WO2012153888A1 - Applicateur pour ultrasons focalisés de haute intensité - Google Patents

Applicateur pour ultrasons focalisés de haute intensité Download PDF

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Publication number
WO2012153888A1
WO2012153888A1 PCT/KR2011/003762 KR2011003762W WO2012153888A1 WO 2012153888 A1 WO2012153888 A1 WO 2012153888A1 KR 2011003762 W KR2011003762 W KR 2011003762W WO 2012153888 A1 WO2012153888 A1 WO 2012153888A1
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WO
WIPO (PCT)
Prior art keywords
ultrasonic
applicator
housing
hifu
treatment
Prior art date
Application number
PCT/KR2011/003762
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English (en)
Korean (ko)
Inventor
이창화
김대승
Original Assignee
알피니언메디칼시스템 주식회사
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Publication of WO2012153888A1 publication Critical patent/WO2012153888A1/fr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00—Ultrasound therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00—Ultrasound therapy
    • A61N7/02—Localised ultrasound hyperthermia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/42—Details of probe positioning or probe attachment to the patient
    • A61B8/4209—Details of probe positioning or probe attachment to the patient by using holders, e.g. positioning frames
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H23/00—Percussion or vibration massage, e.g. using supersonic vibration; Suction-vibration massage; Massage with moving diaphragms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/36—Image-producing devices or illumination devices not otherwise provided for
    • A61B90/37—Surgical systems with images on a monitor during operation
    • A61B2090/378—Surgical systems with images on a monitor during operation using ultrasound
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00—Ultrasound therapy
    • A61N2007/0078—Ultrasound therapy with multiple treatment transducers

Definitions

  • One embodiment of the present invention relates to an applicator for High Intensity Focused Ultrasound (HIFU). More specifically, by modifying the structure, it is possible to improve the treatment efficiency of HIFU treatment, shorten the procedure time, improve the treatment accuracy, improve the quality of the ultrasound image for the treatment, and simplify the HIFU device. It relates to an applicator for HIFU.
  • HIFU High Intensity Focused Ultrasound
  • HIFU treatment device uses ultrasound and penetrability and focus of ultrasound as a source of energy.
  • HIFU is radiated through the skin into cancer tissue in the human body from an applicator comprising a delivery medium.
  • an applicator comprising a delivery medium.
  • the ultrasound beam is focused within the tissue and is a roughly grain-shaped focal region (approximately 3 mm ⁇ 8 mm) with an intensity level above 0.1 W / cm 2 . Size) is formed.
  • the temperature rises instantaneously (within 0.1 to 5 seconds) (more than 70 degrees Celsius).
  • This thermal effect destroys cancer cells in the focal region and finally necrosis and destroys the entire cancer tissue, thereby realizing the purpose of treatment.
  • an ultrasonic vibrator capable of delivering an ultrasound beam of 1,000 to 10,000 W / cm 2 to a focus area is used, in contrast to diagnostic imaging ultrasound having an intensity level lower than 0.1 W / cm 2 .
  • Some energy of HIFU generated from this ultrasonic vibrator is transferred to the target area as thermal energy.
  • the amount of thermal energy delivered in this way can be supplied sufficiently strong to cauterize or necrosis the undesirable tissue by causing the tissue to rise to a temperature above 70 degrees Celsius without actually burning it.
  • the focal region can be strictly controlled to obtain necrosis of abnormal tissue or undesirable tissue of a small target region without damaging adjacent normal tissue.
  • Necrosis of tissue can also be achieved by mechanical action alone (ie, by the formation of cavities that lead to mechanical destruction of the tissue structure).
  • hemostasis may be performed using HIFU.
  • HIFU treatment is non-invasive.
  • HIFU can destroy cancer in the heart without surgery on the cancer site.
  • HIFU can provide additional methods of treatment that do not contradict this tendency by providing noninvasive surgical methods.
  • HIFU allows for transcutaneous treatment without incision, thereby avoiding blood loss and risk of infection.
  • HIFU treatment does not require anesthesia, reducing the complexity and cost of surgery.
  • Such HIFU treatment may be performed on hospital patients, and the greatest advantage is that the health care costs are further reduced while the convenience of the patients is improved.
  • FIG. 1 Examples of the general configuration of the prior art HIFU treatment apparatus are shown schematically in FIG. 1.
  • an example of the HIFU treatment apparatus includes an applicator 100, which includes an ultrasonic vibrator (piezoelectric ceramic), which is a means for generating HIFU, which acts as a means for irradiating HIFU, and the applicator 100.
  • Ultrasonic generator for generating an electrical signal for generating HIFU in the ultrasonic vibrator built in the), and installed in the applicator 100, a probe (Probe: 120) which acts as an image data collection means from the probe 120
  • an ultrasonic imaging apparatus for forming an image based on the image data of the apparatus.
  • HIFU treatment apparatus replaces the ultrasound imaging apparatus and the probe 120 in the above-described configuration, and replaces the applicator 100 and the treatment target with a gantry ( It may include an MR or CT imaging device that is received inside the gantry) to obtain an image.
  • a gantry It may include an MR or CT imaging device that is received inside the gantry
  • these HIFU treatment apparatus is a control device for controlling the irradiation of the HIFU and the irradiation stop by the applicator 100, the cooling of the ultrasonic vibrator in the applicator 100, and the ultrasonic delivery medium by circulating the ultrasonic delivery medium
  • An ultrasonic delivery medium circulator for cooling and degassing is provided.
  • the ultrasonic generator Under the control of the controller, the ultrasonic generator generates an electrical signal supplied to the ultrasonic vibrator of the applicator 100, and the ultrasonic vibrator of the applicator 100 converts the electrical signal received from the ultrasonic generator into physical vibration energy.
  • HIFU which is a physical vibration energy
  • the applicator 100 may be positioned close to the treatment area through manual position adjustment by an operator or automatic position adjustment through a robotic arm mechanism.
  • the ultrasonic delivery medium circulator also acts as a cooling means for cooling the ultrasonic vibrator of the applicator 100, which is a cooling device for cooling the ultrasonic delivery medium, a degassing device for removing air from the ultrasonic delivery medium, and an ultrasonic delivery medium.
  • HIFU treatment device for example, when the human body is treated using the exothermic action of HIFU, the HIFU is applied to the treatment area from the applicator 100 at a power of several tens to hundreds of watts (Watt) for several seconds. By continuously irradiating for several tens of seconds at, the treatment area is heated to a high temperature (eg, 70 degrees Celsius or more), which is cauterized to perform treatment.
  • a high temperature eg, 70 degrees Celsius or more
  • the ultrasonic vibrator 101 of the applicator 100 shown in FIG. 2 has a substantially hemispherical ultrasonic radiating surface 102.
  • the applicator 100 includes a substantially hemispherical membrane 103 having a sealing device 104 formed at an end thereof to be hermetically connected to the ultrasonic vibrator 101.
  • the membrane 103 covers and closes the ultrasonic radiating surface 102 of the ultrasonic vibrator 101.
  • the ultrasonic radiating surface 102 is formed in a hemispherical concave shape having a focal length radius for physical focusing of ultrasonic energy.
  • the ultrasonic delivery medium is filled between the membrane 103 and the ultrasonic radiating surface 102.
  • Unexplained reference numeral 105 denotes a push ring for connecting the membrane 103 to the ultrasonic vibrator 101.
  • a probe 120 connected to the ultrasound imaging apparatus (see FIG. 1) and collecting image data may be installed in the applicator 100.
  • the ultrasonic delivery medium may be water deaired.
  • One of the important components of all types of HIFU treatment devices is the means of coupling ultrasound energy into tissue. Good acoustic coupling is required to efficiently transfer ultrasonic energy from the ultrasonic vibrator 101 to the treatment area.
  • An ideal acoustic coupler is a homogenous medium with the same low attenuation and acoustic impedance as the tissue. Water has been commonly used as ultrasonic delivery medium in many HIFU therapeutic fields for desirable acoustic transmission properties.
  • the membrane 103 has a sound impedance similar to water and is made of a material having low ultrasonic wave transmission loss, perfect thermal conductivity, and good elasticity such as latex, relatively soft natural rubber, silicone rubber, and the like.
  • the applicator 100 having the above-described structure has the following disadvantages.
  • the ultrasonic vibrator or probe is to irradiate the human body with the ultrasonic transfer medium interposed therebetween, the distance between the ultrasonic vibrator or the probe and the treatment area will inevitably increase even if the ultrasonic transfer medium has a minimum thickness or distance. none.
  • the ultrasonic energy is attenuated, and as the treatment area increases according to the attenuation of the energy, the quality of the image decreases and the treatment efficiency decreases.
  • the abdomen of the human body should be pressed by an applicator to prevent image overlap by gas or bubbles in the organ.
  • the applicator is ultrasonically transmitted by a hemispherical elastic membrane. Because it accommodates, the patient's abdomen during the procedure can not be effectively compressed, the treatment efficiency is lowered, as well as causing burns in other parts of the internal wall of the organ.
  • the membrane is always reflected and reverberation, the probe receives the energy is damaged in severe cases, there is a problem that causes noise in the image data.
  • the efficiency of the ultrasonic energy is lowered. As a result, the treatment efficiency is lowered, and there is a problem that an image is generated at a portion other than the treatment area.
  • the present invention changes the structure of the applicator to have a generally flat ultrasonic vibrator, thereby improving the treatment efficiency of HIFU treatment, shortening the procedure time and improving the treatment accuracy, and improving the quality of the ultrasound image for the treatment.
  • An object of the present invention is to provide an applicator for HIFU that can be improved and can simplify the HIFU device.
  • HIFU applicator is characterized in that it comprises a housing and a plurality of ultrasonic vibrators arranged in a plurality of annular array on one flat surface of the housing.
  • HIFU applicator is a housing having a through hole in the center, a plurality of ultrasonic vibrators arranged in a plurality of annular array around the through hole on one flat surface of the housing, and the through hole It is characterized by including an imaging probe installed in the inside.
  • the structure of the applicator by changing the structure of the applicator to have a generally flat ultrasonic vibrator, it is possible to eliminate the ultrasonic delivery medium and the structure and the cooling system for accommodating the ultrasonic delivery medium. And the weight can be significantly reduced.
  • the ultrasonic vibrator of the applicator is directly in close contact with the human body, it is possible to increase the transfer efficiency by eliminating the factor that the ultrasonic energy is attenuated, thereby solving the problem of deterioration of image quality or treatment efficiency. There is an advantage to it.
  • the size of the applicator can be reduced to press the abdomen by minimizing the interference of the ribs, it is possible to position and focus at various angles regardless of the reflection or refraction of energy, There is an effect that the algorithm can be omitted.
  • the quality of the image acquired by the probe is improved, and the ultrasonic vibrator can be driven with low power, thereby improving the treatment efficiency, thereby reducing the procedure time and increasing patient convenience. Will be.
  • FIG. 1 is a schematic diagram showing examples of a general configuration of the HIFU treatment apparatus of the prior art.
  • FIG. 2 is a partial cross-sectional view of an example of an applicator used in prior art HIFU treatment devices.
  • FIG 3 is a schematic cross-sectional and bottom view of an applicator according to a first embodiment of the present invention.
  • FIG. 4 is a cross-sectional view showing the installation of the single ultrasonic vibrator shown in FIG.
  • FIG. 5 is a schematic cross-sectional view of an applicator according to a second embodiment of the present invention.
  • FIG. 3 is a schematic cross-sectional view and a bottom view thereof of the applicator according to the first embodiment of the present invention
  • Figure 4 is a cross-sectional view showing the installation of a single ultrasonic vibrator shown in FIG.
  • the HIFU applicator 300 includes a housing 301 and a plurality of annular arrays 321, 322, on one flat surface of the housing 301. 323, ...) and a plurality of ultrasonic vibrators 310 are arranged.
  • Housing 301 may be configured with various heat sinks to provide noninvasive treatment.
  • it may be formed of a substantially cylindrical member made of a metal such as aluminum.
  • the shape of the housing 301 is not limited thereto, and may include a plurality of ultrasonic vibrators 310 to be described below, and may be formed in various shapes that may be in direct contact with a patient to allow treatment.
  • a plurality of through holes 302 are formed on one flat surface of the housing 301 so as to communicate with the inside thereof, and a plurality of ultrasonic vibrators 310 may be inserted and installed in the through holes 302, respectively.
  • the ultrasonic vibrator 310 includes a piezoelectric element 311 and one or more acoustic matching layers 313 positioned on one side of the piezoelectric element 311 so as to appropriately form resonance characteristics.
  • the signal line 312 may be connected to transfer an electrical signal supplied from the ultrasonic generator (see FIG. 1) to the piezoelectric element 311 and to receive the signal from the piezoelectric element 311.
  • the piezoelectric element 311 may be made of a piezoelectric material such as a piezoelectric ceramic such as lead zirconate titanate (PZT), a crystal, a composite material, or the like.
  • a piezoelectric material such as a piezoelectric ceramic such as lead zirconate titanate (PZT), a crystal, a composite material, or the like.
  • the signal line 312 may be configured in the form of a wire, and may be arranged and connected in various ways, and thus detailed description thereof will be omitted.
  • one or more acoustic matching layers 313 may be adhesively fixed using an adhesive such as epoxy.
  • This acoustic bonding layer 313 may also be made of epoxy resin.
  • the acoustic matching layer 313 reduces the difference in acoustic impedance between the piezoelectric element 311 and the treatment region N (see FIG. 5) to obtain appropriate matching.
  • the plurality of ultrasonic vibrators 310 may be arranged in a plurality of annular arrays 321, 322, 323,... On one flat surface of the housing 301. These annular arrays 321, 322, 323,... Are each formed in separate sets and are physically and electrically separated.
  • the ultrasonic vibrators 310 which are installed on the outermost side, for example arranged in the first annular array 321, are inclined at an angle that can be directed to a focal point on the virtual center axis O of the housing 301. Is located.
  • the ultrasonic vibrators 310 arranged on the second annular array 322 closer to the center axis O than the first annular array 321 are also focused on the center axis O of the housing 301. It is inclined at an angle that can be directed to a point, and its inclined angle is inclined at a gentler angle than the inclined angle of the ultrasonic vibrators 310 arranged in the first annular array 321.
  • the ultrasonic vibrators 310 arranged in the annular array are gradually inclined to have a gentle angle. do.
  • the ultrasonic vibrator 310N which is positioned at the center of one flat side of the housing 301 and penetrates the central axis O, is positioned parallel to the flat one side plane of the housing 301.
  • the ultrasonic vibrators 310 arranged in one annular array 321, 322, 323,... are arranged at an angle that can be directed to a focusing point on the center axis O of the housing 301.
  • the HIFU treatment apparatus can achieve physical focusing of the ultrasound within a predetermined focal length.
  • the plurality of ultrasonic vibrators 310 may be driven by temporal control, such as controlling a change in driving timing of a typical ultrasonic vibrator. Therefore, the ultrasonic vibrator 310 may be dynamically controlled in time according to the change of the thermal state as well as the position, shape, and size of the treatment area N. Specifically, as shown schematically in FIG. 3, the ultrasonic beams emitted from the plurality of ultrasonic vibrators 310 are controlled by a method of controlling the transmission in response to the delay times T1, T2, T3,... The focus point may be focused on the above-described virtual center axis O. FIG.
  • a signal when a signal is applied to sequentially output ultrasonic waves by applying time delays calculated for each annular array 321, 322, 323,..., The focal length can be adjusted in the direction of the center axis O.
  • steering may also be performed in a direction perpendicular to the central axis O.
  • the front end of the plurality of ultrasonic vibrator 310 is connected, it can be seen that the front end is located on the virtual plane.
  • the oscillation portion of the ultrasonic energy in the applicator 300 used in the HIFU treatment apparatus is made into a substantially flat form (although substantially similar to the sawtooth shape due to irregularities in the cross-sectional shape) and directly to the human body (M: FIG. 5).
  • M the human body
  • the robotic arm mechanism includes an arm that is coupled to the housing 301 to operate electrically and mechanically.
  • the housing 301 may be installed in a manner such as bolting, chucking, clamping, or the like.
  • the arm can be driven and controlled by a controller (see FIG. 1).
  • a plurality of piezoelectric elements 311 having a housing 301 and a predetermined acoustic matching layer 313 are separately manufactured, and then the signal lines 312 are connected to each piezoelectric element 311 by soldering, for example. .
  • the ultrasonic vibrator 310 having the piezoelectric element 311 and the signal line 312 assembled therein is inserted into each of the plurality of through holes 302 formed in the housing 301 and then fixed by bonding or the like.
  • a waterproof coating process for tightly sealing a gap between the through hole 302 and the ultrasonic vibrator 310 of the housing 301 may be performed.
  • the structure of the applicator by changing the structure of the applicator to have a generally flat ultrasonic vibrator, it is possible to eliminate the ultrasonic delivery medium and the structure and the cooling system accommodating the ultrasonic delivery medium. There is an advantage that no design is required. As a result, the size and weight of the entire treatment device as well as the applicator can be greatly reduced, greatly expanding the possibility of developing as a portable device, and easy to store and maintain, and to eliminate the use of consumable materials. Will be.
  • FIG. 5 is a schematic cross-sectional view of an applicator according to a second embodiment of the present invention.
  • the HIFU applicator 500 includes a housing 501 having a through hole 503 in the center, and a through hole 503 at one flat surface of the housing 501. ) Includes a plurality of ultrasonic vibrators 510 arranged in a plurality of annular arrays, and an imaging probe 120 installed in the through hole 503.
  • the second embodiment of the present invention relates to an applicator 500 incorporating a therapeutic ultrasonic vibrator 510 and an imaging probe 120 for image acquisition and monitoring.
  • the imaging probe 120 connected to the ultrasonic vibrator 510 via a cable includes a beam forming control unit.
  • the imaging probe 120 is operated to scan a region of interest including the treatment region N of the human body M by ultrasound.
  • the returned signal is received by the imaging probe 120 and then transmitted to the beamforming control unit to generate an ultrasound image of the region of interest including the treatment region N.
  • the generated image may be displayed on a display (not shown) so that the operator properly positions the applicator 500, that is, the therapeutic ultrasonic vibrator 510, with respect to the treatment area N before the actual treatment is started.
  • a display not shown
  • the imaging probe 120 may be installed in various ways in the through hole 503 of the housing 501, and may be accommodated in a separate carrier so that the carrier may be inserted into the through hole 503.
  • the present specification has been described mainly for the applicator for the treatment, it should be noted that the present invention is not limited to this use.
  • the HIFU applicator according to the present invention can be applied to other industries.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Heart & Thoracic Surgery (AREA)
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Abstract

La présente invention concerne, par l'un de ses modes de réalisation, un applicateur destiné aux ultrasons focalisés de haute intensité ou "HIFU" (High Intensity Focused Ultrasound). Cet applicateur comprend un logement et une pluralité de vibreurs ultrasonores. Les vibreurs de cette pluralité de vibreurs ultrasonores sont montés en une pluralité de matrices annulaires sur une face plate du logement, de façon à renforcer l'efficacité du traitement HIFU, à diminuer la durée de la procédure, à renforcer la précision du traitement, et à simplifier le dispositif HIFU.
PCT/KR2011/003762 2011-05-12 2011-05-23 Applicateur pour ultrasons focalisés de haute intensité WO2012153888A1 (fr)

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KR10-2011-0044682 2011-05-12
KR1020110044682A KR101259381B1 (ko) 2011-05-12 2011-05-12 고강도 집속 초음파용 어플리케이터

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110478632A (zh) * 2019-08-30 2019-11-22 深圳先进技术研究院 超声针灸装置

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014193013A1 (fr) * 2013-05-31 2014-12-04 알피니언메디칼시스템 주식회사 Transducteur ultrasonore ayant une fonction de refroidissement
KR101492608B1 (ko) * 2013-05-31 2015-02-11 알피니언메디칼시스템 주식회사 이미지 품질을 개선하기 위한 트랜스듀서 구조
KR20150064598A (ko) * 2013-12-03 2015-06-11 주식회사 코러스트 초음파 심부 열 발생 장치
KR101616925B1 (ko) * 2015-10-17 2016-04-29 고재석 생체 활성화 조절장치

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5722411A (en) * 1993-03-12 1998-03-03 Kabushiki Kaisha Toshiba Ultrasound medical treatment apparatus with reduction of noise due to treatment ultrasound irradiation at ultrasound imaging device
JP2004097534A (ja) * 2002-09-10 2004-04-02 Toshiba Corp 超音波照射装置
US6773408B1 (en) * 1997-05-23 2004-08-10 Transurgical, Inc. MRI-guided therapeutic unit and methods
JP2004267655A (ja) * 2003-03-12 2004-09-30 Toshiba Corp 超音波治療装置及び超音波治療方法
JP2007144225A (ja) * 1997-03-03 2007-06-14 Toshiba Corp 超音波治療装置
JP2011514181A (ja) * 2008-02-01 2011-05-06 メディシス テクノロジーズ コーポレイション 超音波システムを伴う使用のための治療ヘッド

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5722411A (en) * 1993-03-12 1998-03-03 Kabushiki Kaisha Toshiba Ultrasound medical treatment apparatus with reduction of noise due to treatment ultrasound irradiation at ultrasound imaging device
JP2007144225A (ja) * 1997-03-03 2007-06-14 Toshiba Corp 超音波治療装置
US6773408B1 (en) * 1997-05-23 2004-08-10 Transurgical, Inc. MRI-guided therapeutic unit and methods
JP2004097534A (ja) * 2002-09-10 2004-04-02 Toshiba Corp 超音波照射装置
JP2004267655A (ja) * 2003-03-12 2004-09-30 Toshiba Corp 超音波治療装置及び超音波治療方法
JP2011514181A (ja) * 2008-02-01 2011-05-06 メディシス テクノロジーズ コーポレイション 超音波システムを伴う使用のための治療ヘッド

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110478632A (zh) * 2019-08-30 2019-11-22 深圳先进技术研究院 超声针灸装置

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