WO2011058336A3 - Tablet comprising gum arabic - Google Patents

Tablet comprising gum arabic Download PDF

Info

Publication number
WO2011058336A3
WO2011058336A3 PCT/GB2010/002109 GB2010002109W WO2011058336A3 WO 2011058336 A3 WO2011058336 A3 WO 2011058336A3 GB 2010002109 W GB2010002109 W GB 2010002109W WO 2011058336 A3 WO2011058336 A3 WO 2011058336A3
Authority
WO
WIPO (PCT)
Prior art keywords
tablet
gum arabic
weight
saccharide
polyol
Prior art date
Application number
PCT/GB2010/002109
Other languages
French (fr)
Other versions
WO2011058336A2 (en
Inventor
Afzal Rahman Mohammed
Farhan Alhusban
Yvonne Perrie
Original Assignee
Aston University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aston University filed Critical Aston University
Publication of WO2011058336A2 publication Critical patent/WO2011058336A2/en
Publication of WO2011058336A3 publication Critical patent/WO2011058336A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4166—1,3-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2063—Proteins, e.g. gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

A tablet comprising: a pharmaceutically active agent; Gum Arabic; an agent selected from a saccharide, a polyol, an amino acid and mixtures of two or more thereof; and wherein the tablet comprises at least 30% by weight of Gum Arabic based on the total weight of the tablet.
PCT/GB2010/002109 2009-11-16 2010-11-16 Tablet WO2011058336A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0920041.1A GB0920041D0 (en) 2009-11-16 2009-11-16 Tablet
GB0920041.1 2009-11-16

Publications (2)

Publication Number Publication Date
WO2011058336A2 WO2011058336A2 (en) 2011-05-19
WO2011058336A3 true WO2011058336A3 (en) 2012-01-12

Family

ID=41509450

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2010/002109 WO2011058336A2 (en) 2009-11-16 2010-11-16 Tablet

Country Status (2)

Country Link
GB (1) GB0920041D0 (en)
WO (1) WO2011058336A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI3576795T1 (en) * 2017-02-03 2021-07-30 Berlin-Chemie Ag Oral thyroid therapeutic agent
WO2020112158A1 (en) * 2018-11-30 2020-06-04 Amerilab Technologies, Inc. Effervescent tablets that include crystalline sugar binder and methods of making the same
CN111529545B (en) * 2020-05-07 2022-06-07 四川农业大学 Composition for relieving degenerative neuropathy and application
CN113069425B (en) * 2021-04-06 2022-04-15 北京菲瑞阳林医药技术研发有限公司 N-acetylneuraminic acid sugar-containing freeze-dried flash-release tablet and preparation method thereof

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5516530A (en) * 1991-12-20 1996-05-14 Pfizer Inc. Porous shaped delivery devices and method of producing thereof
DE20102817U1 (en) * 2000-02-23 2001-06-07 Bolder Arzneimittel Gmbh Lozenges and chewing pills with cyclodextrin
US20030206948A1 (en) * 1997-07-10 2003-11-06 Gerhard Gergely Soluble, gum-containing, coated chewable tablet
WO2004041153A2 (en) * 2002-05-07 2004-05-21 Fein Seymour H Pharmaceutical composition including low dosages of desmopressin
WO2005023226A1 (en) * 2003-09-05 2005-03-17 Arrow No. 7 Limited Buccal drug delivery
US20090117172A1 (en) * 2005-03-28 2009-05-07 Ed Rogers Oral delivery vehicle and material

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100366294C (en) 2004-04-30 2008-02-06 量子高科（北京）研究院有限公司 Oral cavity quick dissolving preparation and production method thereof

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5516530A (en) * 1991-12-20 1996-05-14 Pfizer Inc. Porous shaped delivery devices and method of producing thereof
US20030206948A1 (en) * 1997-07-10 2003-11-06 Gerhard Gergely Soluble, gum-containing, coated chewable tablet
DE20102817U1 (en) * 2000-02-23 2001-06-07 Bolder Arzneimittel Gmbh Lozenges and chewing pills with cyclodextrin
WO2004041153A2 (en) * 2002-05-07 2004-05-21 Fein Seymour H Pharmaceutical composition including low dosages of desmopressin
WO2005023226A1 (en) * 2003-09-05 2005-03-17 Arrow No. 7 Limited Buccal drug delivery
US20090117172A1 (en) * 2005-03-28 2009-05-07 Ed Rogers Oral delivery vehicle and material

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CHANDRASEKHAR R ET AL: "The role of formulation excipients in the development of lyophilised fast-disintegrating tablets", EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, ELSEVIER SCIENCE PUBLISHERS B.V., AMSTERDAM, NL, vol. 72, no. 1, 1 May 2009 (2009-05-01), pages 119 - 129, XP026076613, ISSN: 0939-6411, [retrieved on 20081203], DOI: 10.1016/J.EJPB.2008.11.011 *

Also Published As

Publication number Publication date
GB0920041D0 (en) 2009-12-30
WO2011058336A2 (en) 2011-05-19

Similar Documents

Publication Publication Date Title
WO2009062746A3 (en) Topical drugs for use in antifungal therapy
WO2006084164A8 (en) Gastric retention and controlled release delivery system
WO2007135193A3 (en) Sustained-release alcohol-resistant multimicroparticulate oral pharmaceutical form comprising anti-misuse means
EP1730163A4 (en) Pharmaceuticals salts of 3-o-(3,3-dimethylsuccinyl) betulinic acid
WO2011049706A8 (en) Orally transformable tablets
WO2008128775A3 (en) Stabilised pharmaceutical composition containing pregabaline
WO2007086001A3 (en) Novel pyridine derivatives
WO2006127941A3 (en) Amorphous cinacalcet hydrochloride and preparation thereof
WO2010066749A3 (en) Ulipristal acetate tablets
WO2006118884A3 (en) Drug delivery devices and related components, systems and methods
WO2007144169A3 (en) Entacapone-derivatives
HUP0501139A2 (en) An optically active carbamic acid derivative, method for producing the same and use as a pharmaceutical intermediate
WO2006008173A3 (en) Pharmaceutical formulations for inhalation
WO2010052466A3 (en) Pharmaceutical aerosol composition
WO2008003050A3 (en) Gallium nitrate formulations
WO2011058336A3 (en) Tablet comprising gum arabic
WO2006128847A3 (en) Medicament containing a betamimetic in conjunction with an anticholinergic and a pde iv inhibitor
WO2006111960A3 (en) Methods, compositions and devices utilizing stinging cells/capsules for conditioning a tissue prior to delivery of an active agent
WO2011014003A3 (en) (+)-3-hydroxymorphinan derivatives as neuroprotectants
HK1131736A1 (en) A pharmaceutical composition having antipsychotic, antidepressant or antiepileptic activity with reduced side effect
WO2009075250A1 (en) Plant disease control agent
TW200640446A (en) Prophylactic anti-stress agent
WO2011064797A3 (en) Controlled release pharmaceutical compositions of galantamine
WO2011062936A3 (en) Self-assembled toroidal-spiral particles and manufacture and uses thereof
WO2009010298A8 (en) Paullone derivatives and its use

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 10779570

Country of ref document: EP

Kind code of ref document: A1

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 10779570

Country of ref document: EP

Kind code of ref document: A2