WO2012061754A3 - Composés et procédés pour traiter des maladies auto-immunes - Google Patents

Composés et procédés pour traiter des maladies auto-immunes Download PDF

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Publication number
WO2012061754A3
WO2012061754A3 PCT/US2011/059405 US2011059405W WO2012061754A3 WO 2012061754 A3 WO2012061754 A3 WO 2012061754A3 US 2011059405 W US2011059405 W US 2011059405W WO 2012061754 A3 WO2012061754 A3 WO 2012061754A3
Authority
WO
WIPO (PCT)
Prior art keywords
compounds
methods
autoimmune diseases
treating autoimmune
treating
Prior art date
Application number
PCT/US2011/059405
Other languages
English (en)
Other versions
WO2012061754A2 (fr
Inventor
Bridget Wagner
Jeremy Duvall
Danny Hung-Chieh Chou
Original Assignee
The Broad Institute, Inc.
President And Fellows Of Harvard College
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Broad Institute, Inc., President And Fellows Of Harvard College filed Critical The Broad Institute, Inc.
Publication of WO2012061754A2 publication Critical patent/WO2012061754A2/fr
Publication of WO2012061754A3 publication Critical patent/WO2012061754A3/fr
Priority to US13/887,466 priority Critical patent/US8741905B2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D267/22—Eight-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

L'invention concerne un composé de Formule I :
PCT/US2011/059405 2010-11-05 2011-11-04 Composés et procédés pour traiter des maladies auto-immunes WO2012061754A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US13/887,466 US8741905B2 (en) 2010-11-05 2013-05-06 Compounds and methods for treating autoimmune diseases

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US41055810P 2010-11-05 2010-11-05
US61/410,558 2010-11-05

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US13/887,466 Continuation US8741905B2 (en) 2010-11-05 2013-05-06 Compounds and methods for treating autoimmune diseases

Publications (2)

Publication Number Publication Date
WO2012061754A2 WO2012061754A2 (fr) 2012-05-10
WO2012061754A3 true WO2012061754A3 (fr) 2012-08-02

Family

ID=46025143

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2011/059405 WO2012061754A2 (fr) 2010-11-05 2011-11-04 Composés et procédés pour traiter des maladies auto-immunes

Country Status (1)

Country Link
WO (1) WO2012061754A2 (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8759298B2 (en) 2010-05-03 2014-06-24 Scott & White Healthcare Protein therapy for corneal inflammation, epithelial wound healing, and photoreceptor degeneration
EP2934531A4 (fr) * 2012-12-19 2016-06-15 Glaxosmithkline Llc Combinaison
AU2013370417A1 (en) 2012-12-28 2015-07-16 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Inhibitors of the USP1/UAF1 deubiquitinase complex and uses thereof
EP2816356A1 (fr) * 2013-06-17 2014-12-24 Ruprecht-Karls-Universität Heidelberg Traitement de la résistance à l'insuline par des inhibiteurs du facteur de transcription TSC22D4
CN111689923B (zh) * 2019-03-12 2022-11-08 中国科学院上海药物研究所 一个具有逆转肿瘤多药耐药活性的环脂肽化合物、其制备方法及用途
CN114272378B (zh) * 2020-09-27 2023-06-23 四川大学华西医院 一种使cttnbp2nl功能缺失的试剂在制备治疗疾病的药物中的用途
KR102312619B1 (ko) * 2020-09-28 2021-10-14 경상국립대학교산학협력단 Arl6ip5 단백질을 유효성분으로 함유하는 암의 예방, 개선 또는 치료용 조성물
EP4247941A1 (fr) * 2020-11-19 2023-09-27 The Johns Hopkins University Cibles d'immuno-oncologie pour améliorer la réponse métabolique des lymphocytes t
CN113447656B (zh) * 2021-07-01 2022-05-13 浙江大学 检测抗丝状肌动蛋白成帽蛋白β-IgG抗体的试剂盒
CN113508807B (zh) * 2021-08-05 2022-03-04 信阳农林学院 一种卵巢常温保存液及其保存方法
CN113750219B (zh) * 2021-09-09 2023-01-17 中国人民解放军海军军医大学 Tmem184c在制备预防或治疗乙型脑炎病毒感染药物中的应用

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4318909A (en) * 1980-01-17 1982-03-09 John Wyeth & Brother Limited Benzoxazocines
US20040029850A1 (en) * 2000-09-28 2004-02-12 Peter Bernstein Cyclized benzamide neurokinin antagonists for use in therapy
US20060019940A1 (en) * 2002-12-20 2006-01-26 Baxter Andrew D Novel benzoxazocines and their therapeutic use
US7625887B2 (en) * 2003-01-28 2009-12-01 Takeda Pharmaceutical Company Limited Receptor agonists

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4318909A (en) * 1980-01-17 1982-03-09 John Wyeth & Brother Limited Benzoxazocines
US20040029850A1 (en) * 2000-09-28 2004-02-12 Peter Bernstein Cyclized benzamide neurokinin antagonists for use in therapy
US20060019940A1 (en) * 2002-12-20 2006-01-26 Baxter Andrew D Novel benzoxazocines and their therapeutic use
US7625887B2 (en) * 2003-01-28 2009-12-01 Takeda Pharmaceutical Company Limited Receptor agonists

Also Published As

Publication number Publication date
WO2012061754A2 (fr) 2012-05-10

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