WO2013057883A1 - Drug container, and drug-filled container in which drug is sealed therein - Google Patents

Abstract

This drug container is provided with a drug-housing chamber (1) having a drug supply port (2), and a drug adjustment chamber (4) connected to the drug-housing chamber (1) via a drug adjustment channel (3). A vacuum port (5) is connected to the drug adjustment chamber (4). The drug adjustment channel (3) is provided with an opening/closing valve (6). When adjusting the amount of a drug (11) remaining in the drug-housing chamber (1), the opening/closing valve (6) is opened, and the surplus of the drug (11) is moved to the drug adjustment chamber (4) by removing air from the vacuum port (5).

Description

Drug container and drug-filled container containing the drug

The present invention relates to a medicine container and a medicine container containing the medicine.

For example, a drug container used for infusion treatment is configured by flowing a drug from a drug supply port into a drug storage chamber.
At the time of infusion treatment, an infusion needle is connected to the medicine supply port via a tube, and the infusion needle is inserted into the patient, whereby the medicine in the medicine storage chamber is administered to the patient (for example, see Patent Document 1 below). .

JP 2004-290217 A

Here, the amount of medicine stored in the medicine storage room needs to be set to an appropriate amount depending on the physique and age of the patient. For this reason, in a drug room, for example, a drug required for each individual is aspirated by an injection needle from an individual drug bottle and injected into a drug storage chamber of a drug container for each individual. . That is, at this time, it takes a lot of work such as taking out the medicine bottle, sucking and injecting the injection needle, storing the medicine bottle, and discarding the injection needle.

Then, an object of this invention is to provide the chemical | medical agent container which can improve workability | operativity, and the chemical | medical agent container which enclosed the chemical | medical agent.
In order to achieve the above object, the drug container includes a drug storage chamber, a drug adjustment chamber, a drug adjustment path, a suction port, and an on-off valve. The medicine storage chamber has a medicine supply port. The medicine adjustment room adjusts the medicine stored in the medicine storage room and has a fixed shape. The medicine adjustment path connects the medicine storage room and the medicine adjustment room. The suction port is connected to the medicine adjustment chamber. The on-off valve is provided in the medicine adjustment path.

The drug container includes a drug adjustment chamber, a drug administration port, and a drug stirring unit. The drug adjustment chamber stores the solution. The medicine storage chamber is connected to the medicine adjustment chamber via a medicine supply path and stores the medicine. The drug administration port is connected to the drug adjustment room. The drug stirring unit is connected to the drug adjusting chamber and can store a stirring bar therein.
The method of using the drug container includes a plurality of drug storage chambers, a plurality of drug supply passages connected to each of the plurality of drug storage chambers, and a drug connected to the plurality of drug supply paths via open / close valves. The on-off valve switches the open / close state of each medicine storage chamber and medicine supply port in the order of (1) to (5) below.
(1) Closed state (2) First drug storage chamber and drug supply port open state (3) Second drug storage chamber and drug supply port open state (4) N (where N is 2 (Natural number above) The drug storage chamber and the drug supply port are open (5) closed

According to the drug container of the present invention, adjustment of the drug amount required for each individual, which differs depending on the patient's physique and age, is performed by moving some drugs to the drug adjustment room by opening the on-off valve. Therefore, workability can be improved as compared with the conventional case.

The front view which shows the container with a chemical | medical agent which concerns on Embodiment 1 of this invention. The front view which shows the usage example of the container containing a chemical | medical agent of FIG. The front view which shows the usage example of the container containing a chemical | medical agent of FIG. The front view which shows the container with a chemical | medical agent which concerns on Embodiment 2 of this invention. The front view which shows the container with a chemical | medical agent which concerns on Embodiment 3 of this invention. The front view which shows the container with a chemical | medical agent which concerns on Embodiment 4 of this invention. The front view which shows the container with a chemical | medical agent which concerns on Embodiment 5 of this invention. The front view which shows the container containing the chemical | medical agent which concerns on Embodiment 6 of this invention. The front view which shows the container with a chemical | medical agent concerning Embodiment 7 of this invention. The front view which shows the container with a chemical | medical agent which concerns on Embodiment 8 of this invention. The perspective view which shows the chemical | medical agent container which concerns on Embodiment 9 of this invention. The front view of the chemical | medical agent container of FIG. Schematic explaining the operation | movement which melt | dissolves a chemical | medical agent in a solution using the stirring apparatus for the chemical | medical agent container of FIG. The principal part enlarged front view in FIG. The flowchart which shows the operation | movement which melt | dissolves a chemical | medical agent in a solution using the stirring apparatus for the chemical | medical agent container of FIG. The front view which shows the container with a chemical | medical agent which concerns on Embodiment 10 of this invention. (A)-(f) is a figure which shows the use procedure of the container containing a chemical | medical agent of FIG. The flowchart which shows the usage method of the container with a chemical | medical agent of FIG.

Hereinafter, an embodiment of the present invention will be described in detail with reference to the drawings.
(Embodiment 1)
In FIG. 1, a transparent medicine storage chamber 1 has a medicine supply port 2. A transparent medicine adjustment chamber 4 is connected to the medicine storage chamber 1 via a medicine adjustment path 3. A suction port 5 is connected to the medicine adjustment chamber 4. In addition, an on-off valve 6 is provided in the medicine adjustment path 3.

The medicine storage chamber 1 has a cylindrical shape and is flexible. On the other hand, the medicine adjustment chamber 4 is cylindrical and has a fixed shape. The medicine adjustment chamber 4 is provided with an adjustment scale 7.
In the present embodiment, the front and back surfaces of the medicine storage chamber 1 and the medicine adjustment chamber 4 are covered with a transparent cover 8 having flexibility. A medicine supply port 2 is provided outside the cover 8 on the first end side. On the first end side of the cover 8, a hanging hole 9 for adjusting the medicine is provided. In addition, a hanging hole 10 at the time of drug administration is provided on the second end side of the cover 8 opposite to the first end. Further, a suction port 5 is provided on the side portion of the cover 8 so as to face the outside of the cover 8.

In the present embodiment, the medicine manufactured by the pharmaceutical company is in the direction of the medicine supply port 2 facing upward, as shown in FIG. It is stored inside. At this time, the on-off valve 6 is closed as shown in FIG. In addition, after the medicine 11 is supplied into the medicine storage chamber 1, the medicine supply port 2 is also closed. For this reason, the medicine 11 is enclosed in the medicine storage chamber 1, and is delivered to the hospital as a medicine-containing medicine container in this enclosed state.

In the hospital where the drug 11 is delivered, the drug 11 is infused to the patient as follows.
First, as shown in FIG. 2, for example, in a hospital room, a drug-containing drug container with the suspension hole 9 side at the time of drug adjustment facing upward is hung by the hook 12 at the portion of the suspension hole 9 at the time of drug adjustment.

Next, the syringe 13 or the suction device 14 is inserted into the suction port 5.
Thereafter, as shown in FIG. 2, the on-off valve 6 is opened.
Next, the air in the medicine adjustment chamber 4 is aspirated by the syringe 13 or the aspirator 14. Then, the medicine 11 in the medicine storage chamber 1 moves into the medicine adjustment chamber 4 via the medicine adjustment path 3.

Thereby, the amount of the medicine 11 remaining in the medicine storage chamber 1 is set according to the amount of movement of the medicine 11 to the medicine adjustment chamber 4.
That is, the amount of the drug 11 remaining in the drug storage chamber 1 is set so that an appropriate amount of infusion can be performed according to the patient's physique and age.
At this time, if the drug storage chamber 1 is filled with, for example, 1000 cc of the drug 11 and 150 cc is moved into the drug adjustment chamber 4 as described above, the drug storage chamber 1 has 850 cc. The drug 11 is stored.

For example, after preparing 850 cc of medicine 11 in the medicine storage chamber 1, first, the on-off valve 6 is closed, and then the above-described syringe 13 or suction device 14 is pulled out from the suction port 5.
At this time, when the syringe 13 or the suction device 14 is pulled out from the suction port 5, the suction port 5 is automatically closed.

Thereafter, as shown in FIG. 3, the suspension hole 10 at the time of drug administration is suspended from the hook 12 so that the suspension hole 10 side at the time of drug administration faces upward.
Next, the infusion needle 16 is connected to the medicine supply port 2 via the tube 15, and in this state, the infusion needle 16 is inserted into the patient. When the tube 15 is connected to the medicine supply port 2, the medicine supply port 2 is in an open state. Therefore, in this state, if the on-off valve (not shown) interposed in the tube 15 is opened, the medicine 11 in the medicine storage chamber 1 is administered to the patient from the drip needle 16.

As is clear from the above description, in the drug container of the present embodiment, the amount of the drug 11 required for different individuals depending on the patient's physique and age is adjusted by opening the on-off valve 6. This can be done by moving some drugs 11 to the drug adjustment chamber 4. Therefore, workability can be improved as compared with the prior art.
Further, as apparent from the above description, the adjusted medicine 11 is merely moved to the medicine adjustment chamber 4 and is not taken out of the medicine container of the present embodiment. Therefore, also from this point, it is possible to provide a drug container that is easy to handle and has high workability.

For example, when the drug 11 is a cancer drug, it may be necessary to avoid even touching the drug 11 for the safety of the operator.
In the medicine container of this embodiment, the adjusted medicine 11 is simply moved to the medicine adjustment chamber 4 and is not taken out of the medicine container, so that the handling thereof is extremely simple and has high workability. it can.

(Embodiment 2)
FIG. 4 shows the configuration of a medicine container according to Embodiment 2 of the present invention.
A sub-drug storage chamber 18 is connected to the drug storage chamber 1 via a rupture film 17 provided as a first communication portion.
That is, another medicine 19 is stored in the auxiliary medicine storage chamber 18.

In the drug container, immediately before the drip, the rupture film 17 is first broken, and the drug 19 and the drug 11 are mixed.
Next, as described above, in consideration of the patient's physique, age, etc., the amounts of the drugs 11 and 19 in the mixed state are adjusted (partially moved to the drug adjustment chamber 4), and infusion is performed in that state.
(Embodiment 3)
FIG. 5 shows the structure of the medicine container according to Embodiment 3 of the present invention.

In the drug container of this embodiment, a powdered drug 20 is stored in the drug storage chamber 1.
Further, the medicine storage chamber 1 is provided with a rupture film 21 as a first communication portion.
A liquid medicine 23 is stored in the secondary medicine storage chamber 22 connected via the rupture film 21.
Further, the medicine storage chamber 1 is provided with a sub open / close valve 24 as a first communication portion.

A liquid medicine 26 is housed in the secondary medicine storage chamber 25 connected via the secondary opening / closing valve 24.
For this reason, immediately before the drip, first, the rupture film 21 is broken to mix the drug 23 and the drug 20, and the sub-open / close valve 24 is opened to allow the drug 26 to flow into the drug storage chamber 1 and mix. Let

Then, as described above, taking into account the patient's physique and age, etc., the amount of the drug 20, 23, 26 in the mixed state is adjusted (partially moved to the drug adjustment room 4), and in this state, the infusion is performed. Do.
(Embodiment 4)
FIG. 6 shows the configuration of a medicine container according to Embodiment 4 of the present invention.
In the present embodiment, a suction member 27 is connected to the suction port 5.

That is, in the drug containers of Embodiments 1 to 3 described above, it is necessary to connect the syringe 13 or the suction device 14 to the suction port 5, but in this embodiment, the suction member 27 is connected to the suction port 5. By connecting these, the medicine (for example, medicine 11) in medicine storage room 1 can be moved to medicine adjustment room 4 more easily.
(Embodiment 5)
FIG. 7 shows the structure of a medicine container according to Embodiment 5 of the present invention.

In the present embodiment, a secondary drug storage chamber 29 connected to the drug adjustment chamber 4 via a rupture film 28 provided as a second communication portion is provided.
In the present embodiment, the secondary drug storage chamber 29 has a drug as a neutralizing agent that neutralizes the drug 11 stored in the drug storage chamber 1 or a deactivating agent that detoxifies the drug 11 stored in the drug storage chamber 1. 30 is stored.

That is, in the first to fourth embodiments, after the medicine (for example, medicine 11) in the medicine storage chamber 1 is moved to the medicine adjustment chamber 4, no processing is performed.
On the other hand, as in the present embodiment, by providing a secondary drug storage chamber 29 connected to the drug adjustment chamber 4 via a rupture film 28 provided as a second communication portion, the inside of the drug storage chamber 1 is provided. After moving the medicine (for example, medicine 11) to the medicine adjustment chamber 4, it is possible to easily perform a process of mixing the medicine (for example, medicine 11) and the medicine 30 stored in the auxiliary medicine storage chamber 29. it can.

For example, the medicine 30 stored in the auxiliary medicine storage chamber 29 is neutralized with the neutralizing agent that neutralizes the medicine stored in the medicine storage chamber 1 (for example, the medicine 11) or the medicine stored in the medicine storage chamber 1. When a reversible agent or the like is used, a medicine (for example, medicine 11) stored in the medicine storage chamber 1 can be neutralized or detoxified.
In particular, when the drug (for example, drug 11) is a cancer therapeutic drug, it is very toxic, so the drug (for example, drug 11) stored in the drug storage chamber 1 is stored in the drug adjustment chamber 4. It is extremely useful in that it can be neutralized or detoxified after being transferred.

(Embodiment 6)
FIG. 8 shows the configuration of a medicine container according to Embodiment 6 of the present invention.
In the present embodiment, a gas-liquid separation membrane 31 is provided between the drug adjustment chamber 4 and the suction port 5.
In the first to fifth embodiments described above, first, the syringe 13 (see FIG. 2) or the suction device 14 (see FIG. 2) is inserted into the suction port 5.

Thereafter, the on-off valve 6 is opened.
Next, when the air in the drug adjustment chamber 4 is sucked by the syringe 13 or the suction device 14, the drug (for example, the drug 11) in the drug storage chamber 1 passes through the drug adjustment path 3 in the drug adjustment chamber 4. Move to.
Here, when the medicine (for example, medicine 11) in the medicine storage chamber 1 moves into the medicine adjustment room 4 via the medicine adjustment path 3, a small amount of the medicine (for example, medicine 11) depends on the type. There is a risk that the drug will be atomized by negative pressure due to suction. When such a chemical | medical agent is used, there exists a possibility that the atomized trace amount chemical | medical agent may leak outside from the suction opening 5. FIG. As a result, there is a risk of touching a medical worker (for example, a nurse) who performs infusion or the like using this medicine container.

In other words, in the first to fifth embodiments, when the drug (for example, drug 11) is a toxic drug (for example, a drug used for instillation treatment of cancer), the air in the drug adjustment chamber 4 When performing the operation | work which attracts | sucks, there existed a possibility that the atomized trace amount chemical | medical agent might leak out from the suction opening 5 outside. As a result, there is a risk that the medical staff who performs intravenous infusion using this drug container may be violated by the toxicity of the drug.

However, in this embodiment, a gas-liquid separation membrane 31 is provided between the drug adjustment chamber 4 and the suction port 5. For this reason, the atomized trace amount medicine (for example, medicine 11) can be absorbed by gas-liquid separation membrane 31. As a result, it is possible to prevent leakage of the atomized small amount of medicine (for example, medicine 11) to the outside. Therefore, it is possible to prevent the medical staff who performs intravenous infusion using this drug container from being violated by toxicity.

(Embodiment 7)
FIG. 9 shows the configuration of a medicine container according to Embodiment 9 of the present invention.
In the present embodiment, the medicine adjustment chamber 4 is provided with a medicine administration scale 32 for indicating the amount of medicine (for example, medicine 11) stored in the first medicine storage chamber 1.
In other words, in the first to sixth embodiments, as shown in FIGS. 1 to 8, the adjustment scale 7 is described so that the numbers increase sequentially from the opening / closing valve 6 side to the suction port 5 side. Yes.

On the other hand, the medicine container of the present embodiment is described such that the medicine administration scale 32 has a numerical value that decreases sequentially from the opening / closing valve 6 side to the suction port 5 side.
In other words, in the above-described first to sixth embodiments, as described in the first embodiment, the adjustment scale 7 is moved from the medicine storage chamber 1 of the medicine (for example, medicine 11) into the medicine adjustment chamber 4. It shows the amount of movement.

On the other hand, in the present embodiment, the medicine administration scale 32 is a medicine (for example, medicine) stored in the medicine storage chamber 1 after the medicine (for example, medicine 11) is moved from the medicine storage room 1 into the medicine adjustment room 4. 11) is provided to show the quantity.
Below, the specific example which concerns on this embodiment is demonstrated.
For example, in this medicine container, 400 cc medicine (for example, medicine 11) is filled in the medicine storage chamber 1 in advance.

Next, the medicine (for example, medicine 11) is moved from the medicine storage chamber 1 into the medicine adjustment chamber 4 to the position of 250 cc (dotted line A in FIG. 9) of the medicine administration scale 32 in the medicine adjustment chamber 4. As a result, 250 cc of medicine (for example, medicine 11) equivalent to the amount shown in the medicine administration scale 32 of the medicine adjustment room 4 is prepared in the medicine storage room 1 (in the medicine adjustment room 4, actually Is the state where 150cc has been moved.)

As described above, in this embodiment, the amount of the medicine (for example, medicine 11) in the medicine storage room 1 after the movement from the medicine storage room 1 into the medicine adjustment room 4 is determined by the medical worker (for example, nursing) Master) You don't have to do it yourself. That is, the medical staff can more easily adjust the amount of the medicine (for example, the medicine 11) in the medicine storage chamber 1 to the amount required for each patient by directly reading the medicine administration scale 32. Can be adjusted.

Furthermore, since it is not necessary for the medical staff (for example, nurse) to calculate the amount of the medicine (for example, the medicine 11) in the medicine storage chamber 1, the risk of occurrence of a medical accident due to a calculation error or the like as a result. Can be more effectively reduced.
(Embodiment 8)
FIG. 10 shows a configuration of a medicine container according to Embodiment 8 of the present invention.

The present embodiment is different from the configuration of the seventh embodiment in that the inside of the medicine adjustment chamber 4 with the medicine administration scale 32 is evacuated.
That is, in the medicine container of the present embodiment, the inside of the medicine adjustment chamber 4 is in a vacuum state in order to suck a part of the medicine 11 into the medicine adjustment chamber 4.
Accordingly, even if the suction member 27 shown in FIG. 6 or the suction port 5 shown in FIG. 9 is not provided, an appropriate amount of medicine can be easily introduced into the medicine adjustment chamber 4 by operating the on-off valve 6. 11 can be moved.

(Embodiment 9)
First, the structure of the medicine container in the present embodiment will be described.
FIG. 11 is a perspective view showing a medicine container according to the present embodiment. FIG. 12 is a front view showing the medicine container according to the present embodiment.
As shown in FIGS. 11 and 12, the drug container 101 of the present embodiment is connected to a cylindrical drug storage chamber 103 for storing a solution 102 and a drug storage chamber 103 via a cylindrical drug supply path 104. In addition, a flat bag-shaped drug storage chamber 106 storing the drug 105 and a drug supply port 107 connected to the first end side of the cylindrical drug storage chamber 103 are provided.

Here, in this embodiment, the medicine storage chamber 106 has a flat bag shape, and has flexibility to be freely deformed by being pressed from the outside. On the other hand, although the medicine storage chamber 103 is formed in a cylindrical shape having a fixed shape, it may be formed as a cylindrical member having flexibility.
In the present embodiment, the medicine in which the stirrer 108 can be stored in the second end side (the side opposite to the drug supply port 107) opposite to the first end in the cylindrical drug storage chamber 103. The stirring unit 109 is connected.

Here, in this embodiment, the medicine stirring part 109 is transparent and cylindrical, has a regular shape, and the medicine storage chamber 103 side is open.
As shown in FIGS. 11 and 12, the drug container 101 according to the present embodiment is provided with an outer peripheral plane part 110 in the outer peripheral part of the drug storage chamber 103. The outer peripheral plane part 110 is provided with a medicine storage chamber 106.

That is, the outer peripheral flat part 110 is formed by bonding two flat bodies. Accordingly, the above-described cylindrical medicine supply path 104 is formed by covering the medicine storage chamber 106 and not sticking (non-adhering) a part of the two flat bodies.
The drug supply path 104 is provided with a rupture film 113 that separates the drug storage chamber 106 and the drug storage chamber 103.

A holding part 111 and a holding part 112 are provided on the medicine supply port 107 side and the medicine stirring part 109 side in the outer peripheral flat part 110, respectively.
In the present embodiment, the holding part 111 and the holding part 112 are configured by forming a through hole in the outer peripheral plane part 110.
In addition, the stirrer 108 of the drug container 101 of the present embodiment uses a bar magnet sealed with Teflon (registered trademark) or the like. In addition, a long and narrow cylindrical shape is used.

Next, a method for using the drug container 101 of the present embodiment will be described.
In the present embodiment, the solution 102 and the drug 105 manufactured by the pharmaceutical company are sealed in the drug storage chamber 103 and the drug 105 in the drug storage chamber 106 in the drug company or the drug enclosure factory, respectively ( It is cut off from outside air).
Then, the drug container 101 is delivered to the hospital in a state where the dissolution liquid 102 and the drug 105 are sealed.

In a hospital where the drug container 101 is delivered, first, when a medical worker (for example, a nurse) breaks the rupture film 113 immediately before instilling a patient, the drug 105 in the drug storage chamber 106 is removed. The medicine 105 is supplied to the medicine storage chamber 103 through the medicine supply path 104, and the medicine 105 is dissolved in the solution 102 in the medicine storage chamber 103. In other words, the rupture film 113 has a sufficiently thin film shape by the two planar bodies constituting the outer peripheral plane part 110, so that by applying a force from the outside to this part, a state of being easily separated can be obtained. It can be canceled.

Thereafter, the medical staff can administer the drug in which the solution 102 and the drug 105 are dissolved as an infusion to the patient.
Here, in the medicine container 101 of the present embodiment, the details of the work for dissolving the dissolving liquid 102 and the medicine 105 stored in the medicine container 101 will be described.
FIG. 13 is a schematic diagram for explaining the operation of dissolving the drug in the solution using the stirring device. FIG. 14 is an enlarged front view of a main part in FIG.

In the present embodiment, as described above, with the drug 105 in the drug storage chamber 106 being supplied to the drug storage chamber 103 via the drug supply path 104, the drug agitating unit 109 is on the lower side, The medicine container 101 is set in the stirring device 114 shown in FIG.
Thereafter, the stirrer 108 housed in the drug stirring unit 9 in the drug container 101 is rotated by the stirring device 114 to dissolve the solution 102 and the drug 105.

As shown in FIGS. 13 and 14, the stirring device 114 in the present embodiment incorporates a drive unit 115.
A housing 117 having a recess 116 for placing the medicine stirring part 109 of the medicine container 101 is provided on the driving part 115. A turbidity measuring unit 118 for measuring the turbidity of the drug stirring unit 109 of the drug container 101 is provided on the top of the casing 117.

In addition, the stirring device 114 includes a notification unit 119 for notifying the outside of the operation (for example, a medical worker, etc.) of the operation completion when the operation of dissolving the drug 105 and the solution 102 is completed, and the driving unit 115 and turbidity measurement. The control unit 120 is connected to the notification unit 119 and controls the operation of the driving unit 115 and the notification unit 119.
In the present embodiment, the drive unit 115 has a mechanism for rotating a magnet connected to a motor. Therefore, when the motor of the drive unit 115 rotates, the stirrer 108 in the medicine container 101 can also be rotated so as to follow it.

In the present embodiment, the drug stirring unit 109 in which the stirring bar 108 in the drug container 101 is arranged is formed to be cylindrical (configured with a cylindrical container). Thereby, the stirring bar 108 can be rotated more smoothly in the drug stirring unit 109.
Moreover, in this embodiment, the chemical | medical agent stirring part 109 of the chemical | medical agent container 101 is formed with the transparent material (it is comprised with the transparent container). Thereby, the turbidity measuring unit 118 of the stirring device 114 can measure the turbidity of the solution 102 inside the drug stirring unit 109, that is, the degree of dissolution of the solution 102 and the drug 105.

Here, a method for automatically dissolving the drug 105 in the solution 102 using the stirring device 114 will be described with respect to the drug container 101 storing the solution 102 and the drug 105 in the present embodiment.
FIG. 15 is a flowchart showing an operation of dissolving the drug in the solution using the stirring device 114 in the drug container storing the solution and the drug according to the present embodiment.

First, the drug stirring unit 109 of the drug container 101 is set in the recess 116 of the casing 117 of the stirring device 114 (S1 in FIG. 15). At this time, the suspension arm 122 is passed through the holding portion 112 to be held from above.
Next, the type and amount of the solution 102 and the drug 105 stored in the drug container 101 are input to the control unit 120 of the stirring device 114 (S2 in FIG. 15).

In this embodiment, a barcode on which information including the type and amount of the dissolved solution 102 and the medicine 105 stored in advance is read by a barcode reader (not shown) mounted on the stirring device 114. Then, the information read by the barcode reader is input to the control unit 120, whereby the types and amounts of the solution 102 and the drug 105 are input.

Next, based on the inputted type and amount of the solution 102 and the medicine 105, the first rotation speed N1 for rotating the stirrer 108 and the first rotation time (T1) for rotating the stirrer 108 are determined. To do.
Next, the rotation operation of the drive unit 115 is started, and control is performed so that the rotation speed of the stirrer 108 becomes the first rotation speed (N1) (S3 in FIG. 15, first stirring operation).

In the present embodiment, the dissolution experiment of the dissolution liquid 102 and the drug 105 is performed in advance, and the rotation speed and rotation speed of the stirrer 108 for sufficiently dissolving the drug 105 in the dissolution liquid 102 are obtained. That is, the rotation speed and rotation time obtained in the dissolution experiment are respectively set as a first rotation speed N1 and a first rotation time (T1) in a memory (not shown) inside the control unit 120 of the stirring device 114. Stored in advance.

Therefore, based on the type / amount of the solution 102 and the drug 105 read by the barcode reader, the first rotation speed N1 for rotating the stirrer 108 and the first rotation time (T1) for rotating the stirrer 108 ) And are set.
Next, the time (T) from the start of the first stirring operation is measured, and the time (T) from the start of the first stirring operation is determined as the first rotation time ( It is determined whether or not T1) has elapsed (T> T1) (S4 in FIG. 15).

If T> T1, the process proceeds to the next step. On the other hand, if T <T1, the first stirring operation in S3 in FIG. 15 is continued.
In the present embodiment, the control unit 120 of the stirring device 114 measures and determines the time (T) from the start of the first stirring operation.
When T> T1, the rotational speed of the stirrer 108 is decreased (S5 in FIG. 15).

In the present embodiment, in S5, the rotation speed is half of the first rotation speed N1 (0.5 × N1). In this embodiment, this operation is performed by the control unit 120 of the stirring device 114.
Here, the reason why the rotational speed of the stirrer 108 is decreased is that the vortex 121 (see FIG. 14) in the drug stirring unit 109 is reduced, and this vortex 121 affects the turbidity measurement in the next step. This is to prevent it from occurring.

Next, in order to confirm that the drug 105 is completely dissolved in the solution 102, the turbidity measuring unit 118 of the stirring device 114 measures the turbidity of the solution 102 inside the drug stirring unit 109 (FIG. S6 in 15).
Next, it is determined whether or not the turbidity of the solution 102 inside the drug stirring unit 109 is equal to or higher than a desired turbidity (S7 in FIG. 15). In the present embodiment, this determination is made by the control unit 120 of the stirring device 114.

In this embodiment, a dissolution experiment of the dissolution liquid 102 and the drug 105 is performed in advance, the turbidity when the drug 105 is completely dissolved in the dissolution liquid 102 is measured, and the turbidity is controlled by the stirring device 114. The desired turbidity is stored in a memory (not shown) inside the unit 120. Thereby, the stored desired turbidity and the actually measured turbidity are compared to determine whether or not the desired turbidity is equal to or higher than the desired turbidity.

Here, when the turbidity of the solution 102 inside the medicine stirring unit 109 is equal to or higher than the desired turbidity, the rotation of the stirrer 108 is stopped (S8 in FIG. 15).
Thereafter, the notifying unit 119 of the stirrer 114 notifies the outside of the stirrer 114 that the dissolution of the dissolving liquid 102 and the drug 105 has been completed (S9 in FIG. 15). In the present embodiment, a form in which an indicator lamp is turned on is used as the notification unit 119.

On the other hand, when the turbidity of the solution 102 in the drug stirring unit 109 is equal to or lower than the desired turbidity, the second rotation speed N2 for rotating the stirrer 108 and the second rotation for rotating the stirrer 108 are performed. The time (T2) is determined, and the rotational operation of the drive unit 115 is started, and control is performed so that the rotational speed of the stirrer 108 becomes the second rotational speed (N2) (S10 in FIG. 2 stirring operation).

In the present embodiment, the second rotation speed N2 is set to the same rotation speed as the first rotation speed N1, and the second rotation time (T2) is set to 5 minutes. Yes.
Next, the time (Ta) from the start of the second stirring operation is measured, and the time (Ta) from the start of the second stirring operation is inputted as the second rotation time (T2). Is determined (Ta> T2) (S11 in FIG. 15).

Here, when Ta> T2, the process proceeds to S5 in FIG. 15 (reducing the rotational speed of the stirrer 108), and then the turbidity of the solution 102 inside the drug stirring unit 109 is measured. If Ta <T2, the second stirring operation is continued (see S11). That is, the second stirring operation is continued until the turbidity of the solution 102 inside the drug stirring unit 109 becomes equal to or higher than the desired turbidity.

In the present embodiment, a drug is used that becomes cloudy when the drug 105 is dissolved in the solution 102. However, when a drug that increases transparency when the drug 105 is dissolved in the solution 102 is used. The turbidity measuring unit 118 may measure the transparency.
As described above, according to the present embodiment, the drug 105 in the drug storage chamber 106 is supplied to the solution 102 in the drug storage chamber 103 via the drug supply path 104 and then provided in the drug stirring unit 109. The drug 105 can be automatically dissolved in the dissolving liquid 102 by rotating the stirring bar 108. As a result, it is possible to provide a drug container with higher workability than before.

In particular, when the drug 105 is, for example, a drug used for instillation treatment of cancer, it is very toxic and there is a risk that the medical staff himself may be violated by toxicity during work.
In this embodiment, the solution 102 is stored in the drug storage chamber 103 and the drug 105 is stored in the drug storage chamber 106 in a state of being shielded from the outside air, and only the rupture film 113 is broken during mixing. Both can be mixed. Therefore, it is possible to prevent the medical staff from being violated by the toxicity of the medicine.

Then, after the drug 105 is automatically dissolved in the dissolution liquid 102, the hanging arm (not shown) utilized during the drip is passed through the holding unit 111 and held in a state where the drug container 101 is inverted. The Next, an infusion needle (not shown) is connected to the medicine supply port 107, and then the patient is infused.
(Embodiment 10)
FIG. 16 is a front view of the medicine container according to the present embodiment.

As shown in FIG. 16, the medicine storage chambers 201, 202, and 203 are connected to the medicine supply paths 204, 204, and 204, respectively.
Further, a single medicine supply port 205 is provided on the opposite side of each medicine supply path 204, 204, 204 from the medicine storage chambers 201, 202, 203.
Further, an opening / closing valve 206 is provided at a portion of the medicine supply path 204 to which the medicine storage chambers 201, 202, and 203 are connected.

In the present embodiment, the on-off valve 206 has a handle 207 that switches the open / close state of the on-off valve 206.
The handle 207 can be rotated only in one counterclockwise direction within a range from a dotted line (1) to a dotted line (5) in FIG. The handle 207 can be fixed at each position of the dotted line (1), the dotted line (2), the dotted line (3), the dotted line (4), and the dotted line (5).

Here, when the handle 207 of the on-off valve 206 is located at each position from the dotted line (1) to the dotted line (5) in FIG.
-Position of dotted line (1): state not connected to any of medicine storage chambers 201, 202, 203 (closed state)
The position of the dotted line (2): the medicine storage chamber 201 and the medicine supply port 205 are open. The position of the dotted line (3): The medicine storage chamber 202 and the medicine supply port 205 are open. The position of the dotted line (4): The medicine storage chamber 203 and the medicine supply port 205 are in an open state / dotted line (5) position: not connected to any of the medicine storage chambers 201, 202, 203 (closed state)
In other words, in the present embodiment, by operating the handle 207 of the on-off valve 206, the open / close state of the medicine storage chambers 201, 202, 203 and the medicine supply port 205 is changed as follows (1) to (5). It can be switched sequentially.
(1) Closed state (S101 in FIG. 18)
(2) First drug storage chamber (that is, drug storage chamber 201) and drug supply port 205 are open (S102 in FIG. 18).
(3) The second medicine storage chamber (that is, the medicine storage chamber 202) and the medicine supply port 205 are open (S103 in FIG. 18).
(4) The third medicine storage chamber (that is, the medicine storage chamber 203) and the medicine supply port 205 are open (S104 in FIG. 18).
(5) Closed state (S105 in FIG. 18)
In the present embodiment, the medicine storage chambers 201, 202, and 203 are made of flexible cylindrical members. In the present embodiment, the medicine storage chambers 201, 202, and 203 are each covered with a flexible and transparent cover 208 on the front and back surfaces. A drug supply port 205 is provided on the outer side of the cover 208 on the first end side, and a hanging hole 209 for adjusting the drug is provided on the first end side of the cover 208. In addition, a suspension hole 210 for drug administration is provided on the second end side of the cover 208 opposite to the first end.

Next, the usage method of the chemical | medical agent container of this embodiment is demonstrated.
In the present embodiment, the medicine container is oriented so that the medicine supply port 205 (that is, the hanging hole 209 at the time of medicine adjustment) comes to the top, and the medicine manufactured by the pharmaceutical company is used in the pharmaceutical company or the medicine enclosure factory. From the medicine supply port 205, the medicine is stored in the medicine storage chambers 201, 202, 203.

In the present embodiment, the drugs stored in the drug storage chambers 201, 202, and 203 are referred to as drugs 211, 212, and 213, respectively.
After the drugs 211, 212, and 213 are supplied into the drug storage chambers 201, 202, and 203, respectively, the drug supply port 205 is closed. Therefore, the medicines 211, 212, and 213 are sealed in the medicine storage chambers 201, 202, and 203, respectively.

The drug container is delivered to the hospital as a drug-containing drug container in this sealed state. In this sealed state, the handle 7 of the opening / closing valve 206 of the medicine container containing the medicine is not connected to any of the above-described dotted line (1) (the medicine storage chambers 201, 202, 203 are in the closed state). (See FIG. 17A)).
Next, in the hospital which has received the delivery, the medicine 219 and the medicine 212 are mixed in the medicine storage chamber 202 (see FIG. 17B).

Next, the dosage of the medicine mixed in the medicine storage chamber 202 is adjusted using the suction member (see FIG. 17C).
Next, the patient is infused as follows.
As shown in FIG. 16, the drug container is suspended by inserting a hook (not shown) into the suspension hole 210 at the time of drug administration so that the suspension hole 210 side at the time of drug administration is at the top.

Next, an infusion needle (not shown) is connected to the medicine supply port 205 via a tube (not shown), and in this state, the infusion needle is inserted into the patient.
Thereafter, the handle 207 of the on-off valve 206 is rotated counterclockwise to the position indicated by the dotted line (2) (the medicine storage chamber 201 and the medicine supply port 205 are in the open state). In this state, the medicine 211 stored in the medicine storage chamber 201 is administered to the patient from the drip needle (see FIG. 17D).

Next, when the administration of the medicine 211 is completed, the handle 207 of the on-off valve 206 is rotated counterclockwise to the position of the dotted line (3) described above (the medicine storage chamber 202 and the medicine supply port 205 are in the open state). Let In this state, the medicine 212 stored in the medicine storage chamber 202 is administered to the patient from the drip needle (see FIG. 17 (e)).
Further, when the administration of the medicine 212 is completed, the handle 7 of the on-off valve 206 is rotated counterclockwise so as to be located at the position indicated by the dotted line (4) (the medicine storage chamber 203 and the medicine supply port 205 are open). . In this state, the medicine 213 stored in the medicine storage chamber 203 is administered to the patient from the drip needle (see FIG. 17 (f)).

Next, when the administration of the medicine 212 is completed, that is, when the administration of all the medicines stored in the medicine container containing the medicine (the medicines 211, 212, and 213 in this embodiment) is completed, the handle 207 of the on-off valve 206 is turned over. After rotating clockwise, the drip needle is removed from the patient after being positioned at the position of the dotted line (5) described above (not connected to any of the medicine storage chambers 201, 202, 203 (closed state)). .

As is apparent from the above description, in the present embodiment, it is not necessary to perform a plurality of tube connections at the time of preparation for infusion treatment, which is one of the causes that the medicine is exposed to the outside. For this reason, there is no exposure of the medicine at the time of preparation for the drip treatment, and as a result, it is possible to further improve the safety for the medical staff handling these.
For example, if the drug 211 is a physiological saline, the drug 212 is an anticancer drug, the drug 213 is a physiological saline, and the drug container is used for infusion of cancer treatment, exposure of the anticancer drug must be avoided. There are also things.

However, in this embodiment, the switching operation of the administration medicine can be performed only by the switching operation of the on-off valve 206 inside the medicine container. Thereby, handling is very simple and the safety | security to a medical worker can further be improved.
In addition, in this embodiment, although an example of the chemical | medical agent container which can administer three types of chemical | medical agents 211,212,213 to a patient was disclosed, this invention is not limited to this.

For example, in a medicine container provided with N medicine storage chambers for storing N kinds of medicines, a medicine supply path provided in the N medicine storage rooms, and an on-off valve connected to the medicine supply path. On the other hand, the present invention may be applied.
In this case, the on-off valve can switch the open / close state between the respective drug storage chambers 201, 202, 203 and the drug supply port in the order of (1) to (5) below. Thereby, a medicine container which can administer many kinds of medicines to a patient can be provided.
(1) Closed state (2) First drug storage chamber and drug supply port open state (3) Second drug storage chamber and drug supply port open state (4) N (where N is 2 (Natural number) The medicine storage chamber and the medicine supply port are in the open state (5) in the closed state. Further, in the present embodiment, an example of the medicine container in which three kinds of medicines are switched in five stages by the opening / closing valve 206 is disclosed. However, the present invention is not limited to this.

For example, when the medicine 211 is a physiological saline, the medicine 212 is an anticancer agent, the medicine 213 is a physiological saline, and the physiological saline communicates with the medicine supply port 205, a medical worker can perform a connection operation. Harmless even if exposed to saline. Therefore, the first and last order in which the on-off valve 205 is closed is omitted, and the three open / close states of each medicine storage chamber and medicine supply port are switched in the order of (1) to (3) below. It can also be simplified in order.
(1) First drug storage chamber (ie, drug storage chamber 201) and drug supply port 205 are open (2) Second drug storage chamber (ie, drug storage chamber 202) and drug supply port 205 are open (3 ) The third medicine storage chamber (that is, the medicine storage chamber 203) and the medicine supply port 205 are open. In this embodiment, the handle 7 of the on-off valve 206 is rotated only in a certain direction (in this embodiment, Counterclockwise).

As a result, it is possible to prevent a medical worker handling the medicine container from rotating the handle 207 of the on-off valve 206 by mistake. As a result, the occurrence of a medical accident can be prevented more reliably.
In the configurations of the first to third embodiments and the fifth to eighth embodiments, the negative pressure can be maintained in the medicine adjustment chamber by continuing the suction for some time after the on-off valve is closed. For this reason, there is a safety merit that the medicine is difficult to leak out during storage of the container after medication or at the time of disposal.

In the present invention, it is possible to adjust the amount of drug required for each individual different depending on the patient's physique, age, etc., by opening the on-off valve and moving some drugs to the drug adjustment room, Since it has an effect that workability can be improved as compared with the conventional case, it is expected to be widely used as a medicine container and a medicine container containing a medicine.

DESCRIPTION OF SYMBOLS 1 Drug storage chamber 2 Drug supply port 3 Drug adjustment path 4 Drug adjustment chamber 5 Suction port 6 On-off valve 7 Adjustment scale 8 Cover 9 Hanging hole at the time of drug adjustment 10 Hanging hole at the time of drug administration 11 Drug 12 Hook 13 Syringe 14 Suction device 15 Tube 16 Infusion Needle 17 Breaking Film 18 Secondary Drug Storage Chamber 19 Drug 20 Drug 21 Breaking Film 22 Secondary Drug Storage Chamber 23 Drug 24 Secondary Opening Valve 25 Secondary Drug Storage Chamber 26 Drug 27 Suction Member 28 Breaking Film 29 Secondary Drug Storage Chamber 30 Drug 31 Gas-liquid separation membrane 32 Drug administration scale 33 Check valve 101 Drug container 102 Dissolved solution 103 Drug storage chamber 104 Drug supply path 105 Drug 106 Drug storage chamber 107 Drug supply port 108 Stirrer 109 Drug stirring section 110 Outer peripheral plane section 111 112 Holding part 113 Breaking film 11 Stirrer 115 Drive unit 116 Recess 117 Housing 118 Turbidity measurement unit 119 Notification unit 120 Control unit 121 Vortex 122 Hanging arms 201, 202, 203 Drug storage chamber 204 Drug supply path 205 Drug supply port 206 Opening / closing valve 207 Handle 208 Cover 209 Hanging hole 210 during drug adjustment Hanging hole 211, 212, 213 during drug administration

Claims (27)

1. A medicine storage chamber having a medicine supply port;
   While adjusting the drug stored in the drug storage chamber, a drug adjustment chamber having a fixed form,
   A drug adjustment path connecting the drug storage chamber and the drug adjustment chamber;
   A suction port connected to the drug adjustment chamber;
   An on-off valve provided in the medicine adjustment path;
   Drug container with.
2. A suction member is connected to the suction port.
   The drug container according to claim 1.
3. The medicine storage room has flexibility,
   The medicine container according to claim 1 or 2.
4. The medicine adjustment room has an adjustment scale for measuring the amount of the medicine,
   The drug container according to claim 3.
5. A flexible cover that covers the medicine storage chamber and the medicine adjustment chamber;
   A medicine supply port provided outside one end of the cover;
   A hanging hole for adjusting the medicine provided on one end side of the cover,
   A hanging hole for drug administration provided on the other end side of the cover,
   Further equipped with,
   The medicine container according to any one of claims 1 to 4.
6. The suction port is provided outside the cover,
   The drug container according to claim 5.
7. An auxiliary medicine storage room,
   A first communication portion for communicating the medicine storage chamber and the auxiliary medicine storage chamber;
   Further equipped with,
   The medicine container according to any one of claims 1 to 6.
8. The drug container according to claim 7, wherein the first communication part includes a rupture film provided between the drug storage chamber and the sub-drug storage chamber.
9. The drug container according to claim 7, wherein the first communication part includes a sub open / close valve provided between the drug adjustment chamber and the sub drug storage chamber.
10. An auxiliary medicine storage room,
    A second communication portion for communicating the medicine storage chamber and the auxiliary medicine storage chamber;
    Further equipped with,
    The drug container according to claim 1.
11. The second communication portion includes a rupture film provided between the drug adjustment chamber and the auxiliary drug storage chamber.
    The drug container according to claim 10.
12. The drug stored in the auxiliary drug storage chamber is a neutralizing agent that neutralizes the drug stored in the drug storage chamber, or a deactivating agent that detoxifies the drug stored in the drug storage chamber.
    The medicine container according to claim 10 or 11.
13. A gas-liquid separation membrane provided between the drug adjustment chamber and the suction port,
    The drug container according to claim 1.
14. The drug adjustment chamber has a drug administration scale provided to indicate the amount of drug stored in the drug storage chamber.
    The drug container according to claim 1.
15. A drug container according to any one of claims 1 to 14,
    A drug stored in the drug storage chamber of the drug container;
    A container with a medicine.
16. The medicament includes a cancer therapeutic agent,
    The medicine container according to claim 15.
17. A drug adjustment chamber containing a solution,
    A drug storage chamber that is connected to the drug adjustment chamber via a drug supply path and stores a drug,
    A drug administration port connected to the drug adjustment chamber;
    A drug stirring unit that is connected to the drug adjusting chamber and can store a stirring bar therein,
    Drug container with.
18. The drug stirring unit is a container opened on the drug adjustment chamber side.
    The drug container according to claim 17.
19. The drug stirring unit is a cylindrical container.
    The drug container according to claim 18.
20. The container is transparent;
    The medicine container according to claim 18 or 19.
21. The drug stirring unit is provided on the side opposite to the drug administration port of the drug adjustment chamber,
    The drug container according to any one of claims 17 to 20.
22. An outer peripheral flat surface provided in an outer peripheral portion of the medicine adjustment chamber;
    A holding part provided on the drug administration port side and the drug stirring part side in the outer peripheral plane part,
    Further equipped with,
    The drug container according to claim 21.
23. The holding portion is a through hole provided in the outer peripheral plane portion.
    The drug container according to claim 22.
24. The medicine storage chamber is provided in the outer peripheral plane portion.
    24. A drug container according to claim 22 or 23.
25. The drug stored in the drug storage room is a cancer drug.
    The medicine container according to any one of claims 17 to 24.
26. A plurality of medicine storage chambers, a plurality of medicine supply passages connected to each of the plurality of medicine storage chambers, and a medicine supply port connected to the plurality of medicine supply passages via an on-off valve. A method of using a drug container,
    The on-off valve is a method of using a medicine container that switches between opening and closing states of the medicine storage chamber and the medicine supply port in the order of (1) to (5) below.
    (1) Closed state (2) First drug storage chamber and drug supply port open state (3) Second drug storage chamber and drug supply port open state (4) N (where N is 2 (Natural number) The drug storage chamber and the drug supply port are open (5) closed
27. The on-off valve switches the on-off state by rotating only in a certain direction.
    27. A method of using the drug container according to claim 26.

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