WO2011115416A3 - Fraction de sedum sarmentosum pour décomposer l'alcool et soulager la gueule de bois - Google Patents

Fraction de sedum sarmentosum pour décomposer l'alcool et soulager la gueule de bois Download PDF

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Publication number
WO2011115416A3
WO2011115416A3 PCT/KR2011/001815 KR2011001815W WO2011115416A3 WO 2011115416 A3 WO2011115416 A3 WO 2011115416A3 KR 2011001815 W KR2011001815 W KR 2011001815W WO 2011115416 A3 WO2011115416 A3 WO 2011115416A3
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WO
WIPO (PCT)
Prior art keywords
alcohol
fraction
sedum sarmentosum
providing
breaking down
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PCT/KR2011/001815
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English (en)
Korean (ko)
Other versions
WO2011115416A2 (fr
Inventor
성창근
모은경
김승미
양선아
이청하
조현호
김현호
이승엽
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(주)대덕바이오
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Publication of WO2011115416A2 publication Critical patent/WO2011115416A2/fr
Publication of WO2011115416A3 publication Critical patent/WO2011115416A3/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/41—Crassulaceae (Stonecrop family)
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2200/00—Function of food ingredients
    • A23V2200/30—Foods, ingredients or supplements having a functional effect on health
    • A23V2200/334—Foods, ingredients or supplements having a functional effect on health treating the effects of consuming alcohol, narcotics or other addictive behavior, e.g. treating hangover or reducing blood alcohol levels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mycology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Botany (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Medical Informatics (AREA)
  • Addiction (AREA)
  • Microbiology (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Psychiatry (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La présente invention porte sur une fraction de Sedum sarmentosum qui possède une excellente propriété de décomposition de l'alcool et de soulagement de la gueule de bois. Une fraction d'acétate d'éthyle de l'extrait alcoolique de Sedum sarmentosum facilite les activités de l'ADH et de l'ALDH, qui sont des enzymes du foie associées au métabolisme de l'alcool, et donc soulage les symptômes de la gueule de bois tels que la soif, une faiblesse générale, la fatigue ou autres, qui sont les effets secondaires provoqués par l'absorption d'alcool. L'activation de l'ADH et de l'ALDH permet à l'éthanol d'être rapidement décomposé en acide acétique, qui est le produit final du métabolisme de l'alcool, réduisant ainsi les lésions hépatiques provoquées par l'absorption d'alcool et améliore la résistance à un grand nombre de maladies provoquées par l'absorption d'alcool.
PCT/KR2011/001815 2010-03-15 2011-03-15 Fraction de sedum sarmentosum pour décomposer l'alcool et soulager la gueule de bois WO2011115416A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020100022893A KR100976241B1 (ko) 2010-03-15 2010-03-15 알코올분해 및 숙취해소용 돌나물 분획물
KR10-2010-0022893 2010-03-15

Publications (2)

Publication Number Publication Date
WO2011115416A2 WO2011115416A2 (fr) 2011-09-22
WO2011115416A3 true WO2011115416A3 (fr) 2012-01-12

Family

ID=42759687

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2011/001815 WO2011115416A2 (fr) 2010-03-15 2011-03-15 Fraction de sedum sarmentosum pour décomposer l'alcool et soulager la gueule de bois

Country Status (2)

Country Link
KR (1) KR100976241B1 (fr)
WO (1) WO2011115416A2 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106344597A (zh) * 2016-08-18 2017-01-25 滨州医学院 垂盆草苷在制备预防或治疗急性肺损伤和肺纤维化的药物中的应用
CN111297935B (zh) * 2019-12-20 2021-10-01 河南省医药科学研究院 一种垂盆草提取物及其制备方法和应用

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102161442B1 (ko) 2013-10-10 2020-10-05 주식회사 젬백스앤카엘 알코올 대사 조절용 조성물
KR102106757B1 (ko) 2013-11-29 2020-05-06 주식회사 젬백스앤카엘 난소 동결 보존용 펩티드 및 이를 포함하는 조성물
KR102230958B1 (ko) 2019-06-05 2021-03-23 한국 한의학 연구원 수분초를 유효성분으로 포함하는 뼈 성장 촉진용 조성물

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20070021585A (ko) * 2005-08-19 2007-02-23 한불화장품주식회사 돌나물 추출물을 주요 활성성분으로 함유하는 피부외용제조성물
JP2008266272A (ja) * 2007-04-25 2008-11-06 Univ Kinki 垂盆草から得られる肝保護剤、該肝保護剤を含有する医薬又は食品、及び垂盆草から得られる新規メガスチグマン化合物。

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20070021585A (ko) * 2005-08-19 2007-02-23 한불화장품주식회사 돌나물 추출물을 주요 활성성분으로 함유하는 피부외용제조성물
JP2008266272A (ja) * 2007-04-25 2008-11-06 Univ Kinki 垂盆草から得られる肝保護剤、該肝保護剤を含有する医薬又は食品、及び垂盆草から得られる新規メガスチグマン化合物。

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
B.-G. HEO ET AL.: "Antioxidant activity and cytotoxicity of methanol extracts from aerial parts of Korean salad plants", BIOFACTORS, vol. 30, 2007, pages 79 - 89 *
JAE SUE CHOI ET AL.: "Studies on the active principles of wild vegetables on biot ransformation of drug", KOREAN JOURNAL OF PHARMACOGNOSY, vol. 20, no. 2, 1989, pages 117 - 122 *
K. NINOMIYA ET AL.: "Bioactive constituents from chinese natural medicines. XXIII. Absolute structures of new megastigmane glycosides, sedumosides A4, A5, A6, H and I, and hepatoprotective megastigmanes from Sedum sarmentosum", CHEMICAL & PHARMACEUTICAL BULLETINE, vol. 55, no. 8, 2007, pages 1185 - 1191 *
SEO, DONG JIN ET AL.: "The studies on search of antifibrotic effect by several herbs extract in rat liver tissue", KOREAN JOURNAL OF ORIENTAL PREVENTIVE MEDICAL SOCIETY, vol. 5, no. 2, 2001, pages 116 - 133 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106344597A (zh) * 2016-08-18 2017-01-25 滨州医学院 垂盆草苷在制备预防或治疗急性肺损伤和肺纤维化的药物中的应用
CN111297935B (zh) * 2019-12-20 2021-10-01 河南省医药科学研究院 一种垂盆草提取物及其制备方法和应用

Also Published As

Publication number Publication date
WO2011115416A2 (fr) 2011-09-22
KR100976241B1 (ko) 2010-08-17

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