WO2012135731A3 - Alcohol production from recombinant microorganisms - Google Patents

Alcohol production from recombinant microorganisms Download PDF

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Publication number
WO2012135731A3
WO2012135731A3 PCT/US2012/031628 US2012031628W WO2012135731A3 WO 2012135731 A3 WO2012135731 A3 WO 2012135731A3 US 2012031628 W US2012031628 W US 2012031628W WO 2012135731 A3 WO2012135731 A3 WO 2012135731A3
Authority
WO
WIPO (PCT)
Prior art keywords
alcohol production
recombinant microorganisms
microorganisms
organisms
methods
Prior art date
Application number
PCT/US2012/031628
Other languages
French (fr)
Other versions
WO2012135731A2 (en
Inventor
James C. Liao
Yasumasa Dekishima
Original Assignee
The Regents Of The University Of California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Regents Of The University Of California filed Critical The Regents Of The University Of California
Publication of WO2012135731A2 publication Critical patent/WO2012135731A2/en
Publication of WO2012135731A3 publication Critical patent/WO2012135731A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y203/00—Acyltransferases (2.3)
    • C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12Y203/01009—Acetyl-CoA C-acetyltransferase (2.3.1.9)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y203/00—Acyltransferases (2.3)
    • C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12Y203/01016—Acetyl-CoA C-acyltransferase (2.3.1.16)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel

Abstract

Provided are microorganisms that catalyze the synthesis of biofuels from a suitable carbon dioxide. Also provided are methods of generating such organisms and methods of synthesizing biofuels using such organisms. Provided are microorganisms comprising non- naturally occurring metabolic pathway for the production of higher alcohols.
PCT/US2012/031628 2011-04-01 2012-03-30 Alcohol production from recombinant microorganisms WO2012135731A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161471029P 2011-04-01 2011-04-01
US61/471,029 2011-04-01

Publications (2)

Publication Number Publication Date
WO2012135731A2 WO2012135731A2 (en) 2012-10-04
WO2012135731A3 true WO2012135731A3 (en) 2012-11-29

Family

ID=46932411

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2012/031628 WO2012135731A2 (en) 2011-04-01 2012-03-30 Alcohol production from recombinant microorganisms

Country Status (1)

Country Link
WO (1) WO2012135731A2 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9102960B2 (en) * 2011-12-16 2015-08-11 Invista North America S.á.r.l. Methods of producing 6-carbon chemicals via CoA-dependent carbon chain elongation associated with carbon storage
US9102958B2 (en) * 2011-12-16 2015-08-11 Invista North America S.á.r.l. Methods of producing 6-carbon chemicals via CoA-dependent carbon chain elongation associated with carbon storage
BR112016012712B1 (en) 2013-12-12 2023-10-03 Dow Global Technologies Llc PROCESS FOR PREPARING A C7-C11 2-KETO ACID, MICROBIAL ORGANISM AND GENETICALLY MODIFIED LEUB' POLYPEPTIDE
JP6755515B2 (en) 2014-08-04 2020-09-16 国立大学法人東京工業大学 Method for producing copolymerized polyhydroxyalkanoic acid from sugar raw material
WO2016094604A1 (en) 2014-12-10 2016-06-16 Dow Global Technologies Llc Genetically modified phenylpyruvate decarboxylase, processes to prepare, and uses thereof
EP3365427B1 (en) 2015-10-23 2020-08-19 Metabolic Explorer Microorganism modified for the assimilation of levulinic acid
WO2018063423A1 (en) 2016-09-30 2018-04-05 Dow Global Technologies Llc Processes to prepare elongated 2-ketoacids and c5-c10 compounds therefrom via genetic modifications to microbial metabolic pathways
CN111201321A (en) 2017-09-29 2020-05-26 陶氏环球技术有限责任公司 Genetically modified isopropylmalate isomerase complex and method for preparing elongated 2-keto acids and C using same5-C10Method for preparing compounds
US11466296B2 (en) * 2019-07-22 2022-10-11 Ut-Battelle, Llc Genetically-modified bacteria for conversion of organic compounds to butanol and methods of use
CN114774338B (en) * 2022-03-29 2023-08-08 北京航空航天大学 Probiotics for producing butyric acid, construction method and application thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080274524A1 (en) * 2007-05-02 2008-11-06 Bramucci Michael G Method for the production of 1-butanol
US20090111154A1 (en) * 2007-04-04 2009-04-30 The Regents Of The University Of California Butanol production by recombinant microorganisms
WO2009105733A2 (en) * 2008-02-23 2009-08-27 James Weifu Lee Designer organisms for photobiological butanol production from carbon dioxide and water
WO2010101651A1 (en) * 2009-03-06 2010-09-10 Massachusetts Institute Of Technology Microbial production of 3-hydroxyacids from glucose and glycolate

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090111154A1 (en) * 2007-04-04 2009-04-30 The Regents Of The University Of California Butanol production by recombinant microorganisms
US20080274524A1 (en) * 2007-05-02 2008-11-06 Bramucci Michael G Method for the production of 1-butanol
WO2009105733A2 (en) * 2008-02-23 2009-08-27 James Weifu Lee Designer organisms for photobiological butanol production from carbon dioxide and water
WO2010101651A1 (en) * 2009-03-06 2010-09-10 Massachusetts Institute Of Technology Microbial production of 3-hydroxyacids from glucose and glycolate

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
ATSUMI, S ET AL., CURR. OPIN. BIOTECHNOL, vol. 19, 2008, pages 414 - 419 *
ATSUMI, S. ET AL., METABOLIC ENGINEERING, vol. 10, 2008, pages 305 - 311 *
DEKISHIMA, Y ET AL., vol. 133, 2011, pages 11399 - 11401 *
TSENG, H. C: "Production of Pentanol in Metabolically Engineered Escherichia coli", PH.D. THESIS, MASSACUSETTS INSTITUTE OF TECHNOLOGY, 2011 *

Also Published As

Publication number Publication date
WO2012135731A2 (en) 2012-10-04

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