WO2014162971A1 - Medical solution container and medical solution administration device - Google Patents

Medical solution container and medical solution administration device Download PDF

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Publication number
WO2014162971A1
WO2014162971A1 PCT/JP2014/058828 JP2014058828W WO2014162971A1 WO 2014162971 A1 WO2014162971 A1 WO 2014162971A1 JP 2014058828 W JP2014058828 W JP 2014058828W WO 2014162971 A1 WO2014162971 A1 WO 2014162971A1
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chemical solution
chemical
container
solution container
outflow port
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PCT/JP2014/058828
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French (fr)
Japanese (ja)
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内山　城司
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テルモ株式会社
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M5/14248—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14212—Pumping with an aspiration and an expulsion action
    • A61M5/14216—Reciprocating piston type
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/36—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests with means for eliminating or preventing injection or infusion of air into body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M5/14248—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type
    • A61M2005/14252—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type with needle insertion means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2209/00—Ancillary equipment
    • A61M2209/04—Tools for specific apparatus
    • A61M2209/045—Tools for specific apparatus for filling, e.g. for filling reservoirs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14212—Pumping with an aspiration and an expulsion action
    • A61M5/1424—Manually operated pumps

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Media Introduction/Drainage Providing Device (AREA)

Abstract

A medical solution container (4) is adapted for use in a medical solution administration device and comprises a deformable soft section (41), a hard section (42) which has a predetermined shape and which forms a medical solution containing space (40) in cooperation with the soft section (41), and an outlet opening (441) which is provided in the hard section (42) and through which a medical solution flows out of the medical solution containing space (40).

Description

薬液容器および薬液投与装置Chemical solution container and chemical solution administration device
　本発明は、薬液容器および薬液投与装置に関する。 The present invention relates to a chemical solution container and a chemical solution administration device.
　従来、インスリン等の薬液を使用者の体内に投与する薬液投与装置として、ポンプで所定量の薬液を送出し、当該薬液を継続的に体内に投与するものが知られている（例えば、特許文献１参照）。
　特許文献１に記載の装置は、薬液を収容するリザーバー（薬液容器）と、リザーバーの流出口からカニューレに薬液を導く可撓性の導管と、導管内の薬液を送出するための手動の蠕動ポンプとを備え、使用者が押しボタンを押すたびに導管が蠕動ポンプで締め付けられ、所定量の薬液が送出されるように構成されている。 2. Description of the Related Art Conventionally, as a chemical solution administration device that administers a chemical solution such as insulin into a user's body, a device that sends a predetermined amount of the chemical solution with a pump and continuously administers the chemical solution into the body is known (for example, Patent Documents). 1).
The device described in Patent Document 1 includes a reservoir (chemical solution container) that stores a chemical solution, a flexible conduit that guides the chemical solution from an outlet of the reservoir to a cannula, and a manual peristaltic pump for delivering the chemical solution in the conduit Each time the user presses the push button, the conduit is tightened with a peristaltic pump, and a predetermined amount of chemical solution is delivered.
特表２０１０－５０２３６４号公報Special table 2010-502364
　特許文献１に記載されたような従来の装置では、薬液容器全体が軟質材料で形成されているため、薬液の減少に対して薬液容器の容積を追従させることができるものの、薬液が減少したり容器に外圧が作用したりすると、流出口がつぶれてしまい、薬液が送出されにくくなるという問題がある。 In the conventional apparatus described in Patent Document 1, since the entire chemical solution container is formed of a soft material, the volume of the chemical solution container can follow the decrease in the chemical solution, but the chemical solution is reduced. When an external pressure is applied to the container, there is a problem that the outflow port is crushed and it is difficult to send the chemical solution.
　本発明の主な目的は、薬液の減少に対して容積を追従させることができ、薬液を確実に送出できる薬液容器および薬液投与装置を提供することにある。 The main object of the present invention is to provide a chemical solution container and a chemical solution administration device that can follow the volume with respect to the decrease of the chemical solution and can reliably deliver the chemical solution.
　本発明の薬液容器は、薬液投与装置に用いられる薬液容器であって、変形可能な軟質部と、所定の形状を有し、前記軟質部とともに薬液収容空間を形成する硬質部と、前記硬質部に設けられ、前記薬液収容空間から薬液が流出する流出口とを備えていることを特徴とする。 The drug solution container of the present invention is a drug solution container used for a drug solution administration device, having a deformable soft part, a hard part having a predetermined shape and forming a drug solution containing space together with the soft part, and the hard part And an outflow port through which the chemical solution flows out from the chemical solution storage space.
　本発明によれば、軟質部が設けられているため、薬液の減少に対して薬液容器の容積を追従させることができる。また、薬液の流出口が硬質部に設けられているため、当該流出口がつぶれてしまうことを防止でき、薬液を確実に送出することができる。 According to the present invention, since the soft part is provided, the volume of the chemical solution container can follow the decrease in the chemical solution. Moreover, since the outflow port of a chemical | medical solution is provided in the hard part, the said outflow port can be prevented from being crushed and a chemical | medical solution can be sent out reliably.
　本発明の薬液容器は、前記薬液収容空間に前記薬液を充填するための充填口を備え、前記充填口は、前記薬液収容空間に対して前記流出口と同じ側に設けられていることが好ましい。
　本発明によれば、充填口が流出口と同じ側に設けられているため、薬液容器を引っくり返して充填口から薬液を充填するときに、流出口が上方に向くことになる。このため、薬液容器中の気泡を流出口から外部に逃がすことができ、薬液容器中の気泡を確実に排出することができる。 The chemical solution container of the present invention preferably includes a filling port for filling the chemical solution storage space with the chemical solution, and the filling port is provided on the same side as the outflow port with respect to the chemical solution storage space. .
According to the present invention, since the filling port is provided on the same side as the outflow port, the outflow port is directed upward when the chemical solution container is turned over to be filled with the chemical solution. For this reason, the bubbles in the chemical solution container can escape from the outlet to the outside, and the bubbles in the chemical solution container can be reliably discharged.
　本発明の薬液容器において、前記充填口は、当該充填口を上方に向けたときに前記流出口よりも下方の位置に設けられていることが好ましい。
　本発明によれば、充填口が流出口よりも下方に位置するため、充填口から充填された薬液で気泡を上方の流出口に向けて押し出すことができ、薬液容器中の気泡をさらに確実に排出することができる。 In the chemical solution container of the present invention, it is preferable that the filling port is provided at a position below the outflow port when the filling port is directed upward.
According to the present invention, since the filling port is located below the outflow port, bubbles can be pushed out toward the upper outflow port by the chemical liquid filled from the filling port, and the bubbles in the chemical solution container can be more reliably secured. Can be discharged.
　本発明の薬液容器において、前記硬質部における前記薬液収容空間に臨む位置には、前記薬液収容空間から離間する方向に傾斜した傾斜面を有する窪みが設けられ、前記流出口は、前記窪み内に設けられていることが好ましい。
　本発明によれば、傾斜面を有する窪み内に流出口が設けられているため、窪みの傾斜面に沿って気泡を流出口に案内することができるので、気泡の排出をさらに促進することができる。 In the chemical solution container of the present invention, a recess having an inclined surface inclined in a direction away from the chemical solution storage space is provided at a position facing the chemical solution storage space in the hard portion, and the outflow port is in the recess. It is preferable to be provided.
According to the present invention, since the outflow port is provided in the depression having the inclined surface, the bubbles can be guided to the outflow port along the inclined surface of the depression, so that the discharge of the bubbles can be further promoted. it can.
　本発明の薬液容器において、前記流出口の周囲には、前記薬液収容空間に向けて突出した突出部が設けられていることが好ましい。
　本発明によれば、流出口の周囲に複数の突出部が設けられているため、薬液の減少に伴って軟質部が変形した場合でも、突出部で軟質部を流出口から浮かせた状態にすることができ、軟質部が流出口を塞いでしまうことを防止することができる。 The chemical | medical solution container of this invention WHEREIN: It is preferable that the protrusion part which protruded toward the said chemical | medical solution storage space is provided around the said outflow port.
According to the present invention, since the plurality of projecting portions are provided around the outflow port, even when the soft portion is deformed with the decrease in the chemical solution, the projecting portion causes the soft portion to float from the outflow port. It is possible to prevent the soft part from blocking the outflow port.
　本発明の薬液投与装置は、前述した本発明の薬液容器と、前記薬液容器から薬液を送出する薬液ポンプとを備えていることを特徴とする。
　本発明によれば、前述した薬液容器の効果を奏する薬液投与装置を得ることができる。 The chemical solution administration device of the present invention includes the above-described chemical solution container of the present invention and a chemical solution pump for delivering the chemical solution from the chemical solution container.
ADVANTAGE OF THE INVENTION According to this invention, the chemical | medical solution administration apparatus with the effect of the chemical | medical solution container mentioned above can be obtained.
本発明の一実施形態に係る薬液投与装置を示す分解斜視図。The disassembled perspective view which shows the chemical | medical solution administration apparatus which concerns on one Embodiment of this invention. 薬液容器の分解斜視図。The disassembled perspective view of a chemical | medical solution container. 薬液容器を下方から示す斜視図。The perspective view which shows a chemical | medical solution container from the downward direction. 薬液容器の断面斜視図。The cross-sectional perspective view of a chemical | medical solution container. 薬液容器の送液部の斜視図。The perspective view of the liquid feeding part of a chemical | medical solution container. 薬液ポンプの平面図。The top view of a chemical | medical solution pump. 薬液ポンプの傘状弁の平面図。The top view of the umbrella-shaped valve of a chemical | medical solution pump. 薬液ポンプの傘状弁の側面図。The side view of the umbrella-shaped valve of a chemical | medical solution pump. 傘状弁の断面図。Sectional drawing of an umbrella-shaped valve. 傘状弁の断面図。Sectional drawing of an umbrella-shaped valve. 薬液充填時の薬液容器の作用を説明するための断面図。Sectional drawing for demonstrating the effect | action of the chemical | medical solution container at the time of chemical | medical solution filling. 薬液充填時の薬液容器の作用を説明するための断面図。Sectional drawing for demonstrating the effect | action of the chemical | medical solution container at the time of chemical | medical solution filling. 薬液充填時の薬液容器の作用を説明するための断面図。Sectional drawing for demonstrating the effect | action of the chemical | medical solution container at the time of chemical | medical solution filling. 薬液送出時の薬液容器の作用を説明するための断面図。Sectional drawing for demonstrating the effect | action of the chemical | medical solution container at the time of chemical | medical solution delivery. 薬液送出時の薬液容器の作用を説明するための断面図。Sectional drawing for demonstrating the effect | action of the chemical | medical solution container at the time of chemical | medical solution delivery. 本発明の変形例に係る傘状弁の断面図。Sectional drawing of the umbrella-shaped valve which concerns on the modification of this invention. 本発明の変形例に係る傘状弁の断面図。Sectional drawing of the umbrella-shaped valve which concerns on the modification of this invention.
　以下、本発明の一実施形態を図面に基づいて説明する。
　図１において、薬液投与装置１は、筐体２と、使用者の皮膚に針やカテーテル等を穿刺する穿刺部３と、薬液を収容する薬液容器４と、薬液容器４内の薬液を穿刺部３に送出する薬液ポンプ５と、薬液ポンプ５の動作を制御する制御部６とを備えている。 Hereinafter, an embodiment of the present invention will be described with reference to the drawings.
In FIG. 1, a drug solution administration device 1 includes a housing 2, a puncture unit 3 that punctures a user's skin with a needle, a catheter, and the like, a drug solution container 4 that stores a drug solution, and a puncture unit that stores a drug solution in the drug solution container 4. 3 is provided with a chemical liquid pump 5 to be sent to 3 and a control unit 6 for controlling the operation of the chemical liquid pump 5.
　筐体２は、上部が開口した下筐体２１と、下筐体２１の開口を塞ぐ上筐体２２とを備えている。下筐体２１の開口内には、下筐体２１と上筐体２２とにより空間が形成され、当該空間内に、穿刺部３、薬液容器４、薬液ポンプ５、および制御部６が収容されている。このように、筐体２内に一式を収容することで、薬液投与装置１を小型かつ携帯可能に構成している。下筐体２１の下面には、両面テープ等の貼付部材が設けられ、当該貼付部材により筐体２を使用者の皮膚に貼付可能となっている。 The housing 2 includes a lower housing 21 whose upper portion is open, and an upper housing 22 that closes the opening of the lower housing 21. In the opening of the lower housing 21, a space is formed by the lower housing 21 and the upper housing 22, and the puncture unit 3, the chemical solution container 4, the chemical solution pump 5, and the control unit 6 are accommodated in the space. ing. Thus, by accommodating a set in the housing 2, the drug solution administration device 1 is configured to be small and portable. An adhesive member such as a double-sided tape is provided on the lower surface of the lower housing 21, and the housing 2 can be applied to the user's skin by the adhesive member.
　穿刺部３は、押込部材３１と、図示しない針やカテーテルの穿刺部材とを備え、押込部材３１で穿刺部材を押し込むことで、当該穿刺部材を下筐体２１の裏面から使用者の皮膚に穿刺可能となっている。 The puncture unit 3 includes a push-in member 31 and a puncture member for a needle or catheter (not shown). By pushing the puncture member with the push-in member 31, the puncture member is punctured from the back surface of the lower housing 21 into the user's skin. It is possible.
　薬液容器４は、図２から図５に示すように、変形可能な軟質部４１と、所定の形状を有し、軟質部４１とともに薬液収容空間４０を形成する硬質部４２と、軟質部４１を挟んで硬質部４２の反対側に設けられ、軟質部４１を覆うカバー部４３と、薬液収容空間４０から薬液が流出する流出口４４１を有する送液部４４と、薬液容器４に規定量を超える薬液が充填されたときに軟質部４１が及ぶ位置に設けられ、軟質部４１の当接により薬液の過充填を検知する過充填検知部４５と、薬液容器４に規定量の薬液が充填されたときに軟質部４１が及ぶ位置に設けられ、軟質部４１の当接により薬液の満充填を検知する満充填検知部４６とを備えている。この薬液容器４は、硬質部４２が下筐体２１側に向いた状態で筐体２内に収容されている。 As shown in FIGS. 2 to 5, the chemical solution container 4 includes a deformable soft portion 41, a hard portion 42 having a predetermined shape and forming a chemical solution containing space 40 together with the soft portion 41, and the soft portion 41. It is provided on the opposite side of the hard part 42 across the cover part 43 that covers the soft part 41, the liquid supply part 44 that has the outlet 441 through which the chemical liquid flows out from the chemical liquid storage space 40, and exceeds the prescribed amount in the chemical liquid container 4. An overfill detection unit 45 is provided at a position where the soft part 41 reaches when the chemical liquid is filled, and detects overfilling of the chemical liquid by contact of the soft part 41, and the chemical liquid container 4 is filled with a prescribed amount of the chemical liquid. A full-fill detection unit 46 that is provided at a position where the soft portion 41 sometimes reaches and detects the full-filling of the chemical liquid by the contact of the soft portion 41 is provided. The chemical solution container 4 is accommodated in the housing 2 with the hard portion 42 facing the lower housing 21 side.
　軟質部４１は、親水性を有する材料、例えば、ポリエチレン、より好ましくは高密度ポリエチレン（ハイデンポリエチレンとも称する）で形成された薄膜であり、例えば、３０～５０μｍの厚さに形成されている。この軟質部４１は、袋状に形成され、薬液の増減に合わせて薬液収容空間４０の容積を追従可能な追従部４１１と、追従部４１１に沿って形成され、硬質部４２とカバー部４３とで挟持される平面状の外縁部４１２とを備えている。 The soft part 41 is a thin film formed of a hydrophilic material, for example, polyethylene, more preferably high density polyethylene (also referred to as Hayden polyethylene), and has a thickness of, for example, 30 to 50 μm. The soft portion 41 is formed in a bag shape, is formed along the follower 411 that can follow the volume of the chemical solution storage space 40 in accordance with the increase or decrease of the chemical solution, the follower 411, and the hard portion 42 and the cover portion 43. And a planar outer edge portion 412 sandwiched between the two.
　硬質部４２は、ポリエチレン等の親水性を有する材料、好ましくは軟質部４１と同じ材料で形成された所定形状の硬質部材で構成されている。この硬質部４２は、軟質部４１の追従部４１１と同程度の大きさおよび同程度の深さを有する凹部４２１を有している。凹部４２１の底面４２２には、円錐状に窪んで形成され、薬液収容空間４０から離間する方向に傾斜した傾斜面４２８を有する窪み４２３と、窪み４２３の底部に設けられ、送液部４４が嵌合する嵌合孔４２４とが設けられている。凹部４２１の側面４２５は、対向する側面４２５との間隔が底面４２２に向かうに従って狭くなる曲面状に形成されている。この側面４２５の底面４２２近傍には、薬液収容空間４０に薬液を充填するための充填口４２６が設けられている。このような位置に充填口４２６を設けることにより、充填口４２６が薬液収容空間４０に対して流出口４４１と同じ側に位置するとともに、充填口４２６を上方に向けたときに、充填口４２６が流出口４４１よりも下方に位置することになる。また、硬質部４２に流出口４４１および充填口４２６を設けることで、このような位置関係を確実に規定することができる。充填口４２６は、ゴムや樹脂等の弾性部材で構成されたキャップ４２７で封止されている。 The hard part 42 is composed of a hard member having a predetermined shape formed of a hydrophilic material such as polyethylene, preferably the same material as the soft part 41. The hard part 42 has a concave part 421 having the same size and the same depth as the follower part 411 of the soft part 41. The bottom surface 422 of the recess 421 is formed in a conical recess and has a recess 423 having an inclined surface 428 inclined in a direction away from the chemical solution storage space 40, and a bottom of the recess 423. A mating hole 424 is provided. The side surface 425 of the recess 421 is formed in a curved surface shape such that the distance from the opposite side surface 425 becomes narrower toward the bottom surface 422. Near the bottom surface 422 of the side surface 425, a filling port 426 for filling the chemical solution storage space 40 with the chemical solution is provided. By providing the filling port 426 at such a position, the filling port 426 is positioned on the same side as the outflow port 441 with respect to the chemical solution storage space 40, and when the filling port 426 is directed upward, It will be located below the outflow port 441. Further, by providing the outflow port 441 and the filling port 426 in the hard portion 42, such a positional relationship can be reliably defined. The filling port 426 is sealed with a cap 427 made of an elastic member such as rubber or resin.
　カバー部４３は、ポリエチレン等の親水性を有する材料、好ましくは軟質部４１と同じ材料で形成された所定形状の硬質部材で構成され、軟質部４１を保護可能に設けられている。このカバー部４３は、軟質部４１の追従部４１１と同程度の大きさおよび同程度の深さを有する凹部４３１を有している。この凹部４３１は、薬液容器４に規定量の薬液が充填されたときの軟質部４１の形状に倣って形成され、薬液容器４に規定量の薬液が充填されたときに、当接面としての底面４３２および当接面としての側面４３５に軟質部４１が当接するように形成されている。凹部４３１の底面４３２には、軟質部４１側に開口し、２つの電極としての第１電極４５１を収容する第１電極収容部４３３が設けられている。凹部４３１の側面４３５は、対向する側面４３５との間隔が底面４３２に向かうに従って狭くなる曲面状に形成されている。この側面４３５の底面４３２近傍には、軟質部４１側に開口し、それぞれ２つの第２電極４６１を収容する第２電極収容部４３４が２箇所に設けられている。 The cover portion 43 is formed of a hard member having a predetermined shape formed of a hydrophilic material such as polyethylene, preferably the same material as the soft portion 41, and is provided so as to protect the soft portion 41. The cover portion 43 has a concave portion 431 having the same size and the same depth as the follower portion 411 of the soft portion 41. The concave portion 431 is formed following the shape of the soft portion 41 when the chemical solution container 4 is filled with a prescribed amount of chemical solution, and serves as a contact surface when the chemical solution container 4 is filled with the prescribed amount of chemical solution. The soft portion 41 is formed so as to contact the bottom surface 432 and the side surface 435 as the contact surface. The bottom surface 432 of the recess 431 is provided with a first electrode housing portion 433 that opens to the soft portion 41 side and houses the first electrode 451 as two electrodes. The side surface 435 of the recess 431 is formed in a curved surface shape such that the distance from the opposite side surface 435 decreases toward the bottom surface 432. In the vicinity of the bottom surface 432 of the side surface 435, two second electrode housing portions 434 that open to the soft portion 41 side and house two second electrodes 461, respectively, are provided.
　送液部４４は、親水性を有する材料、好ましくはポリエチレンで形成され、硬質部４２に設けられている。この送液部４４は、流出口４４１と、流出口４４１の周囲に設けられ、薬液収容空間４０に向けて突出した複数の突出部４４２とを備えている。 The liquid feeding part 44 is made of a hydrophilic material, preferably polyethylene, and is provided in the hard part 42. The liquid feeding part 44 includes an outlet 441 and a plurality of protrusions 442 provided around the outlet 441 and protruding toward the chemical solution storage space 40.
　過充填検知部４５は、第１電極４５１と、軟質部４１に設けられた第１電極パッド４５２とを備えている。この過充填検知部４５は、薬液の充填に伴い軟質部４１が変形して第１電極パッド４５２と第１電極４５１とが当接することで過充填を検知可能に構成されている。第１電極４５１は、薬液容器４に規定量を超える薬液が充填されたときの第１電極パッド４５２の軌跡上であって、薬液が過充填されたときに軟質部４１が及ぶ位置に設けられている。また、第１電極４５１は、先端が凹部４３１の底面４３２から引っ込んだ状態で第１電極収容部４３３に収容され、第１電極パッド４５２との当接部である先端が第１電極収容部４３３内に入り込んでいる。第１電極パッド４５２は、薄膜状に形成され、軟質部４１の変形に合わせて変形可能とされている。 The overfill detection unit 45 includes a first electrode 451 and a first electrode pad 452 provided on the soft part 41. The overfilling detection unit 45 is configured to detect overfilling when the soft part 41 is deformed with the filling of the chemical solution and the first electrode pad 452 and the first electrode 451 come into contact with each other. The first electrode 451 is provided on the locus of the first electrode pad 452 when the chemical solution container 4 is filled with a chemical solution exceeding a specified amount, and is provided at a position where the soft part 41 reaches when the chemical solution is overfilled. ing. The first electrode 451 is housed in the first electrode housing portion 433 with the tip retracted from the bottom surface 432 of the recess 431, and the tip that is a contact portion with the first electrode pad 452 is the first electrode housing portion 433. It is in the inside. The first electrode pad 452 is formed in a thin film shape and can be deformed in accordance with the deformation of the soft portion 41.
　満充填検知部４６は、第２電極４６１と、軟質部４１に設けられた第２電極パッド４６２とを備え、薬液の充填に伴い軟質部４１が変形して第２電極パッド４６２と第２電極４６１とが当接することで満充填を検知可能に構成されている。第２電極４６１は、薬液容器４に規定量の薬液が充填されたときの第２電極パッド４６２の位置、すなわち薬液が満充填されたときに軟質部４１が及ぶ位置に設けられている。各第２電極４６１は、先端が凹部４３１の形状に沿うように第２電極収容部４３４内に配置され、内側の第２電極４６１よりも外側の第２電極４６１の方が薬液収容空間側に突出している。第２電極パッド４６２は、薄膜状に形成され、軟質部４１の変形に合わせて変形可能とされている。 The full-fill detection unit 46 includes a second electrode 461 and a second electrode pad 462 provided on the soft part 41. The soft part 41 is deformed as the chemical solution is filled, and the second electrode pad 462 and the second electrode 461 is configured to be able to detect full filling. The second electrode 461 is provided at the position of the second electrode pad 462 when the chemical liquid container 4 is filled with a prescribed amount of chemical liquid, that is, at the position where the soft part 41 reaches when the chemical liquid is fully filled. Each second electrode 461 is disposed in the second electrode housing portion 434 so that the tip thereof follows the shape of the recess 431, and the second electrode 461 outside the inner second electrode 461 is closer to the chemical solution housing space. It protrudes. The second electrode pad 462 is formed in a thin film shape and can be deformed in accordance with the deformation of the soft portion 41.
　薬液ポンプ５は、図６に示すように、薬液が流入する薬液流入路５１と、薬液が送出される薬液送出路５２と、薬液流入路５１と薬液送出路５２とを接続する接続路５３と、接続路５３の途中に設けられ、当該接続路５３に連通するシリンダ５４と、シリンダ５４内に摺動自在に設けられたピストン５５と、薬液流入路５１と接続路５３との間に設けられ、接続路５３から薬液流入路５１への薬液の逆流を防止する第１逆止弁５６と、薬液送出路５２と接続路５３との間に設けられ、薬液送出路５２から接続路５３への薬液の逆流を防止する第２逆止弁５７と、前記ピストン５５を駆動する駆動部５８とを備えている。 As shown in FIG. 6, the chemical liquid pump 5 includes a chemical liquid inflow path 51 through which the chemical liquid flows in, a chemical liquid delivery path 52 through which the chemical liquid is delivered, and a connection path 53 that connects the chemical liquid inflow path 51 and the chemical liquid delivery path 52. The cylinder 54 provided in the middle of the connection path 53, communicated with the connection path 53, the piston 55 slidably provided in the cylinder 54, and provided between the chemical liquid inflow path 51 and the connection path 53. The first check valve 56 for preventing the backflow of the chemical liquid from the connection path 53 to the chemical liquid inflow path 51 and the chemical liquid delivery path 52 and the connection path 53 are provided, and the chemical liquid delivery path 52 to the connection path 53 is provided. A second check valve 57 for preventing the back flow of the chemical solution and a drive unit 58 for driving the piston 55 are provided.
　薬液流入路５１、薬液送出路５２、接続路５３、シリンダ５４、第１逆止弁５６、および第２逆止弁５７は、所定量の薬液を送出可能に構成された送液ブロック７に設けられている。送液ブロック７は、第１接続管１１を介して薬液容器４に接続された流入側ブロック７１と、第２接続管１２を介して穿刺部３に接続された流出側ブロック７２と、流入側ブロック７１および流出側ブロック７２に挟まれたシリンダブロック７３とを備えている。 The chemical solution inflow path 51, the chemical solution delivery path 52, the connection path 53, the cylinder 54, the first check valve 56, and the second check valve 57 are provided in the liquid supply block 7 configured to be able to deliver a predetermined amount of chemical liquid. It has been. The liquid feeding block 7 includes an inflow side block 71 connected to the drug solution container 4 via the first connection pipe 11, an outflow side block 72 connected to the puncture section 3 via the second connection pipe 12, and an inflow side. And a cylinder block 73 sandwiched between the block 71 and the outflow side block 72.
　薬液流入路５１は、流入側ブロック７１に設けられている。流入側ブロック７１における薬液流入路５１と接続路５３との接続部分には、第１逆止弁５６の弁座としての第１弁座７１１が設けられている。 The chemical solution inflow path 51 is provided in the inflow side block 71. A first valve seat 711 as a valve seat of the first check valve 56 is provided at a connection portion between the chemical solution inflow passage 51 and the connection passage 53 in the inflow side block 71.
　薬液送出路５２は、流出側ブロック７２に設けられている。流出側ブロック７２における薬液送出路５２と接続路５３との接続部分には、第２逆止弁５７を収容する第２収容空間７２０が設けられている。 The chemical solution delivery path 52 is provided in the outflow side block 72. A second accommodation space 720 for accommodating the second check valve 57 is provided at a connection portion between the chemical solution delivery path 52 and the connection path 53 in the outflow side block 72.
　接続路５３およびシリンダ５４は、シリンダブロック７３に設けられている。シリンダブロック７３における接続路５３と薬液流入路５１との接続部分には、第１逆止弁５６を収容する第１収容空間７３０が設けられている。シリンダブロック７３における接続路５３と薬液送出路５２との接続部分には、第２逆止弁５７の弁座としての第２弁座７３１が設けられている。 The connection path 53 and the cylinder 54 are provided in the cylinder block 73. A first accommodation space 730 for accommodating the first check valve 56 is provided at a connection portion between the connection path 53 and the chemical liquid inflow path 51 in the cylinder block 73. A second valve seat 731 as a valve seat of the second check valve 57 is provided at a connection portion between the connection path 53 and the chemical solution delivery path 52 in the cylinder block 73.
　第１逆止弁５６は、図７Ａ，図７Ｂおよび図８Ａ，図８Ｂに示すように、軸部５６１と、軸部５６１の中程に設けられた傘部５６２とを備えた傘状弁（アンブレラバルブ）である。傘部５６２は、軸部５６１の外周面に沿った環状に形成されるとともに、当該外周面から軸部５６１の基端側に傾斜した形状とされている。この第１逆止弁５６は、例えば、シリコンゴムにより形成され、硬度がＨｓ３０～７０（好ましくはＨｓ４０）、弾性係数が１～２５ＭＰａ（好ましくは５ＭＰａ）、ポアソン比が０．５、密度が１．１２ｇ／ｃｍ３とされている。第１逆止弁５６は、軸部５６１の基端が第１弁座７１１に設けられた凹部７１２に挿入されるとともに、軸部５６１の先端がシリンダブロック７３に設けられた凹部７３２に挿入され、傘部５６２が第１弁座７１１に当接している。第１弁座７１１には、傘部５６２の下面５６３に臨む突状部７１３が設けられている。突状部７１３は、傘部５６２に沿って環状に形成されるとともに、傘部５６２の下面５６３に倣う傾斜面７１４を有している。すなわち、傾斜面７１４は、第１逆止弁５６が閉じたときに傘部５６２の下面５６３全体と当接するように形成されている。傾斜面７１４の傾斜角は、例えば、８°に形成されている。 As shown in FIGS. 7A, 7B, 8A, and 8B, the first check valve 56 is an umbrella valve including a shaft portion 561 and an umbrella portion 562 provided in the middle of the shaft portion 561 ( Umbrella valve). The umbrella portion 562 is formed in an annular shape along the outer peripheral surface of the shaft portion 561 and has a shape inclined from the outer peripheral surface to the proximal end side of the shaft portion 561. The first check valve 56 is made of, for example, silicon rubber, has a hardness of Hs 30 to 70 (preferably Hs 40), an elastic modulus of 1 to 25 MPa (preferably 5 MPa), a Poisson's ratio of 0.5, and a density of 1 .12 g / cm 3 . In the first check valve 56, the base end of the shaft portion 561 is inserted into the recess 712 provided in the first valve seat 711, and the tip of the shaft portion 561 is inserted into the recess 732 provided in the cylinder block 73. The umbrella portion 562 is in contact with the first valve seat 711. The first valve seat 711 is provided with a protruding portion 713 that faces the lower surface 563 of the umbrella portion 562. The projecting portion 713 is formed in an annular shape along the umbrella portion 562 and has an inclined surface 714 that follows the lower surface 563 of the umbrella portion 562. That is, the inclined surface 714 is formed so as to contact the entire lower surface 563 of the umbrella portion 562 when the first check valve 56 is closed. The inclination angle of the inclined surface 714 is, for example, 8 °.
　第２逆止弁５７は、第１逆止弁５６と同様に構成され、第２弁座７３１は、第１弁座７１１と同様に構成されている。このため、第１逆止弁５６および第２弁座７３１については、第１逆止弁５６の構成の５６の記号を５７に置き換え、第１弁座７１１の構成の７１の記号を７３に置き換えることで説明ができるので、その説明を省略する。 The second check valve 57 is configured in the same manner as the first check valve 56, and the second valve seat 731 is configured in the same manner as the first valve seat 711. Therefore, for the first check valve 56 and the second valve seat 731, the symbol 56 in the configuration of the first check valve 56 is replaced with 57, and the symbol 71 in the configuration of the first valve seat 711 is replaced with 73. Since it can be explained, the explanation is omitted.
　駆動部５８は、回動モータ５８１と、回動モータ５８１の出力軸５８２に設けられた雄ねじ５８３と、出力軸５８２と平行にピストン５５を支持するとともに、雄ねじ５８３が螺合する雌ねじ５８４が形成された移動部材５８５とを備えている。 The drive unit 58 includes a rotation motor 581, a male screw 583 provided on the output shaft 582 of the rotation motor 581, and a female screw 584 that supports the piston 55 in parallel with the output shaft 582 and is screwed with the male screw 583. The moving member 585 is provided.
　制御部６は、薬液ポンプ５を挟んで薬液容器４の反対側に設けられている。この制御部６は、ＣＰＵ（Central Processing Unit）等の制御装置と、ＲＯＭ（Read Only Memory）やＲＡＭ（Random Access Memory）等の記憶装置と、図示しない操作機器との間で情報の送受信を行う送受信装置と、これら装置が敷設された回路基板とを備えている。 The control unit 6 is provided on the opposite side of the chemical solution container 4 with the chemical solution pump 5 interposed therebetween. The control unit 6 transmits and receives information between a control device such as a CPU (Central Processing Unit), a storage device such as a ROM (Read Only Memory) or a RAM (Random Access Memory), and an operation device (not shown). A transmission / reception device and a circuit board on which these devices are laid are provided.
　次に、薬液投与装置１において、インスリン等の薬液を使用者の体内に投与する際の手順を説明する。
　先ず、使用者は、注射器で薬液を吸引する。次いで、薬液投与装置１をひっくり返した後、図９Ａに示すように、充填口４２６に注射針を刺し込み、薬液容器４内に薬液を充填する。薬液容器４内に充填された薬液は、軟質部４１を押し下げ、当該軟質部４１を徐々に下方に変形させる。これにより、薬液容器４内の薬液収容空間４０の体積が増加するため、薬液容器４の内圧が所定値以下に維持される。 Next, a procedure for administering a drug solution such as insulin into the user's body in the drug solution administration apparatus 1 will be described.
First, the user sucks the drug solution with a syringe. Next, after the medicinal solution administration device 1 is turned over, as shown in FIG. 9A, an injection needle is inserted into the filling port 426 to fill the medicinal solution container 4 with the medicinal solution. The chemical solution filled in the chemical solution container 4 pushes down the soft portion 41 and gradually deforms the soft portion 41 downward. Thereby, since the volume of the chemical | medical solution storage space 40 in the chemical | medical solution container 4 increases, the internal pressure of the chemical | medical solution container 4 is maintained below a predetermined value.
　ここで、薬液収容空間４０や充填される薬液中には、気泡が含まれていることがある。この場合でも、充填口４２６が流出口４４１よりも下方に位置しているため、充填口４２６から充填された薬液で気泡を上方の流出口４４１に向けて押し出すことができ、当該気泡が流出口４４１から外部に抜けやすくなる。また、凹部４２１の側面４２５が曲面状に形成されるとともに、流出口４４１の周囲には、当該流出口４４１に向かって上方に傾斜した傾斜面４２８を有する窪み４２３が設けられている。このため、気泡を側面４２５や窪み４２３の傾斜面４２８に沿って流出口４４１に案内することができるとともに、窪み４２３を一時的な気泡貯まりとすることができる。 Here, bubbles may be contained in the chemical solution storage space 40 or the chemical solution to be filled. Even in this case, since the filling port 426 is positioned below the outflow port 441, the bubbles can be pushed out toward the upper outflow port 441 by the chemical liquid filled from the filling port 426, and the bubbles are discharged from the outflow port 441. It becomes easy to come out from 441 outside. In addition, the side surface 425 of the recess 421 is formed in a curved shape, and a recess 423 having an inclined surface 428 inclined upward toward the outlet 441 is provided around the outlet 441. For this reason, while being able to guide a bubble to the outflow port 441 along the inclined surface 428 of the side surface 425 or the hollow 423, the hollow 423 can be used as a temporary bubble storage.
　その後、薬液が規定量充填されると、図９Ｂに示すように、各第２電極パッド４６２が２つの第２電極４６１に当接し、第２電極４６１間が通電する。制御部６は、当該通電を検知すると、規定量の薬液が充填されたことをブザーやランプ等の図示しない報知手段で使用者に報知する。それにもかかわらず、さらに薬液を充填し続けると、図９Ｃに示すように、軟質部４１が第１電極収容部４３３内に入り込むことで、第１電極パッド４５２が２つの第１電極４５１に当接し、第１電極４５１間が通電する。制御部６は、当該通電を検知すると、薬液が過充填されたことを報知手段で使用者に報知する。 Thereafter, when a prescribed amount of chemical solution is filled, as shown in FIG. 9B, each second electrode pad 462 comes into contact with the two second electrodes 461, and the second electrode 461 is energized. When the control unit 6 detects the energization, the control unit 6 notifies the user that a prescribed amount of the chemical solution has been filled by a notifying unit (not shown) such as a buzzer or a lamp. Nevertheless, when the chemical solution is further filled, as shown in FIG. 9C, the soft portion 41 enters the first electrode housing portion 433, so that the first electrode pad 452 contacts the two first electrodes 451. The first electrode 451 is energized. When the control unit 6 detects the energization, the control unit 6 notifies the user that the chemical solution is overfilled by a notification unit.
　薬液容器４への薬液の充填が完了したら、使用者は、薬液投与装置１を皮膚に貼付し、穿刺部３で針等を皮膚に穿刺した後、図示しない操作機器により、薬液の投与量、投与速度等を設定する。そして、使用者が操作機器を介して薬液の投与開始操作を行うと、制御部６が薬液ポンプ５を制御し、回動モータ５８１が出力軸５８２を一方の回転方向に回転させる。これにより、ピストン５５が接続路５３から離間して接続路５３内が負圧状態となるため、図８Ｂに示すように、第１逆止弁５６の傘部５６２が第１弁座７１１から離れて当該第１逆止弁５６が開き、薬液が接続路５３に流れ込む。次いで、回動モータ５８１が出力軸５８２を他方の回転方向に回転させ、ピストン５５を接続路５３に接近させると、接続路５３内が加圧状態となるため、図８Ｂに示すように、第２逆止弁５７が開き、接続路５３内の薬液が薬液送出路５２に送出される。これにより、所定量の薬液が穿刺部３から使用者の体内に投与される。 When the filling of the drug solution into the drug solution container 4 is completed, the user attaches the drug solution administration device 1 to the skin, punctures the skin with a needle or the like with the puncture unit 3, and then uses the operation device (not shown) Set the administration rate. And if a user performs administration start operation of a chemical | medical solution via an operating device, the control part 6 will control the chemical | medical solution pump 5, and the rotation motor 581 will rotate the output shaft 582 to one rotation direction. As a result, the piston 55 is separated from the connection path 53 and the inside of the connection path 53 is in a negative pressure state, so that the umbrella portion 562 of the first check valve 56 is separated from the first valve seat 711 as shown in FIG. 8B. Then, the first check valve 56 is opened, and the chemical solution flows into the connection path 53. Next, when the rotation motor 581 rotates the output shaft 582 in the other rotation direction and the piston 55 approaches the connection path 53, the inside of the connection path 53 is in a pressurized state. 2 The check valve 57 is opened, and the chemical solution in the connection path 53 is sent to the chemical solution delivery path 52. As a result, a predetermined amount of drug solution is administered from the puncture unit 3 into the user's body.
　ここで、各弁座７１１、７３１には、図８Ａに示すように、傘部５６２、５７２の下面５６３、５７３に倣う傾斜面７１４、７３４を有する突状部７１３、７３３が設けられている。このため、各逆止弁５６、５７が閉じている状態で、各傘部５６２、５７２と各弁座７１１、７３１との間の空間を小さくすることができ、いわゆるデッドボリュームを低減することができる。従って、薬液ポンプ５内に気泡が残留することを極力排除することができるので、操作機器で設定された所定量の薬液を確実に送出することができ、薬液ポンプ５からの薬液の送出量の精度を向上させることができる。 Here, as shown in FIG. 8A, the valve seats 711 and 731 are provided with projecting portions 713 and 733 having inclined surfaces 714 and 734 that follow the lower surfaces 563 and 573 of the umbrella portions 562 and 572, respectively. For this reason, in the state which each check valve 56 and 57 is closed, the space between each umbrella part 562 and 572 and each valve seat 711 and 731 can be made small, and what is called dead volume can be reduced. it can. Accordingly, it is possible to eliminate bubbles remaining in the chemical liquid pump 5 as much as possible, so that a predetermined amount of chemical liquid set by the operating device can be reliably delivered, and the amount of chemical liquid delivered from the chemical liquid pump 5 can be reduced. Accuracy can be improved.
　その後も薬液ポンプ５により薬液が送出されると、規定量の薬液が収容された図１０Ａに示す状態から、薬液容器４内の薬液が減少し、軟質部４１が徐々に下方に変形する。これにより、薬液容器４内の薬液収容空間４０の体積が減少するため、薬液容器４の内圧が所定値以上に維持される。そして、薬液容器４内の薬液が残り少なくなると、軟質部４１が硬質部４２の凹部４２１内に落ち込み、図１０Ｂに示すように、凹部４２１の底面４２２に当接し始める。この場合でも、複数の突出部４４２が流出口４４１の周囲に設けられているため、突出部４４２で軟質部４１を流出口４４１から浮かせた状態にすることができ、軟質部４１が流出口４４１を塞いでしまうことを防止することができる。これにより、残りの薬液を突出部４４２間の溝から流出口４４１に導くことができる。また、流出口４４１が硬質部４２に設けられているため、流出口４４１がつぶれてしまうことを防止することができる。従って、薬液容器４内の薬液がなくなるまで、薬液を確実に送出し続けることができる。 Thereafter, when the chemical solution is delivered by the chemical solution pump 5, the chemical solution in the chemical solution container 4 decreases from the state shown in FIG. 10A in which the prescribed amount of chemical solution is stored, and the soft portion 41 is gradually deformed downward. Thereby, since the volume of the chemical | medical solution storage space 40 in the chemical | medical solution container 4 reduces, the internal pressure of the chemical | medical solution container 4 is maintained more than predetermined value. When the chemical solution in the chemical solution container 4 becomes small, the soft portion 41 falls into the concave portion 421 of the hard portion 42 and starts to contact the bottom surface 422 of the concave portion 421 as shown in FIG. 10B. Even in this case, since the plurality of projecting portions 442 are provided around the outflow port 441, the soft portion 41 can be floated from the outflow port 441 by the projecting portion 442. Can be prevented from being blocked. Accordingly, the remaining chemical liquid can be guided from the groove between the protrusions 442 to the outlet 441. Moreover, since the outflow port 441 is provided in the hard part 42, it can prevent that the outflow port 441 collapses. Therefore, the chemical liquid can be reliably delivered until the chemical liquid in the chemical liquid container 4 runs out.
　以上の本実施形態によれば、次のような効果がある。
　すなわち、薬液容器４に軟質部４１が設けられているため、薬液の減少に対して薬液容器４の容積を追従させることができる。また、薬液の流出口４４１が硬質部４２に設けられているため、当該流出口４４１がつぶれてしまうことを防止でき、薬液を確実に送出することができる。 According to the above embodiment, the following effects are obtained.
That is, since the soft part 41 is provided in the chemical solution container 4, the volume of the chemical solution container 4 can follow the decrease in the chemical solution. Moreover, since the outflow port 441 of the chemical solution is provided in the hard portion 42, the outflow port 441 can be prevented from being crushed, and the chemical solution can be reliably delivered.
　また、充填口４２６が流出口４４１と同じ側に設けられているため、薬液投与装置１を引っくり返して充填口４２６から薬液を充填するときに、流出口４４１が上方に向くことになる。このため、薬液容器４中の気泡を流出口４４１から外部に逃がすことができ、薬液容器４中の気泡を確実に排出することができる。 Also, since the filling port 426 is provided on the same side as the outlet 441, the outlet 441 is directed upward when the drug solution administration device 1 is turned over to be filled with the drug solution from the filling port 426. For this reason, the air bubbles in the chemical liquid container 4 can escape to the outside from the outlet 441, and the air bubbles in the chemical liquid container 4 can be reliably discharged.
　また、薬液投与装置１を引っくり返したときに、充填口４２６が流出口４４１よりも下方に位置するため、充填口４２６から充填された薬液で気泡を上方の流出口４４１に向けて押し出すことができ、薬液容器４中の気泡をさらに確実に排出することができる。 Further, when the medicinal solution administration device 1 is turned over, the filling port 426 is positioned below the outflow port 441, so that bubbles can be pushed out toward the upper outflow port 441 with the medicinal solution filled from the filling port 426. The bubbles in the chemical solution container 4 can be discharged more reliably.
　また、傾斜面４２８を有する窪み４２３内に流出口４４１が設けられているため、窪み４２３の傾斜面４２８に沿って気泡を流出口４４１に案内することができるので、気泡の排出をさらに促進することができる。 Further, since the outlet 441 is provided in the recess 423 having the inclined surface 428, the bubbles can be guided to the outlet 441 along the inclined surface 428 of the recess 423, thereby further promoting the discharge of the bubbles. be able to.
　また、流出口４４１の周囲に複数の突出部４４２が設けられているため、薬液の減少に伴って軟質部４１が変形した場合でも、突出部４４２で軟質部４１を流出口４４１から浮かせた状態にすることができ、軟質部４１が流出口４４１を塞いでしまうことを防止することができる。 Moreover, since the some protrusion part 442 is provided around the outflow port 441, even when the soft part 41 deform | transforms with the reduction | decrease of a chemical | medical solution, the soft part 41 is floated from the outflow port 441 by the protrusion part 442 It is possible to prevent the soft portion 41 from blocking the outlet 441.
　なお、本発明は前述の実施形態に限定されるものではなく、本発明の目的を達成できる範囲での変形、改良等は本発明に含まれるものである。
　例えば、薬液容器４において、軟質部４１は、薬液の増減に合わせて薬液収容空間４０の容積させることができれば、任意の材料で形成することができる。
　硬質部４２は、流出口４４１に気泡を案内できる形状であれば、前記実施形態のものに限らない。例えば、底面４２２が流出口４４１に向かって傾斜した形状としてもよいし、側面４２５を対向する側面４２５同士の間隔が底面４２２に向かうに従って狭くなる直線状に形成してもよい。
　カバー部４３は、前記実施形態のものに限らず、例えば、軟質部４１の上方のみを覆うように形成したり、側面４３５を角筒状に形成したりしてもよい。
　送液部４４は、硬質部４２の嵌合孔４２４に嵌合させる構成でなくてもよく、射出成形、押出成形、ブロー成形等で硬質部４２と一体成形してもよい。
　過充填検知部４５および満充填検知部４６は、過充填または満充填を検知可能な任意の構成を採用することができる。例えば、リミットスイッチや圧電素子が採用でき、軟質部４１がリミットスイッチまたは圧電素子を押圧したときの電位変化により、過充填または満充填を検知するようにしてもよい。また、各電極パッド４５２、４６２は、軟質部４１に設けられていなくてもよく、例えば、カバー部４３で各電極パッド４５２、４６２を各電極４５１、４６１に対して近接離間可能に支持してもよい。 It should be noted that the present invention is not limited to the above-described embodiments, and modifications, improvements, and the like within the scope that can achieve the object of the present invention are included in the present invention.
For example, in the chemical solution container 4, the soft portion 41 can be formed of an arbitrary material as long as the volume of the chemical solution storage space 40 can be increased according to the increase or decrease of the chemical solution.
The hard part 42 is not limited to that of the above embodiment as long as it can guide the air bubbles to the outlet 441. For example, the bottom surface 422 may be inclined toward the outlet 441, or the side surfaces 425 may be formed in a linear shape in which the distance between the side surfaces 425 facing each other decreases toward the bottom surface 422.
The cover part 43 is not limited to that of the above embodiment, and for example, the cover part 43 may be formed so as to cover only the upper part of the soft part 41, or the side surface 435 may be formed in a rectangular tube shape.
The liquid feeding part 44 may not be configured to be fitted in the fitting hole 424 of the hard part 42, and may be integrally formed with the hard part 42 by injection molding, extrusion molding, blow molding or the like.
The overfill detection unit 45 and the full-fill detection unit 46 can employ any configuration capable of detecting overfill or full-fill. For example, a limit switch or a piezoelectric element can be used, and overfilling or full filling may be detected by a potential change when the soft part 41 presses the limit switch or the piezoelectric element. In addition, the electrode pads 452 and 462 may not be provided in the soft part 41. For example, the cover part 43 supports the electrode pads 452 and 462 so as to be close to and away from the electrodes 451 and 461. Also good.
　薬液ポンプ５では、図１１Ａおよび図１１Ｂに示すように、第１弁座７１１および第２弁座７３１に突状部としての複数の突起７１５、７３５を設け、当該複数の突起７１５、７３５を傘部５６２、５７２に沿って環状に配置してもよい。この際、各突起７１５、７３５を各弁座７１１、７３１における傘部５６２、５７２の基端近傍の位置に、すなわち各弁座７１１、７３１の凹部７１２の外縁部に設ければ、傘部５６２、５７２と弁座７１１、７３１との間のデッドボリュームを効果的に低減することができる。
　また、突起７１５、７３５を各弁座７１１、７３１の凹部７１２の外縁部に沿って連続した環状に形成してもよい。
　さらに、ピストン５５は、駆動部５８以外の駆動機器で駆動してもよいし、手動で駆動してもよい。
　さらに、第１逆止弁５６および第２逆止弁５７の一方が、リフト式やボール式等の他の種類の逆止弁であってもよい。 In the chemical pump 5, as shown in FIGS. 11A and 11B, the first valve seat 711 and the second valve seat 731 are provided with a plurality of protrusions 715 and 735 as projecting portions, and the plurality of protrusions 715 and 735 are umbrellas. You may arrange | position circularly along the part 562,572. At this time, if the projections 715 and 735 are provided at positions near the base ends of the umbrella portions 562 and 572 in the valve seats 711 and 731, that is, at the outer edge portions of the recesses 712 of the valve seats 711 and 731, the umbrella portions 562. , 572 and the valve seats 711, 731 can be effectively reduced.
Further, the protrusions 715 and 735 may be formed in a continuous ring shape along the outer edge of the recess 712 of each valve seat 711 and 731.
Furthermore, the piston 55 may be driven by a drive device other than the drive unit 58 or may be driven manually.
Furthermore, one of the first check valve 56 and the second check valve 57 may be another type of check valve such as a lift type or a ball type.
　投与に用いる薬液としては、任意のものを使用することができ、例えば、インスリン、各種ホルモン、モルヒネ等の鎮痛薬、抗炎症剤等を使用することができる。 As the drug solution used for administration, any drug can be used. For example, insulin, various hormones, analgesics such as morphine, anti-inflammatory agents and the like can be used.
　本発明は、使用者に薬液を投与する薬液投与装置に利用できる他、他の医療用ポンプおよび当該医療用ポンプを備えた医療器具に利用できる。 The present invention can be used for a medical solution administration device that administers a chemical solution to a user, as well as other medical pumps and medical devices equipped with the medical pump.
　　１　　　薬液投与装置
　　４　　　薬液容器
　　５　　　薬液ポンプ
　　４０　　薬液収容空間
　　４１　　軟質部
　　４２　　硬質部
　　４２３　窪み
　　４２６　充填口
　　４２８　傾斜面
　　４４１　流出口
　　４４２　突出部
  DESCRIPTION OF SYMBOLS 1 Chemical solution administration apparatus 4 Chemical solution container 5 Chemical solution pump 40 Chemical solution storage space 41 Soft part 42 Hard part 423 Depression 426 Filling port 428 Inclined surface 441 Outflow port 442 Protrusion part

Claims (6)

  1. 　薬液投与装置に用いられる薬液容器であって、
    　変形可能な軟質部と、
    　所定の形状を有し、前記軟質部とともに薬液収容空間を形成する硬質部と、
    　前記硬質部に設けられ、前記薬液収容空間から薬液が流出する流出口とを備えていることを特徴とする薬液容器。     A chemical solution container used in a chemical solution administration device,
    A deformable soft part;
    A hard part having a predetermined shape and forming a medical solution containing space together with the soft part;
    A chemical solution container provided with an outflow port which is provided in the hard part and from which the chemical solution flows out from the chemical solution storage space.
  2. 　請求項１に記載の薬液容器において、
    　前記薬液収容空間に前記薬液を充填するための充填口を備え、
    　前記充填口は、前記薬液収容空間に対して前記流出口と同じ側に設けられていることを特徴とする薬液容器。     The chemical solution container according to claim 1,
    A filling port for filling the chemical solution storage space with the chemical solution;
    The chemical liquid container, wherein the filling port is provided on the same side as the outflow port with respect to the chemical liquid storage space.
  3. 　請求項２に記載の薬液容器において、
    　前記充填口は、当該充填口を上方に向けたときに前記流出口よりも下方の位置に設けられていることを特徴とする薬液容器。     The chemical solution container according to claim 2,
    The filling container is provided at a position below the outflow port when the filling port is directed upward.
  4. 　請求項１から請求項３のいずれかに記載の薬液容器において、
    　前記硬質部における前記薬液収容空間に臨む位置には、前記薬液収容空間から離間する方向に傾斜した傾斜面を有する窪みが設けられ、
    　前記流出口は、前記窪み内に設けられていることを特徴とする薬液容器。     In the chemical | medical solution container in any one of Claims 1-3,
    At the position facing the chemical solution storage space in the hard portion, a recess having an inclined surface inclined in a direction away from the chemical solution storage space is provided,
    The chemical solution container, wherein the outflow port is provided in the recess.
  5. 　請求項１から請求項４のいずれかに記載の薬液容器において、
    　前記流出口の周囲には、前記薬液収容空間に向けて突出した突出部が設けられていることを特徴とする薬液容器。     In the chemical | medical solution container in any one of Claims 1-4,
    Around the outflow port, a protruding portion that protrudes toward the chemical solution storage space is provided.
  6. 　請求項１から請求項５のいずれかに記載の薬液容器と、
    　前記薬液容器から薬液を送出する薬液ポンプとを備えていることを特徴とする薬液投与装置。
          The chemical solution container according to any one of claims 1 to 5,
    A chemical solution administration device comprising: a chemical solution pump for delivering a chemical solution from the chemical solution container.
PCT/JP2014/058828 2013-04-02 2014-03-27 Medical solution container and medical solution administration device WO2014162971A1 (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09500291A (en) * 1993-05-28 1997-01-14 サイエンス インコーポレイテッド Fluid supply device
JP3127020B2 (en) * 1990-11-29 2001-01-22 ミニメッド・インコーポレーテッド Pharmaceutical infusion pump, pressure reservoir and method of using the same
JP2001515371A (en) * 1995-10-11 2001-09-18 サイエンス インコーポレイテッド Drug delivery device with bolus injection site

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3127020B2 (en) * 1990-11-29 2001-01-22 ミニメッド・インコーポレーテッド Pharmaceutical infusion pump, pressure reservoir and method of using the same
JPH09500291A (en) * 1993-05-28 1997-01-14 サイエンス インコーポレイテッド Fluid supply device
JP2001515371A (en) * 1995-10-11 2001-09-18 サイエンス インコーポレイテッド Drug delivery device with bolus injection site

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