WO2011028542A3 - Méthodes de traitement de la douleur associée à un syndrome de douleur régional complexe - Google Patents

Méthodes de traitement de la douleur associée à un syndrome de douleur régional complexe Download PDF

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Publication number
WO2011028542A3
WO2011028542A3 PCT/US2010/046523 US2010046523W WO2011028542A3 WO 2011028542 A3 WO2011028542 A3 WO 2011028542A3 US 2010046523 W US2010046523 W US 2010046523W WO 2011028542 A3 WO2011028542 A3 WO 2011028542A3
Authority
WO
WIPO (PCT)
Prior art keywords
complex regional
methods
skin surface
treating
pain associated
Prior art date
Application number
PCT/US2010/046523
Other languages
English (en)
Other versions
WO2011028542A2 (fr
Inventor
Jie Zhang
Andrew Crockett
Larry Rigby
Original Assignee
Zars Pharma, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zars Pharma, Inc. filed Critical Zars Pharma, Inc.
Publication of WO2011028542A2 publication Critical patent/WO2011028542A2/fr
Publication of WO2011028542A3 publication Critical patent/WO2011028542A3/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A61K31/245—Amino benzoic acid types, e.g. procaine, novocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)

Abstract

Cette invention concerne des méthodes de traitement de la douleur associée à un syndrome de douleur régional complexe. Plus spécifiquement, une méthode de traitement de la douleur associée à un syndrome de douleur régional complexe selon l'invention comprend l'application d'un système analgésique à une surface de la peau d'un sujet éprouvant ladite douleur et le maintien dudit système analgésique sur la surface de la peau pendant une période de temps d'au moins 30 minutes. Le système analgésique appliqué à la surface de la peau peut comprendre un composant chauffant et une formulation anesthésique locale qui contient au moins un anesthésique local. Le composant chauffant doit pouvoir chauffer la surface de la peau jusqu'à une température de 36 à 42°C.
PCT/US2010/046523 2009-08-24 2010-08-24 Méthodes de traitement de la douleur associée à un syndrome de douleur régional complexe WO2011028542A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23622109P 2009-08-24 2009-08-24
US61/236,221 2009-08-24

Publications (2)

Publication Number Publication Date
WO2011028542A2 WO2011028542A2 (fr) 2011-03-10
WO2011028542A3 true WO2011028542A3 (fr) 2011-07-21

Family

ID=43649895

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2010/046523 WO2011028542A2 (fr) 2009-08-24 2010-08-24 Méthodes de traitement de la douleur associée à un syndrome de douleur régional complexe

Country Status (1)

Country Link
WO (1) WO2011028542A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5648174B2 (ja) 2009-05-04 2015-01-07 ヌボ リサーチ インコーポレイテッド 神経腫、神経絞扼、および他の状態と関連する疼痛を処置する方法
US9186334B2 (en) 2009-05-04 2015-11-17 Nuvo Research Inc. Heat assisted lidocaine and tetracaine for transdermal analgesia

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010037104A1 (en) * 1998-09-29 2001-11-01 Jie Zhang Methods and apparatus for using controlled heat to regulate transdermal and controlled release delivery of fentanyl, other analgesics, and other medical substances
US20030012830A1 (en) * 2001-07-06 2003-01-16 Robert Small Topical compositions and methods for treating pain
US20060078600A1 (en) * 2003-02-07 2006-04-13 Lts Lohmann Therapie-Systeme Ag Transdermal therapeutic system suitable for heat application for promoting the permeation of active substances, and the use thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010037104A1 (en) * 1998-09-29 2001-11-01 Jie Zhang Methods and apparatus for using controlled heat to regulate transdermal and controlled release delivery of fentanyl, other analgesics, and other medical substances
US20030012830A1 (en) * 2001-07-06 2003-01-16 Robert Small Topical compositions and methods for treating pain
US20060078600A1 (en) * 2003-02-07 2006-04-13 Lts Lohmann Therapie-Systeme Ag Transdermal therapeutic system suitable for heat application for promoting the permeation of active substances, and the use thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
DENNIS, J. ET AL.: "Lidocaine/Tetracaine Patch", HOSPITAL PHARMACY, vol. 41, no. 3, 2006, pages 265 - 273 *

Also Published As

Publication number Publication date
WO2011028542A2 (fr) 2011-03-10

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