WO2011053247A8 - Method for the detection of an analyte by surface enhanced raman spectroscopy (sers) - Google Patents
Method for the detection of an analyte by surface enhanced raman spectroscopy (sers) Download PDFInfo
- Publication number
- WO2011053247A8 WO2011053247A8 PCT/SG2010/000383 SG2010000383W WO2011053247A8 WO 2011053247 A8 WO2011053247 A8 WO 2011053247A8 SG 2010000383 W SG2010000383 W SG 2010000383W WO 2011053247 A8 WO2011053247 A8 WO 2011053247A8
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- analyte
- enhanced raman
- surface enhanced
- sers
- biosensors
- Prior art date
Links
- 239000012491 analyte Substances 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 4
- 238000001514 detection method Methods 0.000 title abstract 2
- 238000004416 surface enhanced Raman spectroscopy Methods 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 5
- -1 heteroaryl boronic acid derivatives Chemical class 0.000 abstract 3
- 238000001069 Raman spectroscopy Methods 0.000 abstract 2
- 239000013307 optical fiber Substances 0.000 abstract 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
- 150000001543 aryl boronic acids Chemical class 0.000 abstract 1
- 239000008103 glucose Substances 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- 239000002105 nanoparticle Substances 0.000 abstract 1
- 238000004611 spectroscopical analysis Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/65—Raman scattering
- G01N21/658—Raman scattering enhancement Raman, e.g. surface plasmons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/0004—Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/025—Boronic and borinic acid compounds
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Physics & Mathematics (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Gastroenterology & Hepatology (AREA)
- Rheumatology (AREA)
- Toxicology (AREA)
- Endocrinology (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Diabetes (AREA)
- Microbiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Abstract
The present invention relates to a method for detecting an analyte, such as glucose, using Surface Enhanced Raman Spectroscopy (SERS), including contacting the analyte with one or more compounds selected from the group consisting of aryl boronic acid derivatives, heteroaryl boronic acid derivatives, aryl boronate derivatives and heteroaryl boronate derivatives attached to a metal surface that enhances Raman scattering, in particular a nanoparticle surface; and detecting a surface enhanced Raman signal from said compound. The invention further relates to new receptor compounds useful in such a method as well as biosensors including these compounds, optical fibers including such biosensors and methods of using these receptor compounds, biosensors and optical fibers for analyte detection.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SG200907194 | 2009-10-29 | ||
SG200907194-5 | 2009-10-29 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2011053247A1 WO2011053247A1 (en) | 2011-05-05 |
WO2011053247A8 true WO2011053247A8 (en) | 2011-11-03 |
Family
ID=43922356
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/SG2010/000383 WO2011053247A1 (en) | 2009-10-29 | 2010-10-08 | Method for the detection of an analyte by surface enhanced raman spectroscopy (sers) |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2011053247A1 (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103712970A (en) * | 2013-12-30 | 2014-04-09 | 青蛙王子(中国)日化有限公司 | Method for detecting content of dioxane in children cosmetics |
JP7361153B2 (en) | 2014-04-23 | 2023-10-13 | テルモ株式会社 | Non-enzymatic electrochemical sensor for measuring analytes |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102954956A (en) * | 2011-08-25 | 2013-03-06 | 福州高意光学有限公司 | Enhanced Raman spectroscopy test piece device and test piece manufacturing method |
JP5712337B2 (en) | 2012-12-27 | 2015-05-07 | パナソニック株式会社 | Method and system for detecting a test substance |
EP2767824B1 (en) | 2013-02-15 | 2019-06-26 | IMEC vzw | Method and device for detecting analytes |
RU2542427C2 (en) * | 2013-03-12 | 2015-02-20 | Федеральное государственное бюджетное учреждение науки Институт теплофизики им. С.С. Кутателадзе Сибирского отделения Российской академии наук (ИТ СО РАН) | Non-invasive laser nano-diagnostic technique for oncologic diseases |
JP5889487B2 (en) * | 2013-06-04 | 2016-03-22 | パナソニック株式会社 | Sensor chip, detection method and detection apparatus |
SG11201601656VA (en) | 2013-09-16 | 2016-04-28 | Agency Science Tech & Res | Method of detecting hydrogen peroxide |
CN105424677B (en) * | 2015-12-02 | 2018-01-12 | 公安部上海消防研究所 | Method based on SERS detection scene of fire residual organic matter |
JP6826463B2 (en) * | 2016-03-18 | 2021-02-03 | 日機装株式会社 | Component analyzer |
CN108072639A (en) * | 2016-11-10 | 2018-05-25 | 中国科学院长春光学精密机械与物理研究所 | A kind of detection method of glucose |
CN110455775B (en) * | 2019-09-11 | 2023-12-01 | 重庆大学 | Super-hydrophobic surface-enhanced substrate for surface-enhanced Raman spectrum detection |
CN114235773B (en) * | 2020-09-09 | 2024-02-09 | 南京大学 | Raman imaging method for dynamic monitoring of cell membrane repair process |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7470420B2 (en) * | 2000-12-05 | 2008-12-30 | The Regents Of The University Of California | Optical determination of glucose utilizing boronic acid adducts |
EP2161575A3 (en) * | 2004-10-29 | 2010-03-31 | The University of Akron | Analysis for glucose products using pyridinylboronic acid |
-
2010
- 2010-10-08 WO PCT/SG2010/000383 patent/WO2011053247A1/en active Application Filing
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103712970A (en) * | 2013-12-30 | 2014-04-09 | 青蛙王子(中国)日化有限公司 | Method for detecting content of dioxane in children cosmetics |
CN103712970B (en) * | 2013-12-30 | 2017-02-01 | 青蛙王子(中国)日化有限公司 | Method for detecting content of dioxane in children cosmetics |
JP7361153B2 (en) | 2014-04-23 | 2023-10-13 | テルモ株式会社 | Non-enzymatic electrochemical sensor for measuring analytes |
Also Published As
Publication number | Publication date |
---|---|
WO2011053247A1 (en) | 2011-05-05 |
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