WO2015047413A1 - Procédés et suppléments alimentaires pour bétail - Google Patents

Procédés et suppléments alimentaires pour bétail Download PDF

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Publication number
WO2015047413A1
WO2015047413A1 PCT/US2013/062709 US2013062709W WO2015047413A1 WO 2015047413 A1 WO2015047413 A1 WO 2015047413A1 US 2013062709 W US2013062709 W US 2013062709W WO 2015047413 A1 WO2015047413 A1 WO 2015047413A1
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Prior art keywords
vitamin
ppm
supplement
feed
combinations
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PCT/US2013/062709
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English (en)
Inventor
Fredrik B. SANDBERG
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Furst-Mcness Company
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Publication of WO2015047413A1 publication Critical patent/WO2015047413A1/fr
Priority to US15/085,601 priority Critical patent/US20160206654A1/en

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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/174—Vitamins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/142—Amino acids; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/20—Inorganic substances, e.g. oligoelements
    • A23K20/30—Oligoelements
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/10—Feeding-stuffs specially adapted for particular animals for ruminants
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/15—Vitamins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/15—Vitamins
    • A23L33/155—Vitamins A or D
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/16—Inorganic salts, minerals or trace elements
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Definitions

  • a lactating pig may require a different supplement than a pig that is being prepared for slaughter.
  • Weaning and growing pigs use a majority of the food they intake for growth and maintenance. As pigs mature, a pig's food intake is used primarily for maintenance and reproduction (Sandberg, et al., Br. J. Nutr., 2005, 93:205-212; Sandberg, et al., Br. J. Nutr., 2005, 93:213-224). Digested food that is not used for maintenance or reproduction gets stored in the pig as fat.
  • additives and nutritional supplements are described in the art for modifying the nutritional and metabolic status of pigs and other livestock.
  • Such additives include nutritional supplements (e.g., vitamins, minerals, and protein supplements), as well as pharmacologic actives (e.g., chemo therapeutics such as beta agonists, and antibiotics).
  • pharmacologic actives may be effective to improve the health and metabolism of animals, their use may present regulatory, consumer and welfare concerns. Accordingly, there remains a need to develop feed supplements that increase a pig's feed intake and growth rate, especially during finishing.
  • compositions that are suitable as animal feed or animal feed supplements for consumption by livestock, such as pigs.
  • the composition is a feed supplement, comprising a botanical component, such as an essential oil from an herb or spice, selected from the group consisting of cinnamon, oregano, chili, turmeric, extracts thereof, and combinations thereof.
  • the compositions also contain one or more of zinc, copper, chromium, and vitamin B.
  • the zinc may be a zinc methionine complex
  • the copper may be copper chloride
  • the chromium may be chromium tripicolinate
  • the vitamin B may be vitamin B 12 .
  • the present technology further provides methods for improving the nutritional status of a livestock animal, such as increasing the lean muscle mass.
  • Such methods include feeding a livestock animal a food composition comprising a botanical component comprising cinnamaldehyde, carnosic acid, rosmarinic acid, carvacrol, thymol, capsaicin and curcumin; and a nutritional supplement selected from the group consisting of zinc, copper, chromium, vitamin B, and combinations thereof.
  • the cinnamaldehyde, carnosic acid, rosmarinic acid, carvacrol, thymol, capsaicin and curcumin can be added in purified forms, or as cinnamon, rosemary, oregano, chili peppers, turmeric, or extracts thereof.
  • the food composition to be fed to the livestock can further comprise vitamin A, vitamin D, and vitamin E. Feeding the food composition can be performed from livestock weaning to finishing, or only during finishing.
  • compositions suitable for use as feed supplements comprise a combination of ingredients that support and promote feed intake in livestock.
  • livestock includes any animal kept for commercial useful purposes, such as domesticated animals that are raised for producing commodities such as food (e.g., milk and meat), animal products (e.g., fiber), or working in an agricultural or other commercial activity.
  • Livestock include pigs, cows, horses, sheep, chickens and goats.
  • the livestock animal is a pig.
  • the composition is an animal feed, which is intended to provide essentially all nutritional needs of a livestock animal.
  • animal feed compositions comprise a bulk food material, which supplies the animal with energy, protein, amino acids, fat as well as vitamins and minerals, and a feed supplement, as described further herein.
  • the compositions of the present technology provide a diet with ingredients that increase feed intake and promote efficient partitioning of nutrients. For example, the combination of these modes of action can support faster growth rates and greater rates of lean (as well as fat) deposition in late finishing.
  • the compositions support enhanced carcass quality by increasing loin depth and carcass yield, and may reduce variation in weight of carcasses at marketing.
  • compositions are especially useful for increasing the growth rate of pigs with a body weight from about 200 pounds until the pig weighs from about 250 pounds to about 300 pounds, or until the pig is otherwise ready for slaughter. Although many benefits can be obtained by feeding the compositions to livestock for finishing, the compositions can be used at all stages of production from weaning to market.
  • the present technology provides compositions that improve the general health and nutritional status of livestock, such as pigs. It has been found that livestock animals that are disease challenged, such as having inflammation, will partition nutrients away from maintenance and growth, towards support of immune functions and repair of damaged tissues (Sandberg, et al., J. Anim. Set, 2006, 84: 1552-1566; Sandberg, et al., Br. J. Nutr., 2005, 93:205-212; Sandberg, et al., Animal, 2007, 1:67-86). Partitioning nutrients away from maintenance and growth causes a reduced efficiency in converting feed into meat (Sandberg, et al., Br. J.
  • compositions of the present technology support the livestock animal's natural desire to grow as efficiently and as quickly as possible to attain its final degree of maturity.
  • compositions of the present invention comprise two or more components (e.g., two or more botanical components, two or more nutritional components, or a combination of botanical components and nutritional components) that afford synergistic benefits in the feeding of animals, present at synergistic levels.
  • components e.g., two or more botanical components, two or more nutritional components, or a combination of botanical components and nutritional components
  • synergistic combinations comprise components at levels that, when fed to an animal, afford a nutritional benefit greater than the additive effect of feeding each component individually.
  • compositions of the current technology comprise one or more essential oils, oleoresins or other botanical components.
  • the compositions comprise botanical components in the form of herbs, spices, essential oils or other extracts thereof, and combinations thereof.
  • Botanical components among those useful herein are selected from the group consisting of cinnamon, oregano, rosemary, sage, chili, turmeric, extracts thereof, and combinations thereof. These herbs and spices are rich in various components useful in the present compositions. For example, cinnamon is rich in cinnamaldehyde; oregano is rich in carvacrol and thymol; rosemary and sage are rich in carnosic acid and rosmarinic acid; chili is rich in capsaicin; and turmeric is rich in curcumin.
  • the composition can comprise the active ingredients from the herbs and spices, including cinnamaldehyde, carnosic acid, rosmarinic acid, carvacrol, thymol, capsaicin, curcumin, and combinations thereof.
  • active ingredients from the herbs and spices including cinnamaldehyde, carnosic acid, rosmarinic acid, carvacrol, thymol, capsaicin, curcumin, and combinations thereof.
  • Such extracts and compounds may be isolated from natural sources using methods among those known in the art (Douglas, et al., Herbs, spices and essential oils. UNIDO and FAO 2005).
  • the present compositions may contain cinnamon, a cinnamon essential oil, cinnamaldehyde, or combinations thereof.
  • Cinnamon essential oil may be obtained from the bark of cinnamon trees, of the genus Cinnamomum, by methods among those known in the art.
  • Cinnamaldehyde may be made synthetically, or by extraction from cinnamon bark, such as by steam distillation.
  • Oregano essential oil may be made from the leaves and flowers of the herb, Origanium vulgare.
  • the oregano oil may comprise carvacrol and thymol.
  • carvacrol and thymol can be synthetically produced.
  • Rosemary oil may be extracted from Rosmarinus officinalis, and may be a source of rosmarinic acid, carnosic acid, or both in the nutritional compositions (Windisch, et al., J. Anim. Set, 2008, E: 140- 148).
  • rosmarinic acid may be extracted from culinary herbs such as Ocimum basilicum (basil), Ocimum tenuiflorum (holy basil), Melissa officinalis (lemon balm), Origanum majorana (marjoram), Salvia officinalis (sage), thyme and peppermint, and Prunella vulgarism, Heliotropium foertherianum, Maranta leuconeura, Maranta depressa, Thalia geniculate, and Anthoceros agrestis.
  • culinary herbs such as Ocimum basilicum (basil), Ocimum tenuiflorum (holy basil), Melissa officinalis (lemon balm), Origanum majorana (marjoram), Salvia officinalis (sage), thyme and peppermint, and Prunella vulgarism, Heliotropium foertherianum, Maranta leuconeura, Maranta depressa, Thalia geniculate, and Anthoceros agrestis.
  • chili extract containing capsaicin may be obtained from chili peppers of the genus Capsicum.
  • turmeric extract, containing curcumin may be obtained from the leaves of the herb Curcuma longa.
  • the capsaicin and curcumin can be individually synthetically produced.
  • compositions of the present technology may stimulate gastric secretions that support increased feed intake, or increase blood flow through vasodilator mechanisms, supporting an increased rate of heat loss from the body.
  • cinnamaldehyde may have antimicrobial properties (Burt, Int. J. Food Micro., 2004, 94:223-253; Si, et al., J. App. Micro., 2006, 100:296-305), especially with respect to oral bacteria, is a fungicide, is an anti-cancer agent, and stimulates growth (Lee, Essential oils in broiler nutrition. Dissertation, University of Utrecht, The Netherlands. 2002. (ISBN Number: 90-393-3222-3)).
  • Carnosic acid is a potent antioxidant, and may protect skin cells against UV radiation, afford antiinflammatory properties, and provide protection against carcinogens.
  • Rosmarinic acid is an anxiolytic (inhibits anxiety), antioxidant, and may inhibit Japanese encephalitis (common in pigs), and afford anti-microbial and antioxidant properties (Windisch, et al., J. Anim. Set, 2008, E: 140-148). Rosmarinic acid may also provide anti-cancer properties, slowing or preventing metastasis by inhibiting matrix metallopeptidase 13 (MMP-13) and having an antiproliferative effect on tumor cells by inhibiting Indoleamine-pyrrole 2,3- dioxygenase (IDO), which is an enzyme that prevents the immune system from targeting tumor cells. Inhibiting IDO may also reduce proinflammatory cytokine activity.
  • MMP-13 matrix metallopeptidase 13
  • IDO Indoleamine-pyrrole 2,3- dioxygenase
  • Carvacrol may inhibit the growth of bacteria (Burt, Int. J. Food Micro., 2004, 94:223-253; Si, et al., J. App. Micro., 2006, 100:296-305), including Escherichia coli, Bacillus cereus, Staphylococcus aureus, Salmonella typhimurium, and Pseudomonas aeruginosa.
  • bacteria Bacillus cereus, Staphylococcus aureus, Salmonella typhimurium, and Pseudomonas aeruginosa.
  • COX-2 prostaglandin-endoperoxide synthase 2
  • Carvacrol has also been shown to improve feed conversion in animals (Lee, Essential oils in broiler nutrition.
  • Thymol may provide antimicrobial properties, inhibiting bacterial growth, including Aeromoans hydrophila and Staphylococcus aureus, and act as a natural fungicide (Windisch, et al., J. Anim. Set, 2008, E: 140- 148). Thymol, may also stimulate growth (Lee, Essential oils in broiler nutrition. Dissertation, University of Utrecht, The Netherlands. 2002. (ISBN Number: 90-393-3222-3)), and protect against ringworm and hookworm infections (Burt, Int. J. Food Micro., 2004, 94:223-253; Si, et al., J.
  • Capsaicin may act as an analgesic and a vasodilator, and may have the ability to kill various types of cancer cells by causing apoptosis, and promotes heat loss from the body. Capsaicin also promotes digestion (Lee, Essential oils in broiler nutrition. Dissertation, University of Utrecht, The Netherlands. 2002. (ISBN Number: 90-393-3222-3)). Curcumin may provide antioxidant properties, preventing the growth of various tumors, and boosting the immune system by suppressing the activity of pro-inflammatory mediators.
  • Curcumin may also protect against skin diseases, colitis, viruses, and stomach ulcers, stimulates gastric secretions, and promotes digestion (Lee, Essential oils in broiler nutrition. Dissertation, University of Utrecht, The Netherlands. 2002. (ISBN Number: 90- 393-3222-3)). Curcumin may also assist in the maintenance of normal cholesterol levels.
  • Nutritional Components Vitamins and Minerals
  • compositions of the present technology further comprise one or more vitamins and minerals.
  • the compositions comprise a mineral selected from the group consisting of zinc, copper, chromium, calcium, iron, iodine, magnesium, potassium, sodium, selenium, manganese, molybdenum, and mixtures thereof,
  • the compositions comprise a mineral selected from the group consisting of zinc, copper, chromium, and combinations thereof.
  • compositions comprise such minerals in a bioavailable form, such as in a nutritionally-acceptable salt or other compound.
  • a "nutritionally- acceptable” compound provides a nutritional benefit, without undue adverse side effects (such as toxicity, irritation, or allergic response), commensurate with a reasonable benefit/risk ratio when used in the manner of this technology.
  • the compositions of the present technology may- comprise a zinc methionine complex, copper chloride, and chromium tripicolinate.
  • a zinc methionine complex, and tri-basic copper chloride may increase growth rates supplementing the livestock with highly digestible forms of the essential nutrients, zinc and copper.
  • Chromium tripicolinate may help the livestock maintain the natural function of the insulin- IGF- 1 growth hormone axis supporting increased deposition of nutrients as body lean and fat,
  • compositions of the present technology also comprise a vitamin, selected from the group consisting of vitamin A, vitamin B, vitamin D, vitamin E, vitamin K and combinations thereof.
  • the vitamin A can be in the form of retinol, retinyl acetate, palmitate, alpha-carotene, beta-carotene, gamma-carotene, beta-cryptoxanthin, or combinations thereof.
  • the vitamin B can be vitamin Bi (thiamine, or thiamine mononitrate), vitamin B 2 (riboflavin), vitamin B 3 (niacin, or niacinamide), vitamin B5 (pantothenic acid, or calcium pantothenate), vitamin B 6 (pyridoxine, pyridoxine hydrochloride, pyridoxal, pyridoxamine, or pyridoxine hydrochloride), vitamin B 7 (biotin or d-biotin), vitamin B 9 (folic acid), vitamin B 12 (cobalamins or cyanocobalamin), or combinations thereof.
  • vitamin Bi thiamine, or thiamine mononitrate
  • vitamin B 2 riboflavin
  • vitamin B 3 niacin, or niacinamide
  • vitamin B5 pantothenic acid, or calcium pantothenate
  • vitamin B 6 pyridoxine, pyridoxine hydrochloride, pyridoxal, pyridoxamine, or pyridoxine hydrochloride
  • the vitamin D can be in the form of vitamin Di (molecular compound of ergocalciferol with lumisterol, 1 : 1), vitamin D 2 (ergocalciferol), vitamin D 3 (cholecalciferol), vitamin D 4 (22-dihdroergocalciferol), vitamin D5 (sitocalciferol), or combinations thereof.
  • vitamin Di molecular compound of ergocalciferol with lumisterol, 1 : 1
  • vitamin D 2 ergocalciferol
  • vitamin D 3 cholecalciferol
  • vitamin D 4 22-dihdroergocalciferol
  • vitamin D5 sitocalciferol
  • the composition includes tocopherols, such as alpha-tocopherol (vitamin E), beta-tocopherol, gamma-tocopherol, delta- tocopherol; tocotrienols (also referred to as "tocols"), such as alpha-tocotrienol, beta- tocotrienol, gamma-tocotrienol, delta-tocotrienol; or combinations thereof.
  • the vitamin K can be vitamin K 3 (menadione dimethylpyrimidinol bisulfite).
  • compositions comprise vitamin B.
  • compositions may comprise vitamin A, vitamin D, vitamin E, vitamin B 12 , riboflavin, niacin, calcium pantothenate, menadione dimethylpyrimidinol bisulfite, folic acid, pyridoxine hydrochloride, thiamine mononitrate, and d-biotin.
  • compositions provide high levels of vitamin A and D to support optimum growth, and a combination of B-vitamins to support metabolism and muscle deposition.
  • compositions of the present technology may comprise optional components, including additional nutritional components (such as amino acids), absorption enhancing components, digestive aids (such as enzymes and probiotics), flavorants (artificial and natural flavor components), preservatives, and formulation aids.
  • additional nutritional components such as amino acids
  • absorption enhancing components such as absorption enhancing components
  • digestive aids such as enzymes and probiotics
  • flavorants artificial and natural flavor components
  • compositions of the present technology may optionally comprise probiotic bacteria.
  • probiotic bacteria include Bacillus Subtilis and Bacillus Lichenformis. Both of these bacteria secrete enzymes that breakdown fibrous materials in the gastrointestinal tract of livestock. The activity of the bacteria continues after excretion in the feces, breaking down materials on slats, in pits or in lagoons.
  • the probiotic bacteria also reduce gaseous ammonia excretions by at least about 30% and hydrogen sulfide excretions by at least about 15% by reducing fermentation activity in the hindgut of livestock.
  • Plant substrates are composed of multiple fractions of starch, fibers, and non-starch polysaccharides, as well as proteins.
  • feed ingredients are digested more efficiently.
  • feed ingredients By digesting feed ingredients more efficiently (for example, in pigs of all degrees of maturity, including weaned pigs to finishing pigs to sows), the energy value of the feed consumed is increased.
  • Animals that can digest their feed more effectively may also have higher rate of passage of feed through the gastrointestinal tract, leading to a higher rate of feed intake, even whilst consuming diets relatively high in fibrous materials.
  • compositions can be added to the composition to provide supplemented feed suitable for lactating livestock to support the essential amino acid and energy requirements of, for example, high producing sows, specifically for first and second parity sows, to maximize life time performance, by preventing excessive weight loss during lactations. Therefore, in various embodiments, the present technology provides for the addition of extruded soybean meal, which is a source of highly digestible protein and fat, and soybean meal, which is a source of highly digestible protein.
  • the compositions may also comprise coconut oil, dried whey solids, dried whey protein concentrate, soy lecithin, and cereal food fines.
  • coconut oil is a source of digestible protein
  • dried whey protein concentrate is a source of digestible protein
  • soy lecithin aids in the digestion of fats by breaking down larger fat globules into smaller fat globules
  • cereal food fines are a source of multiple sugars.
  • the amino acids L- valine, Dl- methionine supplement, L-threonine, L-lysine monohydrochloride, and tryptophan can be added to complete a highly specific amino acid balance of the composition. A correct balance of amino acids is particularly important for livestock during lactation, especially for sows.
  • compositions of the present technology comprise one or more botanical components (e.g., herbs, spices, essential oils, and oleoresins), at nutritionally- acceptable levels.
  • botanical components e.g., herbs, spices, essential oils, and oleoresins
  • Exemplary levels of components are set forth in the following table, in reference to a feed supplement composition of the present technology.
  • Zinc from about 5,000 ppm to about 20,000 ppm
  • Vitamin B 12 from about 200 meg/pound to about 800 meg/pound from about 300 meg/pound to about 600 meg/pound about 500 meg/pound
  • Riboflavin from about 30 ppm to about 500 ppm
  • Niacin from about 200 ppm to about 5000 ppm
  • d-Panothenic Acid from about 100 ppm to about 2000 ppm
  • Vitamin A from about 50,000 IU/lb to about 500,000 IU/lb
  • Vitamin D from about 1000 IU/lb to about 100,000 IU/lb
  • Vitamin E from about 100 IU/lb to about 10,000 IU/lb
  • the feed composition comprises a botanical component:nutritional component ratio of from about 1:50 to about 90: 1.
  • the botanical component:nutritional component ratio can be about 1:50, about 2:50 (about 1:25), about 5:50 (about 1: 10), about 10:50 (about 1:5), about 15:50 (about 3: 10), about 20:50 (about 2:5), about 25:50 (about 1:2), about 30:50 (about 3:5), about 35:50 (about 7: 10), about 40:50 (about 4:5), about 45:50 (about 9: 10), about 50:50 (about 1: 1), about 2: 1, about 4: 1, about 6: 1, about 8: 1, about 10: 1, about 12: 1, about 14: 1, about 16: 1, about 18: 1, about 20: 1, about 30: 1, about 40: 1, about 50: 1, about 60: 1, about 70: 1, about 80: 1, or about 90: 1.
  • the feed supplement of the present technology comprises a carrier, to facilitate mixing with a base feed composition and effective delivery to the livestock animal.
  • a carrier comprises finely ground distillers dried grains with solubles (DDGS), rice hulls, calcium carbonate, and combinations thereof.
  • DDGS is commercially available, such as SOLULAC ® , sold by Grain Processing Corp., Muscatine, Iowa.
  • the feed supplements may optionally comprise mineral oil and/or vegetable or animal derived oils for fat soluble ingredients, as a feed additive and to reduce dustiness.
  • compositions consist essentially of one or more botanical components (or herbs or spices containing such essential oils or oleoresins), vitamins, minerals, and one or more optional ingredients as described above.
  • compositions of the present technology may optionally comprise antibiotics or other chemotherapeutic actives.
  • the compositions do not comprise antibiotics or other chemotherapeutic agents, such as ractopamine.
  • the compositions are essentially free, or do not contain, carnitine.
  • the level of carnitine in some compositions is less than about 5 ppm, preferably less than 1 ppm.
  • the present technology also provides animal food compositions comprising a bulk feed material and a feed supplement of the present technology.
  • Bulk food material useful in this technology includes materials known in the art for feeding to livestock.
  • the bulk food material may contain grains, such as corn, sorghum, wheat, rye, triticale, oats, barley and combinations thereof.
  • Feed compositions may comprise a bulk feed material and a feed supplement of the present technology, at levels of from about 0.5 to about 15, from about 1 to about 10, or from about 2 to about 7 pounds of the feed supplement per ton of feed composition.
  • the present technology further relates to methods for improving the nutritional status of a livestock animal, such as a pig, by feeding a composition of the present technology to the livestock animal.
  • Methods provided by the present technology include methods for increasing the lean muscle mass of livestock, methods for improving livestock yield, methods of improving parity, methods for improving heat tolerance, methods for reducing still-born livestock, methods for improving food intake, methods for increasing lactation, methods for increasing livestock longevity.
  • Such methods comprise feeding to the livestock animal a nutritionally effective amount of a composition of the present technology.
  • the present technology also provides methods for managing the nutritional status of a group of livestock animals, such as pigs, by feeding the animals a composition of the present technology.
  • Such methods include methods for improving livestock yield, methods for improving food intake, methods for improving feeding efficiency, and methods for reducing livestock death.
  • Methods also include methods for increasing total yield of full value pigs. Value may be determined by achieving high premiums according to packer matrices.
  • the present technology provides methods for improving the nutritional status of a livestock animal comprising feeding the animal a feed supplement, or an animal feed comprising a feed supplement, comprising cinnamaldehyde, carnosic acid, rosmarinic acid, carvacrol, thymol, capsaicin, curcumin, and combinations thereof; and a nutritional component selected from the group consisting of zinc, copper, chromium, vitamin B, and combinations thereof.
  • the botanical component comprises a mixture of cinnamaldehyde, carnosic acid, rosmarinic acid, carvacrol, thymol, capsaicin, curcumin.
  • the cinnamaldehyde, carnosic acid, rosmarinic acid, carvacrol, thymol, capsaicin and curcumin can be added in purified forms, or as cinnamon, rosemary, oregano, chili peppers, turmeric, extracts thereof, or combinations thereof.
  • the food composition to be fed to the livestock can further comprise vitamin A, vitamin D, and vitamin E. Additionally, the food composition can include the various optional components described above.
  • Feeding the feed supplement can be performed from livestock weaning to finishing, or only during finishing.
  • the food composition can be fed to pigs from weaning, until time for slaughter.
  • the feed supplement is fed to pigs from when the pig has a body weight of about 200 pounds until time for slaughter.
  • the feed supplement may also be fed to lactating sows.
  • feeding a feed supplement of the current technology increases the feed intake of the livestock by from about 2% to about 20%, relative to the same livestock eating a bulk food material feed without the feed supplement.
  • feeding the feed supplement increases the feed intake of livestock by from about 8% to about 12%.
  • the feed intake is increased by from about 5% to about 15%, or from about 6% to about 10%, or from about 8% to about 12%.
  • feeding the feed supplement to livestock may increase the growth rate of the livestock by from about 2% to about 20%, relative to the same livestock eating a bulk food material without the feed supplement.
  • feeding the feed supplement increases the growth rate of livestock by from about 8% to about 12%.
  • feeding the feed supplement of the present technology to livestock provides further benefits including improving feed efficiency by from about 0.5% to about 5%, by from about 1% to about 3%.
  • Feeding the feed supplement to livestock may also increase loin depth by from about 0.1 to about 0.3 inches, or by from about 3% to about 10%.
  • Feeding the feed supplement to livestock may increase fat depth by from about 0.05 inches to about 0.1 inches, or by from about 7% to about 14%.
  • feeding the feed supplement to livestock may increase the percent lean by from about 0.5% to about 0.75%, and the yield by from about 0.5% to about 1.0%.
  • Feeding the feed supplement may increases total percentile of full value pigs that achieve the highest premiums according to packer matrixes by from about 3% to about 4%. Feeding the feed supplement to livestock may also reduce the number of dead, diseased or disabled animals by from about 0.05% to about 1.0%.
  • An exemplary feed supplement of the present technology is made by weighing an amount of the following components: cinnamon, oregano, chili, turmeric, zinc methionine complex, copper chloride, chromium tripicolinate, vitamin B 12 supplement, vitamin A supplement, vitamin D supplement, vitamin E supplement, riboflavin supplement, niacin supplement, calcium pantothenate, menadione dimethylpyrmidinol bisulfite, folic acid, pyridoxine hydrochloride, thiamine mononitrate, d-biotin, mineral oil, and natural and artificial flavors.
  • the components are placed in a mixer along with a carrier comprising DDGS, rice hulls and calcium carbonate.
  • the components and carrier are mixed for about 1 minute to provide a mixture.
  • Mineral oil is added to the mixture and it is mixed for a further 6 minutes to generate the feed supplement.
  • the feed supplement is then packaged in bags.
  • composition has the following nutritional profile.
  • Vitamin A 200,000 IU/LB
  • Vitamin D 18,000 IU/LB
  • Vitamin B 12 480 mcg/lb
  • the feed supplement is removed from a bag and admixed with a bulk feed material so that 5 pounds of the composition are mixed with one ton of the bulk feed material.
  • the resulting animal feed composition is fed to pigs weighing approximately 200 pounds, daily, until the animals reach a weight of from about 260 to about 290 pounds.
  • the animals are found to have increased feed intake of from 8% to 12%, increased growth rate of from 8% to 12%, slightly increased feed efficiency (up to 3%), increased loin depth of from 0.1 to 0.3 inches (3% to 10%), increased fat depth of from 0.05 to 0.1 inches (7% to 14%), increased percent lean of 0.5 to 0.75% points, increased yield of from 0.5 to 1 % points, and increased total percentage of full value pigs achieving the highest premiums according to packer matrices by 3 to 4% points. In addition the number of sick or dead pigs is reduced by 0.5 to 1%.
  • the words “prefer” or “preferable” refer to embodiments of the technology that afford certain benefits, under certain circumstances. However, other embodiments may also be preferred, under the same or other circumstances. Furthermore, the recitation of one or more preferred embodiments does not imply that other embodiments are not useful, and is not intended to exclude other embodiments from the scope of the technology.
  • the word "include,” and its variants, is intended to be non-limiting, such that recitation of items in a list is not to the exclusion of other like items that may also be useful in the materials, compositions, devices, and methods of this technology.
  • the terms “can” and “may” and their variants are intended to be non-limiting, such that recitation that an embodiment can or may comprise certain elements or features does not exclude other embodiments of the present technology that do not contain those elements or features.
  • compositions or processes specifically envisions embodiments consisting of, and consisting essentially of, A, B and C, excluding an element D that may be recited in the art, even though element D is not explicitly described as being excluded herein.
  • element D is not explicitly described as being excluded herein.
  • the term "consisting essentially of recited materials or components envisions embodiments "consisting of the recited materials or components.
  • A" and “an” as used herein indicate “at least one” of the item is present; a plurality of such items may be present, when possible.
  • “About” when applied to values indicates that the calculation or the measurement allows some slight imprecision in the value (with some approach to exactness in the value; approximately or reasonably close to the value; nearly). If, for some reason, the imprecision provided by “about” is not otherwise understood in the art with this ordinary meaning, then “about” as used herein indicates at least variations that may arise from ordinary methods of measuring or using such parameters.
  • ranges are, unless specified otherwise, inclusive of endpoints and include disclosure of all distinct values and further divided ranges within the entire range.
  • a range of “from A to B” or “from about A to about B” is inclusive of A and of B.
  • the phrase “from about A to about B” includes variations in the values of A and B, which may be slightly less than A and slightly greater than B; the phrase may be read be "about A, from A to B, and about B.” Disclosure of values and ranges of values for specific parameters (such as temperatures, molecular weights, weight percentages, etc.) are not exclusive of other values and ranges of values useful herein.
  • two or more specific exemplified values for a given parameter may define endpoints for a range of values that may be claimed for the parameter.
  • Parameter X is exemplified herein to have value A and also exemplified to have value Z
  • Parameter X may have a range of values from about A to about Z.
  • disclosure of two or more ranges of values for a parameter (whether such ranges are nested, overlapping or distinct) subsume all possible combination of ranges for the value that might be claimed using endpoints of the disclosed ranges.
  • Parameter X is exemplified herein to have values in the range of 1-10, or 2-9, or 3-8, it is also envisioned that Parameter X may have other ranges of values including 1-9, 1-8, 1-3, 1-2, 2-10, 2-8, 2-3, 3-10, and 3-9.

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  • Chemical & Material Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Animal Husbandry (AREA)
  • Mycology (AREA)
  • Health & Medical Sciences (AREA)
  • Nutrition Science (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
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Abstract

L'invention concerne un supplément alimentaire contenant un composant botanique et un composant nutritionnel. Le composant botanique comprend du cinnamaldéhyde, de l'acide carnosique, de l'acide rosmarinique, du carvacrol, du thymol, de la capsaïcine et de la curcumine. Le composant nutritionnel comprend du zinc, du cuivre, du chrome et de la vitamine B. L'invention concerne également un procédé d'amélioration de l'état nutritionnel, par exemple d'augmentation de la masse musculaire maigre, de cochons ou autres animaux d'élevage. Le procédé consiste à alimenter le bétail avec une composition contenant un composant botanique comprenant du cinnamaldéhyde, de l'acide carnosique, de l'acide rosmarinique, du carvacrol, du thymol, de la capsaïcine et de la curcumine ; et un composant nutritionnel comprenant du zinc, du cuivre, du chrome et de la vitamine B.
PCT/US2013/062709 2013-09-30 2013-09-30 Procédés et suppléments alimentaires pour bétail WO2015047413A1 (fr)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016187422A1 (fr) * 2015-05-19 2016-11-24 Ralco Nutrition, Inc. Compositions d'huiles essentielles et applications utilisant des huiles essentielles
WO2018146643A1 (fr) * 2017-02-13 2018-08-16 Evolva Sa Compléments naturels destinés à améliorer la santé et les performances d'animaux
WO2020201586A1 (fr) * 2019-04-01 2020-10-08 Lipidos Toledo S.A. Supplément destiné à être utilisé dans l'alimentation pour animaux

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010016580A1 (en) * 1998-08-28 2001-08-23 Harpe Jon De La Chromium picolinate compositions
US20100303951A1 (en) * 2009-05-28 2010-12-02 Gregory Dean Sunvold Delivering an Active Ingredient in Pet Food
US20110021461A1 (en) * 2008-01-04 2011-01-27 Novus International Inc. Combinations to improve animal health and performance
US20110287109A1 (en) * 2010-05-24 2011-11-24 Max International, Llc Compositions And Beverages Comprising Nutrients, Vitamins, Sugars, Cysteine, And/Or Sugar-Cysteine Products

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010016580A1 (en) * 1998-08-28 2001-08-23 Harpe Jon De La Chromium picolinate compositions
US20110021461A1 (en) * 2008-01-04 2011-01-27 Novus International Inc. Combinations to improve animal health and performance
US20100303951A1 (en) * 2009-05-28 2010-12-02 Gregory Dean Sunvold Delivering an Active Ingredient in Pet Food
US20110287109A1 (en) * 2010-05-24 2011-11-24 Max International, Llc Compositions And Beverages Comprising Nutrients, Vitamins, Sugars, Cysteine, And/Or Sugar-Cysteine Products

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016187422A1 (fr) * 2015-05-19 2016-11-24 Ralco Nutrition, Inc. Compositions d'huiles essentielles et applications utilisant des huiles essentielles
CN107846932A (zh) * 2015-05-19 2018-03-27 拉尔科营养品有限公司 精油组合物和利用精油的应用
US10342839B2 (en) 2015-05-19 2019-07-09 Ralco Nutrition, Inc. Essential oil compositions and applications utilizing essential oils
AU2016264468B2 (en) * 2015-05-19 2021-03-25 Ralco Nutrition, Inc. Essential oil compositions and applications utilizing essential oils
WO2018146643A1 (fr) * 2017-02-13 2018-08-16 Evolva Sa Compléments naturels destinés à améliorer la santé et les performances d'animaux
WO2020201586A1 (fr) * 2019-04-01 2020-10-08 Lipidos Toledo S.A. Supplément destiné à être utilisé dans l'alimentation pour animaux

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