WO2012082952A3 - Percutaneously deliverable heart valve including folded membrane cusps with integral leaflets - Google Patents

Percutaneously deliverable heart valve including folded membrane cusps with integral leaflets Download PDF

Info

Publication number
WO2012082952A3
WO2012082952A3 PCT/US2011/064989 US2011064989W WO2012082952A3 WO 2012082952 A3 WO2012082952 A3 WO 2012082952A3 US 2011064989 W US2011064989 W US 2011064989W WO 2012082952 A3 WO2012082952 A3 WO 2012082952A3
Authority
WO
WIPO (PCT)
Prior art keywords
heart valve
lattice frame
cusps
conical shape
valve including
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2011/064989
Other languages
French (fr)
Other versions
WO2012082952A2 (en
Inventor
David R. Fish
Eduardo Induni
David Paniagua
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Colibri Heart Valve LLC
Original Assignee
Colibri Heart Valve LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46245357&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=WO2012082952(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority to JP2013544758A priority Critical patent/JP2014507179A/en
Priority to CA2820738A priority patent/CA2820738C/en
Priority to AU2011343755A priority patent/AU2011343755A1/en
Priority to EP11848038.3A priority patent/EP2651337B8/en
Priority to CN201180067413.6A priority patent/CN103391756B/en
Application filed by Colibri Heart Valve LLC filed Critical Colibri Heart Valve LLC
Priority to SG2013043369A priority patent/SG191008A1/en
Publication of WO2012082952A2 publication Critical patent/WO2012082952A2/en
Publication of WO2012082952A3 publication Critical patent/WO2012082952A3/en
Anticipated expiration legal-status Critical
Priority to AU2017200883A priority patent/AU2017200883B2/en
Priority to AU2019204445A priority patent/AU2019204445A1/en
Ceased legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/24Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2412Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with soft flexible valve members, e.g. tissue valves shaped like natural valves
    • A61F2/2415Manufacturing methods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/24Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2412Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with soft flexible valve members, e.g. tissue valves shaped like natural valves
    • A61F2/2418Scaffolds therefor, e.g. support stents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2220/00Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2220/0025Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
    • A61F2220/0075Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements sutured, ligatured or stitched, retained or tied with a rope, string, thread, wire or cable
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0002Two-dimensional shapes, e.g. cross-sections
    • A61F2230/0028Shapes in the form of latin or greek characters
    • A61F2230/0054V-shaped
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0063Three-dimensional shapes
    • A61F2230/0067Three-dimensional shapes conical

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Manufacturing & Machinery (AREA)
  • Prostheses (AREA)

Abstract

A transcatheter, percutaneously implantable, prosthetic heart valve is provided that comprises a lattice frame and two or more integrated cusp and leaflet folded structures attached to the lattice frame. The two or more integrated cusp and leaflet folded structures each comprise a flat sheet of biocompatible membrane that is folded to include a substantially conical shape according to a flat folding pattern. The substantially conical shape is further formed by joining apposing sides of the substantially conical shape along a seam. The two or more integrated cusp and leaflet folded structures are each attached along their respective seams to the lattice frame in a direction substantially parallel to an axis of the lattice frame. Embodiments of valves described herein have application within the entire vascular system.
PCT/US2011/064989 2010-12-14 2011-12-14 Percutaneously deliverable heart valve including folded membrane cusps with integral leaflets Ceased WO2012082952A2 (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
SG2013043369A SG191008A1 (en) 2010-12-14 2011-12-14 Percutaneously deliverable heart valve including folded membrane cusps with integral leaflets
CA2820738A CA2820738C (en) 2010-12-14 2011-12-14 Percutaneously deliverable heart valve including folded membrane cusps with integral leaflets
AU2011343755A AU2011343755A1 (en) 2010-12-14 2011-12-14 Percutaneously deliverable heart valve including folded membrane cusps with integral leaflets
EP11848038.3A EP2651337B8 (en) 2010-12-14 2011-12-14 Percutaneously deliverable heart valve including folded membrane cusps with integral leaflets
CN201180067413.6A CN103391756B (en) 2010-12-14 2011-12-14 Including have integrate leaflet folded membrane cusp can percutaneous conveying cardiac valve
JP2013544758A JP2014507179A (en) 2010-12-14 2011-12-14 Percutaneously deliverable heart valve including folded membrane cusps with integrated leaflets
AU2017200883A AU2017200883B2 (en) 2010-12-14 2017-02-09 Percutaneously deliverable heart valve including folded membrane cusps with integral leaflets
AU2019204445A AU2019204445A1 (en) 2010-12-14 2019-06-25 Percutaneously deliverable heart valve including folded membrane cusps with integral leaflets

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US42305110P 2010-12-14 2010-12-14
US61/423,051 2010-12-14
US13/326,196 US9737400B2 (en) 2010-12-14 2011-12-14 Percutaneously deliverable heart valve including folded membrane cusps with integral leaflets
US13/326,196 2011-12-14

Publications (2)

Publication Number Publication Date
WO2012082952A2 WO2012082952A2 (en) 2012-06-21
WO2012082952A3 true WO2012082952A3 (en) 2012-09-07

Family

ID=46245357

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2011/064989 Ceased WO2012082952A2 (en) 2010-12-14 2011-12-14 Percutaneously deliverable heart valve including folded membrane cusps with integral leaflets

Country Status (7)

Country Link
US (3) US9737400B2 (en)
JP (3) JP2014507179A (en)
CN (1) CN103391756B (en)
AU (1) AU2011343755A1 (en)
CA (2) CA2820738C (en)
SG (2) SG191008A1 (en)
WO (1) WO2012082952A2 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8900294B2 (en) 2002-01-04 2014-12-02 Colibri Heart Valve Llc Method of controlled release of a percutaneous replacement heart valve
US9119738B2 (en) 2010-06-28 2015-09-01 Colibri Heart Valve Llc Method and apparatus for the endoluminal delivery of intravascular devices

Families Citing this family (121)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005003632A1 (en) 2005-01-20 2006-08-17 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Catheter for the transvascular implantation of heart valve prostheses
ATE515244T1 (en) * 2007-02-15 2011-07-15 Cook Inc ARTIFICIAL VALVE PROSTHESIS WITH FREE LEAF SECTION
US7896915B2 (en) 2007-04-13 2011-03-01 Jenavalve Technology, Inc. Medical device for treating a heart valve insufficiency
US9101691B2 (en) 2007-06-11 2015-08-11 Edwards Lifesciences Corporation Methods for pre-stressing and capping bioprosthetic tissue
US8357387B2 (en) 2007-12-21 2013-01-22 Edwards Lifesciences Corporation Capping bioprosthetic tissue to reduce calcification
US9044318B2 (en) 2008-02-26 2015-06-02 Jenavalve Technology Gmbh Stent for the positioning and anchoring of a valvular prosthesis
WO2011104269A1 (en) 2008-02-26 2011-09-01 Jenavalve Technology Inc. Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient
AU2010236288A1 (en) 2009-04-15 2011-10-20 Cardiaq Valve Technologies, Inc. Vascular implant and delivery system
US10856978B2 (en) 2010-05-20 2020-12-08 Jenavalve Technology, Inc. Catheter system
CN103002833B (en) 2010-05-25 2016-05-11 耶拿阀门科技公司 Artificial heart valve and comprise artificial heart valve and support through conduit carry interior prosthese
PL3593762T3 (en) 2010-10-05 2021-05-04 Edwards Lifesciences Corporation HEART RESTRAINT AND DEVICE FOR INSERTION
SG191008A1 (en) 2010-12-14 2013-07-31 Colibri Heart Valve Llc Percutaneously deliverable heart valve including folded membrane cusps with integral leaflets
CA2852369A1 (en) 2011-10-21 2013-04-25 Jenavalve Technology Inc. Catheter system for introducing an expandable heart valve stent into the body of a patient, insertion system with a catheter system and medical device for treatment of a heart valve defect
WO2013067194A2 (en) * 2011-11-01 2013-05-10 Stinis Curtiss T Aortic valve positioning systems, devices, and methods
US9878127B2 (en) 2012-05-16 2018-01-30 Jenavalve Technology, Inc. Catheter delivery system for heart valve prosthesis
US9554902B2 (en) 2012-06-28 2017-01-31 St. Jude Medical, Cardiology Division, Inc. Leaflet in configuration for function in various shapes and sizes
US20140005776A1 (en) 2012-06-29 2014-01-02 St. Jude Medical, Cardiology Division, Inc. Leaflet attachment for function in various shapes and sizes
US9615920B2 (en) 2012-06-29 2017-04-11 St. Jude Medical, Cardiology Divisions, Inc. Commissure attachment feature for prosthetic heart valve
ES2690824T3 (en) 2012-07-02 2018-11-22 Boston Scientific Scimed, Inc. Formation of cardiac valve prosthesis
US9283072B2 (en) 2012-07-25 2016-03-15 W. L. Gore & Associates, Inc. Everting transcatheter valve and methods
US10376360B2 (en) 2012-07-27 2019-08-13 W. L. Gore & Associates, Inc. Multi-frame prosthetic valve apparatus and methods
US9398952B2 (en) * 2012-12-19 2016-07-26 W. L. Gore & Associates, Inc. Planar zone in prosthetic heart valve leaflet
US10321986B2 (en) * 2012-12-19 2019-06-18 W. L. Gore & Associates, Inc. Multi-frame prosthetic heart valve
US9144492B2 (en) * 2012-12-19 2015-09-29 W. L. Gore & Associates, Inc. Truncated leaflet for prosthetic heart valves, preformed valve
US9968443B2 (en) * 2012-12-19 2018-05-15 W. L. Gore & Associates, Inc. Vertical coaptation zone in a planar portion of prosthetic heart valve leaflet
US10039638B2 (en) 2012-12-19 2018-08-07 W. L. Gore & Associates, Inc. Geometric prosthetic heart valves
US10966820B2 (en) * 2012-12-19 2021-04-06 W. L. Gore & Associates, Inc. Geometric control of bending character in prosthetic heart valve leaflets
US9101469B2 (en) 2012-12-19 2015-08-11 W. L. Gore & Associates, Inc. Prosthetic heart valve with leaflet shelving
US9737398B2 (en) * 2012-12-19 2017-08-22 W. L. Gore & Associates, Inc. Prosthetic valves, frames and leaflets and methods thereof
AU2014214700B2 (en) * 2013-02-11 2018-01-18 Cook Medical Technologies Llc Expandable support frame and medical device
US9681951B2 (en) 2013-03-14 2017-06-20 Edwards Lifesciences Cardiaq Llc Prosthesis with outer skirt and anchors
WO2014203106A1 (en) * 2013-06-21 2014-12-24 Jenavalve Technology Gmbh Collapsible prosthetic heart valve
WO2015028209A1 (en) 2013-08-30 2015-03-05 Jenavalve Technology Gmbh Radially collapsible frame for a prosthetic valve and method for manufacturing such a frame
US9615922B2 (en) 2013-09-30 2017-04-11 Edwards Lifesciences Corporation Method and apparatus for preparing a contoured biological tissue
US10959839B2 (en) 2013-10-08 2021-03-30 Edwards Lifesciences Corporation Method for directing cellular migration patterns on a biological tissue
EP3073964B1 (en) 2013-11-27 2024-12-18 St. Jude Medical, Cardiology Division, Inc. Cuff stitching reinforcement
CN106659567B (en) 2014-08-18 2019-06-14 W.L.戈尔及同仁股份有限公司 Frame with integral suture cuff for prosthetic valve
US9827094B2 (en) 2014-09-15 2017-11-28 W. L. Gore & Associates, Inc. Prosthetic heart valve with retention elements
US10507101B2 (en) * 2014-10-13 2019-12-17 W. L. Gore & Associates, Inc. Valved conduit
US9839512B2 (en) * 2015-02-03 2017-12-12 Boston Scientific, Inc. Prosthetic heart valve having notched leaflet
WO2016150806A1 (en) 2015-03-20 2016-09-29 Jenavalve Technology, Inc. Heart valve prosthesis delivery system and method for delivery of heart valve prosthesis with introducer sheath
US10299915B2 (en) * 2015-04-09 2019-05-28 Boston Scientific Scimed, Inc. Synthetic heart valves composed of zwitterionic polymers
US10314696B2 (en) 2015-04-09 2019-06-11 Boston Scientific Scimed, Inc. Prosthetic heart valves having fiber reinforced leaflets
US10426609B2 (en) 2015-04-09 2019-10-01 Boston Scientific Scimed, Inc. Fiber reinforced prosthetic heart valve having undulating fibers
CN107530168B (en) 2015-05-01 2020-06-09 耶拿阀门科技股份有限公司 Device and method with reduced pacemaker ratio in heart valve replacement
US10716671B2 (en) 2015-07-02 2020-07-21 Boston Scientific Scimed, Inc. Prosthetic heart valve composed of composite fibers
US10413403B2 (en) 2015-07-14 2019-09-17 Boston Scientific Scimed, Inc. Prosthetic heart valve including self-reinforced composite leaflets
CN109475419B (en) 2016-05-13 2021-11-09 耶拿阀门科技股份有限公司 Heart valve prosthesis delivery systems and methods for delivering heart valve prostheses through guide sheaths and loading systems
US10368982B2 (en) 2016-05-19 2019-08-06 Boston Scientific Scimed, Inc. Prosthetic valves, valve leaflets and related methods
US11096781B2 (en) * 2016-08-01 2021-08-24 Edwards Lifesciences Corporation Prosthetic heart valve
US10653523B2 (en) 2017-01-19 2020-05-19 4C Medical Technologies, Inc. Systems, methods and devices for delivery systems, methods and devices for implanting prosthetic heart valves
US10561495B2 (en) 2017-01-24 2020-02-18 4C Medical Technologies, Inc. Systems, methods and devices for two-step delivery and implantation of prosthetic heart valve
CN110392557A (en) 2017-01-27 2019-10-29 耶拿阀门科技股份有限公司 Heart valve simulation
US12029647B2 (en) 2017-03-07 2024-07-09 4C Medical Technologies, Inc. Systems, methods and devices for prosthetic heart valve with single valve leaflet
PL3606467T3 (en) * 2017-04-06 2023-12-11 Regents Of The University Of Minnesota Prosthetic valves and methods of making
CN110494170A (en) 2017-04-25 2019-11-22 波士顿科学国际有限公司 Biocompatibility polyisobutene-fibrous composite and method
EP3631062B1 (en) 2017-05-31 2025-08-27 Edwards Lifesciences Corporation Collagen fibers and articles formed therefrom
US12036113B2 (en) 2017-06-14 2024-07-16 4C Medical Technologies, Inc. Delivery of heart chamber prosthetic valve implant
EP3668451A1 (en) 2017-08-17 2020-06-24 Incubar LLC Prosthetic vascular valve and methods associated therewith
IL254099B (en) 2017-08-22 2021-02-28 Geonovation Medical Tech Ltd Foldable one-way valve prosthesis
WO2019051476A1 (en) 2017-09-11 2019-03-14 Incubar, LLC Conduit vascular implant sealing device for reducing endoleak
CN111182856B (en) 2017-09-12 2022-04-29 W.L.戈尔及同仁股份有限公司 Leaflet Frame Attachments for Prosthetic Valves
CN111163728B (en) 2017-09-27 2022-04-29 W.L.戈尔及同仁股份有限公司 Prosthetic valve with mechanically coupled leaflets
CN111132636B (en) 2017-09-27 2022-04-08 W.L.戈尔及同仁股份有限公司 Prosthetic valves with expandable frames and associated systems and methods
US11090153B2 (en) 2017-10-13 2021-08-17 W. L. Gore & Associates, Inc. Telescoping prosthetic valve and delivery system
KR102609690B1 (en) 2017-10-19 2023-12-05 안테리스 테크놀로지스 코퍼레이션 Replacement heart valve with reduced sutures
EP3703615B1 (en) 2017-10-31 2024-05-15 W. L. Gore & Associates, Inc. Transcatheter deployment systems and associated methods
US11439502B2 (en) 2017-10-31 2022-09-13 W. L. Gore & Associates, Inc. Medical valve and leaflet promoting tissue ingrowth
US11154397B2 (en) 2017-10-31 2021-10-26 W. L. Gore & Associates, Inc. Jacket for surgical heart valve
US11123183B2 (en) 2017-10-31 2021-09-21 W. L. Gore & Associates, Inc. Prosthetic heart valve
US20190201192A1 (en) * 2018-01-02 2019-07-04 4C Medical Technologies, Inc. Stent features and methods to aid with apposition and alignment to native anatomy, mitigation of paravalvular leak and functional efficiency of prosthetic heart valve
CA3081049A1 (en) 2018-01-23 2019-08-01 Edwards Lifesciences Corporation Method for pre-stretching implantable biocompatible materials, and materials and devices produced thereby
EP3720390B1 (en) 2018-01-25 2024-05-01 Edwards Lifesciences Corporation Delivery system for aided replacement valve recapture and repositioning post- deployment
WO2019195860A2 (en) 2018-04-04 2019-10-10 Vdyne, Llc Devices and methods for anchoring transcatheter heart valve
PL238191B1 (en) * 2018-07-24 2021-07-19 American Heart Of Poland Spolka Akcyjna Low-profile, balloon-expanded artificial heart valve, especially aortic, percutaneously implanted
PL238190B1 (en) * 2018-07-24 2021-07-19 American Heart Of Poland Spolka Akcyjna Biological, low-profile, balloon-expanded heart valve, especially aortic, percutaneously implanted, and method of its manufacture
US11857441B2 (en) 2018-09-04 2024-01-02 4C Medical Technologies, Inc. Stent loading device
US10321995B1 (en) 2018-09-20 2019-06-18 Vdyne, Llc Orthogonally delivered transcatheter heart valve replacement
US12186187B2 (en) 2018-09-20 2025-01-07 Vdyne, Inc. Transcatheter deliverable prosthetic heart valves and methods of delivery
US11071627B2 (en) 2018-10-18 2021-07-27 Vdyne, Inc. Orthogonally delivered transcatheter heart valve frame for valve in valve prosthesis
US11344413B2 (en) 2018-09-20 2022-05-31 Vdyne, Inc. Transcatheter deliverable prosthetic heart valves and methods of delivery
US11278437B2 (en) 2018-12-08 2022-03-22 Vdyne, Inc. Compression capable annular frames for side delivery of transcatheter heart valve replacement
US10595994B1 (en) 2018-09-20 2020-03-24 Vdyne, Llc Side-delivered transcatheter heart valve replacement
US11109969B2 (en) 2018-10-22 2021-09-07 Vdyne, Inc. Guidewire delivery of transcatheter heart valve
WO2020092205A1 (en) 2018-11-01 2020-05-07 Edwards Lifesciences Corporation Transcatheter pulmonic regenerative valve
USD926322S1 (en) 2018-11-07 2021-07-27 W. L. Gore & Associates, Inc. Heart valve cover
US11253359B2 (en) 2018-12-20 2022-02-22 Vdyne, Inc. Proximal tab for side-delivered transcatheter heart valves and methods of delivery
WO2020146842A1 (en) 2019-01-10 2020-07-16 Vdyne, Llc Anchor hook for side-delivery transcatheter heart valve prosthesis
US11185409B2 (en) 2019-01-26 2021-11-30 Vdyne, Inc. Collapsible inner flow control component for side-delivered transcatheter heart valve prosthesis
US11273032B2 (en) 2019-01-26 2022-03-15 Vdyne, Inc. Collapsible inner flow control component for side-deliverable transcatheter heart valve prosthesis
US12544226B2 (en) 2019-02-14 2026-02-10 4C Medical Technologies, Inc. Hydrophilic skirt for paravalvular leak mitigation and fit and apposition optimization for prosthetic heart valve implants
US11497601B2 (en) 2019-03-01 2022-11-15 W. L. Gore & Associates, Inc. Telescoping prosthetic valve with retention element
EP4729034A2 (en) 2019-03-05 2026-04-22 VDyne, Inc. Tricuspid regurgitation control devices for orthogonal transcatheter heart valve prosthesis
US11076956B2 (en) 2019-03-14 2021-08-03 Vdyne, Inc. Proximal, distal, and anterior anchoring tabs for side-delivered transcatheter mitral valve prosthesis
US11173027B2 (en) 2019-03-14 2021-11-16 Vdyne, Inc. Side-deliverable transcatheter prosthetic valves and methods for delivering and anchoring the same
CN113873973B (en) * 2019-03-26 2023-12-22 爱德华兹生命科学公司 prosthetic heart valve
JP7381601B2 (en) 2019-04-12 2023-11-15 エドワーズ ライフサイエンシーズ コーポレイション Valves with multi-part frames and associated resilient bridge features
US11452628B2 (en) 2019-04-15 2022-09-27 4C Medical Technologies, Inc. Loading systems for collapsible prosthetic heart valve devices and methods thereof
CN114072106B (en) 2019-05-04 2025-09-19 维迪内股份有限公司 Lacing devices and methods for deploying a side-delivered prosthetic heart valve in a native annulus
US11406494B2 (en) * 2019-07-29 2022-08-09 Shinka MIYAMOTO Prosthetic valve forming template and prosthetic valve
CN121101808A (en) 2019-08-20 2025-12-12 维迪内股份有限公司 Devices and methods for the delivery and retrieval of transcatheter artificial valves that can be delivered laterally.
EP4021445B8 (en) 2019-08-26 2025-12-10 VDyne, Inc. Side-deliverable transcatheter prosthetic valves
CN114364340B (en) * 2019-08-29 2026-01-09 爱德华兹生命科学公司 artificial heart valve
US12245935B2 (en) 2019-11-26 2025-03-11 Boston Scientific Limited Composite web-polymer heart valve
AU2020399770B2 (en) 2019-12-09 2026-03-12 Edwards Lifesciences Corporation Bioprosthetic tissue preparation
US11234813B2 (en) 2020-01-17 2022-02-01 Vdyne, Inc. Ventricular stability elements for side-deliverable prosthetic heart valves and methods of delivery
US11931253B2 (en) 2020-01-31 2024-03-19 4C Medical Technologies, Inc. Prosthetic heart valve delivery system: ball-slide attachment
US12133797B2 (en) 2020-01-31 2024-11-05 4C Medical Technologies, Inc. Prosthetic heart valve delivery system: paddle attachment feature
EP4114308A1 (en) * 2020-03-02 2023-01-11 Biotronik AG Heart valve prosthesis
US12053375B2 (en) 2020-03-05 2024-08-06 4C Medical Technologies, Inc. Prosthetic mitral valve with improved atrial and/or annular apposition and paravalvular leakage mitigation
US11992403B2 (en) 2020-03-06 2024-05-28 4C Medical Technologies, Inc. Devices, systems and methods for improving recapture of prosthetic heart valve device with stent frame having valve support with inwardly stent cells
US20230157817A1 (en) * 2020-04-01 2023-05-25 Nininger Medical, Inc. Three-dimensional thin-film leaflet valve device
CN113712704A (en) * 2020-04-17 2021-11-30 山前(珠海)生物材料科技有限公司 Heart valve prosthesis, artificial valve formed by same and preparation method
US20240033077A1 (en) * 2020-10-01 2024-02-01 The Medical College Of Wisconsin, Inc. Foldable Prosthetic Heart Valve
EP4243734A1 (en) * 2020-11-12 2023-09-20 Edwards Lifesciences Corporation Prosthetic heart valve leaflet assemblies and methods
CN113476181B (en) * 2021-08-19 2022-04-26 苏州茵络医疗器械有限公司 Mitral valve repair support
WO2023220254A1 (en) * 2022-05-11 2023-11-16 Envveno Medical Corporation Transcatheter valve for venous insufficiency
US12594164B1 (en) 2022-09-01 2026-04-07 4C Medical Technologies, Inc. Prosthetic heart valve for natural blood flow
JP2025534210A (en) 2022-10-14 2025-10-15 ブイダイン,インコーポレイテッド Devices and methods for delivering prosthetic heart valves using supranuclear support
CN120152682A (en) 2022-11-09 2025-06-13 耶拿阀门科技公司 Catheter system for sequential deployment of expandable implants
US20240366366A1 (en) 2023-03-24 2024-11-07 4C Medical Technologies, Inc. Implant delivery

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5509930A (en) * 1993-12-17 1996-04-23 Autogenics Stentless heart valve
US20070043431A1 (en) * 2005-08-19 2007-02-22 Cook Incorporated Prosthetic valve
US20090112309A1 (en) * 2005-07-21 2009-04-30 The Florida International University Board Of Trustees Collapsible Heart Valve with Polymer Leaflets
US20100185277A1 (en) * 2007-09-26 2010-07-22 St. Jude Medical, Inc. Collapsible prosthetic heart valves
WO2011109450A2 (en) * 2010-03-01 2011-09-09 Colibri Heart Valve Llc Percutaneously deliverable heart valve and methods associated therewith

Family Cites Families (465)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3053938A (en) 1955-04-05 1962-09-11 Siemens Ag Electromagnetically actuating relays in coordinate switches
US3014024A (en) 1958-03-19 1961-12-19 Johnson & Johnson Collagen film
US3105492A (en) 1958-10-01 1963-10-01 Us Catheter & Instr Corp Synthetic blood vessel grafts
US3029819A (en) 1959-07-30 1962-04-17 J L Mcatee Artery graft and method of producing artery grafts
US3029671A (en) 1959-12-07 1962-04-17 Clifford Jack Method and apparatus for the repair of tubeless tires
US3045576A (en) 1960-05-24 1962-07-24 Mc Graw Edison Co Air directing louver device
US3320972A (en) 1964-04-16 1967-05-23 Roy F High Prosthetic tricuspid valve and method of and device for fabricating same
US3409914A (en) 1966-07-01 1968-11-12 Avco Corp Connector for blood pumps and the like
AT261800B (en) 1966-08-22 1968-05-10 Braun Internat Gmbh B Process for the manufacture of tubular, smooth or threaded tissue-blood vessel prostheses
US3548417A (en) 1967-09-05 1970-12-22 Ronnie G Kischer Heart valve having a flexible wall which rotates between open and closed positions
US3588920A (en) 1969-09-05 1971-06-29 Sigmund A Wesolowski Surgical vascular prostheses formed of polyester fiber paper
US3671979A (en) 1969-09-23 1972-06-27 Univ Utah Catheter mounted artificial heart valve for implanting in close proximity to a defective natural heart valve
US3878565A (en) 1971-07-14 1975-04-22 Providence Hospital Vascular prosthesis with external pile surface
US3709175A (en) 1971-07-26 1973-01-09 Cutter Lab Fabricating equipment for tissue type heart valve
US3945052A (en) 1972-05-01 1976-03-23 Meadox Medicals, Inc. Synthetic vascular graft and method for manufacturing the same
US4291420A (en) 1973-11-09 1981-09-29 Medac Gesellschaft Fur Klinische Spezialpraparate Mbh Artificial heart valve
US3986828A (en) 1974-03-05 1976-10-19 Meadox Medicals, Inc. Polymer fabric compacting process
GB1485908A (en) 1974-05-21 1977-09-14 Nath G Apparatus for applying light radiation
US3966401A (en) 1974-07-01 1976-06-29 Hancock Laboratories Incorporated Preparing natural tissue for implantation so as to provide improved flexibility
US3983581A (en) 1975-01-20 1976-10-05 William W. Angell Heart valve stent
FR2306671A1 (en) 1975-04-11 1976-11-05 Rhone Poulenc Ind VALVULAR IMPLANT
US4011947A (en) 1975-05-22 1977-03-15 Philip Nicholas Sawyer Packaged prosthetic device
US4060081A (en) 1975-07-15 1977-11-29 Massachusetts Institute Of Technology Multilayer membrane useful as synthetic skin
US4035849A (en) 1975-11-17 1977-07-19 William W. Angell Heart valve stent and process for preparing a stented heart valve prosthesis
CA1069652A (en) 1976-01-09 1980-01-15 Alain F. Carpentier Supported bioprosthetic heart valve with compliant orifice ring
US4084268A (en) 1976-04-22 1978-04-18 Shiley Laboratories, Incorporated Prosthetic tissue heart valve
US4082507A (en) 1976-05-10 1978-04-04 Sawyer Philip Nicholas Prosthesis and method for making the same
US4491986A (en) 1976-05-12 1985-01-08 Shlomo Gabbay Heart valve
US4056854A (en) 1976-09-28 1977-11-08 The United States Of America As Represented By The Department Of Health, Education And Welfare Aortic heart valve catheter
DK229077A (en) 1977-05-25 1978-11-26 Biocoating Aps HEARTBALL PROSTHET AND PROCEDURE FOR MANUFACTURING IT
US4164045A (en) 1977-08-03 1979-08-14 Carbomedics, Inc. Artificial vascular and patch grafts
US4172295A (en) 1978-01-27 1979-10-30 Shiley Scientific, Inc. Tri-cuspid three-tissue prosthetic heart valve
US4222126A (en) 1978-12-14 1980-09-16 The United States Of America As Represented By The Secretary Of The Department Of Health, Education & Welfare Unitized three leaflet heart valve
US4265694A (en) 1978-12-14 1981-05-05 The United States Of America As Represented By The Department Of Health, Education And Welfare Method of making unitized three leaflet heart valve
US4275469A (en) 1979-12-13 1981-06-30 Shelhigh Inc. Prosthetic heart valve
US4340977A (en) 1980-09-19 1982-07-27 Brownlee Richard T Catenary mitral valve replacement
US4388735A (en) 1980-11-03 1983-06-21 Shiley Inc. Low profile prosthetic xenograft heart valve
DE3042860A1 (en) 1980-11-13 1982-06-09 Heyl & Co Chemisch-Pharmazeutische Fabrik, 1000 Berlin COLLAGEN PREPARATIONS, METHODS FOR THEIR PRODUCTION AND THEIR USE IN HUMAN AND VETERINE MEDICINE
IT1144379B (en) 1981-07-14 1986-10-29 Sorin Biomedica Spa CARDIAC VALVE PROSTHESIS
US4350492A (en) 1981-08-24 1982-09-21 Vascor, Inc. Method for preparing tissue heart valve
US4364127A (en) 1981-10-02 1982-12-21 Research Corporation Trileaflet type prosthetic heart valve
US7018407B1 (en) 1981-10-29 2006-03-28 Medtronic Valve holder for tricuspid heart valve
EP0084395B1 (en) 1982-01-20 1986-08-13 Martin Morris Black Artificial heart valves
GR77865B (en) 1982-03-25 1984-09-25 Coats Ltd J & P
US4473423A (en) 1982-05-03 1984-09-25 University Of Utah Artificial heart valve made by vacuum forming technique
US4456589A (en) 1982-07-08 1984-06-26 Genetic Laboratories, Inc. Preparation of animal tissues for surgical implantation in human recipients
US4517687A (en) 1982-09-15 1985-05-21 Meadox Medicals, Inc. Synthetic woven double-velour graft
US4477930A (en) 1982-09-28 1984-10-23 Mitral Medical International, Inc. Natural tissue heat valve and method of making same
US4801299A (en) 1983-06-10 1989-01-31 University Patents, Inc. Body implants of extracellular matrix and means and methods of making and using such implants
CA1232407A (en) 1983-06-23 1988-02-09 David K. Walker Bubble heart valve
US4631052A (en) 1984-01-03 1986-12-23 Intravascular Surgical Instruments, Inc. Method and apparatus for surgically removing remote deposits
CA1239122A (en) 1984-02-09 1988-07-12 Toshio Komatsu Package containing quality-retaining agent
US4627436A (en) 1984-03-01 1986-12-09 Innoventions Biomedical Inc. Angioplasty catheter and method for use thereof
IT1208326B (en) 1984-03-16 1989-06-12 Sorin Biomedica Spa CARDIAC VALVE PROSTHESIS PROVIDED WITH VALVES OF ORGANIC FABRIC
US5007896A (en) 1988-12-19 1991-04-16 Surgical Systems & Instruments, Inc. Rotary-catheter for atherectomy
US4979939A (en) 1984-05-14 1990-12-25 Surgical Systems & Instruments, Inc. Atherectomy system with a guide wire
US4883458A (en) 1987-02-24 1989-11-28 Surgical Systems & Instruments, Inc. Atherectomy system and method of using the same
US4553974A (en) 1984-08-14 1985-11-19 Mayo Foundation Treatment of collagenous tissue with glutaraldehyde and aminodiphosphonate calcification inhibitor
US4580568A (en) 1984-10-01 1986-04-08 Cook, Incorporated Percutaneous endovascular stent and method for insertion thereof
US4728328A (en) 1984-10-19 1988-03-01 Research Corporation Cuffed tubular organic prostheses
US4759758A (en) 1984-12-07 1988-07-26 Shlomo Gabbay Prosthetic heart valve
US4600533A (en) 1984-12-24 1986-07-15 Collagen Corporation Collagen membranes for medical use
CH672247A5 (en) 1986-03-06 1989-11-15 Mo Vysshee Tekhnicheskoe Uchil
CA1303298C (en) 1986-08-06 1992-06-16 Alain Carpentier Flexible cardiac valvular support prosthesis
US4798611A (en) 1986-10-14 1989-01-17 Hancock Jaffe Laboratories Enhancement of xenogeneic tissue
IT1202558B (en) 1987-02-17 1989-02-09 Alberto Arpesani INTERNAL PROSTHESIS FOR THE REPLACEMENT OF A PART OF THE HUMAN BODY PARTICULARLY IN THE VASCULAR OPERATIONS
US4743231A (en) 1987-07-06 1988-05-10 Pharmacia Nutech Drug administration needle unit
JP2529112B2 (en) 1987-08-31 1996-08-28 株式会社 高研 Biological valve
US4870966A (en) 1988-02-01 1989-10-03 American Cyanamid Company Bioabsorbable surgical device for treating nerve defects
US4976733A (en) 1988-02-03 1990-12-11 Biomedical Design, Inc. Prevention of prosthesis calcification
US4892539A (en) 1988-02-08 1990-01-09 D-R Medical Systems, Inc. Vascular graft
US5746775A (en) 1988-04-01 1998-05-05 The Board Of Regent6S Of The University Of Michigan Method of making calcification-resistant bioprosthetic tissue
US5032128A (en) 1988-07-07 1991-07-16 Medtronic, Inc. Heart valve prosthesis
US5006104A (en) 1988-11-07 1991-04-09 The Cleveland Clinic Foundation Heart pump having contractible guide mechanism for pusher plate
US5011488A (en) 1988-12-07 1991-04-30 Robert Ginsburg Thrombus extraction system
US5171273A (en) 1989-01-13 1992-12-15 University Of Medicine And Dentistry Of New Jersey Synthetic collagen orthopaedic structures such as grafts, tendons and other structures
US4966604A (en) 1989-01-23 1990-10-30 Interventional Technologies Inc. Expandable atherectomy cutter with flexibly bowed blades
US6004330A (en) 1989-08-16 1999-12-21 Medtronic, Inc. Device or apparatus for manipulating matter
US5047041A (en) 1989-08-22 1991-09-10 Samuels Peter B Surgical apparatus for the excision of vein valves in situ
US5413601A (en) 1990-03-26 1995-05-09 Keshelava; Viktor V. Tubular organ prosthesis
US5080660A (en) 1990-05-11 1992-01-14 Applied Urology, Inc. Electrosurgical electrode
US5411552A (en) 1990-05-18 1995-05-02 Andersen; Henning R. Valve prothesis for implantation in the body and a catheter for implanting such valve prothesis
DK124690D0 (en) 1990-05-18 1990-05-18 Henning Rud Andersen FAT PROTECTION FOR IMPLEMENTATION IN THE BODY FOR REPLACEMENT OF NATURAL FLEET AND CATS FOR USE IN IMPLEMENTING A SUCH FAT PROTECTION
US5360443A (en) 1990-06-11 1994-11-01 Barone Hector D Aortic graft for repairing an abdominal aortic aneurysm
US5578071A (en) 1990-06-11 1996-11-26 Parodi; Juan C. Aortic graft
IT9084979A1 (en) 1990-07-30 1992-01-30 Imad Sheiban PERCUTANEOUS TRANSLUMINAL CORONARY ANGIOPLASTIC CATHETER WITH TWO BALLOONS AT ITS DISTAL END ONE OF SMALL DIAMETER (1, 5MM. FOLLOWED BY ANOTHER BALLOON OF GREATER DIAMETER VARIABLE FROM 2, 5 TO 4 MM THE BALLOON THE SMALL BALLOON
US5549664A (en) 1990-07-31 1996-08-27 Ube Industries, Ltd. Artificial blood vessel
US5139515A (en) 1990-08-15 1992-08-18 Francis Robicsek Ascending aortic prosthesis
US5336616A (en) 1990-09-12 1994-08-09 Lifecell Corporation Method for processing and preserving collagen-based tissues for transplantation
US5052771A (en) 1990-12-21 1991-10-01 Eastman Kodak Company Integrated electro-optical scanner
US5163955A (en) 1991-01-24 1992-11-17 Autogenics Rapid assembly, concentric mating stent, tissue heart valve with enhanced clamping and tissue alignment
CA2101557A1 (en) 1991-02-14 1992-08-15 Roger Tu Pliable biological graft materials and their methods of manufacture
US5282847A (en) 1991-02-28 1994-02-01 Medtronic, Inc. Prosthetic vascular grafts with a pleated structure
US5295958A (en) 1991-04-04 1994-03-22 Shturman Cardiology Systems, Inc. Method and apparatus for in vivo heart valve decalcification
DE69231964T2 (en) 1991-05-16 2002-06-06 Mures Cardiovascular Research, Inc. HEART VALVE
IT1245750B (en) 1991-05-24 1994-10-14 Sorin Biomedica Emodialisi S R CARDIAC VALVE PROSTHESIS, PARTICULARLY FOR REPLACING THE AORTIC VALVE
US5374539A (en) 1991-06-17 1994-12-20 Nimni; Marcel E. Process for purifying collagen and generating bioprosthesis
US6029671A (en) 1991-07-16 2000-02-29 Heartport, Inc. System and methods for performing endovascular procedures
US5203328A (en) 1991-07-17 1993-04-20 Georgia Tech Research Corporation Apparatus and methods for quantitatively measuring molecular changes in the ocular lens
US5522879A (en) 1991-11-12 1996-06-04 Ethicon, Inc. Piezoelectric biomedical device
US5395349A (en) 1991-12-13 1995-03-07 Endovascular Technologies, Inc. Dual valve reinforced sheath and method
US5316023A (en) 1992-01-08 1994-05-31 Expandable Grafts Partnership Method for bilateral intra-aortic bypass
US5489297A (en) 1992-01-27 1996-02-06 Duran; Carlos M. G. Bioprosthetic heart valve with absorbable stent
US5383927A (en) 1992-05-07 1995-01-24 Intervascular Inc. Non-thromogenic vascular prosthesis
JP2660101B2 (en) 1992-05-08 1997-10-08 シュナイダー・(ユーエスエイ)・インコーポレーテッド Esophageal stent and delivery device
US5332402A (en) 1992-05-12 1994-07-26 Teitelbaum George P Percutaneously-inserted cardiac valve
US5261878A (en) 1992-05-19 1993-11-16 The Regents Of The University Of California Double balloon pediatric ductus arteriosus stent catheter and method of using the same
US5449384A (en) 1992-09-28 1995-09-12 Medtronic, Inc. Dynamic annulus heart valve employing preserved porcine valve leaflets
EP0596145B1 (en) 1992-10-31 1996-05-08 Schneider (Europe) Ag Disposition for implanting a self-expanding endoprothesis
US6283127B1 (en) 1992-12-03 2001-09-04 Wesley D. Sterman Devices and methods for intracardiac procedures
US7213601B2 (en) 1993-02-22 2007-05-08 Heartport, Inc Minimally-invasive devices and methods for treatment of congestive heart failure
US6125852A (en) 1993-02-22 2000-10-03 Heartport, Inc. Minimally-invasive devices and methods for treatment of congestive heart failure
US5972030A (en) 1993-02-22 1999-10-26 Heartport, Inc. Less-invasive devices and methods for treatment of cardiac valves
US20020029783A1 (en) 1993-02-22 2002-03-14 Stevens John H. Minimally-invasive devices and methods for treatment of congestive heart failure
US6010531A (en) 1993-02-22 2000-01-04 Heartport, Inc. Less-invasive devices and methods for cardiac valve surgery
DE69332644T2 (en) 1993-08-20 2003-09-25 Kanji Inoue IMPLANT AND METHOD FOR FOLDING IT UP
EP0676937B1 (en) 1993-09-30 2004-03-17 Endogad Research PTY Limited Intraluminal graft
US5480424A (en) 1993-11-01 1996-01-02 Cox; James L. Heart valve replacement using flexible tubes
US5713950A (en) 1993-11-01 1998-02-03 Cox; James L. Method of replacing heart valves using flexible tubes
DE4340072C2 (en) 1993-11-24 1996-05-15 Siemens Ag Device for examining tissue with light
US5476506A (en) 1994-02-08 1995-12-19 Ethicon, Inc. Bi-directional crimped graft
WO1995028899A1 (en) 1994-04-22 1995-11-02 Medtronic, Inc. Stented bioprosthetic heart valve
US5558875A (en) 1994-06-06 1996-09-24 Wang; Su Method of preparing collagenous tissue
US5683451A (en) 1994-06-08 1997-11-04 Cardiovascular Concepts, Inc. Apparatus and methods for deployment release of intraluminal prostheses
US5824041A (en) 1994-06-08 1998-10-20 Medtronic, Inc. Apparatus and methods for placement and repositioning of intraluminal prostheses
US5522881A (en) 1994-06-28 1996-06-04 Meadox Medicals, Inc. Implantable tubular prosthesis having integral cuffs
US5554184A (en) 1994-07-27 1996-09-10 Machiraju; Venkat R. Heart valve
US5931969A (en) 1994-07-29 1999-08-03 Baxter International Inc. Methods and apparatuses for treating biological tissue to mitigate calcification
CA2147547C (en) 1994-08-02 2006-12-19 Peter J. Schmitt Thinly woven flexible graft
DE4430485C1 (en) 1994-08-27 1996-03-07 Braun B Surgical Gmbh Textile vascular prosthesis, process for its manufacture and tools for its manufacture
US5549666A (en) 1994-09-02 1996-08-27 Baxter International Inc. Natural tissue valve prostheses having variably complaint leaflets
US5545215A (en) 1994-09-14 1996-08-13 Duran; Carlos G. External sigmoid valve complex frame and valved conduit supported by the same
US5632760A (en) 1994-10-20 1997-05-27 Cordis Corporation Balloon catheter for stent implantation
CA2163708C (en) 1994-12-07 2007-08-07 Cordis Corporation Integrated dual-function catheter system for balloon angioplasty and stent delivery
EP0813397A4 (en) 1995-03-10 1999-10-06 Cardiovascular Concepts Inc Tubular endoluminar prosthesis having oblique ends
US6124523A (en) 1995-03-10 2000-09-26 Impra, Inc. Encapsulated stent
BE1009278A3 (en) 1995-04-12 1997-01-07 Corvita Europ Guardian self-expandable medical device introduced in cavite body, and medical device with a stake as.
WO1996036297A1 (en) 1995-05-19 1996-11-21 Kanji Inoue Transplantation instrument, method of bending same and method of transplanting same
US5728152A (en) 1995-06-07 1998-03-17 St. Jude Medical, Inc. Bioresorbable heart valve support
AU6178496A (en) 1995-06-07 1996-12-30 Stentco, Inc. Device and method for delivering and deploying intraluminal devices
US5861028A (en) 1996-09-09 1999-01-19 Shelhigh Inc Natural tissue heart valve and stent prosthesis and method for making the same
GB2312485B (en) 1996-04-24 1999-10-20 Endre Bodnar Bioprosthetic conduits
US5855601A (en) 1996-06-21 1999-01-05 The Trustees Of Columbia University In The City Of New York Artificial heart valve and method and device for implanting the same
US6077295A (en) 1996-07-15 2000-06-20 Advanced Cardiovascular Systems, Inc. Self-expanding stent delivery system
US5725535A (en) 1996-09-20 1998-03-10 Hegde; Anant V. Multiple balloon stent delivery catheter and method
TW501934B (en) 1996-11-20 2002-09-11 Tapic Int Co Ltd Collagen material and process for making the same
US5782914A (en) 1996-11-29 1998-07-21 Bio-Vascular, Inc. Method for preparing heterogeneous tissue grafts
AU755439B2 (en) 1996-12-10 2002-12-12 Purdue Research Foundation Artificial vascular valves
JP4074666B2 (en) 1996-12-10 2008-04-09 クック バイオテック、インク. Tubular grafts from purified submucosa
WO1998025549A1 (en) 1996-12-10 1998-06-18 Purdue Research Foundation Artificial vascular valves
NL1004827C2 (en) 1996-12-18 1998-06-19 Surgical Innovations Vof Device for regulating blood circulation.
EP0850607A1 (en) 1996-12-31 1998-07-01 Cordis Corporation Valve prosthesis for implantation in body channels
US5961539A (en) 1997-01-17 1999-10-05 Segmed, Inc. Method and apparatus for sizing, stabilizing and/or reducing the circumference of an anatomical structure
GB9701479D0 (en) 1997-01-24 1997-03-12 Aortech Europ Ltd Heart valve
US5928281A (en) 1997-03-27 1999-07-27 Baxter International Inc. Tissue heart valves
US5961549A (en) 1997-04-03 1999-10-05 Baxter International Inc. Multi-leaflet bioprosthetic heart valve
ES2231980T3 (en) 1997-04-11 2005-05-16 Cryolife, Inc. DECELURIZATION OF A FABRIC.
US5957949A (en) 1997-05-01 1999-09-28 World Medical Manufacturing Corp. Percutaneous placement valve stent
US6162245A (en) 1997-05-07 2000-12-19 Iowa-India Investments Company Limited Stent valve and stent graft
US6245102B1 (en) 1997-05-07 2001-06-12 Iowa-India Investments Company Ltd. Stent, stent graft and stent valve
US5855597A (en) 1997-05-07 1999-01-05 Iowa-India Investments Co. Limited Stent valve and stent graft for percutaneous surgery
DE19721902A1 (en) 1997-05-26 1998-12-03 Boehringer Mannheim Gmbh Method and device for in-vivo detection of the direction of Langer lines in the skin
US6409755B1 (en) 1997-05-29 2002-06-25 Scimed Life Systems, Inc. Balloon expandable stent with a self-expanding portion
US6004328A (en) 1997-06-19 1999-12-21 Solar; Ronald J. Radially expandable intraluminal stent and delivery catheter therefore and method of using the same
JP4162270B2 (en) 1997-06-27 2008-10-08 ザ トラスティーズ オブ コロンビア ユニバーシティー イン ザ シティー オブ ニューヨーク Equipment for circulation valve repair
EP0891752B1 (en) 1997-07-17 2005-01-12 Schneider (Europe) GmbH Stent and method for manufacturing such a stent
US7039446B2 (en) 2001-01-26 2006-05-02 Sensys Medical, Inc. Indirect measurement of tissue analytes through tissue properties
US6045576A (en) 1997-09-16 2000-04-04 Baxter International Inc. Sewing ring having increased annular coaptation
KR20010082497A (en) 1997-09-24 2001-08-30 메드 인스티튜트, 인코포레이티드 Radially expandable stent
US5925063A (en) 1997-09-26 1999-07-20 Khosravi; Farhad Coiled sheet valve, filter or occlusive device and methods of use
US6042606A (en) 1997-09-29 2000-03-28 Cook Incorporated Radially expandable non-axially contracting surgical stent
US6091984A (en) 1997-10-10 2000-07-18 Massachusetts Institute Of Technology Measuring tissue morphology
US5862806A (en) 1997-10-30 1999-01-26 Mitroflow International, Inc. Borohydride reduction of biological tissues
US5910170A (en) 1997-12-17 1999-06-08 St. Jude Medical, Inc. Prosthetic heart valve stent utilizing mounting clips
US6530952B2 (en) 1997-12-29 2003-03-11 The Cleveland Clinic Foundation Bioprosthetic cardiovascular valve system
US6174327B1 (en) 1998-02-27 2001-01-16 Scimed Life Systems, Inc. Stent deployment apparatus and method
US6129756A (en) 1998-03-16 2000-10-10 Teramed, Inc. Biluminal endovascular graft system
AU764536B2 (en) 1998-03-23 2003-08-21 Synovis Life Technologies, Inc. Implants and method of making
US7500988B1 (en) 2000-11-16 2009-03-10 Cordis Corporation Stent for use in a stent graft
US6290731B1 (en) 1998-03-30 2001-09-18 Cordis Corporation Aortic graft having a precursor gasket for repairing an abdominal aortic aneurysm
US6352554B2 (en) 1998-05-08 2002-03-05 Sulzer Vascutek Limited Prosthetic tubular aortic conduit and method for manufacturing the same
WO1999058082A2 (en) 1998-05-14 1999-11-18 The Cleveland Clinic Foundation Processing of implantable animal tissues for dry storage
DK1087727T3 (en) 1998-06-02 2005-01-31 Cook Inc Multilateral, intraluminal, medical device
MXPA00012064A (en) 1998-06-05 2003-04-22 Organogenesis Inc Bioengineered tubular graft prostheses.
DE69940507D1 (en) 1998-06-05 2009-04-16 Organogenesis Inc BIOTECHNICALLY GENERATED VASCOPY THERAPY FOR IMPLANTATION
KR20010052714A (en) 1998-06-11 2001-06-25 가부시끼가이샤 타픽 Collagen Material and Process for Producing the Same
US6630001B2 (en) 1998-06-24 2003-10-07 International Heart Institute Of Montana Foundation Compliant dehyrated tissue for implantation and process of making the same
US6117169A (en) 1998-06-24 2000-09-12 Sulzer Carbomedics Inc. Living hinge attachment of leaflet to a valve body
US6254636B1 (en) 1998-06-26 2001-07-03 St. Jude Medical, Inc. Single suture biological tissue aortic stentless valve
US20030217415A1 (en) 1998-06-30 2003-11-27 Katrina Crouch Plasticized bone grafts and methods of making and using same
US6293970B1 (en) 1998-06-30 2001-09-25 Lifenet Plasticized bone and soft tissue grafts and methods of making and using same
US6186999B1 (en) 1998-08-27 2001-02-13 The Cleveland Clinic Foundation Rigid clampable cannula
AU6140299A (en) 1998-09-10 2000-04-03 Percardia, Inc. Tmr shunt
US6214054B1 (en) 1998-09-21 2001-04-10 Edwards Lifesciences Corporation Method for fixation of biological tissues having mitigated propensity for post-implantation calcification and thrombosis and bioprosthetic devices prepared thereby
US7662409B2 (en) 1998-09-25 2010-02-16 Gel-Del Technologies, Inc. Protein matrix materials, devices and methods of making and using thereof
US6334873B1 (en) 1998-09-28 2002-01-01 Autogenics Heart valve having tissue retention with anchors and an outer sheath
US6168619B1 (en) 1998-10-16 2001-01-02 Quanam Medical Corporation Intravascular stent having a coaxial polymer member and end sleeves
US6214055B1 (en) 1998-10-30 2001-04-10 Mures Cardiovascular Research, Inc. Method and kit for rapid preparation of autologous tissue medical devices
US20020123789A1 (en) 1998-12-04 2002-09-05 Francis Ralph T. Stent cover
EP1022031B1 (en) 1999-01-21 2005-03-23 Nipro Corporation Suturable adhesion-preventing membrane
US6404497B1 (en) 1999-01-25 2002-06-11 Massachusetts Institute Of Technology Polarized light scattering spectroscopy of tissue
US6558418B2 (en) 1999-01-26 2003-05-06 Edwards Lifesciences Corporation Flexible heart valve
US6736845B2 (en) 1999-01-26 2004-05-18 Edwards Lifesciences Corporation Holder for flexible heart valve
US6896690B1 (en) 2000-01-27 2005-05-24 Viacor, Inc. Cardiac valve procedure methods and devices
US7018401B1 (en) 1999-02-01 2006-03-28 Board Of Regents, The University Of Texas System Woven intravascular devices and methods for making the same and apparatus for delivery of the same
US6425916B1 (en) 1999-02-10 2002-07-30 Michi E. Garrison Methods and devices for implanting cardiac valves
US6666886B1 (en) 1999-02-16 2003-12-23 Regents Of The University Of Minnesota Tissue equivalent approach to a tissue-engineered cardiovascular valve
US6342069B1 (en) 1999-03-26 2002-01-29 Mures Cardiovascular Research, Inc. Surgical instruments utilized to assemble a stentless autologous tissue heart valve
ATE484241T1 (en) 1999-04-09 2010-10-15 Evalve Inc METHOD AND DEVICE FOR HEART VALVE REPAIR
US6391333B1 (en) 1999-04-14 2002-05-21 Collagen Matrix, Inc. Oriented biopolymeric membrane
US6231602B1 (en) 1999-04-16 2001-05-15 Edwards Lifesciences Corporation Aortic annuloplasty ring
US6264691B1 (en) 1999-04-23 2001-07-24 Shlomo Gabbay Apparatus and method for supporting a heart valve
US6287335B1 (en) 1999-04-26 2001-09-11 William J. Drasler Intravascular folded tubular endoprosthesis
US6790229B1 (en) 1999-05-25 2004-09-14 Eric Berreklouw Fixing device, in particular for fixing to vascular wall tissue
US7628803B2 (en) 2001-02-05 2009-12-08 Cook Incorporated Implantable vascular device
US6241763B1 (en) 1999-06-08 2001-06-05 William J. Drasler In situ venous valve device and method of formation
AU5639700A (en) 1999-07-01 2001-01-22 Biomedical Design, Inc. Targeted anticalcification treatment
US8500795B2 (en) 1999-08-09 2013-08-06 Cardiokinetix, Inc. Retrievable devices for improving cardiac function
US6371980B1 (en) 1999-08-30 2002-04-16 Cardiovasc, Inc. Composite expandable device with impervious polymeric covering and bioactive coating thereon, delivery apparatus and method
US6312474B1 (en) 1999-09-15 2001-11-06 Bio-Vascular, Inc. Resorbable implant materials
US6312462B1 (en) 1999-09-22 2001-11-06 Impra, Inc. Prosthesis for abdominal aortic aneurysm repair
US6358275B1 (en) 1999-10-04 2002-03-19 Sulzer Carbomedics Inc. Tissue-derived vascular grafts and methods for making the same
AU1083101A (en) 1999-10-12 2001-04-23 Allan R. Will Methods and devices for protecting a passageway in a body
US6383171B1 (en) 1999-10-12 2002-05-07 Allan Will Methods and devices for protecting a passageway in a body when advancing devices through the passageway
US6352708B1 (en) 1999-10-14 2002-03-05 The International Heart Institute Of Montana Foundation Solution and method for treating autologous tissue for implant operation
US6440164B1 (en) 1999-10-21 2002-08-27 Scimed Life Systems, Inc. Implantable prosthetic valve
US7018406B2 (en) 1999-11-17 2006-03-28 Corevalve Sa Prosthetic valve for transluminal delivery
FR2800984B1 (en) 1999-11-17 2001-12-14 Jacques Seguin DEVICE FOR REPLACING A HEART VALVE PERCUTANEOUSLY
US6458153B1 (en) 1999-12-31 2002-10-01 Abps Venture One, Ltd. Endoluminal cardiac and venous valve prostheses and methods of manufacture and delivery thereof
US6432712B1 (en) 1999-11-22 2002-08-13 Bioscience Consultants, Llc Transplantable recellularized and reendothelialized vascular tissue graft
US6482240B1 (en) 1999-12-07 2002-11-19 Ed. Geistlich Soehne Ag Fur Chemische Industrie Method of making a collagen membrane from porcine skin
US20020128708A1 (en) 1999-12-09 2002-09-12 Northrup William F. Annuloplasty system
US6376244B1 (en) 1999-12-29 2002-04-23 Children's Medical Center Corporation Methods and compositions for organ decellularization
US6471723B1 (en) 2000-01-10 2002-10-29 St. Jude Medical, Inc. Biocompatible prosthetic tissue
CN1806775A (en) 2000-01-14 2006-07-26 维亚科公司 Tissue annuloplasty band and apparatus and method for fashioning, sizing and implanting the same
NL1014095C2 (en) 2000-01-17 2001-07-18 Cornelis Hendrikus Anna Witten Implant valve for implantation into a blood vessel.
HUP0204398A2 (en) 2000-01-27 2003-03-28 3F Therapeutics Prosthetic heart valve
JP4898993B2 (en) 2000-01-28 2012-03-21 クック メディカル テクノロジーズ エルエルシー Intravascular medical device with multiple wires
MXPA02007426A (en) 2000-01-31 2003-10-14 Cook Biotech Inc Stent valves and uses of same.
EP1251803B1 (en) 2000-02-02 2005-06-01 Robert V. Snyders Artificial heart valve
US6821297B2 (en) 2000-02-02 2004-11-23 Robert V. Snyders Artificial heart valve, implantation instrument and method therefor
US6378221B1 (en) 2000-02-29 2002-04-30 Edwards Lifesciences Corporation Systems and methods for mapping and marking the thickness of bioprosthetic sheet
US6454799B1 (en) 2000-04-06 2002-09-24 Edwards Lifesciences Corporation Minimally-invasive heart valves and methods of use
US20020005073A1 (en) 2000-04-20 2002-01-17 David Tompkins Method and apparatus for testing the strength of autologous tissue
US6610088B1 (en) 2000-05-03 2003-08-26 Shlomo Gabbay Biologically covered heart valve prosthesis
US6565960B2 (en) 2000-06-01 2003-05-20 Shriners Hospital Of Children Polymer composite compositions
US6840246B2 (en) 2000-06-20 2005-01-11 University Of Maryland, Baltimore Apparatuses and methods for performing minimally invasive diagnostic and surgical procedures inside of a beating heart
EP1330189B1 (en) 2000-06-23 2007-12-19 Viacor Incorporated Automated annular plication for mitral valve repair
US6676698B2 (en) 2000-06-26 2004-01-13 Rex Medicol, L.P. Vascular device with valve for approximating vessel wall
US20020073359A1 (en) 2000-09-08 2002-06-13 Wade Jennifer A. System and method for high priority machine check analysis
WO2002022054A1 (en) 2000-09-12 2002-03-21 Gabbay S Valvular prosthesis and method of using same
US7510572B2 (en) 2000-09-12 2009-03-31 Shlomo Gabbay Implantation system for delivery of a heart valve prosthesis
US20020119437A1 (en) 2000-09-20 2002-08-29 Grooms Jamie M. Method of preparing and processing transplant tissue
US6461382B1 (en) 2000-09-22 2002-10-08 Edwards Lifesciences Corporation Flexible heart valve having moveable commissures
US6932838B2 (en) 2000-09-29 2005-08-23 Tricardia, Llc Venous valvuloplasty device and method
US6913608B2 (en) 2000-10-23 2005-07-05 Viacor, Inc. Automated annular plication for mitral valve repair
US6482228B1 (en) 2000-11-14 2002-11-19 Troy R. Norred Percutaneous aortic valve replacement
US6494909B2 (en) 2000-12-01 2002-12-17 Prodesco, Inc. Endovascular valve
US6696074B2 (en) 2000-12-04 2004-02-24 Tei Biosciences, Inc. Processing fetal or neo-natal tissue to produce a scaffold for tissue engineering
AUPR217300A0 (en) 2000-12-20 2001-01-25 Ketharanathan, Vettivetpillai Method of creating biological and biosynthetic material for implantation
US20020091441A1 (en) 2001-01-05 2002-07-11 Guzik Donald S. Focused beam cutting of materials
WO2002074201A1 (en) 2001-03-16 2002-09-26 Mayo Foundation For Medical Education And Research Synthethic leaflets for heart valve repair or replacement
US6503272B2 (en) 2001-03-21 2003-01-07 Cordis Corporation Stent-based venous valves
US7556646B2 (en) 2001-09-13 2009-07-07 Edwards Lifesciences Corporation Methods and apparatuses for deploying minimally-invasive heart valves
US6773456B1 (en) 2001-03-23 2004-08-10 Endovascular Technologies, Inc. Adjustable customized endovascular graft
US6733525B2 (en) 2001-03-23 2004-05-11 Edwards Lifesciences Corporation Rolled minimally-invasive heart valves and methods of use
EP1245202B1 (en) 2001-03-27 2004-08-04 William Cook Europe ApS An aortic graft device
GB0107910D0 (en) 2001-03-29 2001-05-23 Isis Innovation Deployable stent
US7526112B2 (en) 2001-04-30 2009-04-28 Chase Medical, L.P. System and method for facilitating cardiac intervention
US7510571B2 (en) 2001-06-11 2009-03-31 Boston Scientific, Scimed, Inc. Pleated composite ePTFE/textile hybrid covering
AU2002320610A1 (en) 2001-07-16 2003-03-03 Altertek/Bio Inc Tissue engineered heart valve
US20060025800A1 (en) 2001-09-05 2006-02-02 Mitta Suresh Method and device for surgical ventricular repair
US6961123B1 (en) 2001-09-28 2005-11-01 The Texas A&M University System Method and apparatus for obtaining information from polarization-sensitive optical coherence tomography
US6893460B2 (en) 2001-10-11 2005-05-17 Percutaneous Valve Technologies Inc. Implantable prosthetic valve
US20030078659A1 (en) 2001-10-23 2003-04-24 Jun Yang Graft element
US20060020336A1 (en) 2001-10-23 2006-01-26 Liddicoat John R Automated annular plication for mitral valve repair
US8353945B2 (en) 2001-12-03 2013-01-15 J.W. Medical System Ltd. Delivery catheter having active engagement mechanism for prosthesis
US7504258B2 (en) 2001-12-11 2009-03-17 Cytograft Tissue Engineering, Inc. Tissue engineered cellular sheets, methods of making and use thereof
US20030118560A1 (en) 2001-12-20 2003-06-26 Kelly Sheila J. Composite biocompatible matrices
US6682537B2 (en) 2001-12-20 2004-01-27 The Cleveland Clinic Foundation Apparatus and method for capturing a wire in a blood vessel
US7201771B2 (en) 2001-12-27 2007-04-10 Arbor Surgical Technologies, Inc. Bioprosthetic heart valve
US7033390B2 (en) 2002-01-02 2006-04-25 Medtronic, Inc. Prosthetic heart valve system
US7189258B2 (en) 2002-01-02 2007-03-13 Medtronic, Inc. Heart valve system
US20030130729A1 (en) 2002-01-04 2003-07-10 David Paniagua Percutaneously implantable replacement heart valve device and method of making same
US8308797B2 (en) 2002-01-04 2012-11-13 Colibri Heart Valve, LLC Percutaneously implantable replacement heart valve device and method of making same
US6764510B2 (en) 2002-01-09 2004-07-20 Myocor, Inc. Devices and methods for heart valve treatment
US7018404B2 (en) 2002-01-24 2006-03-28 St. Jude Medical, Inc. Conduit for aorta or pulmonary artery replacement
EP1476095A4 (en) 2002-02-20 2007-04-25 Francisco J Osse Venous bi-valve
US7125418B2 (en) 2002-04-16 2006-10-24 The International Heart Institute Of Montana Foundation Sigmoid valve and method for its percutaneous implantation
WO2003092554A1 (en) 2002-05-03 2003-11-13 The General Hospital Corporation Involuted endovascular valve and method of construction
US7141064B2 (en) 2002-05-08 2006-11-28 Edwards Lifesciences Corporation Compressed tissue for heart valve leaflets
US6736823B2 (en) 2002-05-10 2004-05-18 C.R. Bard, Inc. Prosthetic repair fabric
US7011688B2 (en) 2002-05-10 2006-03-14 C.R. Bard, Inc. Prosthetic repair fabric
US7138226B2 (en) 2002-05-10 2006-11-21 The University Of Miami Preservation of RNA and morphology in cells and tissues
AU2003225291A1 (en) 2002-05-10 2003-11-11 Cordis Corporation Method of making a medical device having a thin wall tubular membrane over a structural frame
US7270675B2 (en) 2002-05-10 2007-09-18 Cordis Corporation Method of forming a tubular membrane on a structural frame
US20030229394A1 (en) 2002-06-06 2003-12-11 Ogle Matthew F. Processed tissue for medical device formation
US20040024452A1 (en) 2002-08-02 2004-02-05 Kruse Steven D. Valved prostheses with preformed tissue leaflets
US7041132B2 (en) 2002-08-16 2006-05-09 3F Therapeutics, Inc, Percutaneously delivered heart valve and delivery means thereof
CN1697634A (en) 2002-09-18 2005-11-16 Sdgi控股股份有限公司 Native tissue devices and transplantation methods
US7008763B2 (en) 2002-09-23 2006-03-07 Cheung David T Method to treat collagenous connective tissue for implant remodeled by host cells into living tissue
US6802806B2 (en) 2002-09-23 2004-10-12 Cleveland Clinic Foundation Apparatus for use with an inflow cannula of ventricular assist device
US7402319B2 (en) 2002-09-27 2008-07-22 Board Of Regents, The University Of Texas System Cell-free tissue replacement for tissue engineering
WO2004047687A1 (en) 2002-11-22 2004-06-10 Cook Incorporated Stent tissue graft prosthesis
US7189259B2 (en) 2002-11-26 2007-03-13 Clemson University Tissue material and process for bioprosthesis
US20040158321A1 (en) 2003-02-12 2004-08-12 Cardiac Dimensions, Inc. Method of implanting a mitral valve therapy device
US7473237B2 (en) 2003-02-25 2009-01-06 The Cleveland Clinic Foundation Apparatus for auto-retroperfusion of a coronary vein
EP1596903A2 (en) 2003-02-25 2005-11-23 The Cleveland Clinic Foundation Apparatus and method for auto-retroperfusion of a coronary vein
US7399315B2 (en) 2003-03-18 2008-07-15 Edwards Lifescience Corporation Minimally-invasive heart valve with cusp positioners
DE602004026858D1 (en) 2003-05-20 2010-06-10 Cleveland Clinic Foundation DEVICE FOR REPAIRING HEADLAPS
US8052751B2 (en) 2003-07-02 2011-11-08 Flexcor, Inc. Annuloplasty rings for repairing cardiac valves
RU2006103367A (en) 2003-07-08 2006-06-27 Вентор Текнолоджиз Лтд. (Il) IMPLANTED PROSTHETIC DEVICES, IN PARTICULAR, FOR TRANSARTHERIAL DELIVERY IN TREATMENT OF AORTAL STENOSIS AND METHODS OF IMPLANTING SUCH DEVICES
WO2005011534A1 (en) 2003-07-31 2005-02-10 Cook Incorporated Prosthetic valve devices and methods of making such devices
US7160322B2 (en) 2003-08-13 2007-01-09 Shlomo Gabbay Implantable cardiac prosthesis for mitigating prolapse of a heart valve
US6996952B2 (en) 2003-09-30 2006-02-14 Codman & Shurtleff, Inc. Method for improving stability and effectivity of a drug-device combination product
US20050075725A1 (en) 2003-10-02 2005-04-07 Rowe Stanton J. Implantable prosthetic valve with non-laminar flow
US20060259137A1 (en) 2003-10-06 2006-11-16 Jason Artof Minimally invasive valve replacement system
US20050247320A1 (en) 2003-10-10 2005-11-10 Stack Richard S Devices and methods for retaining a gastro-esophageal implant
US7053051B2 (en) 2003-10-28 2006-05-30 Medtronic, Inc. Methods of preparing crosslinked materials and bioprosthetic devices
US7232461B2 (en) 2003-10-29 2007-06-19 Cordis Neurovascular, Inc. Neck covering device for an aneurysm
US7070616B2 (en) 2003-10-31 2006-07-04 Cordis Corporation Implantable valvular prosthesis
US20050148512A1 (en) 2003-11-10 2005-07-07 Angiotech International Ag Medical implants and fibrosis-inducing agents
US8128681B2 (en) 2003-12-19 2012-03-06 Boston Scientific Scimed, Inc. Venous valve apparatus, system, and method
US7261732B2 (en) 2003-12-22 2007-08-28 Henri Justino Stent mounted valve
US7445631B2 (en) 2003-12-23 2008-11-04 Sadra Medical, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
US7381219B2 (en) 2003-12-23 2008-06-03 Sadra Medical, Inc. Low profile heart valve and delivery system
EP2745805B2 (en) 2003-12-23 2022-05-18 Boston Scientific Scimed, Inc. Repositionable heart valve
US7329279B2 (en) 2003-12-23 2008-02-12 Sadra Medical, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
US7311730B2 (en) 2004-02-13 2007-12-25 Shlomo Gabbay Support apparatus and heart valve prosthesis for sutureless implantation
US7247167B2 (en) 2004-02-19 2007-07-24 Shlomo Gabbay Low profile heart valve prosthesis
US20050228494A1 (en) 2004-03-29 2005-10-13 Salvador Marquez Controlled separation heart valve frame
JP2007530242A (en) 2004-03-29 2007-11-01 メイヨ フオンデーシヨン フオー メデイカル エジユケーシヨン アンド リサーチ Genetically engineered heart valve xenografts
US8500751B2 (en) 2004-03-31 2013-08-06 Merlin Md Pte Ltd Medical device
US7637937B2 (en) 2004-04-08 2009-12-29 Cook Incorporated Implantable medical device with optimized shape
US7289211B1 (en) 2004-04-09 2007-10-30 Walsh Jr Joseph T System and method for imaging sub-surface polarization-sensitive material structures
US7309461B2 (en) 2004-04-12 2007-12-18 Boston Scientific Scimed, Inc. Ultrasonic crimping of a varied diameter vascular graft
US7648676B2 (en) 2004-04-20 2010-01-19 Rti Biologics, Inc. Process and apparatus for treating implants comprising soft tissue
US20050267529A1 (en) 2004-05-13 2005-12-01 Heber Crockett Devices, systems and methods for tissue repair
US7462191B2 (en) 2004-06-30 2008-12-09 Edwards Lifesciences Pvt, Inc. Device and method for assisting in the implantation of a prosthetic valve
US7276078B2 (en) 2004-06-30 2007-10-02 Edwards Lifesciences Pvt Paravalvular leak detection, sealing, and prevention
EP1796584A1 (en) 2004-07-27 2007-06-20 The Cleveland Clinic Foundation Apparatus for treating atherosclerosis
JP4346521B2 (en) 2004-07-28 2009-10-21 株式会社デンソー Obstacle detection device
US7566343B2 (en) 2004-09-02 2009-07-28 Boston Scientific Scimed, Inc. Cardiac valve, system, and method
US6951571B1 (en) 2004-09-30 2005-10-04 Rohit Srivastava Valve implanting device
WO2006050459A2 (en) 2004-10-28 2006-05-11 Cook Incorporated Methods and systems for modifying vascular valves
WO2006050460A1 (en) 2004-10-29 2006-05-11 Cook Incorporated Vascular valves having implanted and target configurations and methods of preparing the same
US7771442B2 (en) 2004-11-22 2010-08-10 Edgar Louis Shriver Graft core for seal and suture anastomoses with devices and methods for percutaneous intraluminal excisional surgery (PIES)
JP2008520748A (en) 2004-11-22 2008-06-19 セレゲン,インコーポレーテッド Use of cultured three-dimensional tissue for the treatment of congestive heart failure
US20060129225A1 (en) 2004-12-15 2006-06-15 Kopia Gregory A Device for the delivery of a cardioprotective agent to ischemic reperfused myocardium
US8874204B2 (en) 2004-12-20 2014-10-28 Cardiac Pacemakers, Inc. Implantable medical devices comprising isolated extracellular matrix
JP5208513B2 (en) 2004-12-24 2013-06-12 セルクセル プロパティ リミテッド Implantable biomaterial and method of producing the same
US20060155366A1 (en) 2005-01-10 2006-07-13 Laduca Robert Apparatus and method for deploying an implantable device within the body
US7989157B2 (en) 2005-01-11 2011-08-02 Medtronic, Inc. Solution for storing bioprosthetic tissue used in a biological prosthesis
US7854755B2 (en) 2005-02-01 2010-12-21 Boston Scientific Scimed, Inc. Vascular catheter, system, and method
CA2878309C (en) 2005-02-04 2017-11-21 Ams Research Corporation Surgical implants and related methods and systems
US7914437B2 (en) 2005-02-04 2011-03-29 Ams Research Corporation Transobturator methods for installing sling to treat incontinence, and related devices
US7670368B2 (en) 2005-02-07 2010-03-02 Boston Scientific Scimed, Inc. Venous valve apparatus, system, and method
US7780722B2 (en) 2005-02-07 2010-08-24 Boston Scientific Scimed, Inc. Venous valve apparatus, system, and method
ITTO20050074A1 (en) 2005-02-10 2006-08-11 Sorin Biomedica Cardio Srl CARDIAC VALVE PROSTHESIS
US20100312333A1 (en) 2009-04-29 2010-12-09 The Cleveland Clinic Foundation Apparatus and method for replacing a diseased cardiac valve
WO2006089236A1 (en) 2005-02-18 2006-08-24 The Cleveland Clinic Foundation Apparatus and methods for replacing a cardiac valve
US7867274B2 (en) 2005-02-23 2011-01-11 Boston Scientific Scimed, Inc. Valve apparatus, system and method
US9216236B2 (en) 2005-03-07 2015-12-22 Technion Research & Development Foundation Limited Natural tissue-derived decellularized matrix and methods of generating and using same
US20060206203A1 (en) 2005-03-10 2006-09-14 Jun Yang Valvular support prosthesis
US20060229701A1 (en) 2005-03-14 2006-10-12 The Cleveland Clinic Foundation Apparatus for use with expandable stents
CN2812872Y (en) * 2005-04-05 2006-09-06 王文林 Folding heart mechanical valve
US7462156B2 (en) 2005-04-11 2008-12-09 Zan Mitrev Replacement aortic valve leaflets and related technology
EP1893131A1 (en) 2005-04-20 2008-03-05 The Cleveland Clinic Foundation Apparatus and method for replacing a cardiac valve
DE102005020648A1 (en) 2005-05-03 2006-11-16 Sartorius Ag Connector, connector system and use
US7164145B2 (en) 2005-05-12 2007-01-16 Honeywell International Inc. Measuring fiber orientation by detecting dispersion of polarized light
US7914569B2 (en) 2005-05-13 2011-03-29 Medtronics Corevalve Llc Heart valve prosthesis and methods of manufacture and use
DE102005023599A1 (en) 2005-05-18 2006-11-23 Corlife Gbr (Vertretungsberechtigte Gesellschafter: Prof. Dr. Alex Haverich Bioartificial heart tissue graft and process for its preparation
EP3292838A1 (en) 2005-05-24 2018-03-14 Edwards Lifesciences Corporation Rapid deployment prosthetic heart valve
CA2612188A1 (en) 2005-06-17 2007-01-04 Theregen, Inc. Methods for treating ischemic tissue
US8951285B2 (en) 2005-07-05 2015-02-10 Mitralign, Inc. Tissue anchor, anchoring system and methods of using the same
US20070043434A1 (en) 2005-08-18 2007-02-22 David Meerkin Biodegradable endovascular stent using stereocomplexation of polymers
US8470022B2 (en) 2005-08-31 2013-06-25 Cook Biotech Incorporated Implantable valve
US7530253B2 (en) 2005-09-09 2009-05-12 Edwards Lifesciences Corporation Prosthetic valve crimping device
US7712606B2 (en) 2005-09-13 2010-05-11 Sadra Medical, Inc. Two-part package for medical implant
WO2007035843A2 (en) 2005-09-21 2007-03-29 Dask Technologies, Llc Methods and compositions for organ and tissue functionality
US20080190989A1 (en) 2005-10-03 2008-08-14 Crews Samuel T Endoscopic plication device and method
US8167932B2 (en) 2005-10-18 2012-05-01 Edwards Lifesciences Corporation Heart valve delivery system with valve catheter
US8398306B2 (en) 2005-11-07 2013-03-19 Kraft Foods Global Brands Llc Flexible package with internal, resealable closure feature
EP1797843A1 (en) 2005-12-14 2007-06-20 Thomas Ischinger Lesion specific stents, also for ostial lesions, and methods of application
US20070213813A1 (en) 2005-12-22 2007-09-13 Symetis Sa Stent-valves for valve replacement and associated methods and systems for surgery
US9717468B2 (en) 2006-01-10 2017-08-01 Mediguide Ltd. System and method for positioning an artificial heart valve at the position of a malfunctioning valve of a heart through a percutaneous route
US8147541B2 (en) 2006-02-27 2012-04-03 Aortx, Inc. Methods and devices for delivery of prosthetic heart valves and other prosthetics
US8496700B2 (en) 2006-03-23 2013-07-30 Edrich Health Technologies, Inc. Aortic valve replacement
US8075615B2 (en) * 2006-03-28 2011-12-13 Medtronic, Inc. Prosthetic cardiac valve formed from pericardium material and methods of making same
US9005220B2 (en) 2006-04-04 2015-04-14 C.R. Bard, Inc. Suturing devices and methods with energy emitting elements
US20080039871A1 (en) 2006-04-04 2008-02-14 Wallace Jeffrey M Minimally invasive gastric restriction methods
CA2649705C (en) 2006-04-19 2015-12-01 William A. Cook Australia Pty. Ltd Twin bifurcated stent graft
US8425584B2 (en) 2006-04-21 2013-04-23 W. L. Gore & Associates, Inc. Expandable covered stent with wide range of wrinkle-free deployed diameters
US7460248B2 (en) 2006-05-15 2008-12-02 Carestream Health, Inc. Tissue imaging system
CA2654314A1 (en) 2006-06-01 2007-12-06 Mor Research Applications Ltd. Methods and devices for treatment of cardiac valves
US20080009667A1 (en) 2006-06-08 2008-01-10 Ams Research Corporation Methods and apparatus for prolapse repair and hysterectomy
US20080004686A1 (en) 2006-06-30 2008-01-03 Cook Incorporated Implantable device with light-transmitting material
US20080039926A1 (en) 2006-08-11 2008-02-14 Majercak David C Stent graft sealing zone connecting structure
AU2007292273A1 (en) * 2006-09-06 2008-03-13 Aortx, Inc. Prosthetic heart valves, systems and methods of implanting
US8876894B2 (en) 2006-09-19 2014-11-04 Medtronic Ventor Technologies Ltd. Leaflet-sensitive valve fixation member
US8834564B2 (en) 2006-09-19 2014-09-16 Medtronic, Inc. Sinus-engaging valve fixation member
WO2008042441A1 (en) 2006-10-03 2008-04-10 Anthrogenesis Corporation Use of umbilical cord biomaterial for ocular surgery
EP2076214A2 (en) 2006-10-03 2009-07-08 Alure Medical, Inc. Minimally invasive tissue support
WO2008073582A2 (en) 2006-10-27 2008-06-19 Edwards Lifesciences Corporation Biological tissue for surgical implantation
WO2008063537A2 (en) 2006-11-17 2008-05-29 St. Jude Medical, Inc. Prosthetic heart valve structures and related methods
WO2008082527A1 (en) 2006-12-19 2008-07-10 Structural Graphics, Llc Product holding and dispensing system
US8070799B2 (en) 2006-12-19 2011-12-06 Sorin Biomedica Cardio S.R.L. Instrument and method for in situ deployment of cardiac valve prostheses
US8236045B2 (en) 2006-12-22 2012-08-07 Edwards Lifesciences Corporation Implantable prosthetic valve assembly and method of making the same
WO2008089365A2 (en) 2007-01-19 2008-07-24 The Cleveland Clinic Foundation Method for implanting a cardiovascular valve
US8303649B2 (en) 2007-01-29 2012-11-06 Cook Medical Technologies Llc Artificial venous valve with discrete shaping members
WO2008094706A2 (en) 2007-02-01 2008-08-07 Cook Incorporated Closure device and method of closing a bodily opening
ATE515244T1 (en) 2007-02-15 2011-07-15 Cook Inc ARTIFICIAL VALVE PROSTHESIS WITH FREE LEAF SECTION
US20080208327A1 (en) 2007-02-27 2008-08-28 Rowe Stanton J Method and apparatus for replacing a prosthetic valve
RU2355361C2 (en) 2007-05-10 2009-05-20 Закрытое акционерное общество "НеоКор" (ЗАО "НеоКор") Heart valve bioprosthesis and method for making thereof
US8747458B2 (en) 2007-08-20 2014-06-10 Medtronic Ventor Technologies Ltd. Stent loading tool and method for use thereof
EP2219558B8 (en) 2007-08-21 2015-09-23 Symetis SA Stent-valves for valve replacement and associated systems for surgery
US20090093876A1 (en) 2007-08-31 2009-04-09 Edwards Lifesciences Corporation Recoil inhibitor for prosthetic valve
US20090062907A1 (en) 2007-08-31 2009-03-05 Quijano Rodolfo C Self-expanding valve for the venous system
US9848981B2 (en) 2007-10-12 2017-12-26 Mayo Foundation For Medical Education And Research Expandable valve prosthesis with sealing mechanism
CA2702672C (en) 2007-10-15 2016-03-15 Edwards Lifesciences Corporation Transcatheter heart valve with micro-anchors
EP2231070B1 (en) 2007-12-14 2013-05-22 Edwards Lifesciences Corporation Leaflet attachment frame for a prosthetic valve
US8357387B2 (en) 2007-12-21 2013-01-22 Edwards Lifesciences Corporation Capping bioprosthetic tissue to reduce calcification
WO2009094373A1 (en) 2008-01-22 2009-07-30 Cook Incorporated Valve frame
EP2254513B1 (en) 2008-01-24 2015-10-28 Medtronic, Inc. Stents for prosthetic heart valves
US9241792B2 (en) 2008-02-29 2016-01-26 Edwards Lifesciences Corporation Two-step heart valve implantation
US8313525B2 (en) 2008-03-18 2012-11-20 Medtronic Ventor Technologies, Ltd. Valve suturing and implantation procedures
US20090254175A1 (en) 2008-04-03 2009-10-08 Quijano Rodolfo C Valved stent for chronic venous insufficiency
BRPI0911351B8 (en) 2008-04-23 2021-06-22 Medtronic Inc stent frame for a prosthetic heart valve, and heart valve prosthesis
CA3272264A1 (en) 2008-06-06 2025-10-30 Edwards Lifesciences Corporation Low profile transcatheter heart valve
US8323335B2 (en) 2008-06-20 2012-12-04 Edwards Lifesciences Corporation Retaining mechanisms for prosthetic valves and methods for using
WO2009156471A1 (en) 2008-06-26 2009-12-30 Iberhospitex, S.A. Prosthetic heart valve and method for making such a valve
EP2815724B2 (en) * 2008-07-15 2024-03-13 St. Jude Medical, Inc. Collapsible and re-expandable prosthetic heart valve cuff designs and complementary technological applications
AU2009274131B2 (en) 2008-07-21 2015-06-04 Jennifer K. White Repositionable endoluminal support structure and its applications
AU2009276505B2 (en) 2008-08-01 2015-04-23 Intersect Ent, Inc. Methods and devices for crimping self-expanding devices
US8652202B2 (en) 2008-08-22 2014-02-18 Edwards Lifesciences Corporation Prosthetic heart valve and delivery apparatus
JP5611948B2 (en) 2008-08-25 2014-10-22 カーディオキネティックス・インコーポレイテッドCardiokinetix, Inc. Recoverable heart device
WO2010027363A1 (en) 2008-09-05 2010-03-11 Merlin Md Pte Ltd Endovascular device
CN102292053A (en) 2008-09-29 2011-12-21 卡迪尔克阀门技术公司 Heart valve
US9119715B2 (en) 2008-10-30 2015-09-01 St. Jude Medical, Inc. Collapsible/expandable prosthetic heart valve delivery system and methods
US20110240511A1 (en) 2008-12-10 2011-10-06 Merck Sharp & Dohme Corp. Packaging for oxygen-sensitive pharmaceutical products
US8308798B2 (en) 2008-12-19 2012-11-13 Edwards Lifesciences Corporation Quick-connect prosthetic heart valve and methods
EP2201911B1 (en) 2008-12-23 2015-09-30 Sorin Group Italia S.r.l. Expandable prosthetic valve having anchoring appendages
US20100217382A1 (en) 2009-02-25 2010-08-26 Edwards Lifesciences Mitral valve replacement with atrial anchoring
US8029534B2 (en) 2009-03-16 2011-10-04 Cook Medical Technologies Llc Closure device with string retractable umbrella
US20100241069A1 (en) 2009-03-19 2010-09-23 Abbott Cardiovascular Systems Inc. Ostial lesion stent delivery system
CN101919753A (en) 2009-03-30 2010-12-22 卡迪万蒂奇医药公司 Method and device for sutureless implantation of artificial aortic valve or mitral valve
US9066785B2 (en) 2009-04-06 2015-06-30 Medtronic Vascular, Inc. Packaging systems for percutaneously deliverable bioprosthetic valves
US8468667B2 (en) 2009-05-15 2013-06-25 Jenavalve Technology, Inc. Device for compressing a stent
WO2010141847A1 (en) * 2009-06-05 2010-12-09 Ats Medical, Inc. Flexible commissure structure for attaching valve bioprosthesis
CA2767035C (en) 2009-07-02 2015-07-21 The Cleveland Clinic Foundation Apparatus and method for replacing a diseased cardiac valve
US8475522B2 (en) 2009-07-14 2013-07-02 Edwards Lifesciences Corporation Transapical delivery system for heart valves
US20110146361A1 (en) 2009-12-22 2011-06-23 Edwards Lifesciences Corporation Method of Peening Metal Heart Valve Stents
EP2542668A2 (en) 2010-03-01 2013-01-09 Colibri Heart Valve LLC Tissue for prosthetic implants and grafts, and methods associated therewith
US8795354B2 (en) 2010-03-05 2014-08-05 Edwards Lifesciences Corporation Low-profile heart valve and delivery system
EP2544753B1 (en) 2010-03-10 2019-01-09 The Cleveland Clinic Foundation Catheter assembly
US8512401B2 (en) 2010-04-12 2013-08-20 Medtronic, Inc. Transcatheter prosthetic heart valve delivery system with funnel recapturing feature and method
US8579964B2 (en) 2010-05-05 2013-11-12 Neovasc Inc. Transcatheter mitral valve prosthesis
US9119738B2 (en) 2010-06-28 2015-09-01 Colibri Heart Valve Llc Method and apparatus for the endoluminal delivery of intravascular devices
CN101917721B (en) 2010-08-16 2014-09-10 中兴通讯股份有限公司 Regional access platform, mobile positioning method and system
AU2011305153A1 (en) 2010-09-23 2013-05-02 Colibri Heart Valve Llc Percutaneously deliverable heart or blood vessel valve with frame having abluminally situated tissue membrane
CN105380730B (en) 2010-10-05 2018-08-17 爱德华兹生命科学公司 Heart valve prosthesis
PL3593762T3 (en) 2010-10-05 2021-05-04 Edwards Lifesciences Corporation HEART RESTRAINT AND DEVICE FOR INSERTION
SG191008A1 (en) * 2010-12-14 2013-07-31 Colibri Heart Valve Llc Percutaneously deliverable heart valve including folded membrane cusps with integral leaflets
US9498317B2 (en) 2010-12-16 2016-11-22 Edwards Lifesciences Corporation Prosthetic heart valve delivery systems and packaging
US9119716B2 (en) 2011-07-27 2015-09-01 Edwards Lifesciences Corporation Delivery systems for prosthetic heart valve

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5509930A (en) * 1993-12-17 1996-04-23 Autogenics Stentless heart valve
US20090112309A1 (en) * 2005-07-21 2009-04-30 The Florida International University Board Of Trustees Collapsible Heart Valve with Polymer Leaflets
US20070043431A1 (en) * 2005-08-19 2007-02-22 Cook Incorporated Prosthetic valve
US20100185277A1 (en) * 2007-09-26 2010-07-22 St. Jude Medical, Inc. Collapsible prosthetic heart valves
WO2011109450A2 (en) * 2010-03-01 2011-09-09 Colibri Heart Valve Llc Percutaneously deliverable heart valve and methods associated therewith

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8900294B2 (en) 2002-01-04 2014-12-02 Colibri Heart Valve Llc Method of controlled release of a percutaneous replacement heart valve
US9125739B2 (en) 2002-01-04 2015-09-08 Colibri Heart Valve Llc Percutaneous replacement heart valve and a delivery and implantation system
US9554898B2 (en) 2002-01-04 2017-01-31 Colibri Heart Valve Llc Percutaneous prosthetic heart valve
US9119738B2 (en) 2010-06-28 2015-09-01 Colibri Heart Valve Llc Method and apparatus for the endoluminal delivery of intravascular devices

Also Published As

Publication number Publication date
CN103391756A (en) 2013-11-13
JP2018075427A (en) 2018-05-17
CA3027755C (en) 2021-05-11
US12564490B2 (en) 2026-03-03
US20120185038A1 (en) 2012-07-19
US20210228347A1 (en) 2021-07-29
SG10201601962WA (en) 2016-04-28
SG191008A1 (en) 2013-07-31
JP6691907B2 (en) 2020-05-13
AU2011343755A1 (en) 2013-06-06
JP2020114495A (en) 2020-07-30
WO2012082952A2 (en) 2012-06-21
US9737400B2 (en) 2017-08-22
CA3027755A1 (en) 2012-06-21
CN103391756B (en) 2016-06-01
JP2014507179A (en) 2014-03-27
US10973632B2 (en) 2021-04-13
US20180185143A1 (en) 2018-07-05
CA2820738A1 (en) 2012-06-21
CA2820738C (en) 2019-01-15

Similar Documents

Publication Publication Date Title
WO2012082952A3 (en) Percutaneously deliverable heart valve including folded membrane cusps with integral leaflets
WO2012039753A3 (en) Valve leaflet attachment in collapsible prosthetic valves
WO2011143473A3 (en) Low gradient prosthetic heart valve
WO2009149462A8 (en) Low profile transcatheter heart valve
EP4245260A3 (en) Prosthetic mitral valve
EP4570216A3 (en) Valve prosthesis
EP4233794A3 (en) Mitral valve prosthesis for transcatheter valve implantation
CA2995038C (en) Multi-frame prosthetic heart valve
EP4537793A3 (en) Prosthetic heart valve having leaflet inflow below frame
US20160045314A1 (en) Cardiac valve commissure brace
WO2013013021A3 (en) Prosthetic heart valve
WO2011156714A3 (en) Systems for preventing formation of blood clots in the left atrium
WO2013175468A3 (en) Prosthetic mitral valve
EP4403139A3 (en) Delivery catheter system with micro and macro movement control
WO2012021527A3 (en) Temporary sub-valvular check valve
WO2012047644A3 (en) Prosthetic heart valve frame with flexible commissures
WO2014105741A8 (en) Surgical heart valves adapted for post implant expansion
WO2013021375A3 (en) Percutaneous mitral valve replacement and sealing
WO2013019756A3 (en) Artificial valved conduits for cardiac reconstructive procedures and methods for their production
EP4609835A3 (en) Prosthetic heart valve leaflet commissure assemblies and methods
WO2012061809A3 (en) Methods and systems for delivering prostheses using rail techniques
JP2012532661A5 (en)
EP4279031A3 (en) Integral flushing solution for blood stasis prevention in artificial heart valves
HK40108277A (en) Expandable prosthetic heart valve with flattened apices
Cebotari et al. Human endothelial progenitor cells seeded on allogenic heart valve scaffolds: First results 6 months after implantation

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 11848038

Country of ref document: EP

Kind code of ref document: A2

ENP Entry into the national phase

Ref document number: 2820738

Country of ref document: CA

Ref document number: 2011343755

Country of ref document: AU

Date of ref document: 20111214

Kind code of ref document: A

ENP Entry into the national phase

Ref document number: 2013544758

Country of ref document: JP

Kind code of ref document: A

NENP Non-entry into the national phase

Ref country code: DE

WWE Wipo information: entry into national phase

Ref document number: 2011848038

Country of ref document: EP