WO2014147080A2 - Wirkstoff-beladene biokompatible polyelektrolyt-multischichten auf basis sulfatierter glykosaminoglykane, verfahren zur herstellung der multischichten und deren verwendung - Google Patents

Wirkstoff-beladene biokompatible polyelektrolyt-multischichten auf basis sulfatierter glykosaminoglykane, verfahren zur herstellung der multischichten und deren verwendung Download PDF

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Publication number
WO2014147080A2
WO2014147080A2 PCT/EP2014/055430 EP2014055430W WO2014147080A2 WO 2014147080 A2 WO2014147080 A2 WO 2014147080A2 EP 2014055430 W EP2014055430 W EP 2014055430W WO 2014147080 A2 WO2014147080 A2 WO 2014147080A2
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WO
WIPO (PCT)
Prior art keywords
pll
polyelectrolyte
layer
optionally
poly
Prior art date
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PCT/EP2014/055430
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German (de)
English (en)
French (fr)
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WO2014147080A3 (de
Inventor
Steffi Grohmann
Gerhard Hildebrand
Klaus Liefeith
Original Assignee
Institut Für Bioprozess- Und Analysenmesstechnik E. V.
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Application filed by Institut Für Bioprozess- Und Analysenmesstechnik E. V. filed Critical Institut Für Bioprozess- Und Analysenmesstechnik E. V.
Publication of WO2014147080A2 publication Critical patent/WO2014147080A2/de
Publication of WO2014147080A3 publication Critical patent/WO2014147080A3/de

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/34—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3821—Bone-forming cells, e.g. osteoblasts, osteocytes, osteoprogenitor cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
    • A61L2300/406—Antibiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412—Tissue-regenerating or healing or proliferative agents
    • A61L2300/414—Growth factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/606—Coatings
    • A61L2300/608—Coatings having two or more layers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2420/00—Materials or methods for coatings medical devices
    • A61L2420/08—Coatings comprising two or more layers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • Cell Biology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Zoology (AREA)
  • Botany (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Materials For Medical Uses (AREA)
  • Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PCT/EP2014/055430 2013-03-18 2014-03-18 Wirkstoff-beladene biokompatible polyelektrolyt-multischichten auf basis sulfatierter glykosaminoglykane, verfahren zur herstellung der multischichten und deren verwendung WO2014147080A2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102013204742.8A DE102013204742A1 (de) 2013-03-18 2013-03-18 Wirkstoff-beladene biokompatible Polyelektrolyt-Multischichten auf Basis sulfatierter Glykosaminoglykane, Verfahren zur Herstellung der Multischichten und deren Verwendung
DE102013204742.8 2013-03-18

Publications (2)

Publication Number Publication Date
WO2014147080A2 true WO2014147080A2 (de) 2014-09-25
WO2014147080A3 WO2014147080A3 (de) 2014-12-11

Family

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Family Applications (1)

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PCT/EP2014/055430 WO2014147080A2 (de) 2013-03-18 2014-03-18 Wirkstoff-beladene biokompatible polyelektrolyt-multischichten auf basis sulfatierter glykosaminoglykane, verfahren zur herstellung der multischichten und deren verwendung

Country Status (2)

Country Link
DE (1) DE102013204742A1 (3Den)
WO (1) WO2014147080A2 (3Den)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110214176A (zh) * 2016-12-15 2019-09-06 格勒诺布尔理工学院 通过聚电解质多层膜涂覆多孔板的机器人方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008157372A2 (en) 2007-06-14 2008-12-24 Massachusetts Institute Of Technology Self assembled films for protein and drug delivery applications
WO2010081888A1 (de) 2009-01-15 2010-07-22 EMS Elektro Metall Schwanenmühle GmbH Graphitelektrode mit elektrischem anschlussstück

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10300167B2 (en) * 2006-03-24 2019-05-28 Cabertech, Inc. Functionalized calcium phosphate artificial bone and joint compositions and methods of use and manufacture
DE102010003615A1 (de) * 2010-04-01 2011-10-06 Leibniz-Institut Für Polymerforschung Dresden E.V. Verfahren zur Herstellung eines Drug-Delivery-Systems auf der Basis von Polyelektrolytkomplexen

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008157372A2 (en) 2007-06-14 2008-12-24 Massachusetts Institute Of Technology Self assembled films for protein and drug delivery applications
WO2010081888A1 (de) 2009-01-15 2010-07-22 EMS Elektro Metall Schwanenmühle GmbH Graphitelektrode mit elektrischem anschlussstück

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
A. TEZCANER ET AL., BIOMACROMOLECULES, vol. 7, no. 1, 2006, pages 86 - 94
CROUZIER, T.; T. BOUDOU ET AL., CURRENT OPINION IN COLLOID & INTERFACE SCIENCE, vol. 15, no. 6, 2010, pages 417 - 426
GROHMANN, S.; H. ROTHE ET AL., BIOMACROMOLECULES, vol. 12, no. 6, 2011, pages 1987 - 1997
REN, K.; T. CROUZIER ET AL., ADV. FUNCT. MATER., vol. 18, 2008, pages 1378 - 1389
RICHERT, L.; P. LAVALLE ET AL., BIOMACROMOLECULES, vol. 3, no. 6, 2002, pages 1170 - 1178

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110214176A (zh) * 2016-12-15 2019-09-06 格勒诺布尔理工学院 通过聚电解质多层膜涂覆多孔板的机器人方法
CN110214176B (zh) * 2016-12-15 2023-08-08 格勒诺布尔理工学院 通过聚电解质多层膜涂覆多孔板的机器人方法

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Publication number Publication date
DE102013204742A1 (de) 2014-09-18
WO2014147080A3 (de) 2014-12-11

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WO2014147080A2 (de) Wirkstoff-beladene biokompatible polyelektrolyt-multischichten auf basis sulfatierter glykosaminoglykane, verfahren zur herstellung der multischichten und deren verwendung

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