WO2013042140A3 - Non antibiotic,non peptide compounds for antibiotic efficacy & safety enhancement - Google Patents

Non antibiotic,non peptide compounds for antibiotic efficacy & safety enhancement Download PDF

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Publication number
WO2013042140A3
WO2013042140A3 PCT/IN2012/000634 IN2012000634W WO2013042140A3 WO 2013042140 A3 WO2013042140 A3 WO 2013042140A3 IN 2012000634 W IN2012000634 W IN 2012000634W WO 2013042140 A3 WO2013042140 A3 WO 2013042140A3
Authority
WO
WIPO (PCT)
Prior art keywords
antibiotic
peptide compounds
efficacy
resistance
safety enhancement
Prior art date
Application number
PCT/IN2012/000634
Other languages
French (fr)
Other versions
WO2013042140A2 (en
WO2013042140A4 (en
Inventor
Manu Chaudhary
Original Assignee
Manu Chaudhary
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Manu Chaudhary filed Critical Manu Chaudhary
Publication of WO2013042140A2 publication Critical patent/WO2013042140A2/en
Publication of WO2013042140A3 publication Critical patent/WO2013042140A3/en
Publication of WO2013042140A4 publication Critical patent/WO2013042140A4/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/22—Boron compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

The present invention provides one or more non antibiotic non peptidic entity to augment antimicrobial activity of one or more antimicrobial agent for combating microbial resistance The non antibiotic non peptidic entity is used individually or in combination with one or more antibiotic as single unit dose or is presented through a suitable medium The non antibiotic non peptidic entity make one or more accompanying antibiotic effective by rendering eradication of antimicrobial resistance broadening spectrum and reducing multi bacterial resistance
PCT/IN2012/000634 2011-09-23 2012-09-24 Non antibiotic,non peptide compounds for antibiotic efficacy & safety enhancement WO2013042140A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN2792/DEL/2011 2011-09-23
IN2792DE2011 2011-09-23

Publications (3)

Publication Number Publication Date
WO2013042140A2 WO2013042140A2 (en) 2013-03-28
WO2013042140A3 true WO2013042140A3 (en) 2013-05-23
WO2013042140A4 WO2013042140A4 (en) 2013-07-25

Family

ID=47178258

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2012/000634 WO2013042140A2 (en) 2011-09-23 2012-09-24 Non antibiotic,non peptide compounds for antibiotic efficacy & safety enhancement

Country Status (1)

Country Link
WO (1) WO2013042140A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105543198B (en) * 2016-01-21 2018-05-04 河南新仰韶生物科技有限公司 Application of the sodium salicylate during fermentation prepares Pullulanase
GB201616909D0 (en) * 2016-10-05 2016-11-16 Helperby Therapeutics Ltd Combination
CN112236163A (en) * 2018-06-13 2021-01-15 京都生物制药株式会社 Enhancement of depsipeptide antibiotic antibacterial action using synergistic amounts of boric acid
CA3134413A1 (en) * 2019-03-20 2020-09-24 Alphyn Biologics, Llc Topical croton lechleri compositions for the treatment of acute bacterial skin or skin structure infection
CN111956642A (en) * 2020-09-17 2020-11-20 福建师范大学 Method for improving sterilization efficiency of aminoglycoside antibiotics by indole and derivatives thereof

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1283050A2 (en) * 1995-01-13 2003-02-12 XOMA Technology Ltd. Improved therapeutic compositions comprising bactericidal/permeability-increasing (BPI) protein products
US20060084639A1 (en) * 2004-10-14 2006-04-20 Wyeth Compositions containing piperacillin and tazobactam useful for injection
WO2006059344A1 (en) * 2004-12-02 2006-06-08 Venus Remedies Limited Compositions for combating beta-lactamase-mediated antibiotic resistance using beta-lactamase inhibitors useful for injection
EP2062581A1 (en) * 2006-08-25 2009-05-27 Tianjin Hemey Bio-Tech Co., Ltd. The antibiotics composition comprising beta-lactam antibiotics and ionic chelating agents
WO2009066117A1 (en) * 2007-11-22 2009-05-28 Pharmateka Kiskereskedelmi Bt Use of edta and its derivatives for prevention and treatment of bacterial intestinal diseases of pigs and for increasing the effects of antibiotics exerted in such diseases
WO2009070638A1 (en) * 2007-11-30 2009-06-04 Toltec Pharmaceuticals, Llc Compositions and methods for treating vaginal infections and pathogenic vaginal biofilms
WO2010013640A1 (en) * 2008-07-28 2010-02-04 Yamaguchi Keizo Potentiator of therapeutic efficacy on infectious disease
WO2011091322A2 (en) * 2010-01-22 2011-07-28 Hyprotek, Inc. Antimicrobial agents and methods of use
WO2012064865A1 (en) * 2010-11-09 2012-05-18 The University Of Chicago Role of adam10 and its relevance to disease and therapeutics

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1283050A2 (en) * 1995-01-13 2003-02-12 XOMA Technology Ltd. Improved therapeutic compositions comprising bactericidal/permeability-increasing (BPI) protein products
US20060084639A1 (en) * 2004-10-14 2006-04-20 Wyeth Compositions containing piperacillin and tazobactam useful for injection
WO2006059344A1 (en) * 2004-12-02 2006-06-08 Venus Remedies Limited Compositions for combating beta-lactamase-mediated antibiotic resistance using beta-lactamase inhibitors useful for injection
EP2062581A1 (en) * 2006-08-25 2009-05-27 Tianjin Hemey Bio-Tech Co., Ltd. The antibiotics composition comprising beta-lactam antibiotics and ionic chelating agents
WO2009066117A1 (en) * 2007-11-22 2009-05-28 Pharmateka Kiskereskedelmi Bt Use of edta and its derivatives for prevention and treatment of bacterial intestinal diseases of pigs and for increasing the effects of antibiotics exerted in such diseases
WO2009070638A1 (en) * 2007-11-30 2009-06-04 Toltec Pharmaceuticals, Llc Compositions and methods for treating vaginal infections and pathogenic vaginal biofilms
WO2010013640A1 (en) * 2008-07-28 2010-02-04 Yamaguchi Keizo Potentiator of therapeutic efficacy on infectious disease
WO2011091322A2 (en) * 2010-01-22 2011-07-28 Hyprotek, Inc. Antimicrobial agents and methods of use
WO2012064865A1 (en) * 2010-11-09 2012-05-18 The University Of Chicago Role of adam10 and its relevance to disease and therapeutics

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
BUSH K ET AL: "New [beta]-lactam antibiotics and [beta]-lactamase inhibitors", EXPERT OPINION ON THERAPEUTIC PATENTS 2010 INFORMA HEALTHCARE GBR, vol. 20, no. 10, October 2010 (2010-10-01), pages 1277 - 1293, XP007921464, ISSN: 1354-3776 *
DATABASE WPI Week 201014, 2010 Derwent World Patents Index; AN 2010-B37099, XP002690860 *
FARCA A M ET AL: "POTENTIATION OF ANTIBIOTIC ACTIVITY BY EDTA-TROMETHAMINE AGAINST THREE CLINICALLY ISOLATED GRAM-POSITIVE RESISTANT BACTERIA. AN IN VITRO INVESTIGATION", VETERINARY RESEARCH COMMUNICATIONS, AMSTERDAM, NL, vol. 18, no. 1, 1 January 1994 (1994-01-01), pages 1 - 06, XP009068138, ISSN: 0165-7380, DOI: 10.1007/BF01839255 *
HEMAISWARYA S ET AL: "Synergism between natural products and antibiotics against infectious diseases", PHYTOMEDICINE, GUSTAV FISCHER VERLAG, STUTTGART, DE, vol. 15, no. 8, 1 August 2008 (2008-08-01), pages 639 - 652, XP022819250, ISSN: 0944-7113, [retrieved on 20080703], DOI: 10.1016/J.PHYMED.2008.06.008 *

Also Published As

Publication number Publication date
WO2013042140A2 (en) 2013-03-28
WO2013042140A4 (en) 2013-07-25

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