WO2011143772A9 - Inhibitors of hiv replication - Google Patents

Inhibitors of hiv replication Download PDF

Info

Publication number
WO2011143772A9
WO2011143772A9 PCT/CA2011/050308 CA2011050308W WO2011143772A9 WO 2011143772 A9 WO2011143772 A9 WO 2011143772A9 CA 2011050308 W CA2011050308 W CA 2011050308W WO 2011143772 A9 WO2011143772 A9 WO 2011143772A9
Authority
WO
WIPO (PCT)
Prior art keywords
inhibitors
hiv replication
hiv
replication
compounds
Prior art date
Application number
PCT/CA2011/050308
Other languages
French (fr)
Other versions
WO2011143772A1 (en
Inventor
Olivier Lepage
Punit K. Bhardwaj
Anne-Marie Faucher
Chantal Grand-Maitre
Jean-Eric Lacoste
Louie Lamorte
Jean-François MERCIER
Original Assignee
Boehringer Ingelheim International Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim International Gmbh filed Critical Boehringer Ingelheim International Gmbh
Publication of WO2011143772A1 publication Critical patent/WO2011143772A1/en
Publication of WO2011143772A9 publication Critical patent/WO2011143772A9/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Abstract

Compounds of formula (I) wherein R1, R2, n and R3 are defined herein, are useful as inhibitors of HIV replication.
PCT/CA2011/050308 2010-05-21 2011-05-17 Inhibitors of hiv replication WO2011143772A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US34714110P 2010-05-21 2010-05-21
US61/347,141 2010-05-21

Publications (2)

Publication Number Publication Date
WO2011143772A1 WO2011143772A1 (en) 2011-11-24
WO2011143772A9 true WO2011143772A9 (en) 2012-12-20

Family

ID=44991137

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CA2011/050308 WO2011143772A1 (en) 2010-05-21 2011-05-17 Inhibitors of hiv replication

Country Status (1)

Country Link
WO (1) WO2011143772A1 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2553449T3 (en) 2011-07-06 2015-12-09 Gilead Sciences, Inc. Compounds for HIV treatment
TWI706945B (en) 2013-03-01 2020-10-11 美商基利科學股份有限公司 Therapeutic compounds for treating a retroviridae viral infection
TWI652014B (en) * 2013-09-13 2019-03-01 美商艾佛艾姆希公司 Heterocyclic substituted bicycloazole insecticide
US10202353B2 (en) 2014-02-28 2019-02-12 Gilead Sciences, Inc. Therapeutic compounds
JP6716785B2 (en) 2016-08-19 2020-07-01 ギリアード サイエンシーズ， インコーポレイテッド Therapeutic compounds useful for prophylactic or therapeutic treatment of HIV viral infections
AR112412A1 (en) 2017-08-17 2019-10-23 Gilead Sciences Inc CHOLINE SALT FORMS OF AN HIV CAPSID INHIBITOR
TW202024061A (en) 2017-08-17 2020-07-01 美商基利科學股份有限公司 Solid forms of an hiv capsid inhibitor
CA3089590C (en) 2018-02-15 2022-12-06 Gilead Sciences, Inc. Pyridine derivatives and their use for treating hiv infection
CA3175557A1 (en) 2018-02-16 2019-08-22 Gilead Sciences, Inc. Methods and intermediates for preparing a therapeutic compound useful in the treatment of retroviridae viral infection
TW202033196A (en) 2018-07-16 2020-09-16 美商基利科學股份有限公司 Capsid inhibitors for the treatment of hiv
WO2021108544A1 (en) 2019-11-26 2021-06-03 Gilead Sciences, Inc. Capsid inhibitors for the prevention of hiv
CA3181690A1 (en) 2020-06-25 2021-12-30 Chienhung CHOU Capsid inhibitors for the treatment of hiv
US11787825B2 (en) 2021-12-03 2023-10-17 Gilead Sciences, Inc. Therapeutic compounds for HIV virus infection

Also Published As

Publication number Publication date
WO2011143772A1 (en) 2011-11-24

Similar Documents

Publication Publication Date Title
WO2011143772A9 (en) Inhibitors of hiv replication
WO2011153157A3 (en) Benzoquinolone inhibitors of vmat2
WO2012122011A3 (en) Amino-quinolines as kinase inhibitors
WO2011113798A3 (en) Inhibitors of semicarabazide - sensitive amine oxidase
EP3329919A8 (en) Acc inhibitors and uses thereof
UA104885C2 (en) Isothiazolyloxyphenyl amidines and use thereof as fungicides
WO2009156462A3 (en) Organic compounds
WO2011088027A8 (en) Compounds and methods
MX2019010602A (en) Cdk inhibitors.
WO2012106534A3 (en) Hiv integrase inhibitors
MX2013004491A (en) Boronates as arginase inhibitors.
WO2012065019A3 (en) Combination comprising pyridopyrimidinone inhibitors of pi3k alpha
WO2012065057A3 (en) Phosphatidylinositol 3-kinase inhibitors and methods of their use
CA2873723A1 (en) Pyrrolopyrimidone and pyrrolopyridone inhibitors of tankyrase
EP2566477A4 (en) Amino-quinolines as kinase inhibitors
MX2011007998A (en) Novel herbicides.
MY161132A (en) Novel herbicides
MY186599A (en) Substituted pyridopyrazines as novel syk inhibitors
MX2012004780A (en) Akt inhibitors.
WO2011113060A3 (en) Antiviral compounds and methods of use thereof
UA102289C2 (en) Herbicides obtained of cyclopentadione
WO2012101011A3 (en) New aryl-benzocycloalkyl amide derivatives
MX2011007932A (en) Novel herbicides.
WO2010068292A8 (en) Azaindole derivatives as kinase inhibitors
WO2012071520A3 (en) Fungicidal compositions and methods

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 11782829

Country of ref document: EP

Kind code of ref document: A1

NENP Non-entry into the national phase in:

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 11782829

Country of ref document: EP

Kind code of ref document: A1