WO2012034076A3 - Etv1 as a diagnostic, prognostic and therapeutic target for gastrointestinal stromal tumors - Google Patents

Etv1 as a diagnostic, prognostic and therapeutic target for gastrointestinal stromal tumors Download PDF

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Publication number
WO2012034076A3
WO2012034076A3 PCT/US2011/051089 US2011051089W WO2012034076A3 WO 2012034076 A3 WO2012034076 A3 WO 2012034076A3 US 2011051089 W US2011051089 W US 2011051089W WO 2012034076 A3 WO2012034076 A3 WO 2012034076A3
Authority
WO
WIPO (PCT)
Prior art keywords
prognostic
diagnostic
etv1
gastrointestinal stromal
stromal tumors
Prior art date
Application number
PCT/US2011/051089
Other languages
French (fr)
Other versions
WO2012034076A2 (en
Inventor
Ping Chi
Yu Chen
Charles Sawyers
C. David Allis
Original Assignee
Sloan-Kettering Institute For Cancer Research
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sloan-Kettering Institute For Cancer Research filed Critical Sloan-Kettering Institute For Cancer Research
Publication of WO2012034076A2 publication Critical patent/WO2012034076A2/en
Publication of WO2012034076A3 publication Critical patent/WO2012034076A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/136—Screening for pharmacological compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Abstract

Uses of ETVl for diagnostic, prognostic or therapeutic purposes with gastrointestinal stromal tumors (GISTs).
PCT/US2011/051089 2010-09-09 2011-09-09 Etv1 as a diagnostic, prognostic and therapeutic target for gastrointestinal stromal tumors WO2012034076A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US40301610P 2010-09-09 2010-09-09
US61/403,016 2010-09-09

Publications (2)

Publication Number Publication Date
WO2012034076A2 WO2012034076A2 (en) 2012-03-15
WO2012034076A3 true WO2012034076A3 (en) 2012-06-07

Family

ID=45811188

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2011/051089 WO2012034076A2 (en) 2010-09-09 2011-09-09 Etv1 as a diagnostic, prognostic and therapeutic target for gastrointestinal stromal tumors

Country Status (1)

Country Link
WO (1) WO2012034076A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013036755A1 (en) * 2011-09-09 2013-03-14 Sloan-Kettering Institute For Cancer Research Etv1 antibodies and uses thereof
CN112082976A (en) * 2019-06-14 2020-12-15 天津方得生物科技有限公司 In-vitro drug sensitivity detection method based on drug probe and tissue slice

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5718577A (en) * 1996-03-15 1998-02-17 Minnesota Mining & Manufacturing Dental impression tray with chemiluminescent light source
US5772432A (en) * 1996-10-18 1998-06-30 Minnesota Mining & Manufacturing Co. Dental impression tray with improved adhesion to impression material
US20030145863A1 (en) * 2002-02-06 2003-08-07 Ultradent Products. Inc. Method for using denture reline material in conjunction with sport mouth guards
US20030180680A1 (en) * 2002-03-25 2003-09-25 Burgio Paul A. Dental impression tray with impression material retainer
US20090087812A1 (en) * 2007-10-02 2009-04-02 Ultradent Products, Inc. Self-customizable dental treatment trays

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5718577A (en) * 1996-03-15 1998-02-17 Minnesota Mining & Manufacturing Dental impression tray with chemiluminescent light source
US5772432A (en) * 1996-10-18 1998-06-30 Minnesota Mining & Manufacturing Co. Dental impression tray with improved adhesion to impression material
US20030145863A1 (en) * 2002-02-06 2003-08-07 Ultradent Products. Inc. Method for using denture reline material in conjunction with sport mouth guards
US20030180680A1 (en) * 2002-03-25 2003-09-25 Burgio Paul A. Dental impression tray with impression material retainer
US20090087812A1 (en) * 2007-10-02 2009-04-02 Ultradent Products, Inc. Self-customizable dental treatment trays

Also Published As

Publication number Publication date
WO2012034076A2 (en) 2012-03-15

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