WO2011139250A3 - Water dispersible formulation comprising betahistine - Google Patents

Water dispersible formulation comprising betahistine Download PDF

Info

Publication number
WO2011139250A3
WO2011139250A3 PCT/TR2011/000123 TR2011000123W WO2011139250A3 WO 2011139250 A3 WO2011139250 A3 WO 2011139250A3 TR 2011000123 W TR2011000123 W TR 2011000123W WO 2011139250 A3 WO2011139250 A3 WO 2011139250A3
Authority
WO
WIPO (PCT)
Prior art keywords
betahistine
water dispersible
dispersible formulation
formulation
active agent
Prior art date
Application number
PCT/TR2011/000123
Other languages
French (fr)
Other versions
WO2011139250A2 (en
Inventor
Mahmut Bilgic
Original Assignee
Mahmut Bilgic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mahmut Bilgic filed Critical Mahmut Bilgic
Publication of WO2011139250A2 publication Critical patent/WO2011139250A2/en
Publication of WO2011139250A3 publication Critical patent/WO2011139250A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4402—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007—Effervescent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention relates to new water dispersible pharmaceutical formulations comprising betahistine as the active agent.
PCT/TR2011/000123 2010-05-04 2011-05-02 Water dispersible formulation WO2011139250A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
TR201003540 2010-05-04
TR2010/03540 2010-05-04

Publications (2)

Publication Number Publication Date
WO2011139250A2 WO2011139250A2 (en) 2011-11-10
WO2011139250A3 true WO2011139250A3 (en) 2012-03-01

Family

ID=44120871

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/TR2011/000123 WO2011139250A2 (en) 2010-05-04 2011-05-02 Water dispersible formulation

Country Status (1)

Country Link
WO (1) WO2011139250A2 (en)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0397025A1 (en) * 1989-05-08 1990-11-14 PRODOTTI FORMENTI S.r.l. [2-(2-pyridyl)ethyl]-methylamine salts
GB2280604A (en) * 1993-07-02 1995-02-08 Resource Medical Limited Tablet formulation of betahistine and selegiline
US20050074489A1 (en) * 2003-10-01 2005-04-07 Pediamed Pharmaceuticals, Inc. Effervescent and effervescent-dispersion compositions for medicaments and methods of use thereof
EP2314296A1 (en) * 2009-10-22 2011-04-27 Abdi Ibrahim Ilac Sanayi Ve Ticaret Anonim Sirketi Orally Disintegrating Tablets of Betahistine

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2397840B1 (en) 1977-07-22 1981-03-20 Cherqui Jean

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0397025A1 (en) * 1989-05-08 1990-11-14 PRODOTTI FORMENTI S.r.l. [2-(2-pyridyl)ethyl]-methylamine salts
GB2280604A (en) * 1993-07-02 1995-02-08 Resource Medical Limited Tablet formulation of betahistine and selegiline
US20050074489A1 (en) * 2003-10-01 2005-04-07 Pediamed Pharmaceuticals, Inc. Effervescent and effervescent-dispersion compositions for medicaments and methods of use thereof
EP2314296A1 (en) * 2009-10-22 2011-04-27 Abdi Ibrahim Ilac Sanayi Ve Ticaret Anonim Sirketi Orally Disintegrating Tablets of Betahistine

Also Published As

Publication number Publication date
WO2011139250A2 (en) 2011-11-10

Similar Documents

Publication Publication Date Title
EP3216448B8 (en) Parasiticidal oral veterinary compositions comprising systemically-acting active agents, methods and uses thereof
WO2012021715A3 (en) Stable formulations of linaclotide
WO2011130615A3 (en) Preparation of lacosamide
WO2011093824A3 (en) Effervescent formulations comprising cefaclor
IL224288A (en) Derivatives of substituted pyrazolamide, pharmaceutical compositions comprising the same and uses thereof
WO2010000877A3 (en) Formulation with irritation reducing action comprising bisabolol and [6]-paradol
WO2010021607A3 (en) Pharmaceutical formulation
IT1404931B1 (en) OPHTHALMIC COMPOSITIONS FOR THE ADMINISTRATION OF LIPO-SOLUBLE ACTIVE PRINCIPLES.
WO2011017502A3 (en) Linaclotide-containing formulations for oral administration
PL2768936T3 (en) Formulations, their use as or for the manufacture of dishwashing compositions, and manufacture
WO2012048176A3 (en) Attachment and retention formulations for biologically active organic compounds
WO2013134534A3 (en) Solid state forms of cabazitaxel and processes for preparation thereof
WO2012137227A3 (en) Solid forms of antiretroviral compounds and anti-oxidative acids, processes for preparation and pharmaceutical compositions thereof
WO2011002422A3 (en) Solubility enhancing pharmaceutical formulation
WO2011142731A3 (en) Formulations comprising a third generation cephalosporin and clavulanic acid
HK1208188A1 (en) Formulations for the delivery of active ingredients
ZA201306643B (en) Formulation comprising phenylaminopyrimidine derivatives as active agent
WO2012054695A8 (en) Antimicrobial amphiphiles and methods for their use
WO2011139249A3 (en) Pharmaceutical composition comprising cefdinir
SI2590620T1 (en) Stable aqueous formulations comprising poorly water soluble active ingredients
WO2014056851A3 (en) Flavor and fragrance formulation (i)
WO2012060790A3 (en) Water dispersible cefpodoxime proxetil formulations
WO2011093831A3 (en) Effervescent formulations comprising cefprozil as active agent
WO2012093973A3 (en) Compositions in the form of tablets comprising acarbose
WO2012026907A3 (en) Cefpodoxime proxetil formulations

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 11721589

Country of ref document: EP

Kind code of ref document: A2

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 11721589

Country of ref document: EP

Kind code of ref document: A2