WO2011069889A1 - Système de stockage, gestion et transport d'échantillons de laboratoire - Google Patents

Système de stockage, gestion et transport d'échantillons de laboratoire Download PDF

Info

Publication number
WO2011069889A1
WO2011069889A1 PCT/EP2010/068784 EP2010068784W WO2011069889A1 WO 2011069889 A1 WO2011069889 A1 WO 2011069889A1 EP 2010068784 W EP2010068784 W EP 2010068784W WO 2011069889 A1 WO2011069889 A1 WO 2011069889A1
Authority
WO
WIPO (PCT)
Prior art keywords
sample
magnetic
sample holder
recordings
sensors
Prior art date
Application number
PCT/EP2010/068784
Other languages
German (de)
English (en)
Inventor
André VON FRONREICH
Original Assignee
Glp Systems Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glp Systems Gmbh filed Critical Glp Systems Gmbh
Publication of WO2011069889A1 publication Critical patent/WO2011069889A1/fr

Links

Classifications

    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06Q—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES; SYSTEMS OR METHODS SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES, NOT OTHERWISE PROVIDED FOR
    • G06Q10/00—Administration; Management
    • G06Q10/08—Logistics, e.g. warehousing, loading or distribution; Inventory or stock management

Definitions

  • the invention relates to a system for the storage, management and transport of laboratory samples contained in sample vessels according to the preamble of patent claim 1.
  • An essential aspect of the overall management and treatment of individual laboratory samples is the unambiguous assignment of the samples throughout logistics, i. E. the clear assignment of specific measurement and analysis results to the samples as well as the targeted guidance of the samples along the logistic chain in the course of the laboratory analysis.
  • Samples are usually arranged in Probenhalter- or -trägem in which they remain during further processing and analysis, possibly also be implemented at other distribution points of a first
  • the sample containers are for the required traceability is typically provided with an identification, such as a barcode attached thereto.
  • an identification such as a barcode attached thereto.
  • these markings or identification codes are read out on the sample vessels for the tracking and continual identification of the samples on the sample holders, for example corresponding ones
  • the sample holder are provided with an individualized identification or coding in order to recognize these automatically readable and clearly assignable.
  • an individualized identification or coding in order to recognize these automatically readable and clearly assignable.
  • the system has the considerable advantage that a readout of an identifier on the sample holder can be made with much simpler equipment expense and also significantly more reliable. This is due to the fact that unlike the unpredictable arrangement of the sample vessel in the sample holder and thus the inaccurate alignment of the on the sample vessel
  • arranged identifier of the sample holder can be made so that the coding arranged thereon is mounted in a defined arrangement and position, which can always be read reliably in a correspondingly oriented reader.
  • the further aspect essential to the invention lies in the type of coding used here.
  • a magnetic coding is provided by in the sample holder in a given geometric arrangement (this can be
  • Magnetic recordings are formed. These magnetic recordings are in the simplest case holes or blind holes, can be inserted into the corresponding permanent magnet and set therein. These magnetic recordings are arranged in coordination with the permanent magnets used so that they leave a sufficient distance to the individual detection of a magnet within a magnetic recording or to detect the absence of such a magnet by the magnetic recording oppositely arranged sensors. In other words, the magnetic recordings should not be so close to each other that it is here too
  • Further components of the system are also in identification stations, for example in a transport system in an area in front of a switch, in front of an analysis apparatus, in one Distribution station for distributing arranged in a plurality of holding positions equipped sample holder sample vessels or the like., Arranged magnetic sensors. These are arranged in a pattern corresponding to the geometrical arrangement of the magnetic recordings in the sample holders and in such a way that they are in in the
  • Identification station located sample holders the coding area, in which the magnetic receptacles are formed in the respective sample holder, opposite and each of the magnetic sensors of a
  • the magnetic sensor If the magnetic sensor is polsensitive, it can detect whether a magnet in the magnetic receptacle with the north pole facing the sensor, with the south pole facing the sensor, or but no magnet available.
  • the magnetic sensor If the magnetic sensor is polsensitive, it can detect whether a magnet in the magnetic receptacle with the north pole facing the sensor, with the south pole facing the sensor, or but no magnet available.
  • Magnetic recordings are fitted with magnets, all in the same polar orientation, ie. with the south pole facing outwards, and magnetic sensors are used which only detect a magnetic field in this orientation, e.g. to respond to the south pole of a magnet with a signal. If, on the other hand, no magnets are present (or if the magnets with the north pole point outwards), the sensor will not output a signal or a "zero signal.” This results in a binary system in which each magnet recording contributes an information bit Magnetic recording results in the number of bits in the system
  • Magnetic recordings selected this results in 16 bits and thus 65,536 different coding options (starting from a total of empty magnetic recordings, without any placement to full placement with magnets).
  • the system has another advantage since magnetic field sensors are not only very reliable, but also work very fast, so that one
  • Trigger elements are provided to trigger the arrangement of magnetic sensors at the right time (i.e., the overlap with the magnetic receptacles) for detecting the respective magnets.
  • individualized coded sample carrier according to the invention is particularly well possible if the coding region is located on a
  • Holding positions can be used, it is advantageous if the geometric arrangement of the magnetic recordings is rotationally symmetrical about at least one angle of rotation.
  • Such a rotational symmetry (symmetry value 2) given by an angle of rotation permits overlapping of the magnetic recordings with the magnetic sensors aligned in accordance with the arrangement in two different ones
  • sample holders have higher symmetry (eg a rotational symmetry of 90 ° each, ie a symmetry with the valency 4), four different configurations of the magnetic recordings are connected to a single individualized sample holder, there is a further loss of a bit.
  • 16 magnetic recordings are then still 14 Bit for encryption available, with which 16.384 different sample carriers can be customized. If another bit is used here for internal purposes, 16 bits still hold 13 bits for the individualization of the sample holder, whereby still 8,192 different sample holders can still be identified individually.
  • Arrangement of the magnetic recordings results when this is formed like a matrix. In the case of 16 magnetic recordings per sample holder, this can be done, for example, in a column and line arrangement of magnetic recordings with four columns and four lines.
  • the magnetic sensors can be arranged with advantage in the identification station on a circuit board. This board also contributes
  • the controller is advantageously connected to a memory in which the data of the individualized sample holder are stored and linked in their current assembly with certain samples. This control can therefore detect the presence of a sample placed on a particular sample holder due to the reading out of the sample
  • Fig. 1 in a perspective view of a first sample holder of a system according to the invention for storage, management and the
  • Fig. 2 is a view of the sample holder of FIG. 1 obliquely from below to
  • FIG. 3 is a view obliquely from below of a second sample holder of the system according to the invention with the magnetic recordings;
  • Fig. 4 in a view obliquely from above a board with it in the
  • Fig. 1 is shown as part of a system according to the invention, a first sample holder 10 in a plan view obliquely from above.
  • Sample holder 10 has a plurality of upwardly projecting from a base plate 1 1 columns 12, which each form a holding place for a tubular sample vessel P between them four.
  • this sample holder 10 is known and conventional sample holder formed with a plurality of holding positions or places for sample systems. It serves to transport a plurality of samples in common, around these e.g.
  • These magnetic recordings 13 serve the individualized coding of the sample carrier 10.
  • permanent magnets are inserted into individual, in all or in none of the magnetic recordings and fixed there.
  • the permanent magnets are always with a like pole, in particular the south pole, the Side of the sample holder 10 facing.
  • Magnetic recordings with a magnet result in a total of 2 16 , so 65,536 individual ways to provide an arrangement of magnets here or just do not provide. This corresponds to a coding of 16 bits.
  • FIG. 3 an alternative sample holder 20 of a system according to the invention is shown.
  • the view of Fig. 3 is a three-dimensional view obliquely from below.
  • the sample holder 20 On its upper side, the sample holder 20 has a total of four support ribs 21, which form a receptacle for exactly one tube-shaped sample vessel P between them.
  • the sample holder with one of its base approximately square-shaped base 22 is provided on the underside in a similar manner as well as the sample holder 10 with magnetic receptacles 23, here also 16 in number.
  • These magnetic recordings 23 can also be equipped or released, as in the manner described above for coding the sample carrier 20 with permanent magnets that can be fixed there. Again, the assembly is to be seen so that the permanent magnets in the magnetic recording rest in the same polarity, pointing with the south pole out to the bottom of the base 22.
  • Another essential component of the system according to the invention is a board as shown in Fig. 4, on which correspond in one of the matrix-like arrangement of the magnetic recordings 13 and 23, respectively
  • Hall sensors 31 are supplied via on the circuit board 30 also provided, not shown here lines with electrical energy and are arranged on more on the board 30 lines for data or signal transmission
  • circuit board 30 and are the Hall sensors 31 with a not shown in detail
  • sample containing sample vessel P are read into the system. Furthermore, in an identification station in which the latter a circuit board 30 is arranged to detect the identification of the sample holder 10, 20 the sample holder 10, 20 is read out and assigned to the known sample. If the sample holder is one having a plurality of locations (sample holder 10), care must also be taken to ensure that the storage location or the holding position of the sample is also recorded and stored. In this way, the location of a particular sample is always assigned exactly to a sample holder 10,20 and possibly a parking position on the same.
  • the sample holder 10,20 can now be moved along a transport system, parked in distribution points, or logistically processed in any other way. Whenever a detection of the sample is important, a circuit board 30 is arranged in a corresponding identification station, which reads out the pattern of the loading of the magnetic recordings 13 or 23 with the Hall sensors 31 and thus the identification of the sample holder 10 or 20 recognizes. The control can now identify the latter via the stored sample assigned to this sample holder 10, 20 and decide on the further processing of this sample, set the course accordingly, set the analyzers and the like.
  • the sample holder 10 is provided with a rotational symmetry of valence 2, the sample holder 20 with a
  • Placement options of the magnetic recordings 23 are assigned, the possibility of individualization is reduced accordingly. But this also results in a higher degree of freedom in the operation of the
  • divalent symmetry may be via the reading of a corresponding Equipping the magnetic recording 23 at the same time information about its actual orientation are obtained, so that the pitches or holding positions of the individual sample containers P can still be tracked and detected according to the actual orientation of the sample holder 10.
  • the inventive system allows a fast, simple and robust identification and customization of the sample holder and thus with a corresponding assignment in a system detecting the currently held on the sample holders samples. This can also be done in motion, e.g. during the transport of a sample holder along a path, thus facilitating the largely automated operation of an analysis laboratory.

Landscapes

  • Business, Economics & Management (AREA)
  • Engineering & Computer Science (AREA)
  • Economics (AREA)
  • Quality & Reliability (AREA)
  • Entrepreneurship & Innovation (AREA)
  • Human Resources & Organizations (AREA)
  • Marketing (AREA)
  • Operations Research (AREA)
  • Development Economics (AREA)
  • Strategic Management (AREA)
  • Tourism & Hospitality (AREA)
  • Physics & Mathematics (AREA)
  • General Business, Economics & Management (AREA)
  • General Physics & Mathematics (AREA)
  • Theoretical Computer Science (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

L'invention concerne un système destiné au stockage, à la gestion et au transport d'échantillons de laboratoire contenus dans des éprouvettes (P) avec plusieurs supports d'échantillons transportables (10, 20) permettant de recevoir au moins une éprouvette (P) et avec au moins une station d'identification permettant d'identifier les supports d'échantillons (10, 20). La présente invention offre grâce à ce système une possibilité d'identifier de manière simple, fiable et ce sans perturber globalement les opérations dans le laboratoire d'analyse, des éprouvettes associées à un support d'échantillons. Pour cela, les supports d'échantillons (10, 20) présentent respectivement dans une zone de codage une pluralité de logements d'aimant (13, 23) qui peuvent être équipés individuellement d'aimants permanents dans un agencement géométrique identique pour tous les supports d'échantillons (10, 20) et qui sont équipés d'aimants permanents d'une manière différente pour chaque support d'échantillons (10, 20). De plus, la station d'identification contient des capteurs magnétiques (31) selon un agencement géométrique correspondant à l'agencement géométrique des logements d'aimant (13, 23) dans une zone de lecture qui, dans le cas du support d'échantillons (10, 20) se trouvant dans la station d'identification, est en regard de la zone de codage dudit support d'échantillons.
PCT/EP2010/068784 2009-12-07 2010-12-03 Système de stockage, gestion et transport d'échantillons de laboratoire WO2011069889A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP09178181A EP2339512A1 (fr) 2009-12-07 2009-12-07 Système pour le stockage, la gestion et le transport d'échantillons de laboratoire
EP09178181.5 2009-12-07

Publications (1)

Publication Number Publication Date
WO2011069889A1 true WO2011069889A1 (fr) 2011-06-16

Family

ID=41479638

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2010/068784 WO2011069889A1 (fr) 2009-12-07 2010-12-03 Système de stockage, gestion et transport d'échantillons de laboratoire

Country Status (2)

Country Link
EP (1) EP2339512A1 (fr)
WO (1) WO2011069889A1 (fr)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2565370A1 (fr) * 1984-06-01 1985-12-06 Rambaud Guy Dispositif de reception automatique de colis
US20030190057A1 (en) * 2001-08-02 2003-10-09 Toru Takehara Method and apparatus of automated optical container code recognition with positional identification for a transfer container crane
EP1699006A1 (fr) * 2005-03-04 2006-09-06 B & P Informatica S.r.l. Système pour surveiller la distribution des articles

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2565370A1 (fr) * 1984-06-01 1985-12-06 Rambaud Guy Dispositif de reception automatique de colis
US20030190057A1 (en) * 2001-08-02 2003-10-09 Toru Takehara Method and apparatus of automated optical container code recognition with positional identification for a transfer container crane
EP1699006A1 (fr) * 2005-03-04 2006-09-06 B & P Informatica S.r.l. Système pour surveiller la distribution des articles

Also Published As

Publication number Publication date
EP2339512A1 (fr) 2011-06-29

Similar Documents

Publication Publication Date Title
EP1733239B1 (fr) Dispositif et procede d'identification, de localisation et de poursuite d'objets situes sur des equipements de laboratoire
EP0738986B1 (fr) Analyseur avec lecteur de code à barres fixe
EP0738541B1 (fr) Support pour récipients
EP2030689B1 (fr) Supports de microplaquettes dotés d'aimants
DE102008050525A1 (de) Vorrichtung und Verfahren zur Kennzeichnung mindestens eines Objektträgers
DE102008050530A1 (de) Vorrichtung und Verfahren zur Aufbewahrung mindestens eines Objektträgers und mindestens einer Kassette
DE2758437A1 (de) Milchprobenflasche
WO2005107438A1 (fr) Systeme de prelevement automatique d'echantillons dans des vehicules de collecte du lait et des installations de traite
DE102007012524B4 (de) Behälterensemble sowie Verfahren zur Analyse von Substanzen
EP2371456B1 (fr) Cape de transport
EP2851684B1 (fr) Procédé et dispositif d'identification de fractions dans un collecteur de fraction d'un chromatographe en phase liquide
WO2011069889A1 (fr) Système de stockage, gestion et transport d'échantillons de laboratoire
EP4076264B1 (fr) Système de détection modulaire pour surveillance de circuit stérile et procédé de surveillance d'un circuit de matériau stérile
EP4334044A1 (fr) Installation de contrôle pour une pluralité d'objets à contrôler individualisables et unité de contrôle
EP2821773A1 (fr) Procédé et cartouche destinés à l'approvisionnement, le transport, la préparation et l'archivage d'échantillons thermo-analytiques
EP4146409A2 (fr) Installation de contrôle conçue pour une pluralité de corps distincts à contrôler
DE2118432B2 (de) Probenverteiler für die Untersuchung von Flüssigkeitsproben
DE102020115474A1 (de) Verfahren zur Überwachung eines Oberflächenbehandlungsprozesses und Anlage zur Oberflächenbehandlung eines Werkstücks
DE102006041695A1 (de) Anlage zur Durchführung von Blutanalysen
DE102012111369B3 (de) Verfahren zur Identifizierung und/oder Lokalisierung von in Behältern befindlichen Proben für eine automatische Probenzuführ- und/oder Probenabgabevorrichtung
AT399050B (de) Verfahren und vorrichtung zum identifizieren von aus zugelieferten flüssigkeitsmengen gezogenen und in probengefässe eingefüllten proben, insbesondere milchproben
DE3904258C2 (fr)
DE102021120340A1 (de) Smart Port - Multifunktionales Lese/Erkennungsgerät im Sterilgutkreislauf
EP3410340A1 (fr) Procédé d'alignement d'un film sur un code
DE102020134608A1 (de) Flüssigkeitsprobennahmevorrichtung

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 10785428

Country of ref document: EP

Kind code of ref document: A1

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 10785428

Country of ref document: EP

Kind code of ref document: A1