WO2012108650A3 - 뇌졸중의 치료제 또는 진단제로서 프로테이나아제-3에 대한 단클론 항체의 용도 - Google Patents

뇌졸중의 치료제 또는 진단제로서 프로테이나아제-3에 대한 단클론 항체의 용도 Download PDF

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Publication number
WO2012108650A3
WO2012108650A3 PCT/KR2012/000854 KR2012000854W WO2012108650A3 WO 2012108650 A3 WO2012108650 A3 WO 2012108650A3 KR 2012000854 W KR2012000854 W KR 2012000854W WO 2012108650 A3 WO2012108650 A3 WO 2012108650A3
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WO
WIPO (PCT)
Prior art keywords
proteinase
stroke
monoclonal antibody
agent
therapeutic agent
Prior art date
Application number
PCT/KR2012/000854
Other languages
English (en)
French (fr)
Other versions
WO2012108650A2 (ko
Inventor
신찬영
김수현
배수영
권경자
Original Assignee
건국대학교 산학협력단
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 건국대학교 산학협력단 filed Critical 건국대학교 산학협력단
Publication of WO2012108650A2 publication Critical patent/WO2012108650A2/ko
Publication of WO2012108650A3 publication Critical patent/WO2012108650A3/ko

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

본 발명은 뇌졸중의 치료제 또는 진단제로서 프로테이나아제-3에 대한 단클론 항체의 용도에 관한 것이다.
PCT/KR2012/000854 2011-02-10 2012-02-06 뇌졸중의 치료제 또는 진단제로서 프로테이나아제-3에 대한 단클론 항체의 용도 WO2012108650A2 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2011-0012057 2011-02-10
KR1020110012057A KR101262251B1 (ko) 2011-02-10 2011-02-10 뇌졸중의 치료제 또는 진단제로서 프로테이나아제-3에 대한 단클론 항체의 용도

Publications (2)

Publication Number Publication Date
WO2012108650A2 WO2012108650A2 (ko) 2012-08-16
WO2012108650A3 true WO2012108650A3 (ko) 2012-10-26

Family

ID=46639035

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2012/000854 WO2012108650A2 (ko) 2011-02-10 2012-02-06 뇌졸중의 치료제 또는 진단제로서 프로테이나아제-3에 대한 단클론 항체의 용도

Country Status (2)

Country Link
KR (1) KR101262251B1 (ko)
WO (1) WO2012108650A2 (ko)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104297489A (zh) * 2014-08-20 2015-01-21 苏州和锐医药科技有限公司 一种抗pr3-anca抗体检测试纸的制备方法及用途
FR3102175B1 (fr) * 2019-10-18 2021-10-01 Univ Tours Nouveaux anticorps monoclonaux therapeutiques humains et leurs utilisations

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DATABASE NCBI 19 March 1999 (1999-03-19), accession no. M 002777 *
DOMINIQUE BORIES ET AL.: "Down-regulation of a serine protease, myeloblastin, causes growth arrest and differentiation of promyelocytic leukemia cells", CELL, vol. 59, no. 6, 1989, pages 959 - 968 *
W.-J. MAYET ET AL.: "Antibodies to proteinase 3 increase adhesion of neutrophils to human endothelial cells", CLIN. EXP. IMMUNOL., vol. 94, no. 3, 1993, pages 440 - 446 *
Y. M. VAN DER GELD ET AL.: "Characterization of monoclonal antibodies to proteinase 3 (PR3) as candidate tools for epitope mapping of human anti-PR3 autoantibodies", CLIN. EXP. IMMUNOL., vol. 118, no. 3, 1999, pages 487 - 496 *

Also Published As

Publication number Publication date
WO2012108650A2 (ko) 2012-08-16
KR20120091936A (ko) 2012-08-20
KR101262251B1 (ko) 2013-05-08

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