WO2011116091A1 - Dispenser - Google Patents

Dispenser Download PDF

Info

Publication number
WO2011116091A1
WO2011116091A1 PCT/US2011/028662 US2011028662W WO2011116091A1 WO 2011116091 A1 WO2011116091 A1 WO 2011116091A1 US 2011028662 W US2011028662 W US 2011028662W WO 2011116091 A1 WO2011116091 A1 WO 2011116091A1
Authority
WO
WIPO (PCT)
Prior art keywords
medicament
dispenser
carrier
aperture
medicament carrier
Prior art date
Application number
PCT/US2011/028662
Other languages
English (en)
French (fr)
Inventor
Tony Antunes
Emilie Beskar
David Hemmerlin
Aurele Hurtis
Francis John Lovell
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of WO2011116091A1 publication Critical patent/WO2011116091A1/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D83/00—Containers or packages with special means for dispensing contents
    • B65D83/04—Containers or packages with special means for dispensing contents for dispensing annular, disc-shaped, or spherical or like small articles, e.g. tablets or pills
    • B65D83/0445—Containers or packages with special means for dispensing contents for dispensing annular, disc-shaped, or spherical or like small articles, e.g. tablets or pills all the articles being stored in individual compartments
    • B65D83/0463—Containers or packages with special means for dispensing contents for dispensing annular, disc-shaped, or spherical or like small articles, e.g. tablets or pills all the articles being stored in individual compartments formed in a band or a blisterweb, inserted in a dispensing device or container
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/03—Containers specially adapted for medical or pharmaceutical purposes for pills or tablets
    • A61J1/035—Blister-type containers

Definitions

  • Medicaments can be supplied in many types of packaging from which a user must remove or release the medicament before it can be used/taken.
  • MS Multiple Sclerosis
  • the dispenser of the present invention is particularly intended for use with medicament comprising at least one compound which is a sphingosine 1-phosphate (SIP) receptor modulators or agonists.
  • SIP receptor modulators or agonists are compounds which signal as agonists at one or more sphingosinel-phosphate receptors, e.g. S1P1 to S1P5.
  • Agonist binding to a SIP receptor may e.g. result in dissociation of intracellular heterotrimeric G- proteins into Ga-GTP and G y-GTP, and/or increased phosphorylation of the agonist-occupied receptor and activation of downstream signalling pathways/kinases .
  • a medicament 8 released from the blister pack 4 passes through the associated inlet aperture 32 and enters the collecting conduit 118. However, the medicament cannot reach the dispensing apertures 16 in the second members due to the end walls 40 of the first member 120.
  • the medicament is an orally delivered medicament in the form of a tablet or capsule, that is suitable for treatment of inflammatory or autoimmune diseases or disorders, or diseases affecting hands dexterity or causing visual impairment.
  • the medicament comprises at least one of fingolimod in free form, in a pharmaceutically acceptable salt form or fingolimod- phosphate.
  • end walls 40 of the first member 120 could each include one or more apertures aperture through which a medicament 8 could pass so that the dispenser 101 could dispense in the open configuration.
  • Figures 9 and 10 shows a cross section through a further embodiment of a dispenser 201 in a closed and open configuration respectively. Many features function in the same way as in the dispenser 1 and will be given the same reference numeral. Where a feature is different, but functions in similar way the feature will be given a similar reference numeral incremented by 200.

Landscapes

  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
PCT/US2011/028662 2010-03-17 2011-03-16 Dispenser WO2011116091A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US31464510P 2010-03-17 2010-03-17
US61/314,645 2010-03-17

Publications (1)

Publication Number Publication Date
WO2011116091A1 true WO2011116091A1 (en) 2011-09-22

Family

ID=44080378

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2011/028662 WO2011116091A1 (en) 2010-03-17 2011-03-16 Dispenser

Country Status (2)

Country Link
AR (1) AR080766A1 (es)
WO (1) WO2011116091A1 (es)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11629124B2 (en) 2017-03-09 2023-04-18 Novartis Ag Solid forms comprising an oxime ether compound, compositions and methods of use thereof
US12070059B2 (en) 2020-09-04 2024-08-27 Nicoventures Trading Limited Child-resistant container for tobacco-containing products

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2478591A1 (fr) * 1980-03-20 1981-09-25 Seprosy Emballage de securite, notamment pour medicaments sous forme de pilules, gelules, comprimes et analogues
DE3838144A1 (de) * 1988-11-10 1990-05-17 Hans Lobermeier Verpackung fuer klein dimensionierte waren, wie tabletten, pillen, bonbons und dergleichen
EP0559238A1 (de) 1985-09-27 1993-09-08 Hoechst Aktiengesellschaft Cyancrotonsäureamidverbindung als Arzneimittel mit immunmodulierenden Eigenschaften
WO2000030622A2 (de) 1998-11-19 2000-06-02 Fumapharm Ag Verwendung von dialkylfumaraten zur behandlung von host-versus-graft reaktionen und von autoimmunerkrankungen
EP1073639A1 (en) 1998-04-27 2001-02-07 Active Biotech AB Quinoline derivatives
WO2004103306A2 (en) 2003-05-19 2004-12-02 Irm Llc Immunosuppressant compounds and compositions
WO2010033649A1 (en) * 2008-09-18 2010-03-25 Novartis Ag Dispenser

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2478591A1 (fr) * 1980-03-20 1981-09-25 Seprosy Emballage de securite, notamment pour medicaments sous forme de pilules, gelules, comprimes et analogues
EP0559238A1 (de) 1985-09-27 1993-09-08 Hoechst Aktiengesellschaft Cyancrotonsäureamidverbindung als Arzneimittel mit immunmodulierenden Eigenschaften
DE3838144A1 (de) * 1988-11-10 1990-05-17 Hans Lobermeier Verpackung fuer klein dimensionierte waren, wie tabletten, pillen, bonbons und dergleichen
EP1073639A1 (en) 1998-04-27 2001-02-07 Active Biotech AB Quinoline derivatives
WO2000030622A2 (de) 1998-11-19 2000-06-02 Fumapharm Ag Verwendung von dialkylfumaraten zur behandlung von host-versus-graft reaktionen und von autoimmunerkrankungen
WO2004103306A2 (en) 2003-05-19 2004-12-02 Irm Llc Immunosuppressant compounds and compositions
WO2010033649A1 (en) * 2008-09-18 2010-03-25 Novartis Ag Dispenser

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11629124B2 (en) 2017-03-09 2023-04-18 Novartis Ag Solid forms comprising an oxime ether compound, compositions and methods of use thereof
US12070059B2 (en) 2020-09-04 2024-08-27 Nicoventures Trading Limited Child-resistant container for tobacco-containing products

Also Published As

Publication number Publication date
AR080766A1 (es) 2012-05-09

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