WO2015118373A1 - Dispositif pour le repliement et la rétraction automatiques d'une ancre - Google Patents

Dispositif pour le repliement et la rétraction automatiques d'une ancre Download PDF

Info

Publication number
WO2015118373A1
WO2015118373A1 PCT/IB2014/002673 IB2014002673W WO2015118373A1 WO 2015118373 A1 WO2015118373 A1 WO 2015118373A1 IB 2014002673 W IB2014002673 W IB 2014002673W WO 2015118373 A1 WO2015118373 A1 WO 2015118373A1
Authority
WO
WIPO (PCT)
Prior art keywords
anchor
tissue
opening
treatment
heating
Prior art date
Application number
PCT/IB2014/002673
Other languages
English (en)
Inventor
David Maier Neustadter
Giora Kornblau
Original Assignee
Calore Medical Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US14/471,435 external-priority patent/US20150066008A1/en
Application filed by Calore Medical Ltd. filed Critical Calore Medical Ltd.
Priority to EP14833531.8A priority Critical patent/EP3102116A1/fr
Publication of WO2015118373A1 publication Critical patent/WO2015118373A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00017—Electrical control of surgical instruments
    • A61B2017/00022—Sensing or detecting at the treatment site
    • A61B2017/00084—Temperature
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
    • A61B2017/00575—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect for closure at remote site, e.g. closing atrial septum defects
    • A61B2017/00623—Introducing or retrieving devices therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
    • A61B2017/00646—Type of implements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
    • A61B2017/00672—Locating means therefor, e.g. bleed back lumen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A61B2017/1205—Introduction devices
    • A61B2017/12054—Details concerning the detachment of the occluding device from the introduction device
    • A61B2017/12068—Details concerning the detachment of the occluding device from the introduction device detachable by heat

Definitions

  • the present disclosure relates generally to a tissue ciosure device, and more specifically, to a device for automatic undeployment and retraction of a removable anchor following treatment of an opening in a tissue wail.
  • Heat may be used to shrink tissue containing collagen in various surgical and diagnostic procedures when treating a patient.
  • heat may be used to close and/or heal perforations, openings, or punctures in the patient's tissue walls.
  • heat may be used to close arteriotomies on blood vessel walls by denaturing collagen within the tissue, thereby shrinking the tissue around the puncture, and/or by inducing blood coagulation.
  • a physician may introduce an anchor device into the patient's blood vessel to temporarily occlude the puncture and provide hemostasis during the closure procedure.
  • the physician may then introduce a tissue closure device into the body to cause shrinkage of the collagenous tissue in the blood vessel wall and/or cause blood coagulation around the puncture site.
  • the physician may remove the anchor device to complete closure of the puncture.
  • the timing of the anchor removal relative to the tissue shrinkage and/or blood coagulation process, as well as the smoothness of the removal motion, can be critical to the success of the closure procedure. Early removal may result in bleeding that will interfere with the tissue heating and/or blood coagulation process, and late removal may result in damage to the newly formed tissue seal at the puncture site, which may lead to reopening of the repaired/closed puncture. Therefore, devices and methods that prevent these potential adverse consequences are desirable.
  • the present disclosure is directed to a tissue closure device that allows automatic undeploymenf and retraction of an anchor element when a predefined trigger associated with a closure procedure is met.
  • Some aspects of the present disclosure include a tissue closure device comprising a treatment applicator and an anchor element for temporarily occluding an opening in a tissue wail while the treatment applicator is used to dose or heal the opening.
  • One application of the tissue closure device and treatment method of the present disclosure is the thermal closure of puncture sites (i.e., arteriotomies) on blood vessel wails.
  • the application of the device and method of the present disclosure are not limited to the blood vasculature, and may be applied to any vessel, duct, canal, tubular structure, and/or cavity in the body. It is to be understood that the term "body canal” in this disclosure refers to any blood vessel, duct, canal, tubular structure, and/or tissue tract within the body.
  • a tissue closure device for treating an opening in a tissue wall ss disclosed.
  • the tissue closure device comprises a removable anchor having an anchor shaft and an occluding element at or near a distai end of the anchor shaft.
  • the occluding element is configured to be deployed within a body canal for temporarily closing an opening in a tissue wail of the body canal.
  • the tissue closure device further comprises a housing configured to be located external to a patient when the occluding element is located within the body canal, a treatment applicator for applying a tissue closure treatment to the opening on the tissue wail, and a controller positioned in the housing and configured to automatically cause the removable anchor to be undeployed from the body canal when a predetermined trigger is met.
  • a method of closing an opening in a tissue wall of a body canal comprises providing a removable anchor comprising an anchor shaft and an occluding element at or near a distal end of the anchor shaft.
  • the occluding element is expandable and collapsible within the body canal.
  • the method further comprises introducing the occluding element into the body canal through the opening in the tissue wall and deploying the anchor thereby causing the occluding element to expand within the body canal.
  • the method further comprises applying a tissue closure treatment to close the opening in the tissue wall, monitoring a treatment parameter associated with the tissue closure treatment, and automatically undeploying the anchor when a predetermined trigger associated with the treatment parameter is met,
  • FIG. 1 iiiustrates an automated undeployment and retraction mechanism of a tissue closure device, in accordance with exemplary embodiments of the present disclosure.
  • FIG. 2 is a flow diagram of the steps of an exemplary vascular closure procedure, in accordance with exemplary embodiments of the present disclosure.
  • the present disclosure describes a tissue closure device comprising an anchor and a treatment applicator for closing or healing an opening in a tissue wail of a body canal.
  • An anchor of the present disclosure is configured to be removable from within the body canal where it is deployed during the treatment of the opening in the tissue wall.
  • the disclosed tissue closure device and treatment method may be employed to close or heal perforations, openings, or punctures in any tissue region of a patient's body.
  • Exemplary embodiments of an anchor of the present disclosure comprise an anchor shaft and an occluding element at or near a distal end of the anchor shaft.
  • the occluding element of the anchor is configured to be expanded and collapsed within the body canal, for example, within a blood vessel.
  • the occluding element of the anchor is inserted into the body canal at the beginning of a tissue closure procedure, through the opening which is to be closed, and removed during or after the closure procedure.
  • the anchor may perform one or more of the following functions when inserted into the body canal: 1 ) provide an indication of the depth of the body canal from the exterior of the body surface; 2) provide mechanical stabilization of the body canal to aid in the insertion of the treatment applicator; 3) provide guidance as to the location of the opening or perforation in the tissue wall of the body canal; and 4) provide temporary hemostasis during part or all of the closure procedure.
  • the anchor After the anchor is inserted into the body canal, it is deployed, which results in expansion, opening, or change in the geometrical shape of the occluding element such that it can no longer pass through the opening in the tissue wall.
  • the expansion of the occluding element may also provide temporary hemostasis.
  • the treatment applicator of the tissue closure device is then activated to close the puncture in the tissue wail.
  • the anchor When a predefined trigger associated with the closure procedure is met, the anchor is undeployed, which results in dosing or collapsing of the occluding element such that it can pass through the opening in the tissue wall.
  • the predefined trigger is a treatment parameter associated with the closure procedure, in one such embodiment, the predefined trigger is an amount of time after the treatment applicator has been activated. In other embodiments, the predefined trigger is a sensed parameter, for example, the temperature of the surrounding tissue region or the temperature of the treatment applicator. In yet other embodiments, the predefined trigger is an amount of time after a sensed parameter, for example, the temperature of the surrounding tissue region or the temperature of the treatment applicator, has reached a predetermined level.
  • undeployment of the anchor device is automated, i.e., once the predefined trigger is met, the anchor device is automatically undeployed. !n other embodiments, undeployment is done manually by the user when the predefined trigger is met. In yet other embodiments, the occluding element of the anchor has a natural tendency to return to its undeployed configuration. Once the anchor device is undeployed, it is retracted from the body canal, i.e. , the anchor device is removed from the inside of the body canal.
  • Exemplary embodiments of the treatment applicator may include a heating element configured to deliver heat to a tissue region containing collagen.
  • the heating element may include any electrical, chemical, mechanical, or other mechanism for causing heat, such as, for example, ultrasound heating, RF heating, laser heating, microwave heating, or any device capable of converting electricity into heat through a process of resistive or Joule heating.
  • the heating element may be encased in a heat-conductive housing or may be otherwise provided to enable the resulting heat to be directed to a target tissue area.
  • Exemplary embodiments may also include a support for positioning the heating element at a location to effect delivery of heat to the tissue region.
  • the support may be an elongate element. The particular shape and construction of an elongated support may vary, and might include, by way of example only, one or more of a tube, rod, shaft, bar, rib, or column.
  • the elongate element as well as the heat- conductive housing may include a lumen with an opening therethrough allowing for placement of the treatment applicator over the anchor shaft.
  • a control system may be housed within a handle of the treatment applicator. Sn some such embodiments, the control system may include a power source, which may be housed within the handle as part of the control system itself, or as a separate component. The power source may be configured for electrical connection to the heating element. In exemplary embodiments, the power source may also be electrically connected to a temperature sensor associated with, or provided in dose proximity to, the heating element.
  • the temperature of the target tissue region, or the temperature of the heating element may be monitored by the temperature sensor, and the power delivered to the heating element may be adjusted to maintain a preselected thermal profile.
  • a microprocessor or a controller may be included and incorporated into control system to modify the power delivered to heating element based on the temperature information received by the controller or the microprocessor from temperature sensor.
  • the temperature sensor itself may include any structure capable of either detecting or measuring temperature, including, for example, a thermometer, bimetal, thermocouple, resistance thermometer, silicon bandgap temperature sensor, or any other arrangement or structure capable of providing feedback indicative of temperature.
  • the tissue closure procedure comprises introducing the occluding element of the anchor into the body canal through the opening that is to be closed and deploying the anchor such that the occluding element expands to temporarily occlude the opening.
  • the tissue region surrounding the opening is then heated with the treatment applicator, i.e., the heating element, to cause shrinkage of collagen- containing tissue and/or cause blood coagulation, thereby closing the opening.
  • the treatment applicator i.e., the heating element
  • the anchor is undeployed.
  • temperature of the target tissue region, and/or the temperature of a distal region of the heating element may be monitored while heat is applied to the tissue.
  • the predefined trigger is a temperature of the target tissue region and/or the temperature of the heating element. In another embodiment, the predefined trigger is an amount of time after the target tissue region and/or the temperature of the heating element reaches a predetermined temperature. Further, in some embodiments, the anchor may be undeployed while the heating element is being energized, in some other
  • the anchor may be undeployed while the tissue region is being heated.
  • Some embodiments of the present disclosure also include an automated retraction mechanism for retracting or removing of the occluding element during or after the undeployment of the anchor.
  • FIG. 1 shows an exemplary embodiment of an automated anchor
  • tissue closure device 10 The automated anchor undeployment and retraction mechanism of tissue closure device 10 allows a user to automate the timing of the undeployment and/or retraction, which may provide more consistency and precision in undeployment and/or retraction than thai achieved by manual actuation, in exemplary embodiments, the anchor undeployment and retraction mechanism is positioned in a housing 20 of tissue closure device 10. An anchor shaft 30 of the removable anchor passes through housing 20 in ciose proximity to the anchor undepioyment and/or retraction mechanism positioned therein.
  • the anchor undepioyment mechanism may include a means for releasing a locking mechanism within the anchor shaft (that locks the anchor in the deployed configuration), thereby allowing the anchor to return to its undepioyed configuration.
  • Means for releasing a locking mechanism may include, for example, rotating, pushing, pulling, bending, or compressing a mechanical element in order to release it from its locked configuration.
  • the anchor undepioyment mechanism may include a means for releasing pressure from a tube within the anchor shaft (that locks the anchor in the deployed configuration), thereby allowing the anchor to return to its undepioyed configuration.
  • Means for releasing pressure from a tube may include, for example, cutting or puncturing the tube, releasing a valve on the tube, or increasing the volume of the tube by moving a plunger.
  • the anchor undepioyment mechanism may include a means for cutting or severing an actuator element (not shown) provided within the anchor shaft.
  • the actuator element may hold the anchor in its deployed configuration, and cutting, severing, or loosening of the actuator element may allow the anchor to return to its undepioyed configuration.
  • the actuator element is a taut wire that holds the anchor in the deployed configuration.
  • the means for cutting the actuator element may include cutting with a sharp blade
  • the anchor undepioyment mechanism may include a spring activated or motor activated mechanism that, when actuated, presses the blade against the anchor shaft with sufficient force to cut through the anchor shaft and sever the actuator eiement running through the anchor shaft.
  • the means for cutting the actuator eiement may include cutting with heat.
  • cutting with heat may include a heating element, e.g., an electrically-heated resistive metal wire 40, as shown in FIG. 1.
  • electrically- heated resistive metal wire 40 may soften the taut wire such that it stretches and is no longer taut
  • cutting with heat may include melting the actuator element with electricaily-heated resistive metal wire 40.
  • the anchor undeployment mechanism may include electrically-heated resistive metal wire 40 mounted on a spring-loaded support 50 such that electrically- heated metal wire 40 presses against anchor shaft 30. When electrically-heated metal wire 40 is actuated, either manually or by a predefined trigger, it melts through anchor shaft 30 and severs the actuator element within anchor shaft 30,
  • the anchor undeployment mechanism may include a separator material 60 positioned around the anchor shaft, on or around which electrically-heated resistive metal wire 40 initially rests.
  • separator material 60 may be a sleeve, sheath, or a tube through which anchor shaft 30 passes and around which electrically-heated resistive metal wire 40 is positioned.
  • separator material 60 may be in the form of a hook or pin which initially restrains the electrically-heated resistive metal wire 40 and does not allow it to contact anchor shaft 30 until separator material 60 has been melted through.
  • the initiation of the undep!oyment mechanism may be controlled by an electronic controller or processor provided in a handle or housing 20 of tissue closure device 10.
  • electronic controller or processor for the undep!oyment mechanism may be the same as the controller used for modifying the power delivered to the heating element of the treatment applicator (for heating the tissue containing collagen).
  • the handle or housing 20 of tissue closure device 10 may comprise a controller or a microprocessor dedicated to the undeployment mechanism.
  • the undep oyment may be initiated at a predefined time after one or more events of the tissue closure procedure. For example, the undeployment may be initiated during the tissue closure procedure, or after the tissue closure procedure is complete.
  • the undeployment may be initiated at a predefined time after the activation of the heating element of the treatment applicator. In other embodiments, the undeployment may be initiated at a predefined time after the heating element of the treatment applicator, or the surrounding tissue, reaches a certain temperature (e.g., the heating element of the treatment applicator reaches a temperature of 90° C, or the surrounding tissue reaches a temperature of 70° C). in such embodiments, the controller of the undeployment mechanism may be operatively coupled to the temperature sensor of the treatment applicator so that the undeployment mechanism can be operatively tied to the temperature of a heating element of the treatment applicator, or the temperature of the surrounding tissue.
  • Some embodiments of the present disclosure may also include an automated retraction mechanism for retraction or removal of the occluding element during or after the undepioyment of the anchor.
  • the occluding element may be retracted while the heating element is being energized.
  • the occluding element may be refracted while the tissue region is being heated.
  • the anchor retraction mechanism may include a carriage 70 and a grasping element 80 connected to carriage 70.
  • Carriage 70 and grasping element 80 may be configured to grasp anchor shaft 30 during or after the undepioyment of the anchor.
  • carriage 70 may be loaded with a spring 90 and held in place by an activation mechanism which, when released, actuates carriage 70.
  • the anchor undepioyment mechanism may serve as an activation mechanism that releases spring 90 and actuates carriage 70 .
  • spring-loaded support 50 of the undepioyment mechanism may act as the activation mechanism for carriage 70.
  • grasping element 80 When actuated, carriage 70 may cause grasping element 80 to grasp anchor shaft 30.
  • grasping element 80 may be a ratchet mechanism, which allows anchor shaft 30 to move in one direction, but resists movement of anchor shaft 30 in the opposite direction.
  • the automated anchor retraction mechanism may comprise a motor and a shaft grasping element.
  • the shaft grasper is actuated to move in such a way as to grasp and retract the anchor.
  • the initiation of the automated retraction mechanism may be controlled by an electronic controller or processor provided in a handle or housing 20 of tissue closure device 10.
  • an electronic controller or processor provided in a handle or housing 20 of tissue closure device 10.
  • the electronic controller or processor for the retraction mechanism may be the same as the controller or processor used for the undeployment mechanism.
  • the controller for initiating the undeployment and/or retraction mechanism may be the same as the controller or processor for modifying the power delivered to the heating element of the treatment applicator (for heating the tissue containing collagen).
  • the retraction may be initiated at a predefined time after one or more events of the tissue closure procedure. For example, the retraction may be initiated during the tissue closure procedure, or after the tissue closure procedure is complete. In some exemplary embodiments, the retraction may be initiated immediately following the undeployment. In other embodiments, the retraction may be initiated at a predefined time after the activation of the heating element of the treatment applicator, or at a predefined time after the heating element of the treatment applicator, or the surrounding tissue, reaches a certain temperature.
  • FIG. 2 illustrates the steps of an exemplary vascular closure procedure using an exemplary vascular anchor comprising an occluding element that is expandable and collapsible within a blood vessel
  • the closure procedure described here, with reference to FIG. 2 may be used to close or heal perforations, openings, or punctures in any tissue region of a patient's body.
  • a first step (step 201 ) of the treatment procedure is introducing the occluding element into the blood vessel through an opening in the blood vessel wail and deploying the anchor thereby causing the occluding element to expand within the blood vessel.
  • the next step (step 203) is applying a vascular closure treatment to close the opening (e.g., an arteriotomy) on the blood vessel wall.
  • the vascular closure treatment comprises applying heat to the tissue region surrounding the opening to cause shrinkage of collagen containing tissue and/or cause blood coagulation.
  • the next step (step 205) is monitoring a treatment parameter (e.g., temperature of the tissue region, temperature of the treatment applicator, or the time that has passed since some treatment related event) associated with the vascular closure treatment. When a predetermined trigger associated with the treatment parameter is met, the vascular anchor is automatically undeployed (step 207).
  • the vascular anchor is automatically retracted from the blood vessel (step 209).
  • tissue closure device 10 may also provide indications of the status of the occluding element, i.e., deployed, undeployed, and retracted. Further, in some embodiments, tissue closure device 10 may also provide indications of the status of the treatment procedure, i.e., started, need to perform action, ended, etc,

Landscapes

  • Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Surgical Instruments (AREA)

Abstract

L'invention concerne un dispositif de fermeture de tissu et un procédé de traitement pour fermer une ouverture dans une paroi tissulaire. Le dispositif de fermeture de tissu comprend un élément chauffant et une ancre amovible comprenant une tige d'ancre et un élément d'occlusion au niveau ou à proximité d'une extrémité distale de la tige d'ancre. L'élément d'occlusion de l'ancre est conçu pour être dilaté et affaissé. Le procédé de traitement comprend l'introduction de l'élément d'occlusion dans un conduit corporel par une ouverture dans une paroi tissulaire du conduit corporel, et le déploiement de l'ancre, de telle sorte que l'élément d'occlusion se dilate pour obturer temporairement l'ouverture dans la paroi tissulaire. La région tissulaire entourant l'ouverture est ensuite chauffée pour provoquer le rétrécissement du tissu contenant du collagène, ce qui contracte l'ouverture dans la paroi tissulaire. Lorsqu'un facteur déclencheur prédéfini associé avec le procédé de traitement se manifeste, l'ancre est automatiquement repliée et rétractée du conduit corporel.
PCT/IB2014/002673 2014-02-09 2014-11-04 Dispositif pour le repliement et la rétraction automatiques d'une ancre WO2015118373A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP14833531.8A EP3102116A1 (fr) 2014-02-09 2014-11-04 Dispositif pour le repliement et la rétraction automatiques d'une ancre

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201461937543P 2014-02-09 2014-02-09
US61/937,543 2014-02-09
US201462015968P 2014-06-23 2014-06-23
US62/015,968 2014-06-23
US14/471,435 2014-08-28
US14/471,435 US20150066008A1 (en) 2013-09-01 2014-08-28 Device for automatic anchor undeployment and retraction

Publications (1)

Publication Number Publication Date
WO2015118373A1 true WO2015118373A1 (fr) 2015-08-13

Family

ID=53777372

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2014/002673 WO2015118373A1 (fr) 2014-02-09 2014-11-04 Dispositif pour le repliement et la rétraction automatiques d'une ancre

Country Status (2)

Country Link
EP (1) EP3102116A1 (fr)
WO (1) WO2015118373A1 (fr)

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994008513A1 (fr) * 1992-10-13 1994-04-28 Taymor Luria Howard Procede et appareil d'obturation vasculaire percutanee
US20020193808A1 (en) * 2000-01-05 2002-12-19 Belef W. Martin Apparatus and methods for delivering a closure device
WO2003094748A1 (fr) * 2002-05-10 2003-11-20 Core Medical, Inc. Bouchon a mandrin et element de type guide fil detachable permettant le positionnement de dispositifs d'obturation vasculaire et ses procedes d'utilisation
WO2009023866A1 (fr) * 2007-08-15 2009-02-19 Cardiodex Ltd. Systèmes et procédés pour fermeture de perforation
US20090163780A1 (en) * 2007-12-21 2009-06-25 Microvention, Inc. System And Method For Locating Detachment Zone Of A Detachable Implant
WO2011057282A2 (fr) * 2009-11-09 2011-05-12 Cardiovascular Technologies, Inc. Dispositifs de fermeture de tissu, dispositif et systèmes pour leur pose, coffrets et méthodes pour ceux-ci

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994008513A1 (fr) * 1992-10-13 1994-04-28 Taymor Luria Howard Procede et appareil d'obturation vasculaire percutanee
US20020193808A1 (en) * 2000-01-05 2002-12-19 Belef W. Martin Apparatus and methods for delivering a closure device
WO2003094748A1 (fr) * 2002-05-10 2003-11-20 Core Medical, Inc. Bouchon a mandrin et element de type guide fil detachable permettant le positionnement de dispositifs d'obturation vasculaire et ses procedes d'utilisation
WO2009023866A1 (fr) * 2007-08-15 2009-02-19 Cardiodex Ltd. Systèmes et procédés pour fermeture de perforation
US20090163780A1 (en) * 2007-12-21 2009-06-25 Microvention, Inc. System And Method For Locating Detachment Zone Of A Detachable Implant
WO2011057282A2 (fr) * 2009-11-09 2011-05-12 Cardiovascular Technologies, Inc. Dispositifs de fermeture de tissu, dispositif et systèmes pour leur pose, coffrets et méthodes pour ceux-ci

Also Published As

Publication number Publication date
EP3102116A1 (fr) 2016-12-14

Similar Documents

Publication Publication Date Title
JP6936283B2 (ja) 大容量の組織を縮小して摘出するシステム及び方法
US7815640B2 (en) Apparatus and methods for closing vascular penetrations
US8021359B2 (en) Transseptal closure of a patent foramen ovale and other cardiac defects
JP6173738B2 (ja) ポリマーテザーを用いる塞栓コイル切り離し機構
US20070239151A1 (en) Method and apparatus for the detachment of catheters or puncturing of membranes and intraluminal devices within the body
EP2939629B1 (fr) Appareil d'occlusion d'un vaisseau par embolisation rf
EP2644132A1 (fr) Mécanisme de détachement de spirale embolique avec élément distale flexible et élément de chauffage électrique résistif
US20120143187A1 (en) Devices and methods for tissue apposition
WO2021011502A1 (fr) Dispositif permettant un accès transseptal de gros diamètre et un nouvel accès auriculaire ultérieur et procédé associé
WO2017027726A1 (fr) Dispositif de suture et procédé d'utilisation
US20150066008A1 (en) Device for automatic anchor undeployment and retraction
WO2015118373A1 (fr) Dispositif pour le repliement et la rétraction automatiques d'une ancre
US20120277782A1 (en) Apparatus and method for enabling perforating vein ablation
WO2016086051A1 (fr) Systèmes et méthodes de contraception permanente pour la femme
US20120259346A1 (en) Thermal suture cutting device
RU2559018C2 (ru) Усовершенствованное лигирующее устройство для хирургического применения
KR102084856B1 (ko) 분리 길이의 조절이 가능한 색전술용 코일 구조체 및 이를 포함하는 색전술 시술장치
EP4161393A1 (fr) Dispositif permettant un accès transseptal de gros diamètre et un nouvel accès auriculaire ultérieur et procédé associé
US20210196368A1 (en) Electrosurgical system with tissue and maximum current identification
WO2016027489A1 (fr) Procédé d'éveinage d'un vaisseau sanguin et dispositif d'éveinage d'un vaisseau sanguin
GB2543083A (en) Apparatus and method for occluding a vessel
JP2016042989A (ja) 血管剥離デバイス
JP2016042990A (ja) 血管剥離デバイスおよび血管剥離方法
JPS622816B2 (fr)
IES84177Y1 (en) Surgical stapler

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 14833531

Country of ref document: EP

Kind code of ref document: A1

NENP Non-entry into the national phase

Ref country code: DE

REEP Request for entry into the european phase

Ref document number: 2014833531

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 2014833531

Country of ref document: EP