WO2012036520A3 - Novel antibiotically active compound and an antibiotic composition comprising the compound - Google Patents

Novel antibiotically active compound and an antibiotic composition comprising the compound Download PDF

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Publication number
WO2012036520A3
WO2012036520A3 PCT/KR2011/006881 KR2011006881W WO2012036520A3 WO 2012036520 A3 WO2012036520 A3 WO 2012036520A3 KR 2011006881 W KR2011006881 W KR 2011006881W WO 2012036520 A3 WO2012036520 A3 WO 2012036520A3
Authority
WO
WIPO (PCT)
Prior art keywords
compound
antibiotic composition
antibiotically active
active compound
novel
Prior art date
Application number
PCT/KR2011/006881
Other languages
French (fr)
Korean (ko)
Other versions
WO2012036520A2 (en
Inventor
강린우
김정구
안예진
이병무
Original Assignee
건국대학교 산학협력단
대한민국(농촌진흥청장)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 건국대학교 산학협력단, 대한민국(농촌진흥청장) filed Critical 건국대학교 산학협력단
Publication of WO2012036520A2 publication Critical patent/WO2012036520A2/en
Publication of WO2012036520A3 publication Critical patent/WO2012036520A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/60—Three or more oxygen or sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/04—Derivatives of thiourea
    • C07C335/24—Derivatives of thiourea containing any of the groups, X being a hetero atom, Y being any atom
    • C07C335/26—Y being a hydrogen or a carbon atom, e.g. benzoylthioureas
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention relates to a novel antibiotically active compound and to an antibiotic composition comprising the compound, and more specifically relates to a compound that inhibits microorganism lipid synthesis and to a use for the compound.
PCT/KR2011/006881 2010-09-17 2011-09-16 Novel antibiotically active compound and an antibiotic composition comprising the compound WO2012036520A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020100092040A KR101289461B1 (en) 2010-09-17 2010-09-17 Novel compound and Antibiotic Composition comprising the same
KR10-2010-0092040 2010-09-17

Publications (2)

Publication Number Publication Date
WO2012036520A2 WO2012036520A2 (en) 2012-03-22
WO2012036520A3 true WO2012036520A3 (en) 2012-08-23

Family

ID=45832136

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2011/006881 WO2012036520A2 (en) 2010-09-17 2011-09-16 Novel antibiotically active compound and an antibiotic composition comprising the compound

Country Status (2)

Country Link
KR (1) KR101289461B1 (en)
WO (1) WO2012036520A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101523305B1 (en) * 2013-10-11 2015-05-27 건국대학교 산학협력단 Novel compound and Antibiotic Composition comprising the same
KR101542454B1 (en) * 2013-10-11 2015-08-06 건국대학교 산학협력단 Novel compound and Antibiotic Composition comprising the same

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003074497A1 (en) * 2002-03-01 2003-09-12 Pintex Pharmaceutical, Inc. Pin1-modulating compounds and methods of use thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003074497A1 (en) * 2002-03-01 2003-09-12 Pintex Pharmaceutical, Inc. Pin1-modulating compounds and methods of use thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CUI, HUAQING ET AL.: "Exploring new inhibitors of Plasmodium falciparum purine nucleoside phosphorylase.", EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 45, 14 August 2010 (2010-08-14), pages 5140 - 5149 *
STEBBINS, JOIN L. ET AL.: "A Structure-based Approach to Retinoid X Receptor-a Inhibition.", THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 281, no. 24, 2006, pages 16643 - 16648 *

Also Published As

Publication number Publication date
KR20120029909A (en) 2012-03-27
KR101289461B1 (en) 2013-07-24
WO2012036520A2 (en) 2012-03-22

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