WO2013117751A3 - Méthodes liées au traitement des maladies inflammatoires - Google Patents
Méthodes liées au traitement des maladies inflammatoires Download PDFInfo
- Publication number
- WO2013117751A3 WO2013117751A3 PCT/EP2013/052629 EP2013052629W WO2013117751A3 WO 2013117751 A3 WO2013117751 A3 WO 2013117751A3 EP 2013052629 W EP2013052629 W EP 2013052629W WO 2013117751 A3 WO2013117751 A3 WO 2013117751A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- disorders
- treatment
- inflammatory diseases
- methods related
- inflammatory
- Prior art date
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- General Engineering & Computer Science (AREA)
- Pathology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1020147022156A KR20140124767A (ko) | 2012-02-10 | 2013-02-11 | 염증성 질환 및 장애의 치료에 관한 방법 |
MX2014009490A MX2014009490A (es) | 2012-02-10 | 2013-02-11 | Metodos relacionados con el tratamiento de enfermedades y trastornos inflamatorios. |
EP13704081.2A EP2812445A2 (fr) | 2012-02-10 | 2013-02-11 | Méthodes liées au traitement des maladies inflammatoires |
CA2864133A CA2864133A1 (fr) | 2012-02-10 | 2013-02-11 | Methodes liees au traitement des maladies inflammatoires |
BR112014019274A BR112014019274A2 (pt) | 2012-02-10 | 2013-02-11 | métodos relacionados ao tratamento de doenças e distúrbios inflamatórios |
AU2013217940A AU2013217940A1 (en) | 2012-02-10 | 2013-02-11 | Methods related to treatment of inflammatory diseases and disorders |
CN201380019432.0A CN104204230A (zh) | 2012-02-10 | 2013-02-11 | 治疗炎性疾病和病症的相关方法 |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP12154917.4 | 2012-02-10 | ||
EP12154917 | 2012-02-10 | ||
US201261597924P | 2012-02-13 | 2012-02-13 | |
US61/597,924 | 2012-02-13 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2013117751A2 WO2013117751A2 (fr) | 2013-08-15 |
WO2013117751A3 true WO2013117751A3 (fr) | 2013-10-03 |
Family
ID=48948117
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP2013/052629 WO2013117751A2 (fr) | 2012-02-10 | 2013-02-11 | Méthodes liées au traitement des maladies inflammatoires |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP2812445A2 (fr) |
KR (1) | KR20140124767A (fr) |
CN (1) | CN104204230A (fr) |
AU (1) | AU2013217940A1 (fr) |
BR (1) | BR112014019274A2 (fr) |
CA (1) | CA2864133A1 (fr) |
MX (1) | MX2014009490A (fr) |
WO (1) | WO2013117751A2 (fr) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20240095363A (ko) * | 2016-05-20 | 2024-06-25 | 세다르스-신나이 메디칼 센터 | 유전자에 기반한 염증성 장 질환의 진단 |
CN110244053B (zh) * | 2019-05-09 | 2022-03-11 | 北京大学第三医院(北京大学第三临床医学院) | 用于诊断狼疮肾炎并肺动脉高压疾病的分子标志物及其用途 |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2007006858A2 (fr) * | 2005-07-12 | 2007-01-18 | Oy Jurilab Ltd | Methode de traitement de maladies cardio-vasculaires et du metabolisme et detection des risques associes |
WO2008048986A2 (fr) * | 2006-10-17 | 2008-04-24 | Children's Hospital Medical Center | Technique par batterie de gènes pour prédire la réponse dans les maladies intestinales inflammatoires |
WO2008104608A1 (fr) * | 2007-03-01 | 2008-09-04 | Universite Catholique De Louvain | Procédé pour la détermination et la classification de conditions rhumatismales |
WO2008157282A1 (fr) * | 2007-06-18 | 2008-12-24 | Genentech, Inc. | Marqueurs biologiques prédictifs d'une réponse d'arthrite rhumatoïde à des antagonistes de cellule b |
WO2010113096A1 (fr) * | 2009-03-30 | 2010-10-07 | Tel Hashomer Medical Research Infrastructure And Services Ltd. | Méthodes pour prévoir l'évolution clinique de la sclérose en plaque et la traiter |
US20110091457A1 (en) * | 2009-10-16 | 2011-04-21 | Cornelis Lammert Verweij | Method for prognosticating the clinical response of a patient to b-lymphocyte inhibiting or depleting therapy |
WO2011154139A2 (fr) * | 2010-06-07 | 2011-12-15 | Roche Diagnostics Gmbh | Marqueurs d'expression génique pour la prédiction d'une réponse à un traitement par un médicament anticorps monoclonal inhibant le récepteur de l'interleukine-6 |
Family Cites Families (16)
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AU4713901A (en) | 1999-12-07 | 2001-06-25 | Parthus Technologies Plc | Model for charge pump phase-locked loop |
EP1616575B1 (fr) | 1999-12-23 | 2012-06-06 | ZymoGenetics, Inc. | Methode destinée à traiter l'inflammation |
DE10227527A1 (de) | 2002-06-20 | 2004-01-08 | Clariant Gmbh | Verfahren zur Herstellung von Disazopigmenten |
US7435800B2 (en) | 2003-05-23 | 2008-10-14 | Chi-Mei Medical Center | Antibodies to interleukin-20 and method for inhibiting interleukin-20 induced cell proliferation |
EP2143733A1 (fr) | 2003-11-21 | 2010-01-13 | ZymoGenetics, Inc. | Anticorps du récepteur anti-il-20 et partenaires de liaison et procédés d'utilisation dans l'inflammation |
IES20050495A2 (en) | 2005-07-20 | 2006-11-01 | Minroc Techn Promotions Ltd | A drill bit assembly for fluid-operated percussion drill tools |
WO2007038501A2 (fr) | 2005-09-27 | 2007-04-05 | The Feinstein Institute For Medical Research | Marqueurs de l'arthrite rhumatoide |
WO2007081465A2 (fr) | 2005-12-09 | 2007-07-19 | Chi-Mei Medical Center | Anticorps dirigés contre l'interleukine 20 et procédé d'inhibition de la prolifération cellulaire induite par l'interleukine 20 |
EP1857559A1 (fr) | 2006-05-16 | 2007-11-21 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Méthode de prédiction de la réponse aux agents de blocage de TNF aplha |
WO2008056198A1 (fr) | 2006-11-09 | 2008-05-15 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Procédé permettant de prédire la sensibilité thérapeutique à des agents bloquant le tnf-alpha |
WO2008132176A2 (fr) | 2007-04-27 | 2008-11-06 | Universite Catholique De Louvain | Méthode de prévision de la réponse d'un patient à une thérapie bloquant le tnf |
NZ581742A (en) | 2007-06-08 | 2012-09-28 | Biogen Idec Inc | Biomarkers for predicting anti-tnf responsiveness or non-responsiveness |
RU2011101969A (ru) | 2008-06-30 | 2012-08-10 | Ново Нордиск А/С (DK) | Антитела к человеческому интерлейкину-20 |
AU2009285585A1 (en) | 2008-08-28 | 2010-03-04 | Wyeth Llc | Uses of IL-22, IL-17, and IL-1 family cytokines in autoimmune diseases |
RU2015132478A (ru) | 2009-03-05 | 2015-12-10 | Эббви Инк. | Связывающие il-17 белки |
EP3211094A3 (fr) | 2009-09-03 | 2017-11-01 | F. Hoffmann-La Roche AG | Procédés pour traiter, diagnostiquer, et surveiller la polyarthrite rhumatoïde |
-
2013
- 2013-02-11 MX MX2014009490A patent/MX2014009490A/es unknown
- 2013-02-11 AU AU2013217940A patent/AU2013217940A1/en not_active Withdrawn
- 2013-02-11 KR KR1020147022156A patent/KR20140124767A/ko not_active Application Discontinuation
- 2013-02-11 EP EP13704081.2A patent/EP2812445A2/fr not_active Withdrawn
- 2013-02-11 WO PCT/EP2013/052629 patent/WO2013117751A2/fr active Application Filing
- 2013-02-11 CA CA2864133A patent/CA2864133A1/fr not_active Withdrawn
- 2013-02-11 CN CN201380019432.0A patent/CN104204230A/zh not_active Withdrawn
- 2013-02-11 BR BR112014019274A patent/BR112014019274A2/pt not_active IP Right Cessation
Patent Citations (7)
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WO2007006858A2 (fr) * | 2005-07-12 | 2007-01-18 | Oy Jurilab Ltd | Methode de traitement de maladies cardio-vasculaires et du metabolisme et detection des risques associes |
WO2008048986A2 (fr) * | 2006-10-17 | 2008-04-24 | Children's Hospital Medical Center | Technique par batterie de gènes pour prédire la réponse dans les maladies intestinales inflammatoires |
WO2008104608A1 (fr) * | 2007-03-01 | 2008-09-04 | Universite Catholique De Louvain | Procédé pour la détermination et la classification de conditions rhumatismales |
WO2008157282A1 (fr) * | 2007-06-18 | 2008-12-24 | Genentech, Inc. | Marqueurs biologiques prédictifs d'une réponse d'arthrite rhumatoïde à des antagonistes de cellule b |
WO2010113096A1 (fr) * | 2009-03-30 | 2010-10-07 | Tel Hashomer Medical Research Infrastructure And Services Ltd. | Méthodes pour prévoir l'évolution clinique de la sclérose en plaque et la traiter |
US20110091457A1 (en) * | 2009-10-16 | 2011-04-21 | Cornelis Lammert Verweij | Method for prognosticating the clinical response of a patient to b-lymphocyte inhibiting or depleting therapy |
WO2011154139A2 (fr) * | 2010-06-07 | 2011-12-15 | Roche Diagnostics Gmbh | Marqueurs d'expression génique pour la prédiction d'une réponse à un traitement par un médicament anticorps monoclonal inhibant le récepteur de l'interleukine-6 |
Non-Patent Citations (7)
Title |
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JULIÀ ANTONIO ET AL: "Identification of candidate genes for rituximab response in rheumatoid arthritis patients by microarray expression profiling in blood cells", PHARMACOGENOMICS, FUTURE MEDICINE LTD, UK, vol. 10, no. 10, 1 October 2009 (2009-10-01), pages 1697 - 1708, XP009160425, ISSN: 1744-8042 * |
LEQUERRÉ THIERRY ET AL: "Gene profiling in white blood cells predicts infliximab responsiveness in rheumatoid arthritis", ARTHRITIS RESEARCH AND THERAPY, BIOMED CENTRAL, LONDON, GB, vol. 8, no. 4, 3 July 2006 (2006-07-03), pages R105, XP021020585, ISSN: 1478-6354, DOI: 10.1186/AR1924 * |
NAKADA S ET AL: "Identification of candidate genes involved in endogenous protection mechanisms against acute pancreatitis in mice", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC. ORLANDO, FL, US, vol. 391, no. 3, 15 January 2010 (2010-01-15), pages 1342 - 1347, XP026854448, ISSN: 0006-291X, [retrieved on 20100114], DOI: 10.1016/J.BBRC.2009.12.047 * |
SARCHIELLI P ET AL: "Fibroblast growth factor-2 levels are elevated in the cerebrospinal fluid of multiple sclerosis patients", NEUROSCIENCE LETTERS, LIMERICK, IE, vol. 435, no. 3, 25 April 2008 (2008-04-25), pages 223 - 228, XP022655800, ISSN: 0304-3940, [retrieved on 20080226], DOI: 10.1016/J.NEULET.2008.02.040 * |
SEKIGUCHI N ET AL: "Messenger ribonucleic acid expression profile in peripheral blood cells from RA patients following treatment with an anti-TNF-alpha monoclonal antibody, infliximab", RHEUMATOLOGY, OXFORD UNIVERSITY PRESS, LONDON, GB, vol. 47, no. 6, 1 June 2008 (2008-06-01), pages 780 - 788, XP002562468, ISSN: 1462-0324, DOI: 10.1093/RHEUMATOLOGY/KEN083 * |
SIRPA LEIVO-KORPELA ET AL: "Adipokine resistin predicts anti-inflammatory effect of glucocorticoids in asthma", JOURNAL OF INFLAMMATION, vol. 8, no. 1, 1 January 2011 (2011-01-01), pages 12, XP055030042, ISSN: 1476-9255, DOI: 10.1186/1476-9255-8-12 * |
TANINO M ET AL: "Prediction of efficacy of anti-TNF biologic agent, infliximab, for rheumatoid arthritis patients using a comprehensive transcriptome analysis of white blood cells", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC. ORLANDO, FL, US, vol. 387, no. 2, 18 September 2009 (2009-09-18), pages 261 - 265, XP026434615, ISSN: 0006-291X, [retrieved on 20090703], DOI: 10.1016/J.BBRC.2009.06.149 * |
Also Published As
Publication number | Publication date |
---|---|
EP2812445A2 (fr) | 2014-12-17 |
KR20140124767A (ko) | 2014-10-27 |
MX2014009490A (es) | 2014-08-29 |
CN104204230A (zh) | 2014-12-10 |
AU2013217940A1 (en) | 2014-07-31 |
WO2013117751A2 (fr) | 2013-08-15 |
BR112014019274A2 (pt) | 2017-06-27 |
CA2864133A1 (fr) | 2013-08-15 |
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