WO2014137993A1 - Procédés pour capteur d'absorbance sans étalonnage permettant de mesurer le ph et le pco2 - Google Patents

Procédés pour capteur d'absorbance sans étalonnage permettant de mesurer le ph et le pco2 Download PDF

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Publication number
WO2014137993A1
WO2014137993A1 PCT/US2014/020159 US2014020159W WO2014137993A1 WO 2014137993 A1 WO2014137993 A1 WO 2014137993A1 US 2014020159 W US2014020159 W US 2014020159W WO 2014137993 A1 WO2014137993 A1 WO 2014137993A1
Authority
WO
WIPO (PCT)
Prior art keywords
sensor molecule
absorbance
sensor
equation
acid
Prior art date
Application number
PCT/US2014/020159
Other languages
English (en)
Inventor
David Reed Markle
Original Assignee
David Reed Markle
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by David Reed Markle filed Critical David Reed Markle
Publication of WO2014137993A1 publication Critical patent/WO2014137993A1/fr

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/78—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
    • G01N21/80—Indicating pH value

Abstract

La présente invention concerne un procédé comprenant l'éclairage, avec une lumière à large bande, d'une molécule de détection disposée en contact fonctionnel avec un analyte. La molécule de détection peut se lier de manière réversible à l'analyte. Le procédé comprend en outre la mesure de l'absorbance de la lumière transmise à travers la molécule de détection à deux longueurs d'onde différentes pour déterminer une première valeur d'absorbance et une seconde valeur d'absorbance. Le procédé comprend en outre le calcul d'un rapport entre la première valeur d'absorbance et la seconde valeur d'absorbance, et le calcul de la concentration de l'analyte au moins en partie sur la base du rapport.
PCT/US2014/020159 2013-03-04 2014-03-04 Procédés pour capteur d'absorbance sans étalonnage permettant de mesurer le ph et le pco2 WO2014137993A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361772201P 2013-03-04 2013-03-04
US61/772,201 2013-03-04

Publications (1)

Publication Number Publication Date
WO2014137993A1 true WO2014137993A1 (fr) 2014-09-12

Family

ID=51491842

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2014/020159 WO2014137993A1 (fr) 2013-03-04 2014-03-04 Procédés pour capteur d'absorbance sans étalonnage permettant de mesurer le ph et le pco2

Country Status (1)

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WO (1) WO2014137993A1 (fr)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6197534B1 (en) * 1998-07-17 2001-03-06 Joseph R. Lakowicz Engineered proteins for analyte sensing
US20020001851A1 (en) * 2000-01-31 2002-01-03 Degrandpre Michael D. Calibration-free optical chemical sensors
US20090018418A1 (en) * 2007-05-10 2009-01-15 Glumetrics, Inc. Equilibrium non-consuming fluorescence sensor for real time intravascular glucose measurement
US20120214250A1 (en) * 2011-02-18 2012-08-23 Tokyo Women's Medical University Method and apparatus for measuring ph of solution

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6197534B1 (en) * 1998-07-17 2001-03-06 Joseph R. Lakowicz Engineered proteins for analyte sensing
US20020001851A1 (en) * 2000-01-31 2002-01-03 Degrandpre Michael D. Calibration-free optical chemical sensors
US20090018418A1 (en) * 2007-05-10 2009-01-15 Glumetrics, Inc. Equilibrium non-consuming fluorescence sensor for real time intravascular glucose measurement
US20120214250A1 (en) * 2011-02-18 2012-08-23 Tokyo Women's Medical University Method and apparatus for measuring ph of solution

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