WO2014203761A1

WO2014203761A1 - Mixing vessel and analysis device using same

Info

Publication number: WO2014203761A1
Application number: PCT/JP2014/065281
Authority: WO
Inventors: 石黒　浩二; 秀俊諸熊
Original assignee: 株式会社日立ハイテクノロジーズ
Priority date: 2013-06-20
Filing date: 2014-06-10
Publication date: 2014-12-24
Also published as: JPWO2014203761A1

Abstract

Provided is a vessel with which two or more kinds of liquid, powdered or granular samples can be mixed safely, easily, quickly, and reliably without contamination and the mixed sample can be easily removed. The mixing vessel is characterized in: being formed from two or more parts and having spaces in two or more chambers for storing the two or more kinds of samples; and two parts being configured so as to be capable of sliding in the axial direction and of achieving, as a result of a change in the relative position of the two parts, a state in which the two or more kinds of different samples are stored separately and a state in which the two or more kinds of different samples that have been stored are mixed.

Description

Mixing container and analyzer using the same

The present invention relates to a mixing container for mixing two or more different types of samples, and an analysis apparatus using the mixing container.

¡Portable analyzers can be used in various places, but the work for preparing samples to be analyzed must also be performed in those places. For example, in a liquid sample, an alkaline aqueous solution may be mixed in order to improve analytical performance, or an internal standard substance for calibrating the analyzer may be mixed. It is desired that the operation of preparing such a sample can be performed safely, easily and quickly without burdening the operator and without causing sample contamination.

As an example, for example, Patent Document 1 discloses a structure in which a cap is rotated so that an upper and lower cutter separates two kinds of medicines and cuts an aluminum seal that is stored to mix the two kinds of medicines. Are listed.

Japanese Utility Model Publication No. 7-11544

The above-mentioned conventional methods have a problem that the aluminum seal after cutting becomes an obstacle and the mixing of the two kinds of chemicals cannot be sufficiently performed, and there is a problem that it is difficult to drop the mixed solution.

Therefore, in order to solve the above problems, the present invention can reliably mix two or more kinds of liquid or powdered samples safely, simply, quickly, without contamination, and can easily take out the mixed samples. An object is to provide a mixing container.

In order to solve the above problems, the main features of the mixing container of the present invention are as follows.
That is, the mixing container of the present invention is composed of two or more parts, and has two or more spaces for storing two or more different samples. Two or more parts are structured to be slidable in the axial direction, and by sliding and changing the relative position between the parts, two or more different samples are stored individually, and two or more stored types It is characterized by having a structure capable of realizing a state in which samples of different sizes are mixed.

Further, it is characterized in that a sample mixed from the cap part can be easily taken out by opening a cap part constituted by another part and changing a volume by deforming a part of the mixing container.

Furthermore, the slide part is provided with a lock mechanism, and if the cap part is not attached, the stored sample cannot be slid into a state where two or more different kinds of samples are mixed, and the sample to the outside of the mixing container It has a structure that can prevent leakage and outflow.

According to the present invention, it is possible to provide a mixing container in which two or more kinds of liquid or powdered and particulate samples can be mixed safely, easily, quickly, and without contamination, and the mixed sample can be easily taken out. Become.

It is a figure showing the structure of one embodiment of the present invention, and an operation procedure. It is a figure showing the structure of one embodiment of the present invention, and an operation procedure. It is a figure showing the structure of one embodiment of the present invention, and an operation procedure. It is a figure showing the structure of one embodiment of the present invention, and an operation procedure. It is a figure which shows the stopper mechanism of a sample leakage prevention. It is a figure which shows the scale for adjusting the quantity of a sample. It is a figure which shows the jig | tool of a mixing container. It is a figure which shows the structure figure of another embodiment of this invention, and an operation procedure. It is a figure which shows the structure figure of another embodiment of this invention, and an operation procedure. It is a figure which shows the outline of the apparatus system using the mixing container of this invention.

Embodiments of the present invention will be described below with reference to the drawings.
Embodiment 1
1A to 1C show the structure and operating procedure of a three-component mixing container. FIG. 1D shows details of some of the diagrams of FIG. 1A.

First, as shown in FIG. 1A, the main body A (2) and the main body B (3) have an in-row structure, and can be slid in the axial direction (dashed line in the figure). FIG. 1D shows an α view and a β-β cross section in (a) of FIG. 1A. The stopper 13 is provided on the side surface of the main body B (3), and is fitted into and fixed to the hole 12 provided in the main body A (2).

As shown in FIG. 1D, the hole portion 12 has a notch portion 7, and the notch portion 7 reduces the rigidity around the hole portion 12 of the main body A (2), so that the stopper 13 is attached to the hole portion 12. It is easy to insert. The hole 12 is composed of an upper positioning hole 8, a middle positioning hole 9, and a lower positioning hole 10. The width of each hole end is small, and the stopper 13 passes through each hole end. When doing, it receives resistance and moves. This resistance prevents unintentional movement from one positioning hole to another positioning hole, and the stopper 13 has the above three positions (upper position, middle position, lower position). (Position). As shown in FIG. 1D, there is an opening 11 in the β-β cross section, and the sample that has entered from above the mixing container passes through this opening 11 and flows downward in the mixing container.

In FIG. 1A (a), when the main body B (3) is moved to the above-described upper positioning hole 8 and the sample 1 (4) is poured from the main body B (3), the sample 1 (4) becomes an arrow in the figure. As shown by the solid line with the mark, the sample 1 (4) is accumulated in the space formed by the bottom 1 and the main body A (2) through each opening. After the sample 1 (4) is poured into the required amount, as shown in FIG. 1A (b), the main body B (3) is moved to the middle positioning hole 9, and the sample 1 (4) is inserted. Block the opening entrance of the space. In this state, when the sample 2 (5) is poured from the main body B (3), it accumulates in a space formed by the main body A (2) and the main body B (3).

Further, as shown in FIG. 1A (c), when the main body B (3) is moved to the lower positioning hole 10, the opening entrance of the space where the sample 2 (5) is accumulated is blocked. If this state is maintained, the sample 1 (4) and the sample 2 (5) can be held without being mixed or coming out of the container.

In FIG. 1B (a), when a required amount of sample 3 (6) is dispensed into the main body B (3), it collects in the space formed by the main body A (2) and the main body B (3). Thereafter, as shown in FIG. 1B (b), the cap portion 14 is screwed into the main body B (3) to close the space formed by the main body A (2) and the main body B (3). In this state, as shown in FIG. 1B (c), when the main body B (3) is slid to the upper position, the sample 2 (5) and the sample 3 (6) are collected, and the sample 1 (4) is accumulated. The sample 20 is obtained by mixing the three samples.

As shown in FIG. 1C (a), when the mixing container 33 is turned upside down, the mixed sample 20 flows into the main body B (3). In this state, as shown in FIG. 1C (b), when the cap 17 of the cap portion 14 is opened and the bottom 1 is pushed in the direction of the arrow, a part 21 of the mixed sample 20 is poured into the spout 18 of the cap portion 14. Extruded from.

Here, the bottom 1 comes out of a flexible material (for example, silicon rubber) that can be deformed, and as shown in FIG. 1C (b), the bottom 1 is pushed in the direction of the arrow, thereby mixing the container. Since it is recessed inside 33, the gas in the mixing container is compressed, and the mixed sample 20 can be discharged from the spout 18.

The main bodies A and B constituting the mixing container 33 described above are materials that satisfy chemical resistance, particularly strong resistance to strong alkaline aqueous solution, excellent moldability, and the like, and are inexpensive materials. Is required. Therefore, PP (polypropylene) is used in the present embodiment. The main bodies A and B are each formed by injection molding. Assemble body B into body A by press fitting.

The size of the mixing container 33 is preferably a palm size. The reason is that the mixing container 33 is held and operated. If it is too large, the amount of liquid to be mixed increases, and it becomes necessary to prepare a larger amount than the desired mixing amount. This is because the amount to be used increases and waste occurs.

FIG. 2 is a view showing a lock mechanism for preventing sample leakage.
As shown in FIG. 2 (a), the main body A (2) and the main body B (3) do not slide because the catch portion 25 of the main body A (2) is engaged with the convex portion 24 of the main body B (3). It is locked to. In this state, as shown in FIG. 2 (b), when the cap portion 14 is screwed into the main body A (2), the wedge portion 23 of the cap portion 14 becomes the hook portion 25 and the main body B of the main body A (2). (3) bite into the convex part 24, the hook part 25 of the main body A (2) comes off from the convex part 24 of the main body B (3), and the lock is released. When the lock is released, as shown in FIG. 2C, the main body B (3) can be slid to the upper position, and the sample 2 (5) and the sample 3 (6) become the sample 1. (4) The sample 20 which flows into the side and mixed is made.

With this structure, since the main body A (2) and the main body B (3) cannot be slid unless the cap portion 14 is screwed into the main body A (2), the sample 1 (4) and the sample 2 (5) Mixing or leakage outside the container 33 can be prevented.

FIG. 3 is a diagram showing a scale for adjusting the amount of the sample. (A) is sectional drawing of a mixing container, (b) shows the figure which expanded the scale when it sees from (gamma) position shown by (a). It is the figure which showed the scale 27 for adjusting the quantity which puts the sample 3 (6) into the main body B (3). Here, the main body B (3) is made of a transparent material, and the sample 3 (6) can be confirmed from the outside of the main body B (3). The main body B (3) is provided with a scale 27 as shown by an arrow γ in FIG. 3, and the amount of the sample 3 (6) poured can be adjusted according to the scale. The scale 27 may be easily understood by changing the color.

FIG. 4 is a diagram showing the jig 28 when the mixing container 33 is used.
As shown in FIG. 4, the main body A (2) is inserted into the groove of the jig 28 with the error portion 29 provided on the main body A (2), thereby allowing the container 33 to stand up. The jig 28 is fixed to the floor surface and can be held so as not to move even if force is applied to the container 33. By doing so, the cap portion 14 can be screwed into the main body B (3) without having the main body A (2) or the main body B (3).

The mixing container shown in Embodiment 1 has a structure capable of mixing three liquids, but two liquids can also be mixed. Since the mixed liquid is usually sufficient if two or three liquids can be mixed, the mixing container having this structure is versatile.

<< Embodiment 2 >>
5A and 5B are structural diagrams and operation flows of another embodiment of the present invention.
The main structural differences from FIGS. 1A to 1D shown in Embodiment 1 are that the space for inserting the sample 2 (5) is omitted, and the two samples of only the sample 1 (4) and the sample 3 (6) are omitted. Is to be mixed. Further, as shown in the γ view of FIG. 5B, since only two samples are mixed, the stopper 13 only needs to be located at two positions, the upper positioning hole 8 and the lower positioning hole 10.

First, as shown in FIG. 5A (a), when the main body B (3) is slid to the upper position and the sample 1 is poured, the sample 1 (4) is placed in the space formed by the bottom 1 and the main body A (2). Accumulate.

Next, as shown in FIG. 5A (b), the body B (3) is slid to the lower position to close the space in which the sample 1 (4) is placed. In this state, the sample 1 (4) is held in the container 33. Also, as shown in FIG. 5A (c), the sample 3 (6) is poured into the space formed by the main body B (3) and the main body A (2), and the cap portion 14 is screwed into the main body A (2). The space containing the sample 3 (6) is closed.

Next, as shown in (d) of 5A, when the main body B (3) is slid to the upper position, the sample 3 (6) flows into the same space as the sample 1 (4), and the mixed sample 20 is it can.

The mixing container shown in Embodiment 2 is characterized by a simple structure, and has an advantage in terms of manufacturing cost. Therefore, when mixing two liquids, the container of this structure can be used.
Although omitted in FIG. 5A, a lock mechanism for preventing sample leakage similar to FIG. 2 may be provided.

<< Embodiment 3 >>
FIG. 6 is a diagram showing an outline of the entire apparatus system using the mixing container 33 of the present invention.
A part 21 of the sample mixed from the mixing container 33 is put into a sample cup 35 fixed to a tray 34 provided with a hole 31. The measurement container 39 is lowered with respect to the sample cup 35, and the holding arm 37 is hooked on the protruding portion of the sample cup 35 and held.

At this time, an O-ring (not shown) is crushed, and confidentiality between the measurement container 39 and the sample cup 35 is maintained. The measurement container 39 is provided with a handle 38 for facilitating holding and a nozzle 36 for introducing vaporized gas generated from the sample in the sample bottle 35 into the analyzer 40. Although not shown, the nozzle 36 and the sample cup 35 are connected inside the measurement container 39. The measurement container 39 is set in the sample introduction unit 42 of the analyzer 40. After the setting, the sample gas vaporized in the sample cup 35 is introduced into the analyzer 40 and the components of the part 22 of the mixed sample are analyzed, and the analysis result is displayed on the operation panel 41.
In addition, this invention is not limited to an above-described Example, Various modifications are included.

1: Bottom,
2: Body A,
3: Body B,
4: Sample 1,
5: Sample 2,
6: Sample 3,
7: Notch,
8: Upper positioning hole,
9: Hole for middle positioning,
10: Lower positioning hole,
11: opening,
12: hole,
13: Stopper
14: Cap part,
15: Screw part,
16: Joint,
17: Cap,
18: Spout,
19: seal part,
20: mixed sample,
21: part of the mixed sample,
23: Wedge part,
24: convex part,
25: hook part,
27: Scale,
28: jig,
29: Ella,
31: hole,
33: mixing container,
34: Tray,
35: Sample cup,
36: nozzle,
37: holding arm,
38: Handle,
39: Measuring container,
40: analyzer
41: Operation panel,
42: Sample introduction unit.

Claims

A first housing and a second housing that are slidable in the axial direction;
In the first casing, an outer wall of the casing is slidable in the axial direction along an inner wall of the second casing;
A first state in which a plurality of spaces for individually storing two or more samples are formed by sliding the first casing to a first predetermined position;
By sliding the first casing to a second predetermined position, the first casing has a structure that can be changed to a second state in which two or more samples in the first state are mixed with each other. Mixing container.
The first and second casings allow the opening of the partition to be sealed by a partition having an opening that allows a sample flowing from above to pass therethrough, and the slide of the first and second casings. Having a sealing part,
Sliding the first and second housings to move the sealing part, open and close the opening, and inject and store the sample into a desired space of the plurality of spaces. The mixing container according to claim 1.
By sliding the first and second casings, all of the openings are opened, and two or more samples individually stored in a plurality of spaces are placed in a space below the second casing. The mixing container according to claim 1, wherein the mixing container is mixed.
A cap for sealing the sample inlet of the first housing;
By rotating so that the cap portion is downward and the space below the second housing is upward,
The mixing container according to claim 3, further comprising stirring the mixed sample mixed in a space below the second casing.
The first predetermined position and the second predetermined position are set by holding a stopper provided in the first casing in a hole-shaped portion provided in the second casing. The mixing container according to claim 1.
A projection provided on the outer wall of the first housing and a recess provided on the inner wall of the second housing;
By fitting the protrusion and the recess, the change in the relative position between the first housing and the second housing is suppressed, so that the airtightness of the sample stored in the space is maintained. 2. The mixing container according to claim 1, wherein the sample leaks and flows out to the outside.
A mixing container according to any one of claims 1 to 6,
A sample cup for mixing a sample stored in the mixing container with a sample to be analyzed, and
A measurement container attached to the sample cup;
A sample introduction unit for introducing the measurement container,
An analyzer for analyzing a mixed liquid mixed in the sample cup.