WO2012125734A3 - Diagnostic method and breath testing device - Google Patents

Diagnostic method and breath testing device Download PDF

Info

Publication number
WO2012125734A3
WO2012125734A3 PCT/US2012/029087 US2012029087W WO2012125734A3 WO 2012125734 A3 WO2012125734 A3 WO 2012125734A3 US 2012029087 W US2012029087 W US 2012029087W WO 2012125734 A3 WO2012125734 A3 WO 2012125734A3
Authority
WO
WIPO (PCT)
Prior art keywords
testing device
diagnostic method
breath testing
breath
fib
Prior art date
Application number
PCT/US2012/029087
Other languages
French (fr)
Other versions
WO2012125734A2 (en
Inventor
Anastasia Rigas
Original Assignee
Anastasia Rigas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Anastasia Rigas filed Critical Anastasia Rigas
Priority to EP12757976.1A priority Critical patent/EP2685891A4/en
Publication of WO2012125734A2 publication Critical patent/WO2012125734A2/en
Publication of WO2012125734A3 publication Critical patent/WO2012125734A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/08—Detecting, measuring or recording devices for evaluating the respiratory organs
    • A61B5/082—Evaluation by breath analysis, e.g. determination of the chemical composition of exhaled breath
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/42—Detecting, measuring or recording for evaluating the gastrointestinal, the endocrine or the exocrine systems
    • A61B5/4216—Diagnosing or evaluating gastrointestinal ulcers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/497—Physical analysis of biological material of gaseous biological material, e.g. breath
    • G01N33/4975—Physical analysis of biological material of gaseous biological material, e.g. breath other than oxygen, carbon dioxide or alcohol, e.g. organic vapours
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/84—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving inorganic compounds or pH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02—Details of sensors specially adapted for in-vivo measurements
    • A61B2562/0285—Nanoscale sensors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/08—Detecting, measuring or recording devices for evaluating the respiratory organs
    • A61B5/097—Devices for facilitating collection of breath or for directing breath into or through measuring devices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/02—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance
    • G01N27/04—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating resistance
    • G01N27/12—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating resistance of a solid body in dependence upon absorption of a fluid; of a solid body in dependence upon reaction with a fluid, for detecting components in the fluid
    • G01N27/125—Composition of the body, e.g. the composition of its sensitive layer
    • G01N27/127—Composition of the body, e.g. the composition of its sensitive layer comprising nanoparticles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/0004—Gaseous mixtures, e.g. polluted air
    • G01N33/0009—General constructional details of gas analysers, e.g. portable test equipment
    • G01N33/0027—General constructional details of gas analysers, e.g. portable test equipment concerning the detector
    • G01N33/0036—General constructional details of gas analysers, e.g. portable test equipment concerning the detector specially adapted to detect a particular component
    • G01N33/005—H2

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physiology (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Endocrinology (AREA)
  • Inorganic Chemistry (AREA)
  • Pulmonology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Rehabilitation Therapy (AREA)
  • Rheumatology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analyzing Materials By The Use Of Fluid Adsorption Or Reactions (AREA)

Abstract

The present invention relates to a diagnostic method and breath-testing device for the diagnosis of Celiac Disease or other gastrointestinal malabsorption in adults and children, and uses a hydrogen selective sensor in the form of a ZnO nanowire-based sensor fabricated using a focused ion beam (FIB/SEM) instrument or a thin film.
PCT/US2012/029087 2011-03-14 2012-03-14 Diagnostic method and breath testing device WO2012125734A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP12757976.1A EP2685891A4 (en) 2011-03-14 2012-03-14 Diagnostic method and breath testing device

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161452507P 2011-03-14 2011-03-14
US61/452,507 2011-03-14

Publications (2)

Publication Number Publication Date
WO2012125734A2 WO2012125734A2 (en) 2012-09-20
WO2012125734A3 true WO2012125734A3 (en) 2014-03-13

Family

ID=46831323

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2012/029087 WO2012125734A2 (en) 2011-03-14 2012-03-14 Diagnostic method and breath testing device

Country Status (2)

Country Link
EP (1) EP2685891A4 (en)
WO (1) WO2012125734A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9678058B2 (en) 2010-09-03 2017-06-13 Anastasia Rigas Diagnostic method and breath testing device
US10401318B2 (en) 2011-03-14 2019-09-03 Anastasia Rigas Breath analyzer and breath test methods
CN104458886B (en) * 2014-12-09 2018-01-16 江苏师范大学 A kind of nanometer respiration transducer and preparation method thereof
EP3893736B1 (en) * 2018-12-10 2023-08-02 Anastasia Rigas Breath analyzer devices and breath test methods

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7522040B2 (en) * 2004-04-20 2009-04-21 Nanomix, Inc. Remotely communicating, battery-powered nanostructure sensor devices
US20100209507A1 (en) * 1999-08-11 2010-08-19 Cedars-Sinai Medical Center Methods of diagnosing and treating small intestinal bacterial overgrowth (sibo) and sibo-related conditions

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7104963B2 (en) * 2002-01-22 2006-09-12 University Of Florida Research Foundation, Inc. Method and apparatus for monitoring intravenous (IV) drug concentration using exhaled breath
US7791150B1 (en) * 2004-09-25 2010-09-07 University Of Central Florida Research Foundation, Inc. Room temperature hydrogen sensor
WO2008153593A1 (en) * 2006-11-10 2008-12-18 Bourns Inc. Nanomaterial-based gas sensors

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100209507A1 (en) * 1999-08-11 2010-08-19 Cedars-Sinai Medical Center Methods of diagnosing and treating small intestinal bacterial overgrowth (sibo) and sibo-related conditions
US7522040B2 (en) * 2004-04-20 2009-04-21 Nanomix, Inc. Remotely communicating, battery-powered nanostructure sensor devices

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
LUPAN ET AL.: "Selective hydrogen gas nanosensor using individual ZnO nanowire with fast response at room temperature", SENS. ACTUATORS B: CHEM., vol. 144, no. 1, 2009, pages 56 - 66, XP026861996 *

Also Published As

Publication number Publication date
EP2685891A4 (en) 2015-03-18
WO2012125734A2 (en) 2012-09-20
EP2685891A2 (en) 2014-01-22

Similar Documents

Publication Publication Date Title
WO2011135194A3 (en) Method for diagnosing risk of type 1 diabetes and for preventing onset of type 1 diabetes
WO2014159822A3 (en) Human antibodies to respiratory syncytial virus f protein and methods of use thereof
WO2012125734A3 (en) Diagnostic method and breath testing device
EP3919174A3 (en) Integrated multiplex target analysis
WO2012054639A3 (en) Nmr systems and methods for the rapid detection of analytes
WO2014090460A3 (en) Method and device for determining the total mass of an electrically drivable vehicle
EP2164725A4 (en) An improved led device for wide beam generation and method of making the same
WO2012160527A3 (en) Integrity evaluation system in an implantable hearing prosthesis
WO2011129542A3 (en) Device and method for processing virtual worlds
WO2011063350A3 (en) Methods and compositions for producing squalene using yeast
WO2011056899A3 (en) Chimeric rsv-f polypeptide and lentivirus or alpha-retrovirus gag-based vlps
GB2497697A (en) Magnetic nanoparticle detection across a membrane
WO2012065117A3 (en) Oral cancer point of care diagnostics
WO2012047267A3 (en) Polyvalent immunogen
WO2010090767A3 (en) Enhancing biocompatibility of a medical device
WO2013151421A3 (en) Integrated optical and charged particle inspection apparatus
WO2012047792A3 (en) Device and method for breath analysis using acoustic resonance flow rate
PL2533868T3 (en) An attachment device for attachment to a membrane, e.g. of a balloon, without puncturing the membrane
WO2012004813A3 (en) A system and method for conducting high stake examination using integrated technology platform
MX2014015088A (en) Anti-tofacitinib antibodies and uses thereof for drug monitoring.
WO2013073105A3 (en) Information processing apparatus, information processing method and program
WO2012122288A3 (en) Visualization balloon and method of use thereof
WO2013167727A3 (en) Method for determining arthritis relapse risk
WO2014127328A3 (en) Methods and compositions for amplified electrochemiluminescence detection
GB2515713A (en) Methods, packaging and apparatus for collection of biological samples

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 12757976

Country of ref document: EP

Kind code of ref document: A2

WWE Wipo information: entry into national phase

Ref document number: 2012757976

Country of ref document: EP