WO2013016741A1 - Complément alimentaire utilisable dans le cadre d'un programme d'amaigrissement - Google Patents
Complément alimentaire utilisable dans le cadre d'un programme d'amaigrissement Download PDFInfo
- Publication number
- WO2013016741A1 WO2013016741A1 PCT/ZA2011/000053 ZA2011000053W WO2013016741A1 WO 2013016741 A1 WO2013016741 A1 WO 2013016741A1 ZA 2011000053 W ZA2011000053 W ZA 2011000053W WO 2013016741 A1 WO2013016741 A1 WO 2013016741A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- insulin
- dietary supplement
- berberine
- weight loss
- fat
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/30—Dietetic or nutritional methods, e.g. for losing weight
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
Definitions
- Insulin is an important controller of organic metabolism. It acts both directly and indirectly on most bodily tissues. Its actions can be divided into two broad categories:
- the invention is based on the proposition that aspects of fat breakdown and use for providing energy are enhanced in the absence of insulin. This can occur normally between meals when secretion of insulin is minimal but the effect becomes extreme in diabetes mellitus when secretion of insulin is almost absent. When this happens, the aforementioned effects of insulin causing the production and storage of fat are reversed.
- a dominant effect is that the enzyme hormone-sensitive lipase in the fat cells become strongly activated. This causes hydrolysis of stored triglycerides, releasing large quantities of fatty acids and glycerol from the adipose tissue into the circulating blood. The net effect or result is significant weight-loss.
- a goal in this respect is a strategy in which the insulin level is lowered to a value which is still healthy but which does not promote fat deposition and fat storage, thereby counteracting insulin's obesity promoting effects.
- the invention consists of a combination of naturally derived compounds and plant extracts that display complementary and synergistic pharmaceutical effects, all of which have been proven to be useful for the treatment or alleviation of insulin resistance.
- the mode of action is via a triple-action mechanism, which optimises catabolic metabolism by lowering insulin levels and increasing the usage of fat for energy purposes, thereby assisting with weight loss.
- the invention provides a dietary supplement which includes, in combination, berberine, banaba leaf and inositol.
- LDLR low-density lipoprotein receptors
- InsR insulin receptors
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Nutrition Science (AREA)
- Epidemiology (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Botany (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Obesity (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
La présente invention concerne un complément alimentaire utilisable dans le cadre d'un programme d'amaigrissement, ledit complément alimentaire contenant de la berbérine, des feuilles de banaba et de l'inositol.
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/ZA2011/000053 WO2013016741A1 (fr) | 2011-07-22 | 2011-07-22 | Complément alimentaire utilisable dans le cadre d'un programme d'amaigrissement |
ZA2014/01237A ZA201401237B (en) | 2011-07-22 | 2014-02-19 | Dietary supplement for use in a weight loss program |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/ZA2011/000053 WO2013016741A1 (fr) | 2011-07-22 | 2011-07-22 | Complément alimentaire utilisable dans le cadre d'un programme d'amaigrissement |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2013016741A1 true WO2013016741A1 (fr) | 2013-01-31 |
Family
ID=44543898
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/ZA2011/000053 WO2013016741A1 (fr) | 2011-07-22 | 2011-07-22 | Complément alimentaire utilisable dans le cadre d'un programme d'amaigrissement |
Country Status (2)
Country | Link |
---|---|
WO (1) | WO2013016741A1 (fr) |
ZA (1) | ZA201401237B (fr) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2923701A1 (fr) | 2014-03-27 | 2015-09-30 | Neopharmed Gentili S.r.l. | Formulation pour le traitement et le contrôle du syndrome métabolique et des troubles corrélés |
ITUA20163025A1 (it) * | 2016-04-29 | 2017-10-29 | Sochim Int S P A | Composizione per il trattamento della sindrome dell’ovaio policistico |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1992012706A1 (fr) * | 1991-01-23 | 1992-08-06 | University Of Virginia Patents Foundation | Procede permettant de reduire des taux eleves de glycemie chez l'homme |
WO2002094018A1 (fr) * | 2001-05-23 | 2002-11-28 | Insmed Incorporated | Compositions a base de d-chiro inositol et de composes hypolipidemiants et methodes therapeutiques les utilisant |
WO2007090289A1 (fr) * | 2006-02-09 | 2007-08-16 | National Research Council Of Canada | Combinaisons d'extraits botaniques pour favoriser la santé cardio-vasculaire |
US20080268039A1 (en) * | 2007-03-06 | 2008-10-30 | Soft Gel Technologies, Inc. | Loquat compositions |
US7476406B1 (en) * | 2004-05-17 | 2009-01-13 | Nse Products, Inc. | Multifaceted weight control system |
EP2070926A1 (fr) * | 2006-09-30 | 2009-06-17 | Shanghai Institute of Materia Medica, Chinese Academy of Sciences | Dérivés de 13,13a-dihydroberbérine, leur composition pharmaceutique et leurs utilisations |
WO2011061749A2 (fr) * | 2009-11-19 | 2011-05-26 | Ganga Raju Gokaraju | Agents dérivés d'holoptelea integrifolia et leurs compositions destinées à lutter contre le syndrome métabolique et les maladies associées |
-
2011
- 2011-07-22 WO PCT/ZA2011/000053 patent/WO2013016741A1/fr active Application Filing
-
2014
- 2014-02-19 ZA ZA2014/01237A patent/ZA201401237B/en unknown
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1992012706A1 (fr) * | 1991-01-23 | 1992-08-06 | University Of Virginia Patents Foundation | Procede permettant de reduire des taux eleves de glycemie chez l'homme |
WO2002094018A1 (fr) * | 2001-05-23 | 2002-11-28 | Insmed Incorporated | Compositions a base de d-chiro inositol et de composes hypolipidemiants et methodes therapeutiques les utilisant |
US7476406B1 (en) * | 2004-05-17 | 2009-01-13 | Nse Products, Inc. | Multifaceted weight control system |
WO2007090289A1 (fr) * | 2006-02-09 | 2007-08-16 | National Research Council Of Canada | Combinaisons d'extraits botaniques pour favoriser la santé cardio-vasculaire |
EP2070926A1 (fr) * | 2006-09-30 | 2009-06-17 | Shanghai Institute of Materia Medica, Chinese Academy of Sciences | Dérivés de 13,13a-dihydroberbérine, leur composition pharmaceutique et leurs utilisations |
US20080268039A1 (en) * | 2007-03-06 | 2008-10-30 | Soft Gel Technologies, Inc. | Loquat compositions |
WO2011061749A2 (fr) * | 2009-11-19 | 2011-05-26 | Ganga Raju Gokaraju | Agents dérivés d'holoptelea integrifolia et leurs compositions destinées à lutter contre le syndrome métabolique et les maladies associées |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2923701A1 (fr) | 2014-03-27 | 2015-09-30 | Neopharmed Gentili S.r.l. | Formulation pour le traitement et le contrôle du syndrome métabolique et des troubles corrélés |
ITUA20163025A1 (it) * | 2016-04-29 | 2017-10-29 | Sochim Int S P A | Composizione per il trattamento della sindrome dell’ovaio policistico |
WO2017187375A1 (fr) * | 2016-04-29 | 2017-11-02 | Sochim International S.P.A. | Composition pour le traitement du syndrome des ovaires polykystiques |
EP3448370B1 (fr) | 2016-04-29 | 2020-10-21 | Sochim International SpA | Composition pour le traitement du syndrome des ovaires polykystiques |
Also Published As
Publication number | Publication date |
---|---|
ZA201401237B (en) | 2015-08-26 |
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