WO2015087343A3 - An improved process for the preparation of nilotinib and pharmaceutically acceptable salts thereof - Google Patents
An improved process for the preparation of nilotinib and pharmaceutically acceptable salts thereof Download PDFInfo
- Publication number
- WO2015087343A3 WO2015087343A3 PCT/IN2014/000754 IN2014000754W WO2015087343A3 WO 2015087343 A3 WO2015087343 A3 WO 2015087343A3 IN 2014000754 W IN2014000754 W IN 2014000754W WO 2015087343 A3 WO2015087343 A3 WO 2015087343A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- nilotinib
- preparation
- pharmaceutically acceptable
- acceptable salts
- improved process
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Abstract
The present invention relates to an improved process for the preparation of nilotinib and pharmaceutically acceptable salts thereof, with high purity and yields.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN5653/CHE/2013 | 2013-12-09 | ||
IN5653CH2013 IN2013CH05653A (en) | 2013-12-09 | 2014-12-08 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2015087343A2 WO2015087343A2 (en) | 2015-06-18 |
WO2015087343A3 true WO2015087343A3 (en) | 2015-08-27 |
Family
ID=53371924
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/IN2014/000754 WO2015087343A2 (en) | 2013-12-09 | 2014-12-08 | An improved process for the preparation of nilotinib and pharmaceutically acceptable salts thereof |
Country Status (2)
Country | Link |
---|---|
IN (1) | IN2013CH05653A (en) |
WO (1) | WO2015087343A2 (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3404025B1 (en) * | 2017-05-16 | 2019-12-04 | F.I.S.- Fabbrica Italiana Sintetici S.p.A. | Process for the preparation of pure nilotinib and its salt |
SG10201909596RA (en) * | 2019-10-14 | 2021-05-28 | Esco Aster Pte Ltd | Synthesis of Tyrosine Kinase Inhibitors |
CN112745300A (en) * | 2021-01-21 | 2021-05-04 | 杭州浙中医药科技有限公司 | Method for preparing N- (5-carboxyl-2-methylphenyl) -4- (3-pyridine) -2-pyrimidinamine |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010009402A2 (en) * | 2008-07-17 | 2010-01-21 | Teva Pharmaceutical Industries Ltd. | Nilotinib intermediates and preparation thereof |
CN103288804A (en) * | 2013-05-24 | 2013-09-11 | 苏州明锐医药科技有限公司 | Preparation method of nilotinib |
-
2014
- 2014-12-08 WO PCT/IN2014/000754 patent/WO2015087343A2/en active Application Filing
- 2014-12-08 IN IN5653CH2013 patent/IN2013CH05653A/en unknown
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010009402A2 (en) * | 2008-07-17 | 2010-01-21 | Teva Pharmaceutical Industries Ltd. | Nilotinib intermediates and preparation thereof |
CN103288804A (en) * | 2013-05-24 | 2013-09-11 | 苏州明锐医药科技有限公司 | Preparation method of nilotinib |
Also Published As
Publication number | Publication date |
---|---|
IN2013CH05653A (en) | 2016-06-24 |
WO2015087343A2 (en) | 2015-06-18 |
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