WO2014057438A3 - Compositions and methods for treatment of cardiovascular diseases - Google Patents

Compositions and methods for treatment of cardiovascular diseases Download PDF

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Publication number
WO2014057438A3
WO2014057438A3 PCT/IB2013/059238 IB2013059238W WO2014057438A3 WO 2014057438 A3 WO2014057438 A3 WO 2014057438A3 IB 2013059238 W IB2013059238 W IB 2013059238W WO 2014057438 A3 WO2014057438 A3 WO 2014057438A3
Authority
WO
WIPO (PCT)
Prior art keywords
disease
treatment
compositions
diseases
hypertension
Prior art date
Application number
PCT/IB2013/059238
Other languages
French (fr)
Other versions
WO2014057438A2 (en
Inventor
Mahesh Kandula
Original Assignee
Mahesh Kandula
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mahesh Kandula filed Critical Mahesh Kandula
Publication of WO2014057438A2 publication Critical patent/WO2014057438A2/en
Publication of WO2014057438A3 publication Critical patent/WO2014057438A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Abstract

Disclosed are compounds or their pharmaceutical acceptable salts, as well as polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof for the treatment of cardiovascular diseases. The pharmaceutical compositions comprising an effective amount of the compounds may be formulated for oral, buccal, rectal, topical, transdermal, transmucosal, intravenous or parenteral administration, syrup, or injection. Such compositions may be used to the treatment of coronary heart diseases, hypertension, heart failure, inflammatory bowel disease, valvular heart disease, stroke, cerebrovascular disease, peripheral arterial disease, kidney diseases, diabetes related renal complications, hypertension, albuminuria, ESRD, kidney GFR complications, vascular disease and ventricular septal defect.
PCT/IB2013/059238 2012-10-13 2013-10-09 Compositions and methods for the treatment of cardiovascular diseases WO2014057438A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN4284/CHE/2012 2012-10-13
IN4284CH2012 2012-10-13

Publications (2)

Publication Number Publication Date
WO2014057438A2 WO2014057438A2 (en) 2014-04-17
WO2014057438A3 true WO2014057438A3 (en) 2014-07-10

Family

ID=50478010

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2013/059238 WO2014057438A2 (en) 2012-10-13 2013-10-09 Compositions and methods for the treatment of cardiovascular diseases

Country Status (1)

Country Link
WO (1) WO2014057438A2 (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008053331A1 (en) * 2006-11-01 2008-05-08 Pronova Biopharma Norge A/S Alpha-substituted omega-3 lipids that are activators or modulators of the peroxisome proliferators-activated receptor (ppar).

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008053331A1 (en) * 2006-11-01 2008-05-08 Pronova Biopharma Norge A/S Alpha-substituted omega-3 lipids that are activators or modulators of the peroxisome proliferators-activated receptor (ppar).

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
HOLMEIDE A. K. ET AL.: "The syntheses of three highly unsaturated marine lipid hydrocarbons", J. CHEM. SOC., PERKIN TRANS., vol. 1, 24 July 2011 (2011-07-24), pages 1942 - 1946 *
ITOH T. ET AL.: "Efficient Synthesis of the Very-Long-Chain n-3 Fatty Acids, Tetracosahexaenoic Acid (C24:6n-3) and Tricosahexaenoic Acid (C23:6n-3)", LIPIDS, no. 46, 24 February 2011 (2011-02-24), pages 455 - 461 *

Also Published As

Publication number Publication date
WO2014057438A2 (en) 2014-04-17

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