WO2014166303A3 - Use of multiomic signature to predict diabetes - Google Patents

Use of multiomic signature to predict diabetes Download PDF

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Publication number
WO2014166303A3
WO2014166303A3 PCT/CN2014/000408 CN2014000408W WO2014166303A3 WO 2014166303 A3 WO2014166303 A3 WO 2014166303A3 CN 2014000408 W CN2014000408 W CN 2014000408W WO 2014166303 A3 WO2014166303 A3 WO 2014166303A3
Authority
WO
WIPO (PCT)
Prior art keywords
multiomic
signature
diabetes
predict
predict diabetes
Prior art date
Application number
PCT/CN2014/000408
Other languages
French (fr)
Other versions
WO2014166303A2 (en
Inventor
Juliana Chung-Ngor CHAN
Ronald Ching-Wan MA
Heung Man Lee
Xin Liu
Zhi Bao GAO
Jun Wang
Original Assignee
The Chinese University Of Hong Kong
Bgi-Hong Kong Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Chinese University Of Hong Kong, Bgi-Hong Kong Co., Ltd. filed Critical The Chinese University Of Hong Kong
Priority to CN201480031292.3A priority Critical patent/CN105431552B/en
Publication of WO2014166303A2 publication Critical patent/WO2014166303A2/en
Publication of WO2014166303A3 publication Critical patent/WO2014166303A3/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/154Methylation markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers

Abstract

Disclosed herein are methods of using genomic markers to predict the occurrence of diabetes in human subjects, and methods of using multiomic data to identify such markers.
PCT/CN2014/000408 2013-04-12 2014-04-14 Use of multiomic signature to predict diabetes WO2014166303A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201480031292.3A CN105431552B (en) 2013-04-12 2014-04-14 Use of multiomic markers for predicting diabetes

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361811639P 2013-04-12 2013-04-12
US61/811,639 2013-04-12

Publications (2)

Publication Number Publication Date
WO2014166303A2 WO2014166303A2 (en) 2014-10-16
WO2014166303A3 true WO2014166303A3 (en) 2015-07-16

Family

ID=51690067

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2014/000408 WO2014166303A2 (en) 2013-04-12 2014-04-14 Use of multiomic signature to predict diabetes

Country Status (2)

Country Link
CN (1) CN105431552B (en)
WO (1) WO2014166303A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109716135A (en) * 2016-06-21 2019-05-03 河谷控股Ip有限责任公司 The treatment of cancer of efflux body guidance
CN109979534B (en) * 2017-12-28 2021-07-09 浙江安诺优达生物科技有限公司 C site extraction method and device
CN109295197A (en) * 2018-08-31 2019-02-01 南京金域医学检验所有限公司 BSND gene SNP mutational site serotype specific primer and its application in coronary disease disease forecasting
CN117025743A (en) * 2023-08-28 2023-11-10 长江大学 Method for participating in carotenoid biosynthesis in yellow peach through miRNA regulation network based on multiple-study identification

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1571848A (en) * 2001-09-05 2005-01-26 普赖德普罗特奥米克斯公司 Proteins in type 2 diabetes
CN101326439A (en) * 2005-10-11 2008-12-17 特提斯生物科学公司 Diabetes-associated markers and methods of use thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2021502A4 (en) * 2006-05-09 2010-08-25 Mas Metabolic Analytical Servi Novel genes and markers in type 2 diabetes and obesity
ES2936256T3 (en) * 2008-02-01 2023-03-15 Massachusetts Gen Hospital Use of microvesicles in the diagnosis, and prognosis of diseases and medical conditions
US8669057B2 (en) * 2009-05-07 2014-03-11 Veracyte, Inc. Methods and compositions for diagnosis of thyroid conditions
CA2884637A1 (en) * 2012-09-12 2014-03-20 Berg Llc Use of markers in the identification of cardiotoxic agents

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1571848A (en) * 2001-09-05 2005-01-26 普赖德普罗特奥米克斯公司 Proteins in type 2 diabetes
CN101326439A (en) * 2005-10-11 2008-12-17 特提斯生物科学公司 Diabetes-associated markers and methods of use thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
P.IHALMO ET AL.: "Association analysis of podocyte slit diaphragm genes as candidates for diabetic nephropathy", DIABETOLOGIA, 31 December 2008 (2008-12-31), pages 86 - 90 *

Also Published As

Publication number Publication date
CN105431552A (en) 2016-03-23
WO2014166303A2 (en) 2014-10-16
CN105431552B (en) 2020-03-03

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