WO2012144711A3 - 층꽃풀 추출물 또는 이로부터 분리된 화합물을 함유하는 간독성 질환 예방 및 치료용 조성물 - Google Patents

층꽃풀 추출물 또는 이로부터 분리된 화합물을 함유하는 간독성 질환 예방 및 치료용 조성물 Download PDF

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Publication number
WO2012144711A3
WO2012144711A3 PCT/KR2011/008964 KR2011008964W WO2012144711A3 WO 2012144711 A3 WO2012144711 A3 WO 2012144711A3 KR 2011008964 W KR2011008964 W KR 2011008964W WO 2012144711 A3 WO2012144711 A3 WO 2012144711A3
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WO
WIPO (PCT)
Prior art keywords
extracts
preventing
isolated therefrom
compound isolated
composition containing
Prior art date
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PCT/KR2011/008964
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English (en)
French (fr)
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WO2012144711A2 (ko
Inventor
진창배
김형자
이용섭
정서윤
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한국과학기술연구원
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Application filed by 한국과학기술연구원 filed Critical 한국과학기술연구원
Publication of WO2012144711A2 publication Critical patent/WO2012144711A2/ko
Publication of WO2012144711A3 publication Critical patent/WO2012144711A3/ko

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/85—Verbenaceae (Verbena family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Organic Chemistry (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

본 발명은 층꽃풀 추출물, 이의 분획물 또는 이로부터 분리된 화합물을 함유하는 간독성 질환 예방 및 치료용 조성물에 관한 것이다. 본 발명의 층꽃풀(Caryopteris incana) 추출물, 이의 분획물 및 이로부터 분리된 화합물은 제3급-부틸히드로퍼옥시드(t-BHP, tertiary-butyl hydroperoxide)와 같은 독성 물질에 의하여 간 독성이 유발되었을 때 간세포 보호 효과가 우수하므로 간 질환의 예방 및 치료에 탁월한 효과를 기대할 수 있다.
PCT/KR2011/008964 2011-04-20 2011-11-23 층꽃풀 추출물 또는 이로부터 분리된 화합물을 함유하는 간독성 질환 예방 및 치료용 조성물 WO2012144711A2 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2011-0036866 2011-04-20
KR1020110036866A KR101321879B1 (ko) 2011-04-20 2011-04-20 층꽃풀 추출물 또는 이로부터 분리된 화합물을 함유하는 간독성 질환 예방 및 치료용 조성물

Publications (2)

Publication Number Publication Date
WO2012144711A2 WO2012144711A2 (ko) 2012-10-26
WO2012144711A3 true WO2012144711A3 (ko) 2013-03-07

Family

ID=47041997

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2011/008964 WO2012144711A2 (ko) 2011-04-20 2011-11-23 층꽃풀 추출물 또는 이로부터 분리된 화합물을 함유하는 간독성 질환 예방 및 치료용 조성물

Country Status (2)

Country Link
KR (1) KR101321879B1 (ko)
WO (1) WO2012144711A2 (ko)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015079413A2 (en) * 2013-11-28 2015-06-04 Yeda Research And Development Co. Ltd. Synaptojanin-2 inhibitors and uses thereof
KR20190086235A (ko) 2018-01-12 2019-07-22 경북대학교 산학협력단 젖산균으로 고체발효한 층꽃나무 발효 추출물을 유효 성분으로 함유하는 항염증용 조성물 및 그 제조방법
KR102161319B1 (ko) 2020-03-12 2020-10-05 경북대학교 산학협력단 젖산균으로 고체발효한 층꽃나무 발효 추출물을 유효 성분으로 함유하는 항염증용 조성물 및 그 제조방법

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DA PENG ZHAO ET AL.: "Iridoid glucoside, (3R)-oct-1-en-3-ol glycosides, and phenylethanoid from the aerial parts of Caryopteris incana", J. NAT. MED., vol. 63, 2009, pages 241 - 247 *
JIAN-JUN GAO ET AL.: "Radical Scavenging Activity of Phenylpropanoid Glycosides in Caryopteris incana", BIOSCI. BIOTECHNOL. BIOCHEM., vol. 63, no. 6, 1999, pages 983 - 988 *
JIANJUN GAO ET AL.: "Three New Phenylethanoid Glycosides from Caryopteris incana and TheirAntioxidative Activity", CHEM. PHARM. BULL., vol. 48, no. 7, 2000, pages 1075 - 1078 *

Also Published As

Publication number Publication date
WO2012144711A2 (ko) 2012-10-26
KR20120119105A (ko) 2012-10-30
KR101321879B1 (ko) 2013-10-28

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