WO2014111903A3 - A process for the preparation of 6-fluoro-3,4-dihydro-2h-chromene- 2-carbaldehyde - Google Patents
A process for the preparation of 6-fluoro-3,4-dihydro-2h-chromene- 2-carbaldehyde Download PDFInfo
- Publication number
- WO2014111903A3 WO2014111903A3 PCT/IB2014/058437 IB2014058437W WO2014111903A3 WO 2014111903 A3 WO2014111903 A3 WO 2014111903A3 IB 2014058437 W IB2014058437 W IB 2014058437W WO 2014111903 A3 WO2014111903 A3 WO 2014111903A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- chromene
- dihydro
- preparation
- carbaldehyde
- fluoro
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/66—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
The present invention relates to a process for ihe preparation of 6-f!uoro-3,4-dihydro- 2H-chromene-2-carbaidehyde which is useful as an Intermediate in the synthesis of Nebivolol or its pharmaceutical acceptable salts.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN184/MUM/2013 | 2013-01-21 | ||
IN184MU2013 | 2013-01-21 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2014111903A2 WO2014111903A2 (en) | 2014-07-24 |
WO2014111903A3 true WO2014111903A3 (en) | 2014-10-23 |
Family
ID=50439425
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/IB2014/058437 WO2014111903A2 (en) | 2013-01-21 | 2014-01-21 | A process for the preparation of 6-fluoro-3,4-dihydro-2h-chromene- 2-carbaldehyde |
Country Status (1)
Country | Link |
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WO (1) | WO2014111903A2 (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110156765A (en) * | 2019-06-09 | 2019-08-23 | 河南师范大学 | The method that the one kettle way that hydrogen bonding functionality ionic liquid promotes prepares 2- amino -4H- chromene derivative |
CN110054607A (en) * | 2019-06-09 | 2019-07-26 | 河南师范大学 | The method for the one pot process 2- amino -3- itrile group -7- hydroxyl -4H- chromene derivative that bursine promotes |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102329291A (en) * | 2011-07-27 | 2012-01-25 | 上海现代制药股份有限公司 | Method for preparing 6-fluoro-3,4-dihydro-2H-1-benzopyran-2-formaldehyde |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3444098A1 (en) | 1984-12-04 | 1986-06-05 | Basf Ag, 6700 Ludwigshafen | METHOD FOR PRODUCING 2- (1-HYDROXYMETHYL) -ACRYLNITRILE AND -ACRYL ESTERS |
CA1337432C (en) | 1988-03-23 | 1995-10-24 | Raymond M. Xhonneux | Method of lowering the blood pressure |
-
2014
- 2014-01-21 WO PCT/IB2014/058437 patent/WO2014111903A2/en active Application Filing
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102329291A (en) * | 2011-07-27 | 2012-01-25 | 上海现代制药股份有限公司 | Method for preparing 6-fluoro-3,4-dihydro-2H-1-benzopyran-2-formaldehyde |
Also Published As
Publication number | Publication date |
---|---|
WO2014111903A2 (en) | 2014-07-24 |
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