WO2012024046A3 - Pentose fermentation by a recombinant microorganism - Google Patents

Pentose fermentation by a recombinant microorganism Download PDF

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Publication number
WO2012024046A3
WO2012024046A3 PCT/US2011/044441 US2011044441W WO2012024046A3 WO 2012024046 A3 WO2012024046 A3 WO 2012024046A3 US 2011044441 W US2011044441 W US 2011044441W WO 2012024046 A3 WO2012024046 A3 WO 2012024046A3
Authority
WO
WIPO (PCT)
Prior art keywords
recombinant microorganism
pentose fermentation
recombinant
xylose isomerase
pentose
Prior art date
Application number
PCT/US2011/044441
Other languages
French (fr)
Other versions
WO2012024046A2 (en
Inventor
Ezhilkani Subbian
Xiyun Zhang
Original Assignee
Codexis, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Codexis, Inc. filed Critical Codexis, Inc.
Publication of WO2012024046A2 publication Critical patent/WO2012024046A2/en
Publication of WO2012024046A3 publication Critical patent/WO2012024046A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y503/00—Intramolecular oxidoreductases (5.3)
    • C12Y503/01—Intramolecular oxidoreductases (5.3) interconverting aldoses and ketoses (5.3.1)
    • C12Y503/01005—Xylose isomerase (5.3.1.5)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)
    • C12N9/92—Glucose isomerase (5.3.1.5; 5.3.1.9; 5.3.1.18)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/06—Ethanol, i.e. non-beverage
    • C12P7/08—Ethanol, i.e. non-beverage produced as by-product or from waste or cellulosic material substrate
    • C12P7/10—Ethanol, i.e. non-beverage produced as by-product or from waste or cellulosic material substrate substrate containing cellulosic material
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Provided are recombinant nucleic acid constructs comprising a xylose isomerase polynucleotide, a recombinant fungal host cell comprising a recombinant xylose isomerase polynucleotide, and related methods.
PCT/US2011/044441 2010-08-20 2011-07-19 Pentose fermentation by a recombinant microorganism WO2012024046A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37544510P 2010-08-20 2010-08-20
US61/375,445 2010-08-20

Publications (2)

Publication Number Publication Date
WO2012024046A2 WO2012024046A2 (en) 2012-02-23
WO2012024046A3 true WO2012024046A3 (en) 2014-03-27

Family

ID=45605603

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2011/044441 WO2012024046A2 (en) 2010-08-20 2011-07-19 Pentose fermentation by a recombinant microorganism

Country Status (1)

Country Link
WO (1) WO2012024046A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8778652B2 (en) * 2011-06-30 2014-07-15 Codexis, Inc. Pentose fermentation by a recombinant microorganism
US9951326B2 (en) 2015-07-13 2018-04-24 MARA Renewables Corporation Enhancing microbial metabolism of C5 organic carbon

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080014620A1 (en) * 2002-01-23 2008-01-17 Op Den Camp Hubertus Johannes Fermentation of pentose sugars
WO2010074577A1 (en) * 2008-12-24 2010-07-01 Royal Nedalco B.V. Xylose isomerase genes and their use in fermentation of pentose sugars

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080014620A1 (en) * 2002-01-23 2008-01-17 Op Den Camp Hubertus Johannes Fermentation of pentose sugars
WO2010074577A1 (en) * 2008-12-24 2010-07-01 Royal Nedalco B.V. Xylose isomerase genes and their use in fermentation of pentose sugars

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE GENBANK 5 July 2005 (2005-07-05), JAILLON, O ET AL., retrieved from http://www.ncbi.nlm.nih.gov/nuccore/CR660550 accession no. R660550 *
DATABASE UNIPROT 15 December 2009 (2009-12-15), NUSBAUM, C. ET AL., retrieved from http://www.uniprot.org/uniproUDONA42.bct?version=1 accession no. ONA42 *
HAAS, B.J. ET AL.: "Genome sequence and analysis of the Irish potato famine pathogen . Phytophthora infestans.", NATURE., vol. 461, 17 September 2009 (2009-09-17), pages 393 - 398 *

Also Published As

Publication number Publication date
WO2012024046A2 (en) 2012-02-23

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