WO2011118953A3 - Composition for the prevention or treatment of obesity or lipid related metabolic deseases - Google Patents

Composition for the prevention or treatment of obesity or lipid related metabolic deseases Download PDF

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Publication number
WO2011118953A3
WO2011118953A3 PCT/KR2011/001945 KR2011001945W WO2011118953A3 WO 2011118953 A3 WO2011118953 A3 WO 2011118953A3 KR 2011001945 W KR2011001945 W KR 2011001945W WO 2011118953 A3 WO2011118953 A3 WO 2011118953A3
Authority
WO
WIPO (PCT)
Prior art keywords
obesity
prevention
composition
related metabolic
xylem
Prior art date
Application number
PCT/KR2011/001945
Other languages
French (fr)
Other versions
WO2011118953A2 (en
Inventor
Soon-Hoe Kim
Mi-Won Son
Tae-Ho Lee
Yong-Sung Sohn
Sang-Zin Choi
Nam-Joon Baek
Jin-Seok Jeong
Sang-Jin Lee
Seul-Ki Lee
Original Assignee
Dong-A Pharm.Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dong-A Pharm.Co., Ltd. filed Critical Dong-A Pharm.Co., Ltd.
Publication of WO2011118953A2 publication Critical patent/WO2011118953A2/en
Publication of WO2011118953A3 publication Critical patent/WO2011118953A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/13—Coniferophyta (gymnosperms)
    • A61K36/14—Cupressaceae (Cypress family), e.g. juniper or cypress
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Child & Adolescent Psychology (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

The present invention provides a pharmaceutical composition for the prevention or treatment of obesity or a lipid-related metabolic disease and a food for the amelioration or prevention of obesity or a lipid-related metabolic disease, containing an extract of at least one xylem selected from Thuja orientalis Linne xylem, Juniperus mexicana xylem and Thujopsis dolabrata xylem or (-)-thujopsene, as an active ingredient. The extract and (-)-thujopsene contained in the composition or food of the present invention exhibit significant body fat- and body weight-reducing effects and lowers plasma levels of glucose, GOT, GPT, LDL-cholesterol, and LDL/VLDL cholesterol. Accordingly, the composition and food of the present invention are effective for the treatment, amelioration or prevention of lipid-related metabolic diseases or obesity.
PCT/KR2011/001945 2010-03-25 2011-03-22 Composition for the prevention or treatment of obesity or lipid related metabolic deseases WO2011118953A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2010-0026863 2010-03-25
KR1020100026863A KR101138565B1 (en) 2010-03-25 2010-03-25 Composition for the prevention or treatment of obesity or lipid related metabolic deseases

Publications (2)

Publication Number Publication Date
WO2011118953A2 WO2011118953A2 (en) 2011-09-29
WO2011118953A3 true WO2011118953A3 (en) 2012-01-12

Family

ID=44673742

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2011/001945 WO2011118953A2 (en) 2010-03-25 2011-03-22 Composition for the prevention or treatment of obesity or lipid related metabolic deseases

Country Status (2)

Country Link
KR (1) KR101138565B1 (en)
WO (1) WO2011118953A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101716801B1 (en) * 2015-04-15 2017-03-15 서울대학교산학협력단 Food composition against metabolic disease or pharmaceutical composition against metabolic disease containing 5-(3',4'-Dihydroxyphenyl)-gamma-valerolactone and 5-(3',4'-Dihydroxyphenyl)-gamma-valerolactone derivatives

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006213657A (en) * 2005-02-04 2006-08-17 Kaneka Corp HUMAN beta3-ADRENALIN RECEPTOR AGONIST AGENT
JP2006225297A (en) * 2005-02-16 2006-08-31 Fancl Corp Agent for treating/preventing obesity, hyperlipemia and arteriosclerotic disease
KR20070008230A (en) * 2005-07-13 2007-01-17 한국생명공학연구원 Composition for the prevention and treatment of obesity and type 2 diabetes comprising a juniperus chinensis extract or cedrol
KR20080085358A (en) * 2007-03-19 2008-09-24 한국과학기술연구원 Composition comprising the extracts, fractions and the isolated compounds of thuja orientalis for prevention or treatment of diabetic complications
KR20090011590A (en) * 2007-07-26 2009-02-02 김세창 Hypoglycaemic activity of ethanolic extracts and hypolipidemic activity of aqueous extracts from chinese juniper berries
KR100905419B1 (en) * 2008-09-11 2009-07-02 연세대학교 산학협력단 Uses of sesquiterpene derivatives
KR100911623B1 (en) * 2008-05-19 2009-08-12 연세대학교 산학협력단 Fractions for preventing or treating obesity, hypercholesterolemia or diabetes

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006213657A (en) * 2005-02-04 2006-08-17 Kaneka Corp HUMAN beta3-ADRENALIN RECEPTOR AGONIST AGENT
JP2006225297A (en) * 2005-02-16 2006-08-31 Fancl Corp Agent for treating/preventing obesity, hyperlipemia and arteriosclerotic disease
KR20070008230A (en) * 2005-07-13 2007-01-17 한국생명공학연구원 Composition for the prevention and treatment of obesity and type 2 diabetes comprising a juniperus chinensis extract or cedrol
KR20080085358A (en) * 2007-03-19 2008-09-24 한국과학기술연구원 Composition comprising the extracts, fractions and the isolated compounds of thuja orientalis for prevention or treatment of diabetic complications
KR20090011590A (en) * 2007-07-26 2009-02-02 김세창 Hypoglycaemic activity of ethanolic extracts and hypolipidemic activity of aqueous extracts from chinese juniper berries
KR100911623B1 (en) * 2008-05-19 2009-08-12 연세대학교 산학협력단 Fractions for preventing or treating obesity, hypercholesterolemia or diabetes
KR100905419B1 (en) * 2008-09-11 2009-07-02 연세대학교 산학협력단 Uses of sesquiterpene derivatives

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
S. K. DUBEY ET AL.: "Anti diabetic activity of Thuja occidentalis Linn.", RESEARCH JOURNAL OF PHARMACY AND TECHNOLOGY, vol. 1, no. 4, October 2008 (2008-10-01), pages 362 - 365 *

Also Published As

Publication number Publication date
KR101138565B1 (en) 2012-05-10
WO2011118953A2 (en) 2011-09-29
KR20110107625A (en) 2011-10-04

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