WO2015114656A3 - Mucoadhesive tablet of pregabalin - Google Patents

Mucoadhesive tablet of pregabalin Download PDF

Info

Publication number
WO2015114656A3
WO2015114656A3 PCT/IN2015/000033 IN2015000033W WO2015114656A3 WO 2015114656 A3 WO2015114656 A3 WO 2015114656A3 IN 2015000033 W IN2015000033 W IN 2015000033W WO 2015114656 A3 WO2015114656 A3 WO 2015114656A3
Authority
WO
WIPO (PCT)
Prior art keywords
mucoadhesive
pregabalin
mucoadhesive tablet
tablet
relates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IN2015/000033
Other languages
French (fr)
Other versions
WO2015114656A2 (en
Inventor
Nilesh Patel
Umesh Setty
Ashish Sehgal
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Intas Pharmaceuticals Ltd
Original Assignee
Intas Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intas Pharmaceuticals Ltd filed Critical Intas Pharmaceuticals Ltd
Publication of WO2015114656A2 publication Critical patent/WO2015114656A2/en
Publication of WO2015114656A3 publication Critical patent/WO2015114656A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0065—Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)

Abstract

The present invention relates to a mucoadhesive tablet comprising pregabalin with at least one mucoadhesive excipient, at least one swelling agent and at least one gelling agent, wherein the mucoadhesive tablet maintains gastric retention for the time period during which the drug is released into the stomach. Further it relates to a process for the preparation of the mucoadhesive tablet.
PCT/IN2015/000033 2014-01-22 2015-01-20 Mucoadhesive tablet of pregabalin Ceased WO2015114656A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN215/MUM/2014 2014-01-22
IN215MU2014 IN2014MU00215A (en) 2014-01-22 2015-01-20

Publications (2)

Publication Number Publication Date
WO2015114656A2 WO2015114656A2 (en) 2015-08-06
WO2015114656A3 true WO2015114656A3 (en) 2015-12-17

Family

ID=53757863

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2015/000033 Ceased WO2015114656A2 (en) 2014-01-22 2015-01-20 Mucoadhesive tablet of pregabalin

Country Status (2)

Country Link
IN (1) IN2014MU00215A (en)
WO (1) WO2015114656A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6919119B2 (en) * 2017-01-23 2021-08-18 日新製薬株式会社 A compressed solid pharmaceutical composition containing a γ-aminobutyric acid derivative substituted at the 3-position.
CN108159011A (en) * 2018-03-16 2018-06-15 中国药科大学 A kind of Pregabalin stomach retention sustained-release piece of biphasic controlled release and preparation method thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013054285A1 (en) * 2011-10-11 2013-04-18 Ranbaxy Laboratories Limited A gastroretentive dosage system and process of preparation thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013054285A1 (en) * 2011-10-11 2013-04-18 Ranbaxy Laboratories Limited A gastroretentive dosage system and process of preparation thereof

Also Published As

Publication number Publication date
WO2015114656A2 (en) 2015-08-06
IN2014MU00215A (en) 2015-08-28

Similar Documents

Publication Publication Date Title
IL256085B (en) A substituted derivative of cholanoic acid, a pharmaceutical composition comprising it and the substituted derivative for use in treatment
EP4349406A3 (en) Crystalline solid forms of 6-carboxy-2-(3,5-dichlorophenyl)-benzoxazole for use as a medicament
EP3102188A4 (en) Novel disintegration systems for pharmaceutical dosage forms
PH12016501841A1 (en) Immunosuppressant formulation
CA2863376A1 (en) Gastroretentive tablets
IL256299A (en) Immediate-release tablets containing a drug and processes for forming the tablets
WO2015191945A3 (en) Solid state forms of sofosbuvir
CA2863371A1 (en) Pregabalin gr tablets
EA202090913A1 (en) COMPOSITION OF MODIFIED RELEASE TABLETS CONTAINING MIRABEGRON
HK1223840A1 (en) A pharmaceutical composition containing combinations of nicotinamide and 5-aminosalicylic acid for beneficially influencing the intestinal microbiota and/or treating gastrointestinal inflammation
PH12016502272A1 (en) Ceritinib formulation
WO2015114656A3 (en) Mucoadhesive tablet of pregabalin
WO2016063289A3 (en) Pharmaceutical tablet compositions comprising rifaximin
WO2014125504A3 (en) Pharmaceutical compositions of febuxostat
IL250419A0 (en) Use in single pill/tablet/capsule of minocycline, fluconazole and atorvastatin in the treatment of multiple sclerosis
IL280389A (en) A substituted derivative of cholanoic acid, a pharmaceutical composition comprising it and the substituted derivative for use in treatment
WO2015166419A3 (en) Production method and sublingual pharmaceutical composition of ketorolac tromethamine and tramadol hydrochloride used for pain
WO2016020408A3 (en) Compounds for preventing ototoxicity
WO2015134603A3 (en) Methods for treating cancer
WO2015114655A3 (en) Modified release tablet of pregabalin
EP3250199A4 (en) A pharmaceutical composition for treating gastrointestinal diseases
WO2014122671A3 (en) Solid oral compositions of saxagliptin
WO2019221684A3 (en) The bilayer tablet formulation of fesoterodine
MX2015011152A (en) PHARMACEUTICAL COMPOSITION OF OMEPRAZOL-BICARBONATE SODIUM TO INTEGRATE A CAPSULE, FOR THE TREATMENT OF ALOPATHY RELATED TO GASTRIC ACIDITY.
EP3666264C0 (en) Biodegradable covalent matrices for the oral delivery of insulin directed to the colon, activated by microbiota, and production method thereof

Legal Events

Date Code Title Description
NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 15743837

Country of ref document: EP

Kind code of ref document: A2