WO2011112774A1 - Abdominal treatment systems, delivery devices, and methods - Google Patents

Abdominal treatment systems, delivery devices, and methods Download PDF

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Publication number
WO2011112774A1
WO2011112774A1 PCT/US2011/027835 US2011027835W WO2011112774A1 WO 2011112774 A1 WO2011112774 A1 WO 2011112774A1 US 2011027835 W US2011027835 W US 2011027835W WO 2011112774 A1 WO2011112774 A1 WO 2011112774A1
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WO
WIPO (PCT)
Prior art keywords
foam spacer
liquid
layers
treatment device
pressure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2011/027835
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English (en)
French (fr)
Inventor
Tyler Simmons
Alexander Sammons
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KCI Licensing Inc
Original Assignee
KCI Licensing Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44560640&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=WO2011112774(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority to CA2789002A priority Critical patent/CA2789002C/en
Priority to CN201180011563.5A priority patent/CN102811750B/zh
Priority to AU2011224324A priority patent/AU2011224324B2/en
Priority to EP11710939.7A priority patent/EP2544730B2/en
Priority to JP2012557235A priority patent/JP5844751B2/ja
Application filed by KCI Licensing Inc filed Critical KCI Licensing Inc
Priority to EP16157204.5A priority patent/EP3042671B1/en
Priority to EP20167306.8A priority patent/EP3695858A1/en
Publication of WO2011112774A1 publication Critical patent/WO2011112774A1/en
Anticipated expiration legal-status Critical
Priority to AU2016201800A priority patent/AU2016201800B2/en
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F13/05—Bandages or dressings; Absorbent pads specially adapted for use with sub-pressure or over-pressure therapy, wound drainage or wound irrigation, e.g. for use with negative-pressure wound therapy [NPWT]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/90—Negative pressure wound therapy devices, i.e. devices for applying suction to a wound to promote healing, e.g. including a vacuum dressing
    • A61M1/91—Suction aspects of the dressing
    • A61M1/916—Suction aspects of the dressing specially adapted for deep wounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/90—Negative pressure wound therapy devices, i.e. devices for applying suction to a wound to promote healing, e.g. including a vacuum dressing
    • A61M1/92—Negative pressure wound therapy devices, i.e. devices for applying suction to a wound to promote healing, e.g. including a vacuum dressing with liquid supply means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/0007—Special media to be introduced, removed or treated introduced into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00—Anatomical parts of the body
    • A61M2210/10—Trunk
    • A61M2210/1021—Abdominal cavity

Definitions

  • the present disclosure relates generally to medical treatment systems, and more particularly, to abdominal treatment systems, delivery devices, and methods for treating an abdominal cavity using reduced pressure.
  • reduced pressure may be used for, among other things, reduced-pressure therapy to encourage granulation at a tissue site or for draining fluids at a tissue site.
  • reduced-pressure therapy to encourage granulation at a tissue site or for draining fluids at a tissue site.
  • "or” does not require mutual exclusivity. Both reduced-pressure therapy and drainage with reduced pressure often involve manifolding, or distributing, reduced pressure to the tissue site.
  • the plurality of liquid-impermeable layers has a coextensive area Ai and the liquid-impermeable layers are fenestrated.
  • the foam spacer has a plan-view area A 2 , and A 2 is less than 80 % of Ai (i.e., A 2 ⁇ 0.8Ai).
  • the foam spacer is configured and located such that, under reduced pressure, a target fluid removal zone experiences reduced-pressure vectors over an angle theta ( ⁇ ) that is 360 degrees for a majority of locations in the target fluid removal zone.
  • a system for treating an abdominal cavity with reduced pressure includes an abdominal treatment device for distributing reduced pressure to a tissue site and a reduced-pressure source.
  • the reduced- pressure source is fluidly coupled to the abdominal treatment device.
  • the abdominal treatment device includes a plurality of liquid-impermeable layers that are proximate to one another and a foam spacer disposed between at least two layers of the plurality of liquid- impermeable layers.
  • the plurality of liquid-impermeable layers has a coextensive area Ai and is fenestrated.
  • the foam spacer has a plan-view area A 2 , and A2 is less than 80 % of Ai (i.e., A 2 ⁇ 0.8Ai).
  • the foam spacer is configured such that, under reduced pressure, a target fluid removal zone experiences reduced-pressure vectors over an angle theta ( ⁇ ) that is 360 degrees for a majority of locations in the target fluid removal zone.
  • a method of manufacturing an abdominal treatment device includes the steps of providing a plurality of liquid-impermeable layers that are fenestrated and disposing a foam spacer between at least two layers of the plurality of liquid-impermeable layers.
  • the plurality of liquid-impermeable layers has a coextensive area ⁇ .
  • the foam spacer disposed between at least two layers of the plurality of liquid-impermeable layers has a plan-view area A 2 , and A 2 is less than 80 % of Ai (i.e., A 2 ⁇ 0.8Ai).
  • the foam spacer is configured and located such that, under reduced pressure, a target fluid removal zone experiences reduced-pressure vectors over an angle theta ( ⁇ ) that is 360 degrees for a majority of locations in the target fluid removal zone.
  • a method of treating a tissue site in an abdominal cavity includes the steps of: opening the abdominal cavity to form an open cavity; deploying within the abdominal cavity an abdominal treatment delivery device; deploying a reduced-pressure connector subsystem; and deploying a sealing member to form a fluid seal over the open cavity.
  • the method further includes fluidly coupling the reduced-pressure connector subsystem to a reduced-pressure source and activating the reduced-pressure source.
  • the abdominal treatment device includes a plurality of liquid-impermeable layers that are proximate to one another and a foam spacer disposed between at least two layers of the plurality of liquid-impermeable layers.
  • the plurality of liquid-impermeable layers has a coextensive area Ai and is fenestrated.
  • the foam spacer has a plan-view area A 2 , and A 2 is less than 80 % of Ai (i.e., A 2 ⁇ 0.8Ai).
  • the foam spacer is configured and located such that, under reduced pressure, a target fluid removal zone experiences reduced-pressure vectors over an angle theta ( ⁇ ) that is 360 degrees for a majority of locations in the target fluid removal zone.
  • FIGURE 1 is a schematic diagram with a portion in cross section of an illustrative system for treating an abdominal cavity
  • FIGURE 2 is a schematic, plan view of an illustrative abdominal treatment device
  • FIGURE 3 is a schematic, cross-sectional view of a portion of the illustrative abdominal treatment device of FIGURE 2 taken along line 3-3;
  • FIGURE 4A is a schematic plan view of a portion of an abdominal treatment device
  • FIGURE 4B is a schematic cross section of a portion of the abdominal treatment device of FIGURE 4A taken along line 4B-4B;
  • FIGURE 5 is another schematic, plan view of another illustrative abdominal treatment device
  • FIGURE 6 is a schematic, plan view of another illustrative abdominal treatment device
  • FIGURE 7 is a schematic, exploded perspective view of another illustrative abdominal treatment device.
  • FIGURE 8 is a schematic, plan view of the illustrative abdominal treatment device of FIGURE 6 shown with an additional feature.
  • the system 100 includes an abdominal treatment device 104.
  • the system 100 and the abdominal treatment device 104 are for treating a tissue site 106 of a patient.
  • the tissue site 106 may be the bodily tissue of any human, animal, or other organism.
  • the tissue site 106 includes tissue in a body cavity, and in particular the abdominal cavity 102.
  • the tissue site 106 includes the abdominal contents 108 or tissue that is proximate the abdominal cavity 102.
  • Treatment of the tissue site 106 may include removal of fluids, e.g., ascites, protection of the abdominal cavity, or reduced-pressure therapy.
  • the abdominal treatment device 104 is disposed within the abdominal cavity 102 of the patient to treat the tissue site 106.
  • the abdominal treatment device 104 is supported by the abdominal contents 108.
  • the abdominal contents 108 include a surface on which the abdominal treatment device 104 is positioned.
  • a portion 110 of the abdominal treatment device 104 may be positioned in or proximate to a first paracolic gutter 112, and another portion 114 may be placed in or proximate to a second paracolic gutter 1 16.
  • the abdominal treatment device 104 is formed with a plurality of liquid- impermeable layers 1 17, e.g., a first liquid-impermeable layer 1 18 and a second liquid- impermeable layer 120.
  • FIGURE 1 is a schematic drawing and is not to scale.
  • the plurality of liquid-impermeable layers 117, e.g., layers 1 18, 120, is formed with fenestrations 122, 124, respectively.
  • "Liquid impermeable" with respect to "liquid-impermeable layers” means that the layers are formed with a liquid-impermeable material.
  • the layer may be liquid permeable when fenestrated, but nonetheless is referred to as a liquid- impermeable layer.
  • the fenestrations 122, 124 may take any shape, e.g., circular apertures, rectangular openings, polygons, or any other shape.
  • the fenestrations 122, 124 are presented in this illustrative embodiment as slits, or linear cuts.
  • a foam spacer 125 is disposed between at least two layers of the plurality of liquid-impermeable layers, e.g., the first liquid-impermeable layer 118 and the second liquid-impermeable layer 120.
  • the abdominal treatment device 104 has a first side 105 and a second, tissue- facing side 107.
  • the abdominal treatment device 104 is typically symmetrical such that the sides 105, 107 are same. Reference to different sides of the abdominal treatment device 104 is made for explanation purposes.
  • a manifold 126 or manifold pad, distributes reduced pressure to the abdominal treatment device 104.
  • a sealing member 128 provides a fluid seal over the abdominal cavity 102.
  • One or more skin closure devices may be placed on a patient's epidermis 130.
  • a reduced-pressure connector subsystem 132 may be used to fluidly connect the abdominal treatment device 104 to a reduced-pressure conduit 134.
  • the reduced-pressure connector subsystem 132 may include a reduced-pressure connector 136, or interface, and the manifold 126.
  • the reduced-pressure connector subsystem 132 may be an in situ connector (not shown) on the abdominal treatment device 104 or any other device for supplying reduced pressure to the abdominal treatment device 104.
  • the reduced-pressure conduit 134 is fluidly coupled to a reduced-pressure source 138.
  • reduced pressure is delivered to the abdominal treatment device 104 through the manifold 126 which receives reduced pressure through the reduced-pressure connector 136, which is coupled to the reduced-pressure delivery conduit 134.
  • the reduced-pressure source 138 delivers reduced pressure to the reduced- pressure delivery conduit 134.
  • the reduced pressure may be applied to the tissue site 106 to help promote removal of ascites, exudates, or other fluids from the tissue site 106. In some instances, reduced pressure may be applied to stimulate the growth of additional tissue. In some instances, only fluid removal may be desired.
  • reduced pressure generally refers to a pressure less than the ambient pressure at a tissue site that is being subjected to treatment. In most cases, this reduced pressure will be less than the atmospheric pressure at which the patient is located. Alternatively, the reduced pressure may be less than a hydrostatic pressure at the tissue site. Reduced pressure may initially generate fluid flow in the manifold 126, the reduced-pressure delivery conduit 134, and proximate the tissue site 106.
  • the manifold 126 is shown adjacent to the abdominal treatment device 104.
  • the manifold 126 may take many forms.
  • the term "manifold” as used herein generally refers to a substance or structure that is provided to assist in applying reduced pressure to, delivering fluids to, or removing fluids from the tissue site 106 or other location.
  • the manifold 126 typically includes a plurality of flow channels or pathways that distribute the fluids provided to and removed around the manifold 126. In one illustrative embodiment, the flow channels or pathways are interconnected to improve distribution of fluids provided or removed from the tissue site 106.
  • the manifold 126 may be a biocompatible material that is capable of being placed in contact with tissue site.
  • manifold 126 may include, without limitation, devices that have structural elements arranged to form flow channels, cellular foam, such as open-cell foam, porous tissue collections, liquids, gels and foams that include or cure to include flow channels.
  • the manifold 126 may be porous and may be made from foam, gauze, felted mat, or any other material suited to a particular biological application.
  • the manifold 126 is a porous foam and includes a plurality of interconnected cells or pores that act as flow channels.
  • the porous foam may be a polyurethane, open-cell, reticulated foam, such as a GranuFoam® material manufactured by Kinetic Concepts, Incorporated of San Antonio, Texas. Other embodiments might include "closed cells.”
  • the manifold 126 may also be used to distribute fluids, such as medications, antibacterials, growth factors, and various solutions to the tissue site 106 or to another location.
  • Other layers may be included in or on the manifold 126, such as absorptive materials, wicking materials, hydrophobic materials, and hydrophilic materials.
  • the foam spacer 125 in the abdominal treatment device 104 may be made from any of the same materials as the manifold 126.
  • the foam spacer 125 may be a polyurethane, open-cell, reticulated foam, such as a GranuFoam® material.
  • the sealing member 128 is placed over the abdominal cavity 102 and provides a fluid seal.
  • fluid seal or “seal,” means a seal adequate to maintain reduced pressure at a desired site given the particular reduced-pressure source 138 or subsystem involved.
  • the sealing member 128 may be a cover that is used to secure the manifold 126 on a portion of the abdominal treatment device 104.
  • the sealing member 128 may be impermeable or semi-permeable.
  • the sealing member 128 is capable of maintaining reduced pressure at the tissue site 106 after installation of the sealing member 128 over the abdominal cavity 102 and particularly an abdominal cavity opening 140.
  • the sealing member 128 may be a flexible over-drape or film formed from a silicone-based compound, acrylic, hydrogel or hydrogel-forming material, or any other biocompatible material that includes the
  • impermeability or permeability characteristics as desired for applying reduced pressure to the tissue site 106.
  • the sealing member 128 may further include an attachment device 142 to secure the sealing member 128 to the patient's epidermis 130.
  • the attachment device 142 may take many forms.
  • the attachment device may be an adhesive layer 144 that may be positioned along a perimeter, the entirety of, or any portion of the sealing member 128 to provide, directly or indirectly, the fluid seal with the patient's epidermis 130.
  • the adhesive layer 144 may also be pre-applied to the sealing member 128 and covered with a releasable backing, or member (not shown), that is removed at the time of application.
  • the reduced-pressure connector 136 may be, as one example, a port or connector, which permits the passage of fluid from the manifold 126 to the reduced-pressure delivery conduit 134 and vice versa. For example, fluid collected from the tissue site 106 using the manifold 126 and the abdominal treatment device 104 may enter the reduced- pressure delivery conduit 134 via the reduced-pressure connector 136. In another
  • the system 100 may omit the reduced-pressure connector 136 and the reduced- pressure delivery conduit 134 may be inserted directly into the sealing member 128 and into the manifold 126.
  • the reduced-pressure delivery conduit 134 may be a medical conduit or tubing or any other device for transporting a reduced pressure and fluid.
  • the reduced-pressure delivery conduit 134 may be a multi-lumen member.
  • the reduced- pressure delivery conduit 134 is a two-lumen conduit with one lumen for reduced pressure and liquid transport and one lumen for communicating pressure to a pressure sensor.
  • Reduced pressure is supplied to the reduced-pressure delivery conduit 134 by the reduced-pressure source 138.
  • a wide range of reduced pressures may be supplied by the reduced-pressure source 138.
  • the pressure may be in the range -50 to - 300 mm Hg and in another embodiment, in the range of -100 mm Hg to -200 mm Hg.
  • the pressure may be, for example, -100, -1 10, -120, -125, -130, -140, -150, -160, -170, -180, -190, or -200 mm Hg.
  • the reduced-pressure source 138 includes preset selectors for -100 mm Hg, -125 mm Hg, and -150 mm Hg.
  • the reduced-pressure source 138 may also include a number of alarms, such as a blockage alarm, a leakage alarm, or a battery-low alarm.
  • the reduced-pressure source 138 could be a portable source, wall source, or other unit for abdominal cavities.
  • the reduced-pressure source 138 may selectively deliver a constant pressure, varied pressure (patterned or random), intermittent pressure, or continuous pressure.
  • the fluid removed from the cavity through the reduced-pressure delivery conduit 134 could be as much as 5L or more per day depending on the circumstances.
  • a canister or fluid reservoir for receiving removed fluids may be associated with the reduced-pressure source 138.
  • a number of different devices may be added to a portion of the reduced-pressure delivery conduit 134.
  • the device 146 may be a fluid reservoir, or canister collection member, a pressure-feedback device, a volume detection system, a blood detection system, an infection detection system, a filter, a flow monitoring system, a temperature monitoring system, or other device. Multiple devices 146 may be included. Some of these devices, e.g., the fluid collection member, may be formed integrally with the reduced-pressure source 138.
  • the abdominal treatment device 104 is flexible and easily positioned within the abdominal cavity. At the same time, the abdominal treatment device 104 is adapted to avoid blockage at discrete locations on the abdominal treatment device 104 by having fluid flow over a large range of directions. In order to facilitate flexibility, the abdominal treatment device 104 may be formed with the foam spacer 125 smaller than the liquid-impermeable layers 1 17. [0034]
  • the abdominal treatment device 104 includes the plurality of liquid- impermeable layers 1 17, e.g., the first liquid-impermeable layer 1 18 and the second liquid- impermeable layer 120.
  • the micro-channel 168 space is formed between adjacent layers of the plurality of liquid-impermeable layers 117.
  • Additional layers may be included in the plurality of liquid-impermeable layers 117.
  • the plurality of liquid-impermeable layers 117 is formed with fenestrations, e.g., fenestrations 122, 124, and the layers of the plurality of liquid- impermeable layers 1 17 are placed proximate to one another to form a substantially flat member having a co-extensive area Ai.
  • the coextensive area Ai is the plan view area (before insertion) of where the layers of the plurality of liquid-impermeable layers 117 that are adjacent to the foam spacer 125 are co-extensive with one another.
  • the foam spacer 125 is disposed between at least two layers of the plurality of liquid-impermeable layers 117.
  • the plurality of liquid-impermeable layers 117 may be formed from the same materials as the sealing member 128.
  • each of the liquid-impermeable layers 117 may be of a thickness in the range of 50 to 120 microns and in another non-limiting embodiment may be approximately 80 microns.
  • the foam spacer 125 has a plan-view area A 2 , e.g., the area shown in plan view, that is less than the coextensive area Ai of the plurality of liquid-impermeable layers 117.
  • the plan- view area A 2 is less than the coextensive area A 2 of the plurality of liquid- impermeable layers 117 at least in part to enhance flexibility.
  • the plan-view area A 2 is less than 80 percent (80%) of the coextensive area Ai of the plurality of liquid-impermeable layers 117, i.e. A 2 ⁇ O.8A 1 .
  • the plan-view area A 2 may be less of a percentage of Ai, e.g., A 2 ⁇ 0.7Ai, A 2 ⁇ 0.6A A 2 ⁇ 0.5A b A 2 ⁇ 0.4A b A 2 ⁇ 0.3 A A 2 ⁇ 0.2A b A 2 ⁇ 0.1 A h etc.
  • a plurality of bonds 160 may be used to couple at least two layers of the plurality of liquid-impermeable layers 117. Any pattern or random bonds may be used for the plurality of bonds 160.
  • the bonds may be formed using any known technique, including without limitation, welding (e.g., ultrasonic or RF welding), bonding, adhesives, cements, or other bonding technique or apparatus.
  • the plurality of bonds 160 may include spacer bonds 162 that may be around or surround edges 164 of the foam spacer 125 as shown in plan view.
  • the spacer bonds 162 may be a stitch bond as shown in FIGURE 2 or a solid bond as shown in FIGURE 5.
  • the spacer bonds 162 help secure the foam spacer 125 in a fixed position relative to the plurality of liquid-impermeable layers 117.
  • the fenestrations e.g., fenestrations 122, 124, allow fluids to enter the space between the plurality of liquid- impermeable layers 1 17.
  • the fluids that enter the fenestrations 122, 124 move directly or indirectly towards a reduced-pressure source.
  • a reduced pressure may be, and typically is, applied to a center portion 166 of the abdominal treatment device 104 or elsewhere to cause fluid flow through the fenestrations 122, 124 and within the foam spacer 125 or micro-channels 168 (FIG.
  • the foam spacer 125 communicates reduced pressure within the plurality of liquid-impermeable layers 117 and often will be a dominant source of reduced-pressure.
  • the reduced pressure at various locations may be represented by pressure vectors, e.g., reduced-pressure vectors 156 (FIG. 2).
  • abdominal treatment device 104 While flexibility is desired for the abdominal treatment device 104, blockage avoidance is also desired. If an abdominal device 104 only had a center portion 166, a point in the micro-channel 168, or between liquid impermeable layers, would experience reduced pressure moving fluids in substantially one direction, or over a limited angle depending on its distance from the center portion 166. If that unidirectional path becomes blocked, the flow in a particular area may largely stop.
  • the present embodiment of the abdominal treatment device 104 delivers reduced pressure over a large angle, e.g., 270 - 360 degrees, for a given point. Typically, reduced pressure is experienced in all directions (360 degrees).
  • the foam spacer 125 provides the strongest source of reduced pressure within the micro-channels 168 and influences the flow directions.
  • a cylindrical analytical control volume 158 which is a control volume for analyzing pressure at a location in the micro- channel 168.
  • the control volume 158 experiences reduced pressure over 360 degrees.
  • the abdominal treatment device 104 may have all the analytical control volumes, e.g., analytical control volume 158, within a treatment area, or target fluid removal zone, experiencing 360 degrees of reduced pressure.
  • the angle over which the reduced pressure acts on a given analytical control volume, e.g., analytical control volume 158 is defined as angle theta ( ⁇ ).
  • 270 degrees of reduced pressure may be defined as a target fluid removal zone.
  • the area may experience 270, 280, 290, 300, 310, 320, 330, 340, 350, or 360 degrees of reduced pressure.
  • the target fluid removal zone is generally defined as the area bound substantially by an outer peripheral edge of the foam spacer 125 making allowances for any discontinuities.
  • the target fluid removal zone exists on the portion of the abdominal treatment device 104 that is inboard from a peripheral edge 150 by a distance 152.
  • the target fluid removal zone is from a peripheral edge 167 of the foam spacer 125 (or from the outer edge of a concentric circle 154) and inward.
  • the target fluid removal zone may have portions in which the analytical control volumes would have an angle theta ( ⁇ ) less than 360 degrees, e.g., 270 degrees, but preferably the majority, i.e., >50%, of locations analyzed will have 360 degrees of reduced pressure acting upon them.
  • the target flow zone may be defined as having more than 70 percent (70%) of the locations experiencing reduced pressure in 360 degrees.
  • the foam spacer 125 may be formed with a plurality of windows or window openings, such as where cylindrical analytical control volume 158 is shown.
  • FIGURES 4A and 4B a portion of an abdominal treatment device 104 is presented.
  • the portion shows portions of a foam spacer 125 under a first liquid- impermeable layer 118 having fenestrations 127.
  • the first liquid-impermeable layer 118 is bonded with bonds 160 to a second liquid-impermeable layer 120 with the foam spacer 125 therebetween.
  • a window 129 is formed by the foam spacer 125 in this portion of target fluid removal zone. Because the foam spacer 125 of the window 129 provides the main delivery of reduced pressure, an analytical control volume 158 experiences reduced pressure vectors 158 over angle theta of 360 degrees.
  • the reduced pressure in a given direction will be related to the distance from the analytical control volume 158 to the foam spacer 125 in a given direction.
  • a first reduced-pressure vector 159 and a second reduced-pressure vector 161 are the greatest because they are at locations closest to the foam spacer 125.
  • Third and fourth reduced-pressure vectors 163 and 165 are the least because they are the farthest from the foam spacer 125 in a given direction.
  • the foam spacer 125 may take numerous possible shapes.
  • the shape and size of the foam spacer 125 are typically selected to promote flexibility of the abdominal treatment device 104, i.e., to make the abdominal treatment device 104 compliant.
  • the flexibility typically helps place the abdominal treatment device 104 or a portion of the abdominal treatment device 104 in difficult-to-reach locations, such as the paracolic gutters 1 12 and 1 16, and helps remove the abdominal treatment device 104 in certain situations.
  • the abdominal treatment device 104 may be applied in some situations through an open abdomen with a directly connecting reduced-pressure delivery conduit 134, the abdominal cavity opening 140 closed, and then later the abdominal treatment device 104 may be removed through a surgical incision, e.g., an incision in the range of 5 centimeters to 40 centimeters— or any sub-range thereof.
  • the shape of the foam spacer 125 may be selected to promote a range of reduced-pressure vectors 156 in a target flow zone or to direct flow.
  • the foam spacer 125 is formed as a plurality of arced members, e.g., concentric circles or elliptical members, 170 that are interconnected by members 172.
  • the target treatment zone may experience 360 degrees of reduced pressure.
  • FIGURE 5 presents another illustrative shape.
  • the foam spacer 125 of the abdominal treatment device 104 includes mirrored c-shaped members that are interconnected.
  • the foam spacer 125 is formed with spacer bonds 162 that are one or more solid bonds.
  • analytical control volumes such as analytical control volume 158
  • in the target flow zone experience reduced-pressure vectors 156 that may be less than 360 degrees but greater than 270 degrees.
  • Other points e.g., interior point 174, may experience 360 degrees of reduced-pressure vectors 156.
  • the target flow zone for this embodiment is inboard of the outer peripheral edge 167 of the foam spacer 125.
  • the target flow zone may be defined as having more than 70 percent (70%) of the locations experiencing reduced pressure in 360 degrees.
  • FIGURE 6 presents a foam spacer 125 formed as a plurality of interconnected, annular circles.
  • analytical control volumes e.g., first analytical control volume 158 and second analytical control volumes 174
  • the spacer bonds 162 are shown as a stitch bond in this example.
  • FIGURES 7 and 8 another illustrative embodiment of an abdominal treatment device 104 is presented, but in this embodiment, control of the direction of the reduced pressure is desired.
  • the foam spacer 125 is formed as a star with a plurality of spaced leg members 178. Longitudinal bonds 182 have been added to direct fluid flow in a particular direction. Fluids attracted by this embodiment of the abdominal treatment device 104 primarily have flow along the foam spacer 125 and along flow channels 184 formed by the longitudinal bonds 182.
  • the foam spacer 125 is disposed between the first liquid-impermeable layer 118 and second liquid-impermeable layer 120 of the plurality of liquid-impermeable layers 117.
  • a plurality of bonds 160 including spacer bonds 162, are formed.
  • the spacer bonds 162 around the periphery may be excluded to leave an open intake space between the layers 1 18, 120 at the periphery.
  • the flow channels 180 are formed by placing the first longitudinal bonds 182 and the second longitudinal bonds 182 at desired locations.
  • the longitudinal bonds 182 and 184 may be formed radially outward from the center portion 166.
  • the longitudinal bonds 182, 184 may begin outboard of the center portion 166 as shown or may go all the way to the center portion 166.
  • Flow channels 180 may be used where increased or directed reduced pressure is more important than guarding against blockage.
  • Analytical control volume 186 shows the reduced pressure vectors may be oriented mainly toward the center portion 166.
  • the abdominal cavity 102 is opened and the abdominal treatment device 104 is deployed within the abdominal cavity 102.
  • the reduced pressure connector subsystem 132 may be fluidly coupled to the abdominal treatment device 104.
  • the reduced pressure connector subsystem 132 may be fluidly coupled to the reduced-pressure source 138 and the reduced-pressure source 138 activated.
  • the abdominal treatment device 104 may be removed through the open abdomen or later through a surgical incision.
  • the abdominal treatment device 104 may be manufactured, according to one illustrative embodiment, by providing the plurality of liquid-impermeable layers 117 that are fenestrated; stacking the plurality of liquid-impermeable layers 117; and disposing a foam spacer 125 between at least two layers of the plurality of liquid-impermeable layers 1 17.
  • the plurality of liquid-impermeable layers 117 has a coextensive area Ai.
  • the foam spacer 125 disposed between at least two layers of the plurality of liquid-impermeable layers 117 has a plan-view area A 2 .
  • a 2 is less than 80 % of Ai (i.e., A 2 ⁇ 0.8Ai).
  • the foam spacer 125 is configured and positioned such that, under reduced pressure, a target fluid removal zone experiences reduced-pressure vectors over an angle theta ( ⁇ ) that is greater than 90 degrees.

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  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Vascular Medicine (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
PCT/US2011/027835 2010-03-11 2011-03-10 Abdominal treatment systems, delivery devices, and methods Ceased WO2011112774A1 (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
EP20167306.8A EP3695858A1 (en) 2010-03-11 2011-03-10 Abdominal treatment systems, delivery devices, and methods
CN201180011563.5A CN102811750B (zh) 2010-03-11 2011-03-10 腹腔治疗系统、递送装置以及方法
AU2011224324A AU2011224324B2 (en) 2010-03-11 2011-03-10 Abdominal treatment systems, delivery devices, and methods
EP11710939.7A EP2544730B2 (en) 2010-03-11 2011-03-10 Abdominal treatment systems, delivery devices, and methods
JP2012557235A JP5844751B2 (ja) 2010-03-11 2011-03-10 腹部治療システム、送達装置、および方法
CA2789002A CA2789002C (en) 2010-03-11 2011-03-10 Abdominal treatment systems, delivery devices, and methods
EP16157204.5A EP3042671B1 (en) 2010-03-11 2011-03-10 Abdominal treatment systems, delivery devices, and methods
AU2016201800A AU2016201800B2 (en) 2010-03-11 2016-03-22 Abdominal treatment systems, delivery devices, and methods

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US31299010P 2010-03-11 2010-03-11
US61/312,990 2010-03-11
US13/043,987 2011-03-09
US13/043,987 US8469935B2 (en) 2010-03-11 2011-03-09 Abdominal treatment systems, delivery devices, and methods

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