WO2014127351A3 - Compositions et procédés pour modifier la fermentation microbienne intestinale en utilisant des bactéries réduisant les sulfates - Google Patents

Compositions et procédés pour modifier la fermentation microbienne intestinale en utilisant des bactéries réduisant les sulfates Download PDF

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Publication number
WO2014127351A3
WO2014127351A3 PCT/US2014/016883 US2014016883W WO2014127351A3 WO 2014127351 A3 WO2014127351 A3 WO 2014127351A3 US 2014016883 W US2014016883 W US 2014016883W WO 2014127351 A3 WO2014127351 A3 WO 2014127351A3
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WO
WIPO (PCT)
Prior art keywords
sulfate
methods
compositions
microbial fermentation
reducing bacteria
Prior art date
Application number
PCT/US2014/016883
Other languages
English (en)
Other versions
WO2014127351A2 (fr
Inventor
Federico E. Rey
Mark Gonzalez
Jeffrey I. Gordon
Original Assignee
Washington University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Washington University filed Critical Washington University
Priority to US14/768,394 priority Critical patent/US20160000837A1/en
Priority to EP14751570.4A priority patent/EP2956152A4/fr
Publication of WO2014127351A2 publication Critical patent/WO2014127351A2/fr
Publication of WO2014127351A3 publication Critical patent/WO2014127351A3/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/30—Dietetic or nutritional methods, e.g. for losing weight
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K2035/11—Medicinal preparations comprising living procariotic cells
    • A61K2035/115—Probiotics

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Dermatology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

La présente invention concerne des combinaisons et des procédés pour modifier la représentation d'au moins une espèce bactérienne réduisant les sulfates dans l'intestin d'un sujet, afin de modifier l'activité de fermentation microbienne dans l'intestin du sujet.
PCT/US2014/016883 2013-02-18 2014-02-18 Compositions et procédés pour modifier la fermentation microbienne intestinale en utilisant des bactéries réduisant les sulfates WO2014127351A2 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US14/768,394 US20160000837A1 (en) 2013-02-18 2014-02-18 Compositions and methods to alter gut microbial fermentation using sulfate-reducing bacteria
EP14751570.4A EP2956152A4 (fr) 2013-02-18 2014-02-18 Compositions et procédés pour modifier la fermentation microbienne intestinale en utilisant des bactéries réduisant les sulfates

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201361765991P 2013-02-18 2013-02-18
US61/765,991 2013-02-18
US201361852221P 2013-03-15 2013-03-15
US61/852,221 2013-03-15

Publications (2)

Publication Number Publication Date
WO2014127351A2 WO2014127351A2 (fr) 2014-08-21
WO2014127351A3 true WO2014127351A3 (fr) 2014-11-06

Family

ID=51354701

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2014/016883 WO2014127351A2 (fr) 2013-02-18 2014-02-18 Compositions et procédés pour modifier la fermentation microbienne intestinale en utilisant des bactéries réduisant les sulfates

Country Status (3)

Country Link
US (1) US20160000837A1 (fr)
EP (1) EP2956152A4 (fr)
WO (1) WO2014127351A2 (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015066625A1 (fr) 2013-11-01 2015-05-07 Washington University Méthodes pour établir et restaurer la fonction normale du microbiote intestinal chez un sujet en ayant besoin
US20150246081A1 (en) * 2014-03-03 2015-09-03 Shayne Kenneth Morris Probiotics with methods for growth and use separately and in combination
US10300043B2 (en) 2015-08-12 2019-05-28 Mayo Foundation For Medical Education And Research Method for treating a gastrointestinal disorder in a mammal using bacteroides thetaiotaomicron and compositions thereof
WO2017184565A1 (fr) 2016-04-20 2017-10-26 The Board Of Trustees Of The Leland Stanford Junior University Compositions et procédés d'expression d'acide nucléique et sécrétion de protéine dans des bactéroïdes
EP3554518A4 (fr) 2016-12-15 2020-07-29 The Board of Trustees of the Leland Stanford Junior University Compositions et procédés pour moduler la croissance d'une cellule bactérienne intestinale génétiquement modifiée
US10695386B2 (en) 2017-05-11 2020-06-30 Shayne K. Morris Skin microbiome colonizer formulations and methods for use
CN111107859B (zh) * 2017-06-14 2022-04-29 4D制药研究有限公司 包含细菌菌株的组合物
JP6943360B2 (ja) * 2017-09-04 2021-09-29 学校法人星薬科大学 アクアポリンを指標とする腸内細菌叢の変化を検出する方法
US20200216787A1 (en) * 2017-09-18 2020-07-09 Dupont Nutrition Biosciences Aps Riboflavinase enzymes and their use to prevent off flavor in brewing
US11168299B2 (en) 2018-04-11 2021-11-09 Shayne Morris Pairing probiotics and prebiotics, methods for growth and use, separately and in combination
US11291696B2 (en) 2018-04-11 2022-04-05 Shayne Morris Pairing probiotics and prebiotics, methods for growth and use, separately and in combination
WO2024005468A1 (fr) * 2022-06-27 2024-01-04 한국과학기술원 Composition pour prévenir ou traiter une tumeur au cerveau dans un environnement à haute teneur en glucose, comprenant un micro-organisme et un inhibiteur de point de contrôle immunitaire en tant que principes actifs

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012122522A2 (fr) * 2011-03-09 2012-09-13 Washington University Mise en culture d'un prélèvement d'une communauté microbienne intestinale

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012122522A2 (fr) * 2011-03-09 2012-09-13 Washington University Mise en culture d'un prélèvement d'une communauté microbienne intestinale

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DATABASE GENBANK [online] 14 March 2001 (2001-03-14), "Desulfovibrio desulfuricans nine-heme cytochrome c operon, complete sequence", XP055276590, accession no. NCBI Database accession no. AF186393 *
DATABASE GENBANK [online] 2 September 2003 (2003-09-02), "Desulfovibrio desulfuricans subsp. desulfuricans qmo gene cluster, complete sequence", XP055276592, accession no. NCBI Database accession no. AY227146 *
DATABASE GENBANK [online] 23 January 2008 (2008-01-23), "Desulfovibrio vulgaris str. 'Miyazaki F' HysA (hysA) and HysB (hysB) genes", XP055276582, accession no. NCBI Database accession no. EU327692 *
GIBSON ET AL.: "Use of a Three-Stage Continuous Culture System to Stody the Effect of Mucin on Dissimilatory Sulfate Reduction and Methanogenesis by Mixed Populations of Human Gut Bacteria", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, vol. 54, no. 11, 10 May 1988 (1988-05-10), pages 2750 - 2755, XP055268549 *

Also Published As

Publication number Publication date
EP2956152A2 (fr) 2015-12-23
WO2014127351A2 (fr) 2014-08-21
US20160000837A1 (en) 2016-01-07
EP2956152A4 (fr) 2016-10-26

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