WO2013060220A1 - Dispositif 4d de radiothérapie à positionnement stéréoscopique - Google Patents

Dispositif 4d de radiothérapie à positionnement stéréoscopique Download PDF

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Publication number
WO2013060220A1
WO2013060220A1 PCT/CN2012/082348 CN2012082348W WO2013060220A1 WO 2013060220 A1 WO2013060220 A1 WO 2013060220A1 CN 2012082348 W CN2012082348 W CN 2012082348W WO 2013060220 A1 WO2013060220 A1 WO 2013060220A1
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WIPO (PCT)
Prior art keywords
accelerator
axis rotating
axis
bracket
rotating bracket
Prior art date
Application number
PCT/CN2012/082348
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English (en)
Chinese (zh)
Inventor
姚毅
Original Assignee
苏州雷泰医疗科技有限公司
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Publication of WO2013060220A1 publication Critical patent/WO2013060220A1/fr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1077—Beam delivery systems
    • A61N5/1081—Rotating beam systems with a specific mechanical construction, e.g. gantries
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/44—Constructional features of apparatus for radiation diagnosis
    • A61B6/4429—Constructional features of apparatus for radiation diagnosis related to the mounting of source units and detector units
    • A61B6/4435—Constructional features of apparatus for radiation diagnosis related to the mounting of source units and detector units the source unit and the detector unit being coupled by a rigid structure
    • A61B6/4447—Tiltable gantries

Definitions

  • the present invention relates to a medical device, and more particularly to a 4D stereotactic radiotherapy apparatus for use with an accelerator treatment device. Background technique
  • the doctor or physicist When radiotherapy is performed on a tumor (target area), precise positioning of the tumor is required.
  • the doctor or physicist first scans the patient's CT image in the CT room and reconstructs a series of CT images into a three-dimensional image by algorithm. At this time, the three-dimensional coordinates of the tumor in the three-dimensional image can be located.
  • the doctor or physicist places the patient in the accelerator chamber for a reset, precisely matching the three-dimensional coordinates of the tumor to the accelerator's treatment center (i socenter). Finally start treatment.
  • the accelerator of the current radiotherapy equipment can only rotate around the Z axis, and the radiation emitted by the accelerator can only be limited to the plane perpendicular to the Z axis, and the angle of incidence cannot be freely selected, which greatly restricts the examination of the disease and the treatment of the directional irradiation. .
  • the prior art proposes a solution in which the accelerator is suspended on a slide rail parallel to the Z-axis and can slide back and forth.
  • the accelerator head can swing on the YZ plane, and the accelerator rotates in the XY plane with the accelerator bracket. With the oscillation of the YZ plane, three-dimensional multi-angle illumination is realized.
  • the suspension and drive structure are very complicated and costly.
  • the accelerator swing causes the radiation to be unstable, and the accelerator transmission system is closely connected with the accelerator. It may also cause interference to the treatment system, making the manufacturing difficulty and cost increase.
  • the accelerator cannot maintain the corresponding working state with the digital image detecting plate during the swinging process, so the treatment effect cannot be detected at any time, and further correction and treatment are performed. . Summary of the invention
  • an object of the present invention is to provide a 4D stereotactic radiography that can track the time axis of a tumor by tracking in a 4D space, achieve accurate treatment, has a simple structure, is difficult to manufacture, and saves time and cost. Therapeutic device.
  • a 4D stereotactic radiotherapy apparatus including an accelerator, further comprising: an accelerator bracket, an X-axis rotating device for driving the accelerator bracket to rotate around the X-axis, and a machine wood,
  • the accelerator bracket includes an X-axis rotating bracket and a Z-axis rotating bracket, and the Z-axis rotating bracket is disposed on the X-axis rotating bracket and rotatable around a central axis thereof, that is, a Z-axis; the X-axis rotating bracket and the The frame is connected by the X-axis rotating device, or the X-axis rotating bracket is directly movably connected to the frame;
  • the accelerator is at least one;
  • the accelerator is mounted on the X-axis rotating bracket, and the Z-axis rotating bracket transmission is disposed on the X-axis rotating bracket and can rotate around the central axis, that is, the Z-axis;
  • the X-axis rotating bracket is drivingly connected to the frame through the X-axis rotating device; or the X-axis rotating bracket is directly movably connected to the frame, and is drivingly connected with the X-axis rotating device, the frame
  • the base and two struts fixed to the base are included, or the frame is two struts directly fixed to the ground, and the accelerator bracket is suspended from the two struts.
  • the X-axis rotating device comprises two sets of gear transmissions and an X-axis driving component for driving the gear transmission, the X-axis rotating device is fixedly connected to the pillar of the frame, the X-axis A rotating bracket is fixedly coupled to the output shaft of the gearbox.
  • the X-axis rotating device comprises a hydraulic device, a screw pushing device or a pneumatic device, and the hydraulic device, the screw pushing device or the pneumatic device is hingedly connected to the frame base or the ground at one end, and the other end is hingedly connected to the Said on the X-axis rotating bracket.
  • the X-axis rotating device includes an arc-shaped rack fixedly disposed on the base of the frame or directly disposed on the ground, and a gear disposed on the X-axis rotating bracket and meshing with the curved rack .
  • the accelerator is at least one KV level accelerator
  • the 4D stereotactic radiotherapy apparatus further comprises at least one KV level digital image detecting plate for detecting KV level energy and imaging;
  • the Z-axis rotating bracket is provided with an isocenter annular rail, and the annular rail is two segments a symmetrical arc-shaped guide rail, or a continuous arc;
  • the KV-class accelerator and the KV-class digital image detecting plate are mounted on the annular guide rail and slidable along the same.
  • the accelerator is at least one MV-level accelerator
  • the 4D stereotactic radiotherapy apparatus further includes at least one MV-level digital image detecting plate
  • the MV-level accelerator is fixedly mounted on the Z-axis rotating bracket. And rotate with it;
  • the MV-level digital image detecting plate is mounted on the ⁇ -axis rotating bracket and rotates therewith, or the MV-level digital image detecting plate is mounted on the isometric guide rail or the guiding groove provided on the cymbal rotating bracket And can move back and forth along the isometric guide rail or the guide groove while rotating the bracket with the rotation of the shaft.
  • the accelerator is at least one MV-level accelerator
  • the 4D stereotactic radiotherapy apparatus further includes at least one MV-level digital image detecting plate
  • the MV-level accelerator is fixedly mounted on the x-axis rotating bracket. And rotate with it;
  • the MV-level digital image detecting plate is mounted on the yoke rotating bracket and rotates therewith, or the MV-level digital image detecting plate is mounted on the isocenter guide or guide groove provided on the 1-axis rotating bracket And can move back and forth along the isometric guide rail or the guide groove while rotating the bracket with the rotation of the shaft.
  • the KV level accelerators are three.
  • the MV level digital image detecting tablet is fixed, folded or telescopic.
  • the MV-level accelerator is further provided with a grating for controlling the area and shape through which the rays pass.
  • Cone beam CT based on large-area amorphous silicon digital X-ray detector plate developed in recent years has the characteristics of small size, light weight and open architecture, which can be directly integrated into the linear accelerator.
  • the CT image can be acquired and reconstructed within one volume by rotating the rack for one revolution.
  • the reconstructed 3D patient model of the CT image within this volume can be compared to the patient model of the treatment plan and the parameters to be adjusted for the treatment bed are obtained.
  • there are two types namely: kV. CBCT and kV-level X-rays.
  • KV-CBCT The combination of the reading device and the detector of the flat panel detector has the advantage of improving the spatial resolution. Therefore, the kV-CBCT can achieve higher spatial resolution than the conventional CT, and the density resolution. It is also sufficient to distinguish the soft tissue structure, which can be guided by the tumor itself to guide radiotherapy. Moreover, the system has high radiation utilization efficiency and the patient receives a small dose of radiation, making it a real-time monitoring tool. Therefore, CBCT has multiple functions for X-ray fluoroscopy, radiography and volume imaging at the treatment site, which is valuable for online reset and has become a hot spot for IGRT development and application. However, the density resolution, especially the low contrast density resolution, is different from the advanced CT ratio.
  • MV-CBCT Poul iot uses low-dose MV. CBCT to obtain three-dimensional images without pulse artifacts, fusion plan kV CT images, and position correction, push tube and nasopharyngeal fusion to 1 Nakagawa, etc. - CBCT performs online calibration.
  • the x-ray source of MV. CBCT and the therapeutic beam homolog are its advantages.
  • the MVx line has the characteristics of less side scatter and is suitable for evaluating accurate electron density, so it can be used as a dosimetry monitoring device at the same time.
  • kv. CBCT it is at a significant disadvantage in image resolution, signal-to-noise ratio, and imaging dose.
  • the time-variation factor is added to the CT scan and the accelerator, it is called four dimens iona radiotherapy (4DRT), and the CT scan with the time variable factor is added.
  • Four-dimensional CT (four dimens i ona 1 computed tomography, 4DCT) 4DCT scan captures CT scan sequences of patients at different times in a certain period of time, and the images are reconstructed by phase to obtain 3D images of tumors and vital organs over time. The sequence of changes. 4DCT was used to simulate the localization, and the 3D image of the tumor or vital organ obtained by CBCT was compared with the 3D image of the 4DCT sequence, and the accelerator was controlled for real-time illumination to complete 4DRT.
  • the dynamic spiral tomography (hei ca l tomotherapy) system is an intensity-modulated radiotherapy system that combines treatment planning, dose calculation, mega-level CT scan, localization and spiral irradiation treatment functions.
  • CT-like mode the tumor is irradiated from a 360-degree focusing tomography, the target area is well-formed, the dose distribution is uniform, and the normal tissues and organs are protected to the maximum extent; the image-guided radiotherapy function is used, and the treatment machine is used before each radiotherapy.
  • Image Guided Radiation Therapy is a four-dimensional radiotherapy technique that incorporates the concept of time factor based on three-dimensional radiotherapy technology, taking into account the movement of anatomical tissue during treatment and the displacement error between fractionated treatments. , such as respiratory and peristaltic movements, daily placement error, target area contraction, etc., which cause changes in the distribution of radiation doses and effects on treatment plans, etc., using advanced imaging equipment to treat tumors before and during treatment.
  • 3D is the concept of space, which is the space consisting of three axes: X, Y, and .. 4D According to Einstein's theory, the concept of time is added. Thus, the combination of time and space becomes the so-called 4D space.
  • TPS Radiation Therapy Planning System
  • the blades move uninterrupted from one end to the other to control the shape and size of the rays emitted by the accelerator.
  • the accelerator bracket includes an X-axis rotation for mounting the accelerator a bracket and a Z-axis rotating bracket, wherein the Z-axis rotating bracket is disposed on the X-axis rotating bracket and rotatable around a central axis thereof, that is, a Z-axis;
  • the X-axis rotating bracket is drivingly connected to the frame through the X-axis rotating device; or the X-axis rotating bracket is directly movably connected to the frame and is drivingly connected to the X-axis rotating device.
  • the accelerator can follow the accelerator bracket to perform the nodding and tilting movements, that is, the irradiation angle of the ray emitted by the accelerator relative to the z-axis can be changed, so that the illumination angle can only be changed in the two-dimensional plane, and can be changed in
  • the three-dimensional adjustment greatly increases the degree of freedom of adjustment and provides greater support for accurate detection and treatment.
  • the frame includes a base and two pillars fixed to the base, or the frame is two pillars directly fixed to the ground, and the accelerator bracket is suspended from the two pillars, two
  • the struts are designed to make the accelerator head's head and nodding (ie, rotating around the X axis) more convenient.
  • This program enables pure KV-class radiotherapy equipment to achieve 4D dynamic treatment, and the cost is effectively controlled, providing ideal medical equipment for small and medium-sized hospitals that cannot afford expensive MV-class equipment.
  • the solution can integrate the MV-level accelerator, and maintain the working posture corresponding to the digital image detecting tablet at any time in the three-dimensional operation, and can perform the detection and tracking of the therapeutic effect at any time, and perform real-time correction, verification and treatment.
  • FIG. 1 is a schematic view of Embodiment 1 of a 4D stereotactic radiotherapy apparatus according to the present invention
  • FIG. 2 is a schematic view of Embodiments 2 and 3 of a 4D stereotactic radiotherapy apparatus according to the present invention
  • FIG. 3 is a 4D stereoscopic positioning of the present invention.
  • Figure 4 is a schematic view of a third embodiment of a 4D stereotactic radiotherapy apparatus according to the present invention
  • Figure 5 is a schematic view of an embodiment of a 4D stereotactic radiotherapy apparatus according to the present invention; It is a schematic diagram of Embodiment 4 of a 4D stereotactic radiotherapy apparatus according to the present invention.
  • the names of the corresponding parts represented by numbers and letters in the figure:
  • MV-level accelerator 22 MV-level digital image detection tablet 31.
  • KV-class accelerator 32 KV-level digital image Detection plate specific implementation
  • a 4D stereotactic radiotherapy apparatus includes an MV-level accelerator 21, and further includes: an accelerator bracket, an X-axis rotating device 13 that drives the accelerator bracket to rotate about the X-axis, and a frame 1;
  • An adapter on the cymbal rotating bracket 14 (which may also be integrated on the accelerator), the MV stage accelerator 21 is mounted on the adapter.
  • the adapter is not shown in the drawings, it is fixedly mounted (or detachably movable, or drive mounted) on the cymbal swivel bracket 14, which can also be integrally formed with the MV-level accelerator 21, or assembled as a whole. .
  • the accelerator bracket includes an X-axis rotating bracket 11 and a cymbal rotating bracket 14 .
  • the cymbal rotating bracket 14 is disposed on the X-axis rotating bracket 11 and can rotate around a central axis thereof, that is, 1 axis; the 4D
  • the stereotactic radiotherapy apparatus further includes a MV level digital image detecting plate 22 for detecting MV level energy and imaging, the MV level digital image detecting plate 11 being mounted on the x-axis rotating bracket 14, the MV level digital image detecting tablet 22 is fixed, folded or telescopic.
  • the cymbal rotating bracket 14 is provided with an annular guide rail 12, which is composed of two symmetrical circular arc guide rails;
  • the 4D stereotactic radiotherapy apparatus further includes two KV-level digital image detecting plates 32 that are respectively mounted on the circular arc-shaped guide rails of the annular guide rail 12 and can be scanned along the KV-level energy and imaged, and two A KV-class accelerator 31 (here, an X-ray emitting device) mounted on and slidable on the different arc-shaped guide rails of the annular guide 12.
  • KV-level digital image detecting plates 32 that are respectively mounted on the circular arc-shaped guide rails of the annular guide rail 12 and can be scanned along the KV-level energy and imaged
  • a KV-class accelerator 31 here, an X-ray emitting device mounted on and slidable on the different arc-shaped guide rails of the annular guide 12.
  • the X-axis rotating bracket 11 and the cymbal rotating bracket 14 are slidably connected by an annular guide rail or an annular sliding groove, and an annular face gear is arranged on the X-axis rotating bracket 11 or the cymbal rotating bracket 14 to rotate on the y-axis.
  • a servo motor and a transmission gear matched with the annular face gear are disposed on the bracket 14 or the X-axis rotating bracket 11.
  • the cymbal rotating bracket 14 rotates about its central longitudinal axis ( ⁇ axis) to achieve the MV level.
  • the accelerator 21, the MV-level numerical image detecting plate 22, and the annular guide 12 and the KV-class accelerator 31 and the KV-class digital image detecting plate 32 mounted thereon are used for the purpose of center-rotation around the yoke.
  • the X-axis rotating bracket 11 is drivingly coupled to the frame 1 through the X-axis rotating device 13, and an adapter disposed on the cymbal rotating bracket 14, and the MV-level accelerator 21 is mounted on the adapter.
  • the X-axis rotating device 13 includes a gear transmission and an X-axis driving component that drives the gear transmission, and the X-axis rotating device is fixedly coupled to the frame 1 as shown in FIG.
  • the X-axis rotating bracket 11 is fixedly coupled to the output shaft of the gearbox, so that the entire accelerator bracket is suspended from the two pillars, thereby implementing the nodding and tilting functions for the entire accelerator bracket. (that is, rotating around the X axis) laid the foundation.
  • the accelerator bracket (the X-axis rotating bracket 11) can be driven to reciprocate around the X-axis, that is, the accelerator bracket and the MV-level accelerator 21 are actuated to complete the upward or nod movement.
  • the accelerator can follow the accelerator bracket for nodding and upward movement, that is, the angle of illumination of the ray emitted by the accelerator relative to the Z axis can be changed, so that the illumination angle can be changed only in the two-dimensional plane, and can be changed in three-dimensional space. Adjustments greatly increase the freedom of adjustment and provide greater support for accurate detection and treatment.
  • Two KV level accelerators 31 are respectively used corresponding to the two KV level digital image detecting plates 32, and the MV level accelerator 21 is used correspondingly to the MV level digital image detecting board 22, and the positional relationship is as shown in Fig. 1.
  • a grating that controls the area and shape through which the accelerator rays pass.
  • the grating is an electric multi-blade grating.
  • At least one camera is also disposed on the grating. Neither is shown in the figure.
  • two KV-level accelerators 31 and two KV-level digital image detecting plates 32 respectively correspond to the two ends of the same diameter of the annular guide 12, and the KV-level accelerator 31 and KV are utilized.
  • the level digital image detecting plate 32 cooperates to realize the KV energy level 4D CBCT function.
  • the KV-class accelerator 31 and the KV-class digital image detecting plate 32 are always maintained in a relatively orthogonal position and are rotated around the circular guide 12 in an isocenter, while the KV-level accelerator 31 performs KV-level energy irradiation on the target region (tumor), KV
  • the level digital image detecting plate 32 receives the irradiation dose and generates a series of images according to the capture interval (capture int erva l), which are calculated by software to generate a stereoscopic image of the patient's patient part, which is convenient for accurate diagnosis of the condition.
  • the MV-level digital image detecting plate 22 and the MV-level accelerator 2 1 are respectively located at the same diameter of both ends of the annular guide 12, and the MV-level digital image detecting plate 11 is used together with the MV-level energy of the MV-level accelerator 21. It can replace the expensive special dose verification products currently available on the market and realize the radiation therapy dose verification (Dos ime t ry ) function.
  • the MV-level digital image detecting panel 22 captures the MV-level energy-irradiated image of the MV-level accelerator 21, the software converts the image-recorded grayscale value into a dose value and compares and verifies the dose in the design plan.
  • Regular verification of MV-level accelerator 21, TPS (radiation therapy planning system), and electric multi-leaf grating can be performed.
  • Two cameras are mounted on the electric multi-leaf grating, looking at the target area (tumor) from the BEV perspective, real-time monitoring and recording of the respiratory motion (rate, trajectory, position) of the target area, peristaltic motion, daily placement error, target area Information such as shrinkage, feedback through software processing, and 4D Track i ng function.
  • the MV-level digital image detecting plate 22 and the MV-level accelerator 2 1 are placed in an orthogonal position.
  • the camera monitors and records the above information and performs feedback, and the MV-level digital image detection is performed.
  • the tablet 22 continuously captures a series of MV-level images, and also feeds the position information of the target area to the software system, compares, registers and corrects the information recorded by the camera, and then controls the movement of the electric multi-blade grating blades through software. It is matched with the motion of the target zone to achieve the I GRT function.
  • a KV-level accelerator 31 and a KV-level digital image detecting tablet 32 are integrated, and a three-dimensional image of the patient is quickly obtained by the CBCT function.
  • the software quickly locates the tumor coordinates in the set of data by an algorithm.
  • the 4D plan is designed in the Radiotherapy Planning System (TPS), and thus the condition can be quickly diagnosed.
  • the 4D plan is transmitted to the control system of the device after the irradiation dose is calculated, and the control grating and the MV level accelerator 21 are treated.
  • the grating blade continuously performs regular round-trip sliding (sl id ing) in the time period according to the planned given position to follow the respiratory motion of the tumor.
  • the main digital image detecting plate 22 is placed orthogonally with the MV level accelerator 21.
  • the MV level accelerator 21 will accurately illuminate the tumor, and during the treatment, the MV level digital image detecting plate 22 is acquired at a fixed frequency.
  • a series of digital images containing dose-gray values eg, one image per 2 s
  • transmitted to the validation software for comparison with the ideal dose calculated by the 4D program for more accurate dose verification results .
  • Detection mode single exposure, double exposure, and treatment sequence exposure mode.
  • the KV level digital image detecting plate 32 and the KV level accelerator 31 may have only one pair, and the MV level digital image detecting plate 11 may also use the same KV level digital image.
  • the detecting plate 32 is concurrently controlled, and the KV-level digital image detecting plate 32 is controlled by the control circuit to correspond to the KV-level accelerator 31 or the MV-level accelerator 11 respectively when necessary to complete the corresponding work.
  • the number of the above devices can also be flexibly configured as needed.
  • the MV-level digital image detecting plate can also be mounted on the isocenter guide rail or the guide groove provided on the 1-axis rotating bracket, and can rotate along the center along with the Z-axis rotating bracket.
  • the rails or guides are moved back and forth so that they can also be controlled and moved to avoid interference between the devices or to achieve more maneuverability.
  • the rest is the same as Embodiment 1, except that the X-axis rotating device is a hydraulic device, and one end of the hydraulic device is hingedly connected to the base of the frame 1 (when the machine is When the rack has only two pillars fixed directly to the ground, the hydraulic device is directly mounted on the ground, and the other end is hingedly connected to the accelerator bracket.
  • the action of the accelerator head and the head 22 of the accelerator bracket and the accelerator 22 are pushed by the piston rod of the hydraulic device, and the accelerator bracket (essentially the X-axis rotating bracket 11) and the frame 1 are movably connected by the rotating shaft and the bearing, also
  • the connection can be made by means of a shaft and a bushing.
  • the above hydraulic device can also be replaced by a screw pushing device or a pneumatic device.
  • the rest is the same as Embodiment 1, except that the X-axis rotating device includes an arc-shaped rack fixed to the base of the frame (when the frame has only two When the struts are directly fixed to the ground, they are directly disposed on the ground, and the gears are disposed on the accelerator bracket and mesh with the curved rack.
  • the gear which can be driven by the servo motor
  • the gear moves up and down along the curved entry, and the accelerator bracket and the accelerator are driven to complete the movement of the head and the nod.
  • an accelerator bracket an X-axis rotating device and a frame that drive the accelerator bracket to rotate around the Z-axis and the X-axis, respectively, and an adapter disposed on the accelerator bracket, the accelerator being mounted on the Above the adapter, the accelerator bracket is drivingly coupled to the frame by the X-axis rotating device.
  • the accelerator can follow the accelerator bracket for nodding and tilting, that is, the angle of the radiation emitted by the accelerator relative to the 1 axis can be changed, so that the illumination angle can be changed only in the two-dimensional plane, and can be changed to Adjustment in three-dimensional space greatly increases the degree of freedom of adjustment, providing greater support for accurate detection and treatment.
  • the annular guide rail on the 1-axis rotating bracket 14 may also be a continuous circular arc-shaped guide rail, as shown in Fig. 5, which can be set as needed.
  • the rest is the same as Embodiment 1, except that the accelerator of this embodiment is three KV-level X-ray emitting devices (ie, KV-level accelerator 31), and is combined with three KV-level digital image detection.
  • the flat plates 32 (or 1 or 2) are mounted on the isocenter circular slide rails and can be controlled to slide freely.
  • This solution enables the pure KV-class radiotherapy equipment to realize the function of 4D dynamic therapy, and the cost is effectively controlled. , providing ideal medical equipment for small and medium-sized hospitals that cannot afford to buy expensive MV-class equipment.
  • the number of KV-level accelerators may also be two, four, etc., and the number of digital image detecting plates of the KV level may be one, two, and the like.
  • the KV level digital image detecting plate 32 and the KV level digital image detecting plate 32 can be controlled to slide on the annular guide 12 or rotate together with the Z-axis rotating bracket 14. Control is very flexible and convenient.
  • the KV level digital image detecting plate 32, the KV level digital image detecting plate 32, and the camera can be determined to adopt one, two or three or other numbers as needed.
  • an X-ray emitting device ie, a KV-level accelerator
  • a KV-level digital image detecting tablet are integrated on the device, and a three-dimensional image of the patient is quickly obtained by the CBCT function.
  • the software uses the algorithm to group the data.
  • the tumor coordinates are quickly located at the isocenter; due to the unique structure of the technical solution, CBCT only needs to rotate 120 degrees to quickly obtain the patient's three-dimensional image, which takes a very short time, so it can be obtained in a time period.
  • the tumor position (registration) of multiple sets of three-dimensional images is compared by an algorithm, according to the image group.
  • the difference in displacement is designed in the Radiation Therapy Planning System (TPS) to design a 4D plan.
  • TPS Radiation Therapy Planning System
  • the 4D plan is transmitted to the grating and the accelerator for treatment after the irradiation dose is calculated.
  • the grating blades are given according to the planned position, in the time week During the period, regular regular sliding is performed to follow the respiratory movement of the tumor. The treatment accuracy is greatly improved, and the damage to normal tissues is reduced.
  • MV-level accelerators or KV-level accelerators may be used to form a simple MV-level or KV-level treatment system, or any number of the two may be matched to meet different needs.
  • the accelerator bracket includes an X-axis rotation for mounting the accelerator a bracket and a cymbal rotating bracket, wherein the cymbal rotating bracket is disposed on the X-axis rotating bracket and rotatable around a central axis thereof, that is, a cymbal; the X-axis rotating bracket and the rack pass the X a shaft rotation device drive connection; or an X-axis rotation bracket directly movably coupled to the frame and drivingly coupled to the X-axis rotation device, the frame including a base and two pillars fixed to the base, or The frame is two pillars directly fixed to the ground, and the accelerator bracket is suspended from the two pillars.
  • the accelerator can follow the accelerator bracket to perform the nodding and tilting movements, that is, the angle of the radiation emitted by the accelerator relative to the x-axis can be changed, so that the illumination angle can only be changed in the two-dimensional plane, and can be changed in
  • the three-dimensional adjustment greatly increases the degree of freedom of adjustment, and provides greater support for accurate detection and treatment.
  • the two-pillar scheme makes the elevation and nodding of the accelerator bracket (ie, rotating around the X-axis) convenient.
  • This program enables pure KV-class radiotherapy equipment to achieve 4D dynamic diagnosis and auxiliary treatment functions, and the cost is effectively controlled, providing ideal medical equipment for small and medium-sized hospitals that cannot afford expensive MV-class equipment.
  • the solution can integrate the MV-level accelerator, and maintain the working posture corresponding to the digital image detecting tablet at any time during the three-dimensional operation, and can perform the detection and tracking of the therapeutic effect at any time, and perform real-time correction, verification and treatment.

Abstract

L'invention concerne un dispositif de radiothérapie à positionnement stéréoscopique, comportant : un accélérateur (21), un support d'accélérateur, un dispositif (13) de rotation sur l'axe X servant à entraîner le support d'accélérateur en rotation autour d'un axe X et un bâti (1), ainsi qu'un adaptateur disposé sur le support d'accélérateur. L'accélérateur (21) est installé au-dessus de l'adaptateur, et le support d'accélérateur et le bâti (1) sont en liaison de transmission par l'intermédiaire du dispositif (13) de rotation sur l'axe X, de sorte que l'accélérateur (21) peut effectuer des actions d'inclinaison vers le bas et vers le haut en suivant le support d'accélérateur, modifiant ainsi l'angle d'irradiation d'un rayon émis par l'accélérateur (21) par rapport à un axe Z. De ce fait, l'angle d'irradiation peut être réglé dans l'espace tridimensionnel, plutôt que d'être simplement modifié dans le plan bidimensionnel comme à l'origine, améliorant ainsi nettement le degré de liberté du réglage, ce qui apporte une assistance renforcée pour une détection et un traitement précis.
PCT/CN2012/082348 2011-10-25 2012-09-28 Dispositif 4d de radiothérapie à positionnement stéréoscopique WO2013060220A1 (fr)

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CN201110327627.4 2011-10-25
CN201110327627 2011-10-25
CN201110447735.5 2011-12-29
CN201110447735.5A CN103071241B (zh) 2011-10-25 2011-12-29 立体定位放射治疗装置

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