WO2012134063A3 - 구강 세균감염성질환 원인균 검출용 프라이머 및 이의 용도 - Google Patents

구강 세균감염성질환 원인균 검출용 프라이머 및 이의 용도 Download PDF

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Publication number
WO2012134063A3
WO2012134063A3 PCT/KR2012/001424 KR2012001424W WO2012134063A3 WO 2012134063 A3 WO2012134063 A3 WO 2012134063A3 KR 2012001424 W KR2012001424 W KR 2012001424W WO 2012134063 A3 WO2012134063 A3 WO 2012134063A3
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WIPO (PCT)
Prior art keywords
infectious diseases
pathogenic bacteria
primer
bacterial infectious
oral bacterial
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PCT/KR2012/001424
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English (en)
French (fr)
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WO2012134063A2 (ko
Inventor
국중기
박순낭
임윤경
김민정
조유진
임채광
김동춘
박한오
Original Assignee
조선대학교산학협력단
(주)바이오니아
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Priority claimed from KR1020120018161A external-priority patent/KR101385733B1/ko
Application filed by 조선대학교산학협력단, (주)바이오니아 filed Critical 조선대학교산학협력단
Publication of WO2012134063A2 publication Critical patent/WO2012134063A2/ko
Publication of WO2012134063A3 publication Critical patent/WO2012134063A3/ko

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6851—Quantitative amplification
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
    • Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

본 발명은 구강 세균감염성질환 원인균 검출용 프라이머 및 이의 용도에 관한 것으로, 보다 구체적으로 구강 세균감염성질환을 일으키는 원인균을 정성 및 정량적으로 검출할 수 있으며, 종-특이성이 뛰어난 구강 세균감염성질환 원인균 검출용 프라이머, 검출용 조성물, 키트 및 마이크로어레이에 관한 것이다. 본 발명에 따른 구강 세균감염성질환 원인균 검출용 프라이머는 민감도가 높고 종-특이성이 뛰어나며, 다양한 세균에 의한 구강 내 치주 조직의 감염 여부를 신속하고 간단하게 검출, 탐지할 수 있으며, 구강 세균감염성질환을 일으키는 원인균을 정성 및 정량적으로 검출할 수 있는 효과가 있다. 또한, 세균학적 예후평가를 규명하는 도구로 이용될 수 있다.
PCT/KR2012/001424 2011-03-29 2012-02-24 구강 세균감염성질환 원인균 검출용 프라이머 및 이의 용도 WO2012134063A2 (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
KR20110028406 2011-03-29
KR10-2011-0028406 2011-03-29
KR1020120018161A KR101385733B1 (ko) 2011-03-29 2012-02-22 구강 세균감염성질환 원인균 검출용 프라이머 및 이의 용도
KR10-2012-0018161 2012-02-22

Publications (2)

Publication Number Publication Date
WO2012134063A2 WO2012134063A2 (ko) 2012-10-04
WO2012134063A3 true WO2012134063A3 (ko) 2012-11-29

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2012/001424 WO2012134063A2 (ko) 2011-03-29 2012-02-24 구강 세균감염성질환 원인균 검출용 프라이머 및 이의 용도

Country Status (1)

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WO (1) WO2012134063A2 (ko)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015188178A1 (en) 2014-06-06 2015-12-10 The Regents Of The University Of Michigan Compositions and methods for characterizing and diagnosing periodontal disease
EP3966330A2 (en) * 2019-05-06 2022-03-16 The Procter & Gamble Company Detection of microbial endotoxins in oral samples using aptamers
CN114317783B (zh) * 2021-12-08 2023-07-28 上海锐翌医学检验实验室有限公司 龋齿标志微生物及其应用

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
ALIYU, S. H. ET AL.: "Real-time PCR investigation into the importance of Fusobacterium necrophorum as a cause of acute pharyngitis in general practice", JOURNAL OF MEDICAL MICROBIOLOGY., vol. 53, October 2004 (2004-10-01), pages 1029 - 1035 *
HENSSGE, U. ET AL.: "Emended description of Actinomyces naeslundii and descriptions of Actinomyces oris sp. nov. and Actinomyces johnsonii sp. no., previously identified as Actinomyces naeslundii genospecies 1, 2 and WVA 963", INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY., vol. 59, March 2009 (2009-03-01), pages 509 - 516 *
PARK, S. N. ET AL.: "Development of quantitative real-time PCR primers for the detection of Aggregatibacter actinomycetemcomitans", INTERNATIONAL JOURNAL OF ORAL BIOLOGY., vol. 36, no. L, 31 March 2011 (2011-03-31), pages 1 - 6 *
PARK, S. N. ET AL.: "Development ofPorphyromonas gingivalis-specific quantitative real- time PCR primers based on the nucleotide sequence ofrpoB", JOURNAL OF MICROBIOLOGY., vol. 49, no. 2, 3 May 2011 (2011-05-03), pages 315 - 319 *
TANG, G. ET AL.: "Direct detection of Actinomyces spp. from infected root canals in a Chinese population: a study using PCR-based, oligonucleotide-DNA hybridization technique", JOURNAL OF DENTISTRY., vol. 31, no. 8, November 2003 (2003-11-01), pages 559 - 568 *
TRAN-HUNG, L. ET AL.: "A new method to extract dental pulp DNA: application to universal detection of bacteria", PLOS ONE., vol. 2, no. 10, 24 October 2007 (2007-10-24), pages E1062 *

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