WO2011060484A1 - Procédé et dispositif pour un système de dosage de liquide - Google Patents

Procédé et dispositif pour un système de dosage de liquide Download PDF

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Publication number
WO2011060484A1
WO2011060484A1 PCT/AU2010/001526 AU2010001526W WO2011060484A1 WO 2011060484 A1 WO2011060484 A1 WO 2011060484A1 AU 2010001526 W AU2010001526 W AU 2010001526W WO 2011060484 A1 WO2011060484 A1 WO 2011060484A1
Authority
WO
WIPO (PCT)
Prior art keywords
liquid medicine
single dose
containers
array
medicine containers
Prior art date
Application number
PCT/AU2010/001526
Other languages
English (en)
Inventor
Chris Clarke
Original Assignee
Scatterbrain Pty Ltd Atf Scatterbrain Trust
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2009905665A external-priority patent/AU2009905665A0/en
Application filed by Scatterbrain Pty Ltd Atf Scatterbrain Trust filed Critical Scatterbrain Pty Ltd Atf Scatterbrain Trust
Priority to EP10830945A priority Critical patent/EP2501353A1/fr
Priority to CN2010800520025A priority patent/CN102639094A/zh
Priority to JP2012539144A priority patent/JP2013511298A/ja
Priority to CA2780967A priority patent/CA2780967A1/fr
Priority to US13/510,916 priority patent/US20120228317A1/en
Priority to AU2010321670A priority patent/AU2010321670A1/en
Publication of WO2011060484A1 publication Critical patent/WO2011060484A1/fr

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B3/00—Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, or jars
    • B65B3/003—Filling medical containers such as ampoules, vials, syringes or the like
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B43/00—Forming, feeding, opening or setting-up containers or receptacles in association with packaging
    • B65B43/42—Feeding or positioning bags, boxes, or cartons in the distended, opened, or set-up state; Feeding preformed rigid containers, e.g. tins, capsules, glass tubes, glasses, to the packaging position; Locating containers or receptacles at the filling position; Supporting containers or receptacles during the filling operation
    • B65B43/44—Feeding or positioning bags, boxes, or cartons in the distended, opened, or set-up state; Feeding preformed rigid containers, e.g. tins, capsules, glass tubes, glasses, to the packaging position; Locating containers or receptacles at the filling position; Supporting containers or receptacles during the filling operation from supply magazines
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B43/00—Forming, feeding, opening or setting-up containers or receptacles in association with packaging
    • B65B43/42—Feeding or positioning bags, boxes, or cartons in the distended, opened, or set-up state; Feeding preformed rigid containers, e.g. tins, capsules, glass tubes, glasses, to the packaging position; Locating containers or receptacles at the filling position; Supporting containers or receptacles during the filling operation
    • B65B43/54—Means for supporting containers or receptacles during the filling operation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B61/00—Auxiliary devices, not otherwise provided for, for operating on sheets, blanks, webs, binding material, containers or packages
    • B65B61/26—Auxiliary devices, not otherwise provided for, for operating on sheets, blanks, webs, binding material, containers or packages for marking or coding completed packages
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B7/00—Closing containers or receptacles after filling
    • B65B7/16—Closing semi-rigid or rigid containers or receptacles not deformed by, or not taking-up shape of, contents, e.g. boxes or cartons
    • B65B7/28—Closing semi-rigid or rigid containers or receptacles not deformed by, or not taking-up shape of, contents, e.g. boxes or cartons by applying separate preformed closures, e.g. lids, covers
    • B65B7/2842—Securing closures on containers
    • B65B7/2871—Securing closures on containers by gluing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D1/00—Containers having bodies formed in one piece, e.g. by casting metallic material, by moulding plastics, by blowing vitreous material, by throwing ceramic material, by moulding pulped fibrous material, by deep-drawing operations performed on sheet material
    • B65D1/22—Boxes or like containers with side walls of substantial depth for enclosing contents
    • B65D1/26—Thin-walled containers, e.g. formed by deep-drawing operations
    • B65D1/30—Groups of containers joined together end-to-end or side-by-side
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D77/00—Packages formed by enclosing articles or materials in preformed containers, e.g. boxes, cartons, sacks or bags
    • B65D77/04—Articles or materials enclosed in two or more containers disposed one within another
    • B65D77/0446—Articles or materials enclosed in two or more containers disposed one within another the inner and outer containers being rigid or semi-rigid and the outer container being of polygonal cross-section not formed by folding or erecting one or more blanks
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D77/00—Packages formed by enclosing articles or materials in preformed containers, e.g. boxes, cartons, sacks or bags
    • B65D77/10—Container closures formed after filling
    • B65D77/20—Container closures formed after filling by applying separate lids or covers, i.e. flexible membrane or foil-like covers
    • B65D77/2024—Container closures formed after filling by applying separate lids or covers, i.e. flexible membrane or foil-like covers the cover being welded or adhered to the container
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B2210/00—Specific aspects of the packaging machine
    • B65B2210/06—Sterilising or cleaning machinery or conduits
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D2203/00—Decoration means, markings, information elements, contents indicators
    • B65D2203/10—Transponders
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D2577/00—Packages formed by enclosing articles or materials in preformed containers, e.g. boxes, cartons, sacks, bags
    • B65D2577/04—Articles or materials enclosed in two or more containers disposed one within another
    • B65D2577/041—Details of two or more containers disposed one within another
    • B65D2577/042—Comprising several inner containers
    • B65D2577/043—Comprising several inner containers arranged side by side

Definitions

  • the present invention generally relates to a liquid dosing system for the delivery of pharmaceutical liquid into dosage containers. Discussion of the Background Art
  • liquid medicine is initially packaged in bulk storage containers for shipment to pharmacies or health care settings, individual dosing of the liquid medicine is often carried out in health care settings by qualified staff members.
  • a bulk storage container such as a bottle
  • the staff member has to open the bottle and measure the dose to be administered into a calibrated cup.
  • the packaging of liquid medicine into single dosage units requires a great deal of accuracy and a high level of sterility.
  • Such dosing liquids is a time-intensive and tedious task requiring multiple steps and a great deal of diligence on the part of the staff member charged with the task.
  • Some existing automated packaging devices provide means for single unit dosage packaging in the form of a dispenser for dispensing liquid medicine into individual unit dosage containers.
  • Such packaging devices use various individual steps to fill the individual unit dosage containers, such as mini cups; then seal the individual containers one by one; and then print information on the seal of each individual container.
  • These packaging devices are inefficient as they require manual user input at almost every stage of the packaging process.
  • the degree of sterility is lessened with each requirement for human interaction.
  • packaging devices which produce single unit dosage cups present problems for storage and transport of the final products.
  • the present invention reduces or ameliorates one or all of the above problems of conventional manual and automated packaging methods.
  • a liquid dosing system delivers liquid medicine from a bulk supply into single dosage liquid medicine containers.
  • the liquid dosing system comprises one or more dispensing points for filling single dosage liquid medicine containers of an array of single dosage liquid medicine containers with liquid medicine from the bulk supply; a platform for supporting the array of single dosage liquid medicine containers; and a control device for controlling the relative position of the dispensing point and the platform.
  • the single dosage liquid medicine containers of an array can be removably joined to each other via frangible tabs, such that a detached single dosage container is absent of residual sharp edges.
  • the containers are preferably sealed and may be provided with a removable tamper proof closure.
  • the containers may be labelled with printed information relating the liquid medicine contained therein.
  • Embodiments of the present invention include a liquid medicine delivery system comprising a racking or storage device for racking or storing the array of single dosage liquid medicine containers. Printed information remains to be visible even when the array of single dosage liquid medicine containers is placed in the racking or storage device.
  • inventions further include a user input device for controlling the delivery of the liquid medicine.
  • FIG. 1 provides an illustration of a liquid dosing system according to two embodiments of the invention
  • FIG. 2A provides an illustration of an uncovered array of single dosage liquid medicine containers according to one embodiment of the invention
  • FIG. 2B provides an illustration of a covered array of single dosage liquid medicine containers according to the invention corresponding to Fig. 2A;
  • FIG. 2C provides an illustration of a covered single dosage liquid medicine container according to the embodiment of the invention corresponding to Figs. 2A and 2B;
  • FIG. 2D provides an illustration of a single dosage liquid medicine container with a partially peeled off cover according to the embodiment of the invention corresponding to Figs. 2A to 2C;
  • FIG. 2E provides an illustration of an open single dosage liquid medicine container according to the embodiment of the invention corresponding to Figs. 2A to 2D;
  • FIG.3A provides an illustration of an uncovered array of single dosage liquid medicine containers according to one embodiment of the invention.
  • FIG. 3B provides an illustration of a covered array of single dosage liquid medicine containers according to the invention corresponding to Fig. 3A
  • FIG. 3C provides an illustration of a covered single dosage liquid medicine container according to the embodiment of the invention corresponding to Figs. 3A and 3B
  • FIG. 3D provides an illustration of a single dosage liquid medicine container with a partially peeled off cover according to the embodiment of the invention corresponding to Figs. 3A to 3C;
  • FIG. 3E provides an illustration of an open single dosage liquid medicine container according to the embodiment of the invention corresponding to Figs. 3A to 3D;
  • FIG.4A provides an illustration of an uncovered array of single dosage liquid medicine containers according to one embodiment of the invention.
  • FIG. 4B provides an illustration of an open single dosage liquid medicine container according to the embodiment of the invention corresponding to Fig. 4A;
  • FIG. 5A provides an illustration of an empty liquid medicine dosage container storage tray according to one embodiment of the invention.
  • FIG. 5B provides an illustration of a racked liquid medicine dosage container storage tray according to one embodiment of the invention.
  • FIG. 6 provides an illustration of a dispensing hopper according to the invention corresponding to Fig. 1 ;
  • FIG. 7A provides an illustration of a plurality of bulk liquid medicine storage containers in a rotary support according to the invention corresponding to Fig 1 ;
  • FIG. 7B provides an illustration of a plurality of bulk liquid medicine storage containers in an in-line support according to the invention corresponding to Fig 1. DESCRIPTION OF EMBODIMENTS OF THE INVENTION
  • a system 100 for delivering liquid medicine 102 from a bulk supply 104 into an array 106 of single dosage liquid medicine containers there is provided a system 100 for delivering liquid medicine 102 from a bulk supply 104 into an array 106 of single dosage liquid medicine containers.
  • the bulk supply 104 is shown to be in the form of one or more bulk storage containers. However, in an alternative embodiment, the bulk supply 104 can be in the form of a pipe or a hose supplying liquid medication from a remote location.
  • the first exemplary embodiment shows a moveable support 220 for holding a number of bulk storage containers 104 and moving a selected container into a desired position.
  • the moveable support 220 is in the form of a linear support mechanism, which, for example, can work on the basis of a conveyor system.
  • the second exemplary embodiment also shows a movable support 320 for holding a number of bulk storage containers 104 and moving a selected container into a desired position.
  • the moveable support 320 is in the form of a rotary support, such as a carousel or a cassette, for example.
  • Each array 106 of single dosage liquid medicine containers may be an integral one or two-dimensional array. According to these exemplary embodiments of the present invention, each array 106 of single dosage liquid medicine containers is supported by platform 108. Platform 108 is moveable over platform support 122 such that the position of platform 108 can be controlled relative to the position of dispensing point 110. In an alternative embodiment, dispensing point 110 is moveable such that its position is controlled relative to platform 108. In yet another alternative embodiment, the position of both platform 108 and dispensing point 110 is controlled relative to one another. Dispensing point 110 fills each array 106 of single dosage liquid medicine containers with liquid medicine 102 from bulk storage supply 104. Each array 106 of single dosage liquid medicine containers is configured to be stacked inside dispensing hopper 120. At the beginning of the filling, sealing and labelling process, dispensing hopper 120 dispenses one array 106 of single dosage liquid medicine containers onto carrier platform 108 for movement towards dispensing point 1 10.
  • dispensing point 1 10 may be configured as a single nozzle adapted to discharge liquid medicine 102.
  • dispensing point 1 10 may be configured as an array of nozzles adapted to discharge the liquid medicine at a plurality of points.
  • the array of nozzles may be configured as a one or two-dimensional array.
  • the system may be configured to select from the plurality of dispensing points or use more than one dispensing point at the same time to fill an array of single dosage liquid containers with liquid medicine from a selected bulk storage supply.
  • Such a dispensing system could include control over which of the plurality of dispensing points are used for different sized arrays of single dosage liquid medicine containers. For example, an array of 5 x 3 single dosage liquid medicine containers could be filled by activating 3 dispensing points or 5 dispensing points depending on its orientation.
  • system 00 is provided with peristaltic pump 424 for supplying liquid medicine 102 to dispensing point 1 10.
  • FIG. 1 Also shown in Fig. 1 , is an alternative embodiment where system 100 is provided with pinch tube valve 524 for supplying liquid medicine 102 to dispensing point 110.
  • the system 100 of the present invention includes a sealing component 112 for sealing an array 106 of single dosage liquid medicine containers and a printing or labelling component 114 for labelling the array 106 of single dosage liquid medicine containers with printed information relating to the liquid medicine contained therein.
  • the information printed on the array 106 of removably joined single dosage liquid medicine containers may contain details relating to: content, dose volume, dose information, patient name, patient address, doctor, batch and expiry information, colour code, and/or identification code.
  • labelling component 1 14 may be an RFID writer.
  • labelling component 114 is configured to write data to an RFID tag either embedded or attached to each array 106 of single dosage liquid medicine containers. Akin to the printed information, the written data may contain details relating to: content, dose volume, dose information, patient name, patient address, doctor, batch and expiry information, colour code, and/or identification code.
  • user input device 1 16 is used to control the delivery of liquid medicine into the array 106 of single dosage containers.
  • the user input device 1 16 can be adapted to utilise input from external sources.
  • the user input device 1 16 is shown to be in the form of a computer.
  • the user input device 116 can be used to control: the position of dispensing point 110 or plurality of dispensing points; the activation of a selection of dispensing points in the case of a plurality of dispensing points;
  • the labelling component 1 14 or • any other part of the process involved in dispensing liquid medicine 102 from a bulk supply 104 into an array 06 of single dosage containers.
  • User input device 1 16 not only controls all stages of system 100, but also provides feedback to the user on the status of system 100 during operation.
  • barcode reader 124 is used to scan bulk storage containers 104 to ensure that the correct drug (liquid medicine) and strength is being used. Scanning of bulk storage containers 104 can also be used to provide the user input device with batch and expiry data.
  • barcode reader 124 is used to scan the original container to ensure that the correct drug (liquid medicine) and strength is being used. Once the drug is verified, the user may key in batch and expiry data into user input device 16.
  • System 100 illustrated in these embodiments of the present invention also includes optical or digital reader 1 18 for checking the final product prior to dispatch or storage.
  • Optical or digital reader 1 18 can be configured to check the printed information or the data on the RFID tag on each array 106 of single dosage liquid medicine containers and verify the accuracy and completeness of the filling, printing and sealing process.
  • FIG. 2A an integral array of single dosage medicine containers 200 is shown in a planar formation.
  • the array of single dosage containers 200 is shown to comprise of fifteen removably joined single dosage medicine containers, whereby the array of single dosage containers comprises a matrix of five single dosage medicine containers 202 in a first dimension and three single dosage medicine containers 204 in a second dimension.
  • the array of single dosage containers 200 comprises frame 206 which borders each of the single dosage containers 205.
  • the array of single dosage containers 200 further comprises frangible bridging portions 208 removably joining each single dosage container 205 to frame 206.
  • the array of single dosage containers 200 also comprises tab portion 210 displaying information 212.
  • information 212 is shown as printed information.
  • information 212 may in be in the form of an RFID tag, or in the form of both printed information and RFID tag.
  • the RFID tag can be either embedded or attached to either tab portion 210 of the array 200; or cover 214 of the array 200.
  • the array of single dosage containers 200 has an outer frame bordering the outer circumference of the array.
  • Frangible bridging portions 208 allow for any of the single dosage containers 205 to be removed, one at a time, from the array of single dosage containers 200 regardless of its position relative to other single dosage containers.
  • the array of single dosage containers 200 is configured such that removal of a single dosage container 205 leaves frangible bridging portion 208 attached to frame 206. As will be described with reference to Figs. 2C to 2E, this provides a discrete single dosage container 205 that is free of residual edges.
  • Fig. 2B there is shown an array of single dosage medicine containers 200 wherein the containers are covered. Covers 214 are applied to the array of single dosage medicine containers 200 to provide a completely tamper proof enclosure to.
  • each single dosage liquid medicine container 205 allowing the array of single dosage liquid medicine containers 200 to be stored or transported in any position and also allowing the user to carry each discrete container 205 in any position.
  • information 212 and 216 is shown to be printed on both the tab portion 210 of the array of containers 200 and other surfaces of the covers 214 on each container 205.
  • information 212 and .216 may alternatively be in the form of an RFID tag, or in the form of both printed information and an RFID tag.
  • the RFID tag can be either embedded within tab portion 210 and/or covers 214 or affixed on top of tab portion 210 and/or covers 214.
  • the covers 214 are applied to the array 200 of single dosage medicine containers by adhesive sealing methods.
  • Figs. 2C to 2E illustrate a discrete single dosage liquid medicine container 205 having been removed from an array of single dosage containers 200 as shown in Figs. 2A and 2B.
  • the discrete container 205 includes a receptacle 218 formed of a base 220 and a conical wall 222.
  • the top of the discrete container 205 includes a flange 224.
  • An upper surface of the flange 224 receives a cover 214 for securing the contents of the discrete container 205.
  • Outer margin 226 of cover 214 is designed to adhesively seal onto flange 224 of the discrete container 205.
  • each discrete single dosage liquid medicine container 205 is broken away from a frangible bridging portion 208 such that the frangible bridging portion 208 remains attached to the frame 206 rather than the discrete container 205. This is especially advantageous when used by elderly patients with fragile skin.
  • the cover 214 acts to maintain the integrity of the liquid medication by preventing interaction with potential degradants, such as moisture, oxygen or dust.
  • each discrete container 205 relates to the liquid medicine contained within each discrete container 205, such as content, dose volume, dose information, patient name, patient address, doctor, batch and expiry information, colour code, and/or identification code.
  • Fig. 3A illustrates an alternative embodiment of the present invention whereby the plurality of single dosage medicine containers are removably joined to each other in the form of bridging portions 304 provided on flange 318 rather than perforations 206 as shown in Fig. 2A.
  • Fig. 3A also illustrates the display of information 306 relating to the liquid medication in each of the single dosage containers printed on the tab portion 302 of the array 300 of single dosage containers.
  • the discrete single dosage liquid medicine container 310 is shown to have been removed from an array 300 corresponding to the embodiment described with reference to Fig. 3A.
  • the discrete container 310 includes a receptacle 312 formed of a base 314 and a continuous conical wall 316.
  • the top of the discrete container 310 includes a flange 318.
  • the top surface of the flange 318 receives a cover (not shown) for securing the contents of the discrete container 310.
  • an outer margin of the cover is designed to adhesively seal onto the flange 318 of the discrete container 310.
  • the flange 318 of the discrete container 310 includes bridging portions 304 which were removably joined to bridging portions of at least two neighbouring single dosage liquid medicine containers in the array 300 as shown in Fig. 3A. Bridging portions 304 of the discrete container 310 shown here in Fig. 3A together with bridging portions of at least two neighbouring containers (not shown in this Figure) are removably joined to each other, via a weakened or frangible joint as described with reference to Fig. 3A.
  • Figs. 3C to 3E illustrate a discrete single dosage liquid medicine container 310 having been removed from an array of single dosage containers 300 as shown in Figs. 3A and 3B.
  • the discrete container 310 includes a receptacle 312 formed of a base 314 and a conical wall 316.
  • the top of the discrete container 310 includes a flange 318.
  • An upper surface of the flange 318 receives a cover 322 for securing the contents of the discrete container 310.
  • Outer margin 324 of cover 322 is designed to adhesively seal onto flange 318 of the discrete container 310.
  • Fig. 3D shows a discrete single dosage liquid medicine container 310 with a partially peeled-off cover 322.
  • Cover 322 is adhesively sealed to. flange 318 of the discrete container 310.
  • a user can easily remove the cover 322 and consume the contents residing in the receptacle 312 of the discrete container 310.
  • a user can consume the contents with cover 322 only partially peeled-off flange 318 or with cover 322 completely removed from flange 318 as shown in Figs. 3C.
  • Such discrete dosage containers 310 may typically range in size from 5ml_ to 50mL.
  • cover 322 acts to maintain the integrity of the liquid medication by preventing interaction with potential degradants, such as moisture, oxygen or dust.
  • Printed information 306 on the cover 322 of each discrete container 310 relates to the liquid medicine contained within each discrete container 310, such as content, dose volume, dose information, patient name, patient address, doctor, batch and expiry information, colour code, and/or identification code.
  • an alternative embodiment of an integral array 400 of single dosage medicine containers is shown in a planar formation.
  • the array 400 of single dosage containers is shown to comprise of fifteen removably joined single dosage medicine containers, whereby the array 400 comprises a matrix of five single dosage medicine containers 402 in a first dimension and three single dosage medicine containers 404 in a second dimension.
  • Also shown in Fig. 4A are frangible portions in the form of perforations 406 between each single dosage medicine container and another.
  • the perforations 406 allow for each single dosage medicine container to be removed, one at a time, from the array 400.
  • the perforations 406 allow for a selected number of single dosage medicine containers to be removed from the array 400.
  • a patient prescribed with three doses of medication per day may choose to remove three single dosage medicine containers from the array 400 leaving the three removed single dosage medicine containers attached to each other.
  • a tab portion 408 of the array 400 of single dosage containers is used for the display of information relating to the liquid medicine contained within the containers. Such information includes, but is not limited to, content, dose volume, dose information, patient name, patient address, doctor, batch and expiry information, colour code, and/or identification code, suitable for scanning.
  • Fig. 4B illustrates a discrete single dosage liquid medicine container 410 having been removed from an array 400 of single dosage containers as shown in Fig. 4A.
  • the discrete container 410 includes a receptacle 412 formed of a base 414 and a continuous conical wall 416.
  • the top of the discrete container 410 includes a flange 418.
  • An upper surface of the flange 418 receives a cover (not shown) for securing the contents of the discrete container 410.
  • An outer margin of the cover is designed to adhesively seal onto the flange 418 of the discrete container 410.
  • the flange 418 of the discrete container 410 includes flat edge portions 420 which were removably joined to the edges of at least two neighbouring single dosage liquid medicine containers in the an array 400 as shown in Fig. 4A.
  • the flat edge portions 420 of the discrete container 410 shown here in Fig. 4B together with flat edge portions of at least two neighbouring containers (not shown in this Figure) are removable joined to each other via perforations 406 in the joints as shown in Fig. 4A.
  • Fig. 5A shows a storage tray 500 according to one embodiment of the present invention.
  • the storage tray 500 is shown to comprise of a plurality of slots 502 with each slot 502 configured to receive an array of single dosage containers (not shown in this Figure).
  • the storage tray 500 is designed to be placed in a transport mechanism such as a trolley or conveyer belt.
  • the storage tray 500 is designed in the form of a rectangular box.
  • the storage tray may be designed in any other form depending on its application.
  • Fig. 5B shows the storage tray 500 racked with a plurality of arrays 300 of single dosage containers. Each array 300 slides into a slot 502 of the storage tray 500.
  • the storage tray 500 is designed such that information 324 and 306 printed on each of the single dosage containers and on the tab portion 302 of the array 300 remains visible after placement of the arrays 300 into the storage tray 500 suitably by a transport mechanism associated with support 122 (see Figure 1). This provides a user with the capabilities of identifying an array 300 of single dosage containers and its contents without removal of the array 300 from the storage tray 500.
  • information 324 and 306 is shown in the form of printed text.
  • information 324 and 306 may be in the form of an RFID tag, or in the form of both printed information and RFID tag.
  • Fig. 6 illustrates a dispensing hopper 600 according to one embodiment of the invention.
  • Dispensing hopper 600 is designed to carry a plurality of arrays 602 of single dosage containers as described with reference to other figures and is configured to carry arrays of different sizes. Operation of dispensing hopper 600 is controlled by user input device 1 16.
  • dispensing hopper 600 dispenses one or more arrays 602 of single dose containers onto movable carrier platform 108 as described with reference to Fig. 1.
  • Carrier platform 108 then controls placement of each array of single dose containers and their passage through the filling, sealing, labelling, and checking process.
  • Fig. 7A provides a more detailed illustration of the moveable support 220 shown briefly in Fig. 1. In this exemplary embodiment, moveable support 220 is shown in the form of a linear support holding four bulk storage containers 221.
  • FIG. 7B provides a more detailed illustration of the moveable support 320 shown briefly in Fig. 1.
  • moveable support 320 is shown in the form of a rotary carousel or cassette holding three bulk storage containers 321.
  • the user input device 1 16 described with reference to Fig. 1 controls either moveable support 220 or 320 to move a selected bulk storage container into a position for dispensing liquid medication.
  • the user input device 116 controls the moveable support 220 or 320 to shift in linear fashion or rotate respectively thus moving an alternative bulk storage container into a dispensing position.

Landscapes

  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Ceramic Engineering (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

Système et procédé pour délivrer un médicament liquide à partir d'une alimentation de stockage en vrac dans un réseau intégré de récipients de médicament liquide à dose unique avec une commande de la position relative d'un point de distribution et d'une plate-forme qui supporte le réseau de récipients à dose unique, et pour installer en rayon le réseau de récipients dans un dispositif de stockage.
PCT/AU2010/001526 2009-11-19 2010-11-16 Procédé et dispositif pour un système de dosage de liquide WO2011060484A1 (fr)

Priority Applications (6)

Application Number Priority Date Filing Date Title
EP10830945A EP2501353A1 (fr) 2009-11-19 2010-11-16 Procédé et dispositif pour un système de dosage de liquide
CN2010800520025A CN102639094A (zh) 2009-11-19 2010-11-16 用于液体剂量系统的方法和设备
JP2012539144A JP2013511298A (ja) 2009-11-19 2010-11-16 液体ドージングシステムの方法および装置
CA2780967A CA2780967A1 (fr) 2009-11-19 2010-11-16 Procede et dispositif pour un systeme de dosage de liquide
US13/510,916 US20120228317A1 (en) 2009-11-19 2010-11-16 Method and apparatus for liquid dosing system
AU2010321670A AU2010321670A1 (en) 2009-11-19 2010-11-16 Method and apparatus for liquid dosing system

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AU2009905665 2009-11-19
AU2009905665A AU2009905665A0 (en) 2009-11-19 Method and apparatus for liquid dosing system

Publications (1)

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WO2011060484A1 true WO2011060484A1 (fr) 2011-05-26

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PCT/AU2010/001526 WO2011060484A1 (fr) 2009-11-19 2010-11-16 Procédé et dispositif pour un système de dosage de liquide

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US (1) US20120228317A1 (fr)
EP (1) EP2501353A1 (fr)
JP (1) JP2013511298A (fr)
CN (1) CN102639094A (fr)
AU (1) AU2010321670A1 (fr)
CA (1) CA2780967A1 (fr)
WO (1) WO2011060484A1 (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104045036A (zh) * 2013-01-31 2014-09-17 蒋其伟 中药复方制剂的灌装机
WO2018019950A1 (fr) * 2016-07-27 2018-02-01 Philip Morris Products S.A. Récipient à élément radiofréquence
WO2018019868A1 (fr) * 2016-07-27 2018-02-01 Jt International S.A. Procédé et appareil de fabrication d'une capsule remplie de liquide

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20150374585A1 (en) * 2014-06-30 2015-12-31 Carefusion 303, Inc. System and method for compounding medication
CN109254132B (zh) * 2018-10-12 2023-11-21 中国环境科学研究院 一种模拟池塘生态系统的微宇宙实验装置
CN112817037A (zh) * 2020-12-28 2021-05-18 江苏万略医药科技有限公司 一种放射性药物活度快速测算装置及方法

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3503493A (en) * 1968-01-08 1970-03-31 Hoffmann La Roche Medicament packaging device
US3876268A (en) * 1973-11-09 1975-04-08 Robert W Colver Medicine dosage system
US4019793A (en) * 1975-03-14 1977-04-26 Gerding Paul W Pharmaceutical dosage distribution apparatus
US6189292B1 (en) * 1998-03-13 2001-02-20 Becton Dickinson And Company Method and apparatus for manufacturing, filling and packaging medical devices and medical containers
WO2003084653A1 (fr) * 2002-04-03 2003-10-16 E.I. Du Pont De Nemours And Company Appareil de distribution
US20050178092A1 (en) * 2004-02-13 2005-08-18 Pearson Walter G. Packaging system and related method
WO2005109948A2 (fr) * 2004-04-24 2005-11-17 Inrange Systems, Inc. Support universel a medicaments
WO2008026020A1 (fr) * 2006-09-01 2008-03-06 Fellgate Limited Plaquette blister
WO2010022345A2 (fr) * 2008-08-22 2010-02-25 Robert Terzini Système de dispersion et de remplissage de contenant
WO2010033262A1 (fr) * 2008-09-19 2010-03-25 Walgreen Co. Procédé et système de détermination d'un ordre de chargement pour une pluralité de pilules dans une boîte de médicaments à doses multiples

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6302299B1 (en) * 1999-04-16 2001-10-16 The Coca-Cola Company Bulk fountain syrup delivery and storage system
JP4210530B2 (ja) * 2003-03-04 2009-01-21 ニプロ株式会社 液体収容部連結体およびその液体収容部連結体の製作方法
WO2005073124A2 (fr) * 2004-01-20 2005-08-11 3M Innovative Properties Company Ensemble distributeur de liquide a utiliser avec un appareil
ITBO20060128A1 (it) * 2006-02-21 2007-08-22 Tema Sinergie S R L Macchina dosatrice di liquido radioattivo.

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3503493A (en) * 1968-01-08 1970-03-31 Hoffmann La Roche Medicament packaging device
US3876268A (en) * 1973-11-09 1975-04-08 Robert W Colver Medicine dosage system
US4019793A (en) * 1975-03-14 1977-04-26 Gerding Paul W Pharmaceutical dosage distribution apparatus
US6189292B1 (en) * 1998-03-13 2001-02-20 Becton Dickinson And Company Method and apparatus for manufacturing, filling and packaging medical devices and medical containers
WO2003084653A1 (fr) * 2002-04-03 2003-10-16 E.I. Du Pont De Nemours And Company Appareil de distribution
US20050178092A1 (en) * 2004-02-13 2005-08-18 Pearson Walter G. Packaging system and related method
WO2005109948A2 (fr) * 2004-04-24 2005-11-17 Inrange Systems, Inc. Support universel a medicaments
WO2008026020A1 (fr) * 2006-09-01 2008-03-06 Fellgate Limited Plaquette blister
WO2010022345A2 (fr) * 2008-08-22 2010-02-25 Robert Terzini Système de dispersion et de remplissage de contenant
WO2010033262A1 (fr) * 2008-09-19 2010-03-25 Walgreen Co. Procédé et système de détermination d'un ordre de chargement pour une pluralité de pilules dans une boîte de médicaments à doses multiples

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104045036A (zh) * 2013-01-31 2014-09-17 蒋其伟 中药复方制剂的灌装机
WO2018019950A1 (fr) * 2016-07-27 2018-02-01 Philip Morris Products S.A. Récipient à élément radiofréquence
WO2018019868A1 (fr) * 2016-07-27 2018-02-01 Jt International S.A. Procédé et appareil de fabrication d'une capsule remplie de liquide

Also Published As

Publication number Publication date
CA2780967A1 (fr) 2011-05-26
CN102639094A (zh) 2012-08-15
AU2010321670A1 (en) 2012-05-17
JP2013511298A (ja) 2013-04-04
US20120228317A1 (en) 2012-09-13
EP2501353A1 (fr) 2012-09-26

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