which can be inserted and fitted with the external indwelling device input port connector 4, and then locked by the movable tightening nut. .
  • liquid output male connector can also be combined with the connecting device on the indwelling device and directly connected to the connecting hose 5.
  • the liquid input connector may also be in the form of a multi-branch. As shown in FIG. 14, one branch is the infusion connector 6, and the other branch is the inner conical interface 7.
  • the input connector can also be an infusion connector with different functions, such as a needleless connector, a positive pressure connector, and the like.
  • the liquid input connector can be manufactured separately and then fixed to the fixing filter upper cover fixing hole, and the connector outlet port is directly connected to the other side of the filter upper cover.
  • the infusion connector housing can also be manufactured integrally with the filter cover.
  • the precision filter 2 is composed of an upper cover 21, a casing 22, a casing cover 29, a lower cover 26, and left and right side supports of the filter. 233, filter intermediate bracket 234, multiple precision filter membrane 24, soft sealing sheet 28 and a plurality of breathable impervious gas permeable membrane 25 composition.
  • the upper cover has a rectangular flat cover and has a convex cover edge 211.
  • the cover wall is provided with an infusion joint mounting fixing hole 212, and a plurality of vent holes 213 are provided, and the gas permeable membrane 25 is covered in the exhaust gas. Export.
  • the outer casing as shown in Figure 18, has an upper U-shaped wall 227 with an inner flange 228 at the lower edge of the wall.
  • the outer casing cover 29, as shown in Fig. 19, is a rectangular plate having a certain thickness.
  • the lower cover 24, as shown in Figs. 20 and 21, has a funnel-shaped housing and a funnel cavity 221 It is convenient to collect the filtering liquid, and the funnel mouth has a conical shape to form a male joint 222, and the upper end of the male joint is spaced apart from the bottom of the lower cover by a triangular convex ring 223
  • the convex ring facilitates insertion of the male connector into the connecting seat of the instrument, and is tensioned when the tightening nut and the connecting seat of the instrument are screwed to prevent the male connector from coming out of the connecting seat, and the through hole 224 in the male connector communicates with the funnel cavity of the lower cover.
  • Filter holder by left and right side bracket 233 and intermediate bracket 234 As shown in FIG.
  • the side bracket has a zigzag frame 251, the lower edge of the bracket has an abduction single flange 252, and the filter film is applied to the right side frame surface of the bracket;
  • the middle bracket has a lateral U as shown in FIG.
  • the glyph has a certain width, and the U-shaped two side walls are hollowed out into a Japanese character frame 261.
  • the upper edges of the U-shaped side walls have symmetric abduction flange sides 263, and the flange corners are provided with a step 262 for the side brackets to be solidified
  • the filter film is applied to the U-shaped outer frame surface, and the side bracket and the intermediate bracket are combined to form a parallel multi-layer fence-like filter layer, as shown in FIG. 24, the volume can be made as small as possible, and the filter area is as large as possible. , to enhance the filter capacity.
  • the filter combination is such that the filter layer is first assembled, a soft sealing sheet is placed on the U-shaped bottom of the filter housing, the lower side of the sealing sheet is in contact with the upper edge of the inner flange of the outer casing, and the filter layer is installed in the filter housing.
  • the lower surface of the lower flange of the left and right side of the filter is in contact with the upper edge of the inner flange of the outer casing, one end of the filter layer is in contact with the sealing piece, and the other end of the filter layer is covered with another sealing piece, and the lower side of the sealing piece is flush with the upper side of the outer casing flange Cover the outer cover, align with the outer casing, and then press it through the outer cover, so that the two ends of the filter layer are in close contact with the soft sealing piece to achieve sealing, and the left and right side brackets of the filter layer and the outer casing flange It can be sealed by glue or by welding, so that the upper and lower sides of the filter layer can only pass through the filter membrane.
  • the upper cover of the filter is fixedly connected to each branch joint, and the gas permeable membrane is covered at the vent hole on the inner side of the upper cover, and the movable locking nut is placed on the lower joint of the filter cover, and the male joint is protruded.
  • the upper and lower covers of the filter have been assembled, and the filter casing is aligned and fixed to seal, thus forming a complete infusion connector with precise filtering function.
  • the flow of liquid is as shown in Figure 25.

Abstract

一种精密过滤医用输液接头，包括与体外留置导管组件驳接的接头基座（3）和与药液输液器驳接的驳接头（1），接头基座（3）与驳接头（1）二者内腔中均具有相互连通的输液通道。该医用输液接头包括一种跨接在接头基座（3）和驳接头（1）之间的精密过滤器（2），精密过滤器（2）包括一壳体，壳体内腔为输液通道，其中装设有滤膜组件，壳体上具有排气孔（213），排气孔（213）上塞设有透气阻液的排气塞。该医用输液接头具有过滤微粒较彻底，且滤液流速较快，结构紧凑，使用方便的优点。

Description

精密过滤医用输液接头 说明书内容
技术领域
本发明涉及一种医用输液接头,特别是一种精密过滤医用输液接头。
背景技术
通过一次性输液器进行的静脉输液是临床治疗中不可缺少的重要方法和手段，输液器上安设有过滤膜,但是这种安设在输液器上的过滤膜仅仅能够过滤直径大于5微米的微粒，直径为等于和小于5微米的微粒，一次性输液器是无法过滤的。
微粒的主要产生过程有：一、塑料微粒，输液袋在生产过程中的吸附物；二、橡胶微粒，在插瓶针穿刺胶塞时产生；三、纤维、毛絮、尘埃粒子，在开袋与穿刺期间与室内环境接触产生；四、碳黑微粒，一些药物制剂本身存在的微粒；五、不溶性胶粒，由于提纯工艺的限制，在中草药制剂生产过程中产生；六、结晶体微粒，在药物存储条件变化和存储时间增加的情况下产生；七、玻璃碎屑微粒，是切割安瓿时散落的微粒；八、药物微粒，添加药物时，因一些粉剂溶解不完全、药物间发生理化作用、溶媒改变、pH值变化等而产生。
由此可见,这种过滤膜由于设置较靠前,还无法过滤输液过程中的开袋、穿刺胶塞等所产生的微粒。而微粒一旦未被滤除，经过输液进入人体，将对人体造成很大危害。
发明内容
本发明的目的在于克服现有技术中的不足之处，而提供一种过滤微粒较彻底的精密过滤医用输液接头。
本发明的目的是通过以下途径来实现的。
精密过滤医用输液接头， 包括与体外留置导管组件驳接的接头基座和与药液输液器驳接的驳接头，接头基座与驳接头二者内腔中均具有相互连通的输液通道，其组成要点在于：还包括一种跨接在接头基座和驳接头之间的 精密过滤器，精密过滤器包括一壳体，壳体内腔为输液通道，其中装设有滤膜组件，壳体上具有排气孔，排气孔上塞设有透气阻液的排气塞 。
这样， 输液时，输液器上出液端即穿刺针管或外圆锥接头，插入本发明的驳接头，经由过滤器以及接头基座与人体外输液留置器械相连通，这样，药液先通过输液器，再经过具精密过滤功能输液接头，药液经过滤膜组件进一步过滤，同时滤除药液中细微气泡，滤除气泡透过过滤器上盖上透气不透水的滤膜，从排气孔排除，净化药液才进入人体血管内，如此，大大可降低了由于微粒所导致的输液反应隐患。
本发明的目的还可以通过以下途径来实现。
壳体内腔底部呈一种漏斗状,滤膜组件位于漏斗下部三角腔之上,收集滤液的三角腔底部接漏斗嘴,漏斗嘴突露在壳体外,其内芯中空与三角腔连通并为输液通道。
漏斗嘴呈一圆锥形构成阳接头，阳接头上部靠近壳体外底面一定间距，设置有一种凸环，此阳接头以及凸环组成接头基座。这种阳接头以及凸环可以直接与留置器械上的软管直接套接。或者进一步具体为
阳接头外活动连接有紧定螺帽，此紧定螺帽挂支在凸环上，其与凸环触接的部位彼此互为共轭，此阳接头、凸环以及紧定螺帽组成接头基座。
凸环便于阳接头插入器械上连接座后，在紧定螺帽与器械上连接座旋接时凸环共轭面被拉压密封，并防止阳接头脱出连接座。
关于壳体与滤膜组件组合的构造可以进一步优化为：
壳体具有上盖，组装好的滤膜组件放入壳体内腔后，上盖与壳体固接，上盖上设置有与驳接头连接的构造，滤膜组件外侧或者滤膜组件外侧以及底部与壳体内腔对应面之间具有滤液流动的间隙。进一步的优化是：
壳体顶部开口边缘设有内环形阶梯，滤膜组件上缘外展凸缘，此凸缘与此内环形台阶对应，滤膜组件通过此对应构造定位并固接密封在壳体内腔中。
如此滤膜组件内外侧只能透过滤膜互通。
关于滤膜组件可以进一步优化为：
滤膜组件包括滤膜支架和过滤膜，过滤膜或者覆贴在滤膜支架外侧面上或者覆贴在滤膜支架外侧面以及底面上，滤膜支架或者呈一种四面体形框架，或者呈一种圆筒形框架。
还可以进一步优化为：
滤膜组件包括滤膜支架和过滤膜，共有四张或者六张或者八张片状框架左右间隔排列并固接组成滤膜支架，过滤膜覆贴在每张片状框架上，滤膜组件顶部中央开口、底部两侧开口，滤液通道经由中间两张片状框架的间隔，分别向左右透过偶数张滤膜，经过外侧滤膜与壳体内腔对应侧面的间隙，向下通过滤膜组件底部的两侧开口，接续壳体内腔底部出口。
这样，滤液具有两个过滤通道，每个通道均经过至少两张滤膜，过滤较彻底且不影响滤液的流速。
也可以是这样：滤膜支架由左右侧支架和中间支架构成，侧支架具有日字形框架，支架下缘具有外展单凸缘，过滤膜覆贴于支架右侧框面，中间支架具有侧向U字形，并具有一定宽度，U形两侧壁镂空成日字框架261，U形两侧壁上缘具有对称外展凸缘边，凸缘边角设有一阶梯，以便侧支架与之固接定位，过滤膜覆贴于U形外侧框面，侧支架与中间支架组合固接构成平行多层栅栏状过滤层，滤膜组件顶部中央以及两侧开口，左右各相邻两滤膜的底部开口，滤液通道经由顶部中央以及两侧开口，各经过一张滤膜，向下通过左右各相邻两滤膜的底部开口，接续壳体内腔底部出口。
这样，可实现体积尽可能小，而过滤面积尽可能大，强化过滤器过滤能力。
壳体上盖呈一种三角形屋顶面，每个斜面上连接一种驳接头，组成双支路形式的液体输入接头。
其中一支路可以是输液接头，另一支路可以是内圆锥接口。输入接头还可以是具不同功能的输液接头，例如无针接头、正压接头等。液体输入接头可以是单独制造，再固接在过滤器上盖固定孔上，接头出液口直通到过滤器上盖另一侧。输液接头外壳还可以与过滤器上盖一体制造。
综上所述，本发明相比现有技术具有如下优点：过滤微粒较彻底，且滤液流速较快，结构紧凑，使用方便。
附图说明
图1是本发明实施例1所述 精密过滤医用输液接头的结构示意主视图；
图2是本发明实施例1所述 精密过滤医用输液接头与留置针连接在一起的的结构示意图；
图3是本发明实施例1所述 精密过滤医用输液接头与软管连接的结构示意图；
图4是本发明实施例1所述 精密过滤医用输液接头中的过滤器结构示意立体剖视图 ；
图5是本发明实施例1所述 精密过滤医用输液接头中的过滤器上盖结构示意立体图 ；
图6是本发明实施例1所述 精密过滤医用输液接头中的过滤器壳体结构示意立体图 ；
图7是本发明实施例1所述 精密过滤医用输液接头中的过滤器壳体结构示意立体剖视图 ；
图8是本发明实施例1所述 精密过滤医用输液接头中的过滤器滤膜支架结构示意立体图；
图9是本发明实施例1所述 精密过滤医用输液接头中的过滤器滤膜组件结构示意立体图；
图10是本发明实施例1所述 精密过滤医用输液接头的滤液通道示意图；
图11是本发明最佳实施例所述 精密过滤医用输液接头的结构示意主视图；
图12是本发明最佳实施例所述 精密过滤医用输液接头与留置针连接在一起的的结构示意图；
图13是本发明最佳实施例所述 精密过滤医用输液接头与软管连接的结构示意图；
图14是本发明最佳实施例所述 精密过滤医用输液接头与双支路驳接头连接的结构示意图；
图15是本发明最佳实施例所述 精密过滤医用输液接头中的过滤器结构示意立体剖视图；
图16是本发明最佳实施例所述 精密过滤医用输液接头中的过滤器另一个剖视方向的结构示意立体剖视图；
图17是本发明最佳实施例所述 精密过滤医用输液接头中的过滤器上盖结构示意立体图；
图18是本发明最佳实施例所述 精密过滤医用输液接头中的过滤器壳体结构示意立体图；
图19是本发明最佳实施例所述 精密过滤医用输液接头中的过滤器壳体盖板结构示意立体图；
图20是本发明最佳实施例所述 精密过滤医用输液接头中的过滤器壳体下盖结构示意立体图 ；
图21是本发明最佳实施例所述 精密过滤医用输液接头中的过滤器壳体下盖结构示意立体剖视图 ；
图22是本发明最佳实施例所述 精密过滤医用输液接头中的过滤器滤膜支架侧支架结构示意立体图 ；
图23是本发明最佳实施例所述 精密过滤医用输液接头中的过滤器滤膜支架中间支架结构示意立体图 ；
图24是本发明最佳实施例所述 精密过滤医用输液接头中的过滤器滤膜组件结构示意立体图 ；
图25是本发明最佳实施例所述 精密过滤医用输液接头的滤液通道示意图 。
标号说明
1 驳接头； 2过滤器； 21上盖； 211凸出盖缘； 212固定孔； 213排气孔 ；22外壳 ；221漏斗腔； 222阳接头； 223凸环 ；224通孔； 225三角腔 ；226内环形阶梯； 227U形壁； 228内凸缘； 23滤膜支架； 231四面体形框架 ；232外展凸缘 ；233左右侧支架； 234中间支架； 24滤膜； 25 透气膜； 251日字形框架； 252凸缘； 26下盖； 261日字框架 ；262阶梯 ；263凸缘边 ；28密封片 ；29外壳盖板； 3 接头基座； 4连接座 ；5软管； 6输液接头； 7内圆锥接口。
下面结合附图对本发明进行更详尽的描述
具体实施方式
实施例1
如图1所示，本发明由驳接1、精密过滤器2和接头基座3组成，采用医用塑料、医用橡胶和滤膜制成。本发明的接头基座3，即液体输出端，具有锥形阳接头，可与人体外留置器械输入口连接座4插接配合，再由接头基座3中的活动紧定螺帽锁紧固定，如图2所示。液体输出端阳接头还可以与留置器械上连接座合二为一，直接与连接软管5固接，如图3所示。
其中驳接头1可以单支路形式，也可以是多支路形式，如图1所示双支路，一支路是输液接头，另一支路是内圆锥接口。输入接头还可以是具不同功能的输液接头，例如无针接头、正压接头等。液体输入接头可以是单独制造，再固接在精密过滤器上盖固定孔上，接头出液口直通到过滤器上盖另一侧。输液接头外壳还可以与过滤器上盖一体制造。
如图4所示，精密过滤器2由上盖21、外壳22、滤膜支架23、多片精密滤膜24、软性密封片28和多片透气不透水透气膜25组成。
上盖如图5所示，呈三角形扁平盖，具有凸出盖缘211，倾斜盖壁设置有驳接头1安装固定孔212，并设置有多个排气孔213，透气膜25覆贴在排气孔213内出口。
外壳如图6、7所示，具有一矩形漏斗状壳体，漏斗腔221用于安装过滤层组件，漏斗腔下部三角腔225便于汇集过滤药液，漏斗嘴呈一圆锥形构成阳接头222，阳接头上端部距离壳体外底面一定间距，设置有一三角形凸环223，凸环便于阳接头插入器械上连接座后，在紧定螺帽与器械上连接座旋接时锥面被拉压密封，并防止阳接头脱出连接座，阳接头内通孔224与漏斗腔连通，过滤器外壳上边缘设有矩形内环形阶梯226。
滤膜支架23如图8所示，具有四面体形框架231结构，支架上缘具有外展凸缘232，除了框架上框面外，过滤膜24覆贴于支架外侧框面，如图9所示。支架上外展凸缘方便与过滤器外壳上边缘环形阶梯固接定位，如图4所示。
过滤器组合是这样的，首先组合出过滤层组件，如图9所示，再将过滤层组件安装进过滤器外壳中，滤膜支架上凸缘与过滤器外壳内环形阶梯相套接固定，并固接密封，如此过滤层组件内外侧只能透过滤膜互通，之后，过滤器上盖组合固接好各支路接头，在上盖内侧透气孔处覆贴好透气膜，将活动锁定螺帽套入过滤器外壳上阳接头，强制套过阳接头凸环，然后盖上过滤器已组合好的上盖，对齐过滤器外壳后固接密封，如此构成完整具精密过滤功能输液接头。接头在使用过程中，液体流向如图10所示。
本实施例未述部分与现有技术相同。
最佳实施例
如图11所示，本发明由驳接头1、精密过滤器2和接头基座3组成，采用医用塑料、医用橡胶和滤膜制成。
如图12所示，本发明的接头基座3，即液体输出端，具有锥形阳接头，可与人体外留置器械输入口连接座4插接配合，再由活动紧定螺帽锁紧固定。
如图13所示，液体输出端阳接头还可以与留置器械上连接座合二为一，直接与连接软管5固接。
其中液体输入接头也可以是多支路形式，如图14所示，一支路是输液接头6，另一支路是内圆锥接口7。输入接头还可以是具不同功能的输液接头，例如无针接头、正压接头等。液体输入接头可以是单独制造，再固接在精密过滤器上盖固定孔上，接头出液口直通到过滤器上盖另一侧。输液接头外壳还可以与过滤器上盖一体制造。
如图15、图16所示，精密过滤器2由上盖21、外壳22、外壳盖板 29 、下盖 26 、滤膜左右侧支架 233 、滤膜中间支架 234 、多片精密滤膜 24 、软性密封片28和多片透气不透水透气膜 25 组成。
上盖如图17所示，呈矩形扁平盖，具有凸出盖缘211，盖壁设置有输液接头安装固定孔212，并设置有多个排气孔213，透气膜 25 覆贴在排气内出口。
外壳如图18所示，具大写U形壁 227 ，同时壁下缘具有一内凸缘 228 。
外壳盖板 29 如图19所示，是一具有一定厚度矩形板。
下盖24如图20 、21 所示，具有一漏斗状壳体，漏斗腔 221 便于汇集过滤药液，漏斗嘴呈一圆锥形构成阳接头 222 ，阳接头上端部距离下盖底一定间距，设置有一三角形凸环 223 ，凸环便于阳接头插入器械上连接座后，在紧定螺帽与器械上连接座旋接时被拉压，防止阳接头脱出连接座，阳接头内通孔 224 与下盖漏斗腔连通。滤膜支架由左右侧支架 233 和中间支架 234 构成，侧支架如图22所示，具有日字形框架251，支架下缘具有外展单凸缘252，过滤膜覆贴于支架右侧框面；中间支架如图23所示，具有侧向U字形，并具有一定宽度，U形两侧壁镂空成日字框架261，U形两侧壁上缘具有对称外展凸缘边263，凸缘边角设有一阶梯262，以便侧支架与之固接定位，过滤膜覆贴于U形外侧框面，侧支架与中间支架组合固接构成平行多层栅栏状过滤层，如图24所示，可实现体积尽可能小，而过滤面积尽可能大，强化过滤器过滤能力。
过滤器组合是这样的，首先组合出过滤层，在过滤器外壳U形底安放一软性密封片，密封片下边与外壳内凸缘上边相抵接触，再将过滤层安装进过滤器外壳中，过滤器左右侧支架下凸缘下平面与外壳内凸缘上边相抵接触，过滤层一端与密封片接触，再在过滤层另一端覆盖上另一片密封片，密封片下边与外壳凸缘上边平齐，盖上外壳盖板，与外壳对齐后固接，通过外壳盖板挤压，这样过滤层两端侧与软性密封片紧密接触，实现密封，过滤层左右侧支架下凸缘与外壳凸缘可通过胶接密封，也可通过熔接密封，如此，过滤层上下面左右侧只能透过滤膜互通。之后，过滤器上盖组合固接好各支路接头，在上盖内侧透气孔处覆贴好透气膜，将活动锁定螺帽套入过滤器下盖上阳接头，强制套过阳接头凸环，然后盖上过滤器已组合好的上下盖，对齐过滤器外壳后固接密封，如此构成完整具精密过滤功能输液接头。接头在使用过程中，液体流向如图25所示。
本实施例未述部分与现有技术相同。

Claims (10)

  1. 精密过滤医用输液接头， 包括与体外留置导管组件驳接的接头基座和与药液输液器驳接的驳接头，接头基座与驳接头二者内腔中均具有相互连通的输液通道，其特征在于，还包括一种跨接在接头基座和驳接头之间的精密过滤器，精密过滤器包括一壳体，壳体内腔为输液通道，其中装设有滤膜组件，壳体上具有排气孔，排气孔上塞设有透气阻液的排气塞 。
  2. 根据权利要求1所述的精密过滤医用输液接头，其特征在于，壳体内腔底部呈一种漏斗状,滤膜组件位于漏斗下部三角腔之上,收集滤液的三角腔底部接漏斗嘴,漏斗嘴突露在壳体外,其内芯中空与三角腔连通并为输液通道。
  3. 根据权利要求2所述的精密过滤医用输液接头，其特征在于，漏斗嘴呈一圆锥形构成阳接头，阳接头上部靠近壳体外底面一定间距，设置有一种凸环，此阳接头以及凸环组成接头基座。
  4. 根据权利要求3所述的精密过滤医用输液接头，其特征在于，阳接头外活动连接有紧定螺帽，此紧定螺帽挂支在凸环上，其与凸环触接的部位彼此互为共轭，此阳接头、凸环以及紧定螺帽组成接头基座。
  5. 根据权利要求1所述的精密过滤医用输液接头，其特征在于，壳体具有上盖，组装好的滤膜组件放入壳体内腔后，上盖与壳体固接，上盖上设置有与驳接头连接的构造，滤膜组件外侧或者滤膜组件外侧以及底部与壳体内腔对应面之间具有滤液流动的间隙。
  6. 根据权利要求5所述的精密过滤医用输液接头，其特征在于，壳体顶部开口边缘设有内环形阶梯，滤膜组件上缘外展凸缘，此凸缘与此内环形台阶对应，滤膜组件通过此对应构造定位并固接密封在壳体内腔中。
  7. 根据权利要求1或5或6所述的精密过滤医用输液接头，其特征在于，滤膜组件包括滤膜支架和过滤膜，过滤膜或者覆贴在滤膜支架外侧面上或者覆贴在滤膜支架外侧面以及底面上，滤膜支架或者呈一种四面体形框架，或者呈一种圆筒形框架。
  8. 根据权利要求1或5或6所述的精密过滤医用输液接头，其特征在于，滤膜组件包括滤膜支架和过滤膜，共有四张或者六张或者八张片状框架左右间隔排列并固接组成滤膜支架，过滤膜覆贴在每张片状框架上，滤膜组件顶部中央开口、底部两侧开口，滤液通道经由中间两张片状框架的间隔，分别向左右透过偶数张滤膜，经过外侧滤膜与壳体内腔对应侧面的间隙，向下通过滤膜组件底部的两侧开口，接续壳体内腔底部出口。
  9. 根据权利要求1或5或6所述的精密过滤医用输液接头，其特征在于，滤膜组件包括滤膜支架和过滤膜，滤膜支架由左右侧支架和中间支架构成，侧支架具有日字形框架，支架下缘具有外展单凸缘，过滤膜覆贴于支架右侧框面，中间支架具有侧向U字形，并具有一定宽度，U形两侧壁镂空成日字框架261，U形两侧壁上缘具有对称外展凸缘边，凸缘边角设有一阶梯，以便侧支架与之固接定位，过滤膜覆贴于U形外侧框面，侧支架与中间支架组合固接构成平行多层栅栏状过滤层，滤膜组件顶部中央以及两侧开口，左右各相邻两滤膜的底部开口，滤液通道经由顶部中央以及两侧开口，各经过一张滤膜，向下通过左右各相邻两滤膜的底部开口，接续壳体内腔底部出口。
  10. 根据权利要求1所述的精密过滤医用输液接头，其特征在于，壳体上盖呈一种三角形屋顶面，每个斜面上连接一种驳接头，组成双支路形式的液体输入接头。
PCT/CN2014/075148 2014-04-11 2014-04-11 精密过滤医用输液接头 WO2015154304A1 (zh)

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