WO2014143375A1 - Extraits de serrisa japonica et procédés d'utilisation - Google Patents

Extraits de serrisa japonica et procédés d'utilisation Download PDF

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Publication number
WO2014143375A1
WO2014143375A1 PCT/US2014/010051 US2014010051W WO2014143375A1 WO 2014143375 A1 WO2014143375 A1 WO 2014143375A1 US 2014010051 W US2014010051 W US 2014010051W WO 2014143375 A1 WO2014143375 A1 WO 2014143375A1
Authority
WO
WIPO (PCT)
Prior art keywords
skin
extract
composition
improvement
amount
Prior art date
Application number
PCT/US2014/010051
Other languages
English (en)
Inventor
Qian Zheng
John W. Lyga
Uma Santhanam
Permanan Raaj KHUSIAL
Ying Chen
Original Assignee
Avon Products, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US13/793,109 external-priority patent/US9034396B2/en
Application filed by Avon Products, Inc. filed Critical Avon Products, Inc.
Publication of WO2014143375A1 publication Critical patent/WO2014143375A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9789—Magnoliopsida [dicotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations

Definitions

  • the present invention relates generally to cosmetic compositions incorporating Serrisa japonica extracts and their use to reduce fine lines and wrinkles, improve sagging, enhance lifting, improve skin tone and lighten discolorations of the skin and to improve the overall appearance of skin by increasing epidermal thickness, reducing melanin production, and stimulating the production of collagen, hyaluronic acid, and/or by inducing lipogenesis.
  • compositions comprising and extract of Serrisa japonica may stimulate lipid production ("lipogenesis") in the skin.
  • lipogenesis lipid production
  • Such compositions will be particularly suitable for the treatment and prevention of the loss of subcutaneous fat, and in particular, facial fat loss, sagging skin, wrinkles, dry skin, and the like.
  • compositions incorporating Serrisa japonica extracts are used to lighten, i.e. reduce the pigmentation, of hair, skin, lips, and/or nails to achieve the following lightening benefits:
  • the term "lightening” is meant herein to refer to any detectable reduction in skin color/pigmentation of hair, skin, lips, and/or nails, e.g., a reduction visible to the naked eye, that occurs after contacting the skin of an individual with a treatment regimen comprising a Serrisa japonica extract. As an example, this may refer to a evening or optimization of a discoloration of the skin, i.e. bleaching age spots, freckles, efc.to reduce or eliminate the color difference between the discoloration and the surrounding skin; and/or an overall lightening of the individual's normal pigmentation/skin color, i.e. skin lightening.
  • reducing pigmentation means the complete prevention, control of secretion, or a degree of reduction of the formation of melanin, respectively.
  • prevention refers to affording skin not yet affected by the condition a benefit that serves to avoid, delay, forestall, minimize, or reduce the recurrence/ onset of one or more unwanted features associated with the skin condition to be prevented.
  • Such preventative benefits include, for example, delaying development and/or recurrence of the condition, or reducing the duration, severity, or intensity of one or more unwanted features associated with the condition if it eventually develops.
  • wrinkle refers to both fine wrinkling and coarse wrinkling.
  • Fine wrinkling or fine lines refers to superficial lines and wrinkles on the skin surface.
  • Coarse wrinkling refers to deep furrows, particularly deep lines/wrinkles on the face and around the eyes, including expression lines such as frown lines and wrinkles, forehead lines and wrinkles, crow's feet lines and wrinkles, nasolabial fold and marionette lines and wrinkles.
  • Forehead lines and wrinkles refer to superficial lines and/or deep furrows on skin of the forehead.
  • Crow's feet lines and wrinkles refer to superficial lines and/or deep furrows on skin around the eye area.
  • Marionette lines and wrinkles refer to superficial lines and/or deep furrows on skin around the mouth. Wrinkles can be assessed for number, length, and depth of the lines.
  • the cosmetic compositions used in the method of the current invention comprise a botanical component derived from the Serrisa japonica plant.
  • Serrisa japonica plant may be in any form including, but not limited to, the whole plant, a dried plant, a ground plant or parts thereof, including but not limited to, seeds, needles, leaves, roots, bark, cones, stems, rhizomes, callus cells, protoplasts, organs and organ systems, and meristems, an extract, a dried extract, a synthetic extract, or components and/or constituents found in, or isolated from, the plant, and/or portions of the plant, or extracts derived either directly or synthetically from the plant, or any combinations thereof.
  • the vehicle may comprise an aqueous phase, an oil phase, an alcohol, a silicone phase or mixtures thereof.
  • the cosmetically acceptable vehicle may also comprise an emulsion.
  • suitable emulsions include water-in- oil emulsions, oil-in-water emulsions, silicone-in-water emulsions, water-in-silicone emulsions, wax-in-water emulsions, water-oil -water triple emulsions or the like having the appearance of a cream, gel or microemulsions.
  • the emulsion may include an emulsifier, such as a nonionic, anionic or amphoteric surfactant.
  • Hydrocarbon oils include those having 6-20 carbon atoms, more in one embodiment 10-16 carbon atoms.
  • Representative hydrocarbons include decane, dodecane, tetradecane, tridecane, and Cs-2o isoparaffins.
  • Paraffinic hydrocarbons are available from Exxon under the ISOPARS trademark, and from the Permethyl Corporation.
  • C 8 -2o paraffinic hydrocarbons such as d 2 isoparaffin (isododecane) manufactured by the Permethyl Corporation having the tradename Permethyl 99ATM are also contemplated to be suitable.
  • Various commercially available Ci6 isoparaffins, such as isohexadecane (having the tradename Permethyl®) are also suitable.
  • water-in-silicone emulsifiers include, without limitation, PEG/PPG-18/18 dimethicone (trade name 5225C, Dow Corning), PEG/PPG-19/19 dimethicone (trade name BY25-337, Dow Corning), Cetyl PEG/PPG-10/1 dimethicone (trade name Abil EM-90, Goldschmidt Chemical Corporation), PEG-12 dimethicone (trade name SF 1288, General Electric), lauryl PEG/PPG-18/18 methicone (trade name 5200 FORMULATION AID, Dow Corning), PEG-12 dimethicone crosspolymer (trade name 9010 and 901 1 silicone elastomer blend, Dow Corning), PEG-10 dimethicone crosspolymer (trade name KSG-20, Shin-Etsu), dimethicone PEG-10/15 crosspolymer (trade name KSG-210, Shin-Etsu), and dimethicone PEG-7 isostearate.
  • the water-in-silicone emulsifiers typically will be present in the composition in an amount from about 0.001 % to about 10% by weight, in particular in an amount from about 0.01 % to about 5% by weight, and more in one embodiment, below 1 % by weight.
  • compositions may include liposomes.
  • the liposomes may comprise other additives or substances and/or may be modified to more specifically reach or remain at a site following administration.
  • the present compositions may also include skin whiteners.
  • suitable skin whiteners include, but are not limited to, one or more of the following: ascorbyl glucoside, vitamin C, retinol and/or its derivatives, arbutin, bearberry extract, rumex crispus extract, milk proteins including hydrolyzed milk proteins, N,N,S-tris(carboxym- ethyl)cysteamine, oleanolic acids, perilla oil, placenta extract, Saxifragia sarmentosa, perilla extract, juniperic acid, TDPA, Ligusticum chiangxiong heart., Asmunda japonica thunb., Stellaria medica (L.) cyr., Sedum sarmentosum bunge, Ligusticum lucidum Ait., ilex purpurea hassk, emblica, apigenin, ascorbyl palmitol, car
  • the topical compositions of the present invention may also include one or more of the following: a skin penetration enhancer, an emollient, a skin plumper, an optical diffuser, a sunscreen, an exfoliating agent, and an antioxidant.
  • a skin plumper serves as a collagen enhancer to the skin.
  • An example of a suitable and in one embodiment skin plumper is palmitoyi oligopeptide.
  • Other skin plumpers are collagen and/or other glycosaminoglycan (GAG) enhancing agents.
  • the skin plumper may comprise from about 0.1 wt % to about 20 wt % of the total weight of the composition.
  • sunscreens are those with a broad range of UVB and UVA protection, such as octocrylene, avobenzone (Parsol 1789), octyl methoxycinnamate, octyl salicylate, oxybenzone, homosylate, benzophenone, camphor derivatives, zinc oxide, and titanium dioxide.
  • the sunscreen may comprise from about 0.01 wt % to about 70 wt % of the composition.
  • antioxidants functions, among other things, to scavenge free radicals from skin to protect the skin from environmental aggressors.
  • antioxidants that may be used in the present compositions include compounds having phenolic hydroxy functions, such as ascorbic acid and its derivatives/esters; alpha-hydroxyacids; beta-carotene; catechins; curcumin; ferulic acid derivatives (e.g.
  • the cosmetic compositions can further comprise at least one collagen and/or elastin stimulator.
  • collagen or elastin stimulators are effective in, for example, providing improvement in procollagen and/or collagen production and/or improvement in maintenance and remodeling of elastin.
  • Colorants may include, for example, organic and inorganic pigments and pearlescent agents.
  • Suitable inorganic pigments include, but are not limited to, titanium oxide, zirconium oxide, and cerium oxide, as well as zinc oxide, iron oxide, chromium oxide and ferric blue.
  • Suitable organic pigments include barium, strontium, calcium, aluminium lakes and carbon black.
  • Suitable pearlescent agents include mica coated with titanium oxide, iron oxide, or natural pigments.
  • the composition may comprise at least one additional botanical, such as, for example, a botanical extract, an essential oil, or the plant itself.
  • Suitable botanicals include, without limitation, extracts from Abies pindrow, Acacia catechu, Anogeissus latifolia, Asmunda japonica, Azadirachta indica, Butea frondosa, Butea monosperma, Cedrus deodara, Emblica officinalis, Ficus benghalensis, Glycyrrhiza glabra, Ilex purpurea Hassk, Inula racemosa, Ligusticum chuangxiong, Ligusticum lucidum, Mallotus philippinensis, Mimusops elengi, Morinda citrifolia, Moringa oleifera, Naringi crenulata, Nerium indicum, Psoralea corylifolia, Stenoloma chus
  • a composition comprising an extract of Serrisa japonica is topically applied to an "individual in need thereof," by which is meant an individual that stands to benefits from reducing visible signs of skin damage or aging.
  • the Serrisa japonica extract is provided in a pharmaceutically, physiologically, cosmetically, and dermatologically-acceptable vehicle, diluent, or carrier, where the composition is topically applied to an affected area of skin and left to remain on the affected area in an amount effective for improving the condition and aesthetic appearance of skin.
  • methods for treating fine lines and wrinkles comprise topically applying the inventive compositions comprising a Serrisa japonica extract to the skin of an individual in need thereof, e.g., topically application directly to the fine line and/or wrinkle in an amount and for a time sufficient to reduce the severity of the fine lines and/or wrinkles or to prevent or inhibit the formation of new fine lines and/or wrinkles.
  • the effect of a composition on the formation or appearance of fine lines and wrinkles can be evaluated qualitatively, e.g., by visual inspection, or quantitatively, e.g., by microscopic or computer assisted measurements of wrinkle morphology (e.g., the number, depth, length, area, volume and/or width of wrinkles per unit area of skin).
  • This embodiment includes treatment of wrinkles on the skin of the hands, arms, legs, neck, chest, and face, including the forehead.
  • TDPA Thiodipropionic acid

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Cosmetics (AREA)

Abstract

L'invention concerne des procédés d'utilisation d'extraits de Serrisa japonica pour conférer des bienfaits à la peau et/ou améliorer des états de peau résultant du vieillissement ou d'une peau endommagée.
PCT/US2014/010051 2013-03-11 2014-01-02 Extraits de serrisa japonica et procédés d'utilisation WO2014143375A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13/793,109 2013-03-11
US13/793,109 US9034396B2 (en) 2012-12-11 2013-03-11 Serissa japonica extracts and methods of use

Publications (1)

Publication Number Publication Date
WO2014143375A1 true WO2014143375A1 (fr) 2014-09-18

Family

ID=51537487

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2014/010051 WO2014143375A1 (fr) 2013-03-11 2014-01-02 Extraits de serrisa japonica et procédés d'utilisation

Country Status (1)

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WO (1) WO2014143375A1 (fr)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7959953B2 (en) * 2003-10-10 2011-06-14 Access Business Group International Llc Cosmetic composition and methods
US8048456B2 (en) * 2009-08-28 2011-11-01 Mary Kay Inc. Skin care formulations
US20120282194A1 (en) * 2011-03-28 2012-11-08 Tiffany Florence Topical skin care formulations comprising plant extracts

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7959953B2 (en) * 2003-10-10 2011-06-14 Access Business Group International Llc Cosmetic composition and methods
US8048456B2 (en) * 2009-08-28 2011-11-01 Mary Kay Inc. Skin care formulations
US20120282194A1 (en) * 2011-03-28 2012-11-08 Tiffany Florence Topical skin care formulations comprising plant extracts

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
AUSTRALIAN NATIONAL DATA SERVICE.: "Australian Organism Collection.", October 2012 (2012-10-01), pages 1, Retrieved from the Internet <URL:http://rda.ebi.edu.au/default.jsp?collectionld=4993> [retrieved on 20040831] *

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