WO2012005873A2 - Ensemble applicateur d'antiseptique - Google Patents

Ensemble applicateur d'antiseptique Download PDF

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Publication number
WO2012005873A2
WO2012005873A2 PCT/US2011/040146 US2011040146W WO2012005873A2 WO 2012005873 A2 WO2012005873 A2 WO 2012005873A2 US 2011040146 W US2011040146 W US 2011040146W WO 2012005873 A2 WO2012005873 A2 WO 2012005873A2
Authority
WO
WIPO (PCT)
Prior art keywords
protective device
pocket
applicator assembly
ampoule
manufacturing
Prior art date
Application number
PCT/US2011/040146
Other languages
English (en)
Other versions
WO2012005873A3 (fr
Inventor
Manuel Guzman
James P. Mcdonald
Original Assignee
Carefusion 2200, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Carefusion 2200, Inc. filed Critical Carefusion 2200, Inc.
Priority to MX2013000194A priority Critical patent/MX2013000194A/es
Priority to CA2804004A priority patent/CA2804004C/fr
Priority to BR112012033728A priority patent/BR112012033728A2/pt
Priority to KR1020137002588A priority patent/KR101682474B1/ko
Priority to CN2011800326091A priority patent/CN103068436A/zh
Priority to ES11804009.6T priority patent/ES2627119T3/es
Priority to AU2011276773A priority patent/AU2011276773B9/en
Priority to RU2013103644/14A priority patent/RU2013103644A/ru
Priority to EP11804009.6A priority patent/EP2588183B1/fr
Publication of WO2012005873A2 publication Critical patent/WO2012005873A2/fr
Publication of WO2012005873A3 publication Critical patent/WO2012005873A3/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M35/00—Devices for applying media, e.g. remedies, on the human body
    • A61M35/003—Portable hand-held applicators having means for dispensing or spreading integral media
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
    • A61L2/18—Liquid substances or solutions comprising solids or dissolved gases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/26—Accessories or devices or components used for biocidal treatment

Definitions

  • the present disclosure relates to an antiseptic applicator assembly, method of manufacture thereof and method of use thereof, and more particularly, to an antiseptic applicator assembly including a body having an integral protective device, a closed, liquid- filled ampoule received in the body, and an applicator member secured to the body so that liquid flows through the protective device and the applicator member when the ampoule is fractured.
  • Antiseptic applicator assemblies for the preparation of a patient prior to surgery are known and common in the prior art.
  • Conventional applicators rely on various means of actuation to release a self-contained reservoir of antimicrobial solution for sterilization of the patient's skin.
  • a number of applicators rely on breaking an internally situated frangible container or ampoule through the application of a one-way directional force or a localized application of pressure.
  • the directional force is typically applied longitudinally to one end of the ampoule by a pushing motion designed to force the ampoule to break under a compressive stress, sometimes at a predetermined area of stress concentration.
  • a pressure may be applied to a localized section of the ampoule through a squeezing motion designed to crush a section of the frangible ampoule in order to release the antimicrobial solution contained therein.
  • Some examples of applicators using frangible ampoules in the manner discussed above include U.S. Pat. Nos. 3,757,782; 5,288,159; 5,308,180; 5,435,660: 5,445,462; 5,538,353 5,658,084; 5,690,958, 5,772,346; 5,791 ,801 ; 5,927,884; 6,371 ,675; and 6,916,133.
  • the conventional applicators have been developed to include shaped walls having inward projections that engage the periphery of the ampoule to maintain the ampoule within the cavity and to prevent untoward movement of shards of glass through an applicator member when fracturing of the ampoule is effected. Further, applicators have been developed with shaped walls presenting a region to be grasped and squeezed by the user which provide a fulcruming effect so that the user squeezes the shaped wall at a location that is not directly in contact with the ampoule.
  • the ampoule is fractured at a location that is spaced from the portion of the wall that is squeezed by the user, protecting the user from shards of the ampoule projecting through the wall.
  • liquid applicators represent an improvement over earlier conventional devices, there is a need to provide a liquid applicator that reduces or preferably eliminates the risk of the user being injured by shards of glass or glass particles penetrating the applicator member.
  • an applicator assembly includes a body defining a pocket, a closed ampoule received in the pocket, an integrated protective device attached to the body and enclosing the pocket, a lever projecting from the body, at least one tappet that bears against an external surface of the pocket and fractures the ampoule when the lever is pivoted, and an application member secured to
  • the applicator assembly may include a securing mechanism for securing the protective device to the
  • a method for manufacturing the applicator assembly includes rotating the protective device from an open position into a closed position to enclose the ampoule in the pocket before the 0 application member is attached to the body so that the fluid to be dispensed will flow through the protective device and contact the application member when the ampoule is fractured.
  • a method for manufacturing an applicator assembly may include using a molding apparatus to form a 5
  • body defining a pocket, releasing the body from the molding apparatus, placing a frangible ampoule into the pocket, folding a protective device laterally across the open side of the pocket, securing the protective device into a closed position, and securing the application member to the body to cover at least a portion of the protective device.
  • FIG. 1 is a front plan view of an antiseptic applicator, in accordance with certain aspects of the present invention.
  • FIG. 2 is a side plan view of an antiseptic applicator, in accordance with certain aspects of the present invention.
  • FIG. 3 is a perspective view of an exemplary antiseptic applicator, in accordance with certain aspects of the present invention.
  • FIG. 4 is a rear view of an antiseptic applicator, in accordance with certain aspects of the present invention.
  • FIG. 5 is a top view of an antiseptic applicator, in accordance with certain aspects of the present invention.
  • FIG. 6 is a perspective view of an exemplary antiseptic applicator, in accordance with certain aspects of the present invention.
  • FIG. 7 is a plan view of an exemplary antiseptic applicator mold assembly, in accordance with certain aspects of the present invention.
  • an antiseptic applicator assembly may be illustrated by describing components that are coupled, attached, and/or joined together.
  • the terms “coupled”, “attached”, and/or “joined” are used to indicate either a direct connection between two components or, where appropriate, an indirect connection to one another through intervening or intermediate components.
  • a component is referred to as being “directly coupled”, “directly attached”, and/or “directly joined” to another component, there are no intervening elements present.
  • Relative terms such as “lower” or “bottom” and “upper” or “top” may be used herein to describe one element's relationship to another element illustrated in the drawings. It will be understood that relative terms are intended to encompass different orientations of an antiseptic applicator assembly in addition to the orientation depicted in the drawings. By way of example, if an antiseptic applicator assembly in the drawings is turned over, elements described as being on the “bottom” side of the other elements would then be oriented on the “top” side of the other elements. The term “bottom” can therefore encompass both an orientation of “bottom” and “top” depending on the particular orientation of the apparatus.
  • an antiseptic applicator assembly may be illustrated with reference to one or more exemplary embodiments.
  • the term "exemplary” means “serving as an example, instance, or illustration,” and should not necessarily be construed as preferred or advantageous over other embodiments of an antiseptic applicator assembly disclosed herein.
  • Figs. 1 and 2 illustrate an antiseptic applicator assembly 1 in accordance with aspects of the present invention.
  • the applicator assembly is illustrated as broadly including a body 12 having an integral protective device 50, a closed, liquid-filled ampoule
  • the application member 16 may be formed from a porous material, such as a sponge, for example, or any suitable material that allows the controlled application of the contained solution from the ampoule 14 to a surface external to the applicator assembly 1 .
  • the material chosen may be porous with a particular soak rate, for example, or may be provided with structural features, including slits or apertures, to direct and control the flow rate of the solution through the application member 16.
  • the ampoule 14 may be filled with various liquids such as antiseptics or medicaments, chemical compositions, cleansing agents, cosmetics, or the like, and preferably an antimicrobial liquid or gel composition , such as a chlorhexadine gluconate solution, for antiseptic application to a patient prior to surgery.
  • the ampoule 14 is designed to withstand various heat and chemical sterilization techniques, which may be performed sequentially with a solution filling process, in accordance with techniques that are well known in the art.
  • the ampoule 14 is illustrated as an elongated cylinder, it will be appreciated that the principles of the present invention may also be applied to spherical or elongated polygonal ampoules.
  • the ampoule 14 is formed of glass, although other fracturable materials are within the scope of the present invention.
  • the wall of the glass ampoule 14 is of a thickness sufficient to contain the desired liquid during transport and storage, yet allow the ampoule to be fractured upon the application of sufficient localized pressure.
  • the body 12 which is preferably formed of a plastic material such as high density polyethylene or any suitable material exhibiting similar flexibility and integrity, includes an open-sided pocket 18 within which the ampoule may be received and may include a flange 20 protruding from the pocket 18 along the open side thereof.
  • the pocket 18 has a shape generally conforming to the shape of the ampoule, as shown in Figs. 1 and 2. Accordingly, the pocket 18 may be elongated and include a pair of laterally spaced side walls that are connected together by a U-shaped top wall.
  • the pocket 18 defines a longitudinal axis that is generally collinear with the central longitudinal axis of the ampoule and an axial plane which includes the pocket axis and is generally parallel to the flange 20.
  • a mounting ridge 21 may be provided to extend away from the body along a portion of a lower surface of the flange 20 surrounding the pocket 18. The mounting ridge 21 , if present, may provide a surface for affixing the application member to the body 12.
  • the body 12 also includes a pair of elongated gripping members 24, 26 projecting from the body 12 and having a wing-like configuration.
  • the members 24, 26 may run longitudinally along a length of the pocket and are each spaced from the pocket 18 on opposite sides thereof.
  • optional ribs 28 may be provided, which extend laterally outward to facilitate handling of the applicator.
  • each of the members 24, 26 may be provided with a relatively large, textured outer surface to prevent slippage from the user's hand during application, which may take the form of a series of steps 32.
  • the flange 20 may support the gripping members 24, 26 for pivoting movement relative to the pocket 18. Accordingly, the gripping members 24, 26 define levers that may be grasped by the user and pivoted toward one another against the pocket, and this pivoting movement is accommodated by the flexibility of the material forming the body.
  • the body 12 also includes structure for fracturing the ampoule.
  • the structure includes breaking tappets 36, 38 and optionally a retaining tappet 40, interposed between the gripping members 24, 26 and the pocket 18.
  • the breaking tappets 36, 38 interconnect the gripping member 24 and the pocket.
  • the tappets 36, 38, 40 are arranged so that when the gripping members 24, 26 are pivoted toward one another by the user, the tappets 36, 38, 40 deform the pocket inwardly at positions immediately adjacent the tappets to exert inward forces against the ampoule.
  • the textured outer surfaces of the gripping members 24, 26 present a gripping area which is significantly larger than the area of the tappets which deform the pocket 18 inwardly, thereby localizing the forces effected by squeezing the members 24, 26, and enhancing fracturing of the ampoule.
  • the configuration of the tappets causes the portion of the pocket extending from the axial plane to the flange to move inwardly at the tappets.
  • the inwardly moving pocket engages the outermost point of the ampoule to exert localized fracturing forces against the ampoule that are generally vertically aligned with its central axis.
  • the fracturing forces applied by the breaking tappets do not cause the ampoule to move toward or away from the open side of the pocket.
  • the optional retaining tappet causes a portion of the pocket extending from the flange to a location between the flange and axial plane to move inwardly in the region of the retaining tappet.
  • the inwardly moving pocket effected by the retaining tappet engages the ampoule at a point offset beneath the axial plane, thereby exerting a localized fracturing force against the ampoule which pushes the ampoule away from the open side of the pocket.
  • the configuration of the retaining tappet maintains the ampoule within the pocket when the gripping members are pivoted toward one another to fracture the ampoule so that the ampoule does not shift prior to experiencing the localized fracturing forces being applied thereon.
  • the optional retaining tappet may be centrally disposed along the length of the pocket.
  • the tappets 36, 38 are spaced axially from the retaining tappet 40 and from one another on opposite sides of the tappet 40.
  • the relative positioning of the tappets 36, 38, 40 concentrates the fracturing forces in a somewhat triangular pattern, enhancing the fracturing of the ampoule.
  • the principles of the present invention are equally applicable to various other structure for fracturing the ampoule.
  • the body also includes the integrated protective device 50, which may be formed as a plate, for example, and hinged to the body 12 via the optional flange 20 along a longitudinal edge.
  • the protective device 50 may be formed to have a shape that fully encloses the pocket 8 when the protective device 50 is folded down into a closed position (e.g., see Fig. 6).
  • the protective device 50 may include a securing mechanism 52, such as an extended tab that snaps into a corresponding slot in the body 12 or an adhesive applied around the perimeter of the protective device 50, for example, for securing the protective device 50 in a closed position after the ampoule 14 is placed into the pocket 18.
  • a pattern of through-holes 54 may be formed in the protective device 50 to allow passage of fluid, while preventing passage of glass shards or particles, from the internal pocket 18 to the application member.
  • the through-holes 54 may be formed to be .05 inches in diameter, for example, and provided in an equally spaced manner over the area of the protective device 50 to permit even distribution of the fluid from the pocket 18 into the application member.
  • the protective device 50 may be provided with structural features, including slits or apertures, to direct and control the flow rate of the solution from the pocket 18 into the application member.
  • the pocket 18 may be formed so as to be deep enough to secure the ampoule 14 internally to the body 12 so as to avoid or minimize contact between the ampoule 14 and the protective device 50. As such, additional pressure points on the ampoule 14 from external forces applied against the protective device 50 during transportation and/or assembly, for example, may be avoided, protecting the ampoule 14 from premature fracture.
  • a mold may be used to form the applicator body 12 with the integrated features discussed above, in accordance with known injection molding techniques, for example.
  • a first mold part 60 which is the stationary section, is formed to hold the body 12 by way of the pocket 18.
  • a second mold part 62 is formed to hold an outer side of the protective device 50 and the gripping member 26.
  • a third mold part 64 is formed to hold the inner side of the protective device 50 and the gripping member 24.
  • the second mold part 62 moves laterally away from the formed body 12.
  • the third mold part 64 moves vertically away from the applicator assembly to first disengage from the internal pocket 18. Then the third mold part 64 moves laterally away from the formed body 12.
  • the formed applicator body 12 may then be easily removed from the molding apparatus with the assistance of optional ejector pins, for example, and transferred as appropriate, either manually or automatically, for final assembly of the applicator assembly.
  • the efficiency and cost- effectiveness of the manufacture and assembly of the applicator assembly may be enhanced.
  • an enhanced protective barrier may be provided without an increase in the number of associate parts required during the assembly process of the applicator assembly.
  • the applicator assembly may be assembled by placing the body into an equipment fixture, for example, which may be a conveyor assembly. The ampoule is then placed into the pocket, either manually or automatically, and the protective device is folded laterally across the pocket so that the locking mechanism secures the protective device in a closed position while enclosing the ampoule.
  • a welding beam 56 may be provided on the exterior surface of the protective device 50 so that when the protective device 50 is in the closed position, the welding beam 56 and the mounting ridge 21 form a continuous mounting surface along the lower surface of the body 12.
  • the application member may be secured to the body over the open side of the protective device so the liquid flows from the pocket, through the protective device, and through the application member when the ampoule is fractured.
  • a laminate material such as a polyester fabric that is resistant to stretching in one direction, referred to as the machine direction of the fabric, may be provided on the mounting side of the application member.
  • the application member may be secured to the body of the applicator by welding the fabric laminate material to the body, optionally via the flange and/or the mounting ridge, if present, and the welding beam 56, using an ultrasonic welding operation, for example.
  • the polyester material of the laminate provides suitable welding material that melts together with the material of the body to secure the application member in place over the protective device enclosing the pocket containing the ampoule.
  • Other suitable securing expedients could be employed in place of the ultrasonic welding operation.
  • the application member could be secured in place by an adhesive, or by stitching the element in place.
  • the applicator is designed to be grasped by the user so that the gripping members are held between the thumb or palm and fingers of one hand of the user.
  • the members preferably include ribs and textured regions to facilitate handling of the applicator and to inhibit slippage from the user's hand.
  • the ampoule is fractured by the user squeezing or pivoting the gripping members toward one another. The pivoting movement of the members is transferred by the tappets to the pocket to deform the pocket inwardly and exert discrete localized fracturing forces against the ampoule.
  • the gripping members provide a lever action that gains mechanical advantage as the members are pivoted towards one another about the flange. Accordingly, if the user has limited gripping strength, or if the wall of the ampoule is exceptionally thick, the members ensure fracturing of the ampoule.
  • the resulting forces fracture the ampoule releasing the liquid contained therein.
  • the optional retaining tappet forces the ampoule away from the open side of the pocket during fracturing which generally directs shards of glass away from the application member.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Packages (AREA)
  • Coating Apparatus (AREA)
  • Packaging Frangible Articles (AREA)

Abstract

L'invention porte sur un ensemble applicateur comprenant un corps définissant une poche, une ampoule fermée reçue dans la poche, un dispositif de protection intégré fixé au corps et renfermant la poche, un levier faisant saillie à partir du corps, au moins un poussoir qui s'appuie contre une surface externe de la poche et casse l'ampoule lorsque le levier pivote, et un élément d'application fixé au corps, une partie intérieure de la poche étant placée en communication fluidique avec l'élément d'application au moyen de trous traversants disposés dans le dispositif de protection intégré. Un procédé de fabrication de l'ensemble applicateur comprend la rotation du dispositif de protection d'une position ouverte dans une position fermée de façon à renfermer l'ampoule dans la poche avant que l'élément d'application ne soit fixé au corps, de telle sorte que le fluide à administrer s'écoulera à travers le dispositif de protection et viendra en contact avec l'élément d'application lorsque l'ampoule sera cassée.
PCT/US2011/040146 2010-06-30 2011-06-13 Ensemble applicateur d'antiseptique WO2012005873A2 (fr)

Priority Applications (9)

Application Number Priority Date Filing Date Title
MX2013000194A MX2013000194A (es) 2010-06-30 2011-06-13 Ensamble aplicador antiseptico.
CA2804004A CA2804004C (fr) 2010-06-30 2011-06-13 Ensemble applicateur d'antiseptique
BR112012033728A BR112012033728A2 (pt) 2010-06-30 2011-06-13 sistema de aplicação e métodos para sua fabricação.
KR1020137002588A KR101682474B1 (ko) 2010-06-30 2011-06-13 소독용 기구 어셈블리
CN2011800326091A CN103068436A (zh) 2010-06-30 2011-06-13 抗菌涂药器组件
ES11804009.6T ES2627119T3 (es) 2010-06-30 2011-06-13 Conjunto de aplicador antiséptico
AU2011276773A AU2011276773B9 (en) 2010-06-30 2011-06-13 Antiseptic applicator assembly
RU2013103644/14A RU2013103644A (ru) 2010-06-30 2011-06-13 Устройство аппликатора антисептика
EP11804009.6A EP2588183B1 (fr) 2010-06-30 2011-06-13 Ensemble applicateur d'antiseptique

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12/827,631 US8864399B2 (en) 2010-06-30 2010-06-30 Antiseptic applicator assembly
US12/827,631 2010-06-30

Publications (2)

Publication Number Publication Date
WO2012005873A2 true WO2012005873A2 (fr) 2012-01-12
WO2012005873A3 WO2012005873A3 (fr) 2012-04-12

Family

ID=45399819

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2011/040146 WO2012005873A2 (fr) 2010-06-30 2011-06-13 Ensemble applicateur d'antiseptique

Country Status (11)

Country Link
US (1) US8864399B2 (fr)
EP (1) EP2588183B1 (fr)
KR (1) KR101682474B1 (fr)
CN (2) CN107261310A (fr)
AU (1) AU2011276773B9 (fr)
BR (1) BR112012033728A2 (fr)
CA (1) CA2804004C (fr)
ES (1) ES2627119T3 (fr)
MX (1) MX2013000194A (fr)
RU (1) RU2013103644A (fr)
WO (1) WO2012005873A2 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9867973B2 (en) 2013-06-17 2018-01-16 Medline Industries, Inc. Skin antiseptic applicator and methods of making and using the same
US9724437B2 (en) * 2013-08-08 2017-08-08 Lernapharm (Loris) Inc. Heat sterilization techniques for chlorhexidine based antiseptic formulations
US9757551B2 (en) 2013-10-04 2017-09-12 Carefusion 2200, Inc. Antiseptic applicator
WO2016179679A1 (fr) 2015-05-13 2016-11-17 Razmik Margoosian Applicateurs de distribution de liquide médical et procédés de fabrication
US10669065B2 (en) 2016-08-22 2020-06-02 James Alexander Corporation Dispenser and process
US10946624B2 (en) * 2017-06-29 2021-03-16 Patrick Mcclain Glass repair kit and method
US11247837B1 (en) 2017-08-21 2022-02-15 James Alexander Corporation Dispenser actuator assembly
US11857747B1 (en) 2018-10-11 2024-01-02 James Alexander Corporation Dispenser actuator assembly
US11241709B1 (en) 2018-10-11 2022-02-08 James Alexander Corporation Dispenser actuator assembly
US11542136B1 (en) 2018-10-11 2023-01-03 James Alexander Corporation Dispenser actuator assembly

Family Cites Families (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2253287A (en) 1939-07-14 1941-08-19 Walter W Pitann Suture and method of packaging and sterilizing the same
US2361413A (en) 1940-06-28 1944-10-31 Font Juan Luis Pujoly Method and apparatus for making ampoules containing compressed gas
FR1391729A (fr) 1963-10-01 1965-03-12 Procédé et appareillages de traitement thermique en continu de produits placés enrécipients étanches
US3531300A (en) 1964-11-17 1970-09-29 Pillsbury Co Process for heat treating food sealed within flexible containers
US3355240A (en) 1966-04-15 1967-11-28 Schwartzman Gilbert Applicator with bonded or snap fitted cover
US3466131A (en) 1967-09-07 1969-09-09 Becton Dickinson Co Dispensing applicator package
US3598517A (en) 1969-05-12 1971-08-10 American Sterilizer Co Automatic control for balanced pressure process
US3754368A (en) 1969-11-04 1973-08-28 Moore Perk Corp Sterile packaging method
US3725003A (en) 1969-11-04 1973-04-03 Moore Perk Corp Method of sterile packaging
US3768916A (en) 1971-12-01 1973-10-30 Medical Supply Co Sponge with encapsulated liquid
US3774609A (en) 1972-01-31 1973-11-27 G Schwartzman Surgical preparatory applicator
US3757782A (en) 1972-06-05 1973-09-11 Vivian C Aiken Fluid pressurizable swab applicator for medicament, antiseptic or the like
NL173913C (nl) 1973-07-10 1984-04-02 Stork Amsterdam Installatie voor het thermisch behandelen van in houders verpakte waren.
US3998559A (en) 1975-07-28 1976-12-21 Earl Hoyt Disposable fountain applicator
US4088444A (en) 1976-06-09 1978-05-09 Baxter Travenol Laboratories, Inc. Process and apparatus for sterilizing containers
US4183684A (en) 1977-11-29 1980-01-15 Marion Health & Safety, Inc. Fluid dispensing unit
KR840002646A (ko) 1981-12-09 1984-07-16 고니시 진우에몬 구급용 반창고
US4475835A (en) 1982-09-21 1984-10-09 Miles Laboratories, Inc. Device for cleaning soil from oven surfaces
EP0160051B1 (fr) 1983-10-24 1992-01-08 Lockley Services Pty. Ltd. Composition biocide a pouvoir moussant
DE3545116A1 (de) 1985-05-17 1986-11-20 Transaktor KB International, Göteborg Flasche fuer wassernotverpflegung und verfahren zur herstellung einer flasche mit wassernotverpflegung
FR2584952B1 (fr) 1985-07-17 1987-11-20 Kores Sa Dispositif pour l'application d'une quantite predeterminee d'un liquide sur une surface
US4963045A (en) 1987-05-15 1990-10-16 The Willcox Family Trust Dispenser-applicator for spreading substances
US4878775A (en) 1987-10-28 1989-11-07 Minnesota Mining And Manufacturing Company Liquid transfer device
US5025123A (en) 1988-10-07 1991-06-18 Continental Can Company, Inc. Apparatus and method for sealing a lid onto a container
US4956962A (en) 1989-07-14 1990-09-18 Bryan Food, Inc. Method of making reclosable sealed package
US5103836A (en) 1990-02-28 1992-04-14 Epitope, Inc. Oral collection device and kit for immunoassay
US5147337A (en) 1990-05-07 1992-09-15 Clifford Plone Medicament dispenser
US4989733A (en) 1990-05-21 1991-02-05 Marc Patry Ready-to-use medical trays
US5205110C1 (en) 1990-12-12 2001-05-15 Dec Int Servo motor operated indexing motion packaging machine and method
US5117613A (en) 1991-04-11 1992-06-02 Tocco, Inc. Induction heating and package sealing system and method
US5308180A (en) 1991-12-09 1994-05-03 Minnesota Mining And Manufacturing Company Liquid applicator with metering insert
US5288159A (en) 1992-12-04 1994-02-22 Minnesota Mining And Manufacturing Company Liquid applicator with frangible ampoule and support
US5445462A (en) 1993-08-03 1995-08-29 Medi-Flex Hospital Products, Inc. Liquid applicator
US5443150A (en) 1993-09-23 1995-08-22 Rapidpak, Inc. Apparatus for advancing preformed containers
US5538353A (en) 1995-08-25 1996-07-23 Medi-Flex Hospital Products, Inc. Liquid applicator
US5775826A (en) 1996-05-29 1998-07-07 Siebe North, Inc. Safety fluid dispensing system
USD386849S (en) 1996-07-23 1997-11-25 Medi-Flex Hospital Products, Inc. Liquid applicator
US5791801A (en) 1996-08-30 1998-08-11 Siebe North, Inc. Liquid applicator
US5690958A (en) * 1996-09-30 1997-11-25 Medi-Flex Hospital Products, Inc. Unit dose chlorhexadine gluconate(CHG) applicator having extended CHG shelf life
US5772346A (en) 1997-04-22 1998-06-30 Medi-Flex Hospital Products, Inc. Liquid applicator with structural insert
US5752363A (en) 1997-04-22 1998-05-19 Edwards; William R. Method and apparatus for manufacturing liquid dispensers
USD396911S (en) 1997-06-02 1998-08-11 Medi-Flex Hospital Products, Inc. Liquid applicator body
US5927884A (en) 1998-01-28 1999-07-27 Kao; Yu-Chien Disposable perfume stick
EP1152683A4 (fr) * 1998-12-23 2002-04-03 Thomas G Frazier Applicateur de liquides avec dispositif activateur a bague coulissante
US20020076258A1 (en) * 2000-12-20 2002-06-20 Crosby Cynthia T. Skin disinfectant applicator
US6371675B1 (en) 2000-12-20 2002-04-16 Becton, Dickinson And Company Skin disinfectant applicator
CN1166535C (zh) * 2001-02-23 2004-09-15 康那香企业股份有限公司 湿巾容器的易充填装置
US6991394B2 (en) * 2003-01-10 2006-01-31 Medi-Flex, Inc. Liquid applicator with a mechanism for fracturing multiple ampoules
US6729786B1 (en) * 2003-03-14 2004-05-04 Mediflex Hospital Products, Inc. Liquid applicator for coloring a liquid
US6916133B2 (en) 2003-06-02 2005-07-12 Becton, Dickinson And Company Patient preparatory applicator with a back plug activator
NZ552953A (en) * 2004-08-09 2011-02-25 Tyco Healthcare Medical skin applicator apparatus with an internal fluid container, a penetrating member and actuated by an externally protruding member
US7540681B2 (en) * 2004-10-04 2009-06-02 3M Innovative Properties Company Surgical prep solution applicator
US8083425B2 (en) * 2005-05-26 2011-12-27 Biomed Packaging Systems Inc. Dispensing applicator for fluids
AR056792A1 (es) * 2005-11-12 2007-10-24 Unilever Nv Dispensador capilar
US7524125B2 (en) * 2007-06-06 2009-04-28 Lambert Hubert L Liquid soap dispensing and scrubbing tool
CN201304108Y (zh) * 2008-12-10 2009-09-09 张宪香 一种多瓶粉剂药溶解快速操作装置

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of EP2588183A4 *

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CA2804004A1 (fr) 2012-01-12
AU2011276773B9 (en) 2014-12-18
KR20130058725A (ko) 2013-06-04
AU2011276773B2 (en) 2014-11-20
EP2588183B1 (fr) 2017-03-15
US20120003029A1 (en) 2012-01-05
MX2013000194A (es) 2013-06-28
ES2627119T3 (es) 2017-07-26
AU2011276773A1 (en) 2013-02-07
RU2013103644A (ru) 2014-08-10
EP2588183A4 (fr) 2014-01-15
EP2588183A2 (fr) 2013-05-08
US8864399B2 (en) 2014-10-21
WO2012005873A3 (fr) 2012-04-12
CA2804004C (fr) 2016-10-25
CN103068436A (zh) 2013-04-24
BR112012033728A2 (pt) 2016-11-22
CN107261310A (zh) 2017-10-20
KR101682474B1 (ko) 2016-12-12

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