WO2013059168A3 - Espirito santo virus and methods for detecting and preventing infection with the same - Google Patents

Espirito santo virus and methods for detecting and preventing infection with the same Download PDF

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Publication number
WO2013059168A3
WO2013059168A3 PCT/US2012/060377 US2012060377W WO2013059168A3 WO 2013059168 A3 WO2013059168 A3 WO 2013059168A3 US 2012060377 W US2012060377 W US 2012060377W WO 2013059168 A3 WO2013059168 A3 WO 2013059168A3
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WO
WIPO (PCT)
Prior art keywords
esv
virus
detecting
methods
same
Prior art date
Application number
PCT/US2012/060377
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French (fr)
Other versions
WO2013059168A2 (en
Inventor
Raquel Hernandez
Dennis T. Brown
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Research Development Foundation
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Publication date
Application filed by Research Development Foundation filed Critical Research Development Foundation
Publication of WO2013059168A2 publication Critical patent/WO2013059168A2/en
Publication of WO2013059168A3 publication Critical patent/WO2013059168A3/en

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011—Details
    • C12N2720/10011—Birnaviridae
    • C12N2720/10021—Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011—Details
    • C12N2720/10011—Birnaviridae
    • C12N2720/10022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011—Details
    • C12N2720/10011—Birnaviridae
    • C12N2720/10061—Methods of inactivation or attenuation
    • C12N2720/10063—Methods of inactivation or attenuation by chemical treatment
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2999/00—Further aspects of viruses or vectors not covered by groups C12N2710/00 - C12N2796/00 or C12N2800/00
    • C12N2999/005—Biological teaching, e.g. a link between protein and disease, new virus causing pandemic

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

A new Birnavirus, Espirito Santo Virus (ESV), is described. The RNA and polynucleotide sequences encoding ESV are disclosed. In certain aspects, methods for detecting ESV and reagents for the same are provided. Also provided are anti-ESV antibodies and antigenic compositions comprising ESV and polypeptides therefrom.
PCT/US2012/060377 2011-10-21 2012-10-16 Espirito santo virus and methods for detecting and preventing infection with the same WO2013059168A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161550129P 2011-10-21 2011-10-21
US61/550,129 2011-10-21

Publications (2)

Publication Number Publication Date
WO2013059168A2 WO2013059168A2 (en) 2013-04-25
WO2013059168A3 true WO2013059168A3 (en) 2013-08-01

Family

ID=48141605

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2012/060377 WO2013059168A2 (en) 2011-10-21 2012-10-16 Espirito santo virus and methods for detecting and preventing infection with the same

Country Status (1)

Country Link
WO (1) WO2013059168A2 (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030191169A1 (en) * 2001-12-07 2003-10-09 Sandino Ana Maria Methods for increasing the survival of aquatic and other animals exposed to an aquatic virus, birnavirus or other RNA virus and compositions for such methods
WO2011054995A2 (en) * 2009-11-06 2011-05-12 Chimera Pharma, S. L. U. PROPHYLACTIC FLU VACCINES FROM VIRAL CAPSIDS OF BIRNAVIRUS CONTAINING THE M2e ANTIGEN OF THE FLU VIRUS
US20110190164A1 (en) * 2008-05-09 2011-08-04 Thomas Zurcher Chimeric fusion proteins and virus like particles from birnavirus vp2

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030191169A1 (en) * 2001-12-07 2003-10-09 Sandino Ana Maria Methods for increasing the survival of aquatic and other animals exposed to an aquatic virus, birnavirus or other RNA virus and compositions for such methods
US20100204290A1 (en) * 2001-12-07 2010-08-12 Diagnotec, Laboratoria Gam Ltda. Procedure for operating a particle filter arranged in an exhaust fume area of a brennkraftmaschine and device to execute the procedure
US20110190164A1 (en) * 2008-05-09 2011-08-04 Thomas Zurcher Chimeric fusion proteins and virus like particles from birnavirus vp2
WO2011054995A2 (en) * 2009-11-06 2011-05-12 Chimera Pharma, S. L. U. PROPHYLACTIC FLU VACCINES FROM VIRAL CAPSIDS OF BIRNAVIRUS CONTAINING THE M2e ANTIGEN OF THE FLU VIRUS

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DATABASE GENBANK 16 June 1999 (1999-06-16), "Drosophila x virus polyprotein gene, complete cds", accession no. 60650.1 *
PHILIP S. SHWEDA ET AL.: "Birnavirus VP1 Proteins Form a Distinct Subgroup of RNA-Dependent RNA Polymerases Lacking a GDD Motif.", VIROLOGY., vol. 296, no. 2, 2002, pages 241 - 250, XP004467201 *

Also Published As

Publication number Publication date
WO2013059168A2 (en) 2013-04-25

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