WO2012104416A1 - Appareil de vérification de thérapie par particules - Google Patents

Appareil de vérification de thérapie par particules Download PDF

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Publication number
WO2012104416A1
WO2012104416A1 PCT/EP2012/051866 EP2012051866W WO2012104416A1 WO 2012104416 A1 WO2012104416 A1 WO 2012104416A1 EP 2012051866 W EP2012051866 W EP 2012051866W WO 2012104416 A1 WO2012104416 A1 WO 2012104416A1
Authority
WO
WIPO (PCT)
Prior art keywords
slit
target
shaped portion
collimator
scintillator
Prior art date
Application number
PCT/EP2012/051866
Other languages
English (en)
Inventor
Damien Prieels
Frédéric Stichelbaut
Julien SMEETS
Alain Dubus
Jean-Claude DEHAES
Original Assignee
Ion Beam Applications S.A.
Universite Libre De Bruxelles
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ion Beam Applications S.A., Universite Libre De Bruxelles filed Critical Ion Beam Applications S.A.
Priority to EP12702533.6A priority Critical patent/EP2670485B1/fr
Priority to US13/983,487 priority patent/US9186525B2/en
Publication of WO2012104416A1 publication Critical patent/WO2012104416A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1048—Monitoring, verifying, controlling systems and methods
    • A61N5/1071—Monitoring, verifying, controlling systems and methods for verifying the dose delivered by the treatment plan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1048—Monitoring, verifying, controlling systems and methods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1048—Monitoring, verifying, controlling systems and methods
    • A61N5/1075—Monitoring, verifying, controlling systems and methods for testing, calibrating, or quality assurance of the radiation treatment apparatus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01T—MEASUREMENT OF NUCLEAR OR X-RADIATION
    • G01T1/00—Measuring X-radiation, gamma radiation, corpuscular radiation, or cosmic radiation
    • G01T1/29—Measurement performed on radiation beams, e.g. position or section of the beam; Measurement of spatial distribution of radiation
    • G01T1/2914—Measurement of spatial distribution of radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1048—Monitoring, verifying, controlling systems and methods
    • A61N5/1049—Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam
    • A61N2005/1052—Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam using positron emission tomography [PET] single photon emission computer tomography [SPECT] imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N2005/1085—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy characterised by the type of particles applied to the patient
    • A61N2005/1087—Ions; Protons
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04C—ROTARY-PISTON, OR OSCILLATING-PISTON, POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; ROTARY-PISTON, OR OSCILLATING-PISTON, POSITIVE-DISPLACEMENT PUMPS
    • F04C2270/00—Control; Monitoring or safety arrangements
    • F04C2270/04—Force
    • F04C2270/041—Controlled or regulated

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pathology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Molecular Biology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Measurement Of Radiation (AREA)

Abstract

L'invention porte sur un appareil et un procédé de vérification de thérapie par hadrons chargés par détection et/ou quantification de gammas instantanés produits lors de l'irradiation d'une cible (6) par un faisceau de hadrons chargés. L'appareil comprend un collimateur (1) comportant une partie en forme de fente (2) configurée pour être agencée perpendiculairement à la ligne de faisceau et tournée vers la cible, un moyen de détection (3, 4) approprié pour détecter lesdits gammas instantanés et un moyen de calcul et de représentation. Dans l'appareil et le procédé de l'invention, la fente est configurée pour permettre le passage de gammas instantanés émis à partir d'une plage de profondeurs dans ladite cible (6), lesdites profondeurs étant mesurées dans la direction du faisceau de hadrons chargés. En outre, ledit moyen de détection est configuré pour détecter des gammas instantanés émis à partir de chaque emplacement à l'intérieur de ladite plage, et ledit moyen de calcul et de représentation est configuré pour déduire, à partir d'un gamma instantané détecté, une valeur représentative de la dose à l'emplacement à partir duquel ledit gamma instantané est émis, et représenter une distribution corrélée à la dose pour une pluralité d'emplacements à l'intérieur de ladite plage.
PCT/EP2012/051866 2011-02-04 2012-02-03 Appareil de vérification de thérapie par particules WO2012104416A1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP12702533.6A EP2670485B1 (fr) 2011-02-04 2012-02-03 Appareil de vérification de thérapie par particules
US13/983,487 US9186525B2 (en) 2011-02-04 2012-02-03 Apparatus for particle therapy verification

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP11153357 2011-02-04
EP11153357.6 2011-02-04

Publications (1)

Publication Number Publication Date
WO2012104416A1 true WO2012104416A1 (fr) 2012-08-09

Family

ID=43728786

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2012/051866 WO2012104416A1 (fr) 2011-02-04 2012-02-03 Appareil de vérification de thérapie par particules

Country Status (4)

Country Link
US (1) US9186525B2 (fr)
EP (2) EP2670485B1 (fr)
NO (1) NO2977083T3 (fr)
WO (1) WO2012104416A1 (fr)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102013102920A1 (de) 2013-03-21 2014-09-25 Technische Universität Dresden Vorrichtung zum Verifizieren der Hadronentherapie durch Messung prompter Gammastrahlung unter Verwendung aktiver Kollimatoren
DE102013218982A1 (de) * 2013-09-20 2015-03-26 Helmholtz-Zentrum Dresden - Rossendorf E.V. Verfahren und Einrichtung zur Kontrolle der Reichweite von Partikelstrahlung einer Bestrahlungseinrichtung zur Strahlentherapie
EP2942081A1 (fr) 2014-05-09 2015-11-11 Ion Beam Applications S.A. Appareil pour la vérification d'une thérapie particulaire comprenant un collimateur à multiples ouvertures
EP2950119A1 (fr) 2014-05-26 2015-12-02 Ion Beam Applications S.A. Système et procédé permettant de vérifier un faisceau de particules
WO2021009281A1 (fr) 2019-07-17 2021-01-21 Deutsches Krebsforschungszentrum Dispositif et méthode de surveillance d'un traitement d'une partie du corps d'un patient avec des particules
US11506801B2 (en) 2018-10-10 2022-11-22 Ebamed Sa Prompt gamma monitor for hadron therapy

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL2007596C2 (en) * 2011-10-14 2013-04-16 Univ Delft Tech A hadron radiation installation and verification method.
CN110237447B (zh) 2013-09-27 2021-11-02 梅维昂医疗系统股份有限公司 粒子治疗系统
US9962560B2 (en) 2013-12-20 2018-05-08 Mevion Medical Systems, Inc. Collimator and energy degrader
US10675487B2 (en) 2013-12-20 2020-06-09 Mevion Medical Systems, Inc. Energy degrader enabling high-speed energy switching
US9661736B2 (en) 2014-02-20 2017-05-23 Mevion Medical Systems, Inc. Scanning system for a particle therapy system
US10786689B2 (en) 2015-11-10 2020-09-29 Mevion Medical Systems, Inc. Adaptive aperture
EP3906968A1 (fr) 2016-07-08 2021-11-10 Mevion Medical Systems, Inc. Planification de traitement
EP3487403B1 (fr) * 2016-07-25 2023-11-01 Sarah Kathryn Patch Systèmes de vérification de la portée d'un faisceau de rayonnement au moyen de mesures soniques
EP3305200A1 (fr) 2016-10-07 2018-04-11 Ion Beam Applications S.A. Appareil médical comprenant un dispositif d'hadronthérapie, un irm et un système à rayonnement gamma instantané
EP3308834B1 (fr) 2016-10-11 2019-01-09 Ion Beam Applications Appareil de thérapie par particules comprenant un irm
US10695584B2 (en) 2016-12-06 2020-06-30 Electronics And Telecommunications Research Institute Method for measuring depth profile of particle beam using acoustic signals generated by the particle beam
US11103730B2 (en) 2017-02-23 2021-08-31 Mevion Medical Systems, Inc. Automated treatment in particle therapy
KR20180114455A (ko) 2017-04-10 2018-10-18 한국전자통신연구원 양성자 및 초음파를 이용한 치료 장치 및 이를 이용한 암 치료 방법
EP3645111A1 (fr) 2017-06-30 2020-05-06 Mevion Medical Systems, Inc. Collimateur configurable commandé au moyen de moteurs linéaires
WO2020185543A1 (fr) 2019-03-08 2020-09-17 Mevion Medical Systems, Inc. Collimateur et dégradeur d'énergie pour système de thérapie par particules
NO346536B1 (en) * 2019-04-10 2022-09-26 Bergen Teknologioverfoering As System for charged particle therapy verification

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080237476A1 (en) * 2007-03-30 2008-10-02 General Electric Company Adjustable pinhole collimators method and system
WO2010000857A1 (fr) * 2008-07-03 2010-01-07 Ion Beam Applications S.A. Dispositif et procédé pour la vérification d'une thérapie particulaire

Family Cites Families (3)

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Publication number Priority date Publication date Assignee Title
WO2008003527A1 (fr) * 2006-07-06 2008-01-10 Ion Beam Applications S.A. Procédé pour traiter un volume cible avec un faisceau de particules et dispositif pour sa réalisation
FR2930995B1 (fr) * 2008-05-07 2010-07-30 Centre Nat Rech Scient Procede et dispositif de mesure en temps reel d'une dose locale lors du bombardement d'une cible par des hadrons au moyen des gamma prompts
WO2012161852A2 (fr) * 2011-03-07 2012-11-29 Loma Linda University Medical Center Systèmes, dispositifs et procédés relatifs à l'étalonnage d'un scanner de tomographie par émission de protons calculée par ordinateur

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080237476A1 (en) * 2007-03-30 2008-10-02 General Electric Company Adjustable pinhole collimators method and system
WO2010000857A1 (fr) * 2008-07-03 2010-01-07 Ion Beam Applications S.A. Dispositif et procédé pour la vérification d'une thérapie particulaire

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
MIN CHUL HEE ET AL: "Development of an Array-Type Prompt Gamma Detection System for the Online Measurement of the Range of the Proton Beam in a Patient: a Monte Carlo Feasibility Study", JOURNAL OF THE KOREAN PHYSICAL SOCIETY, SEOUL, KR, vol. 52, no. 3, 15 March 2008 (2008-03-15), pages 888 - 891, XP002509601, ISSN: 0374-4884 *

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102013102920A1 (de) 2013-03-21 2014-09-25 Technische Universität Dresden Vorrichtung zum Verifizieren der Hadronentherapie durch Messung prompter Gammastrahlung unter Verwendung aktiver Kollimatoren
DE102013218982A1 (de) * 2013-09-20 2015-03-26 Helmholtz-Zentrum Dresden - Rossendorf E.V. Verfahren und Einrichtung zur Kontrolle der Reichweite von Partikelstrahlung einer Bestrahlungseinrichtung zur Strahlentherapie
EP2942081A1 (fr) 2014-05-09 2015-11-11 Ion Beam Applications S.A. Appareil pour la vérification d'une thérapie particulaire comprenant un collimateur à multiples ouvertures
US9802061B2 (en) 2014-05-09 2017-10-31 Ion Beam Applications S.A. Apparatus for particle therapy verification comprising a collimator with multiple openings
EP2950119A1 (fr) 2014-05-26 2015-12-02 Ion Beam Applications S.A. Système et procédé permettant de vérifier un faisceau de particules
US11506801B2 (en) 2018-10-10 2022-11-22 Ebamed Sa Prompt gamma monitor for hadron therapy
WO2021009281A1 (fr) 2019-07-17 2021-01-21 Deutsches Krebsforschungszentrum Dispositif et méthode de surveillance d'un traitement d'une partie du corps d'un patient avec des particules

Also Published As

Publication number Publication date
EP2670485A1 (fr) 2013-12-11
US9186525B2 (en) 2015-11-17
NO2977083T3 (fr) 2018-05-26
EP2670485B1 (fr) 2015-09-02
EP2977083B1 (fr) 2017-12-27
EP2977083A1 (fr) 2016-01-27
US20140061493A1 (en) 2014-03-06

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