WO2011004345A1 - Polymorphismes de la protéine 1 de liaison amont et leur utilisation pour pronostiquer ou diagnostiquer une tension artérielle - Google Patents

Polymorphismes de la protéine 1 de liaison amont et leur utilisation pour pronostiquer ou diagnostiquer une tension artérielle Download PDF

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Publication number
WO2011004345A1
WO2011004345A1 PCT/IB2010/053146 IB2010053146W WO2011004345A1 WO 2011004345 A1 WO2011004345 A1 WO 2011004345A1 IB 2010053146 W IB2010053146 W IB 2010053146W WO 2011004345 A1 WO2011004345 A1 WO 2011004345A1
Authority
WO
WIPO (PCT)
Prior art keywords
ubpl
polymorphic
disease
gene
blood pressure
Prior art date
Application number
PCT/IB2010/053146
Other languages
English (en)
Inventor
Johan Auwerx
Rob Williams
Markku Laakso
Hana Koutnikova-Rousselin
Original Assignee
Ecole Polytechnique Federale De Lausanne (Epfl)
University Of Tennessee
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ecole Polytechnique Federale De Lausanne (Epfl), University Of Tennessee filed Critical Ecole Polytechnique Federale De Lausanne (Epfl)
Publication of WO2011004345A1 publication Critical patent/WO2011004345A1/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Abstract

La présente invention concerne des méthodes permettant d’effectuer un diagnostic et un pronostic à l'aide de variants polymorphes de l’Ubp 1 et de sondes et kits associés.
PCT/IB2010/053146 2009-07-09 2010-07-09 Polymorphismes de la protéine 1 de liaison amont et leur utilisation pour pronostiquer ou diagnostiquer une tension artérielle WO2011004345A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22409809P 2009-07-09 2009-07-09
US61/224,098 2009-07-09

Publications (1)

Publication Number Publication Date
WO2011004345A1 true WO2011004345A1 (fr) 2011-01-13

Family

ID=42829932

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2010/053146 WO2011004345A1 (fr) 2009-07-09 2010-07-09 Polymorphismes de la protéine 1 de liaison amont et leur utilisation pour pronostiquer ou diagnostiquer une tension artérielle

Country Status (1)

Country Link
WO (1) WO2011004345A1 (fr)

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4656127A (en) 1983-04-22 1987-04-07 Amersham International Plc. Method of detecting mutations in DNA and RNA
WO1991002087A1 (fr) 1989-08-11 1991-02-21 Bertin & Cie Procede rapide de detection et/ou d'identification d'une seule base sur une sequence d'acide nucleique, et ses applications
WO1992015712A1 (fr) 1991-03-05 1992-09-17 Molecular Tool, Inc. Determination d'acides nucleiques par extension de la polymerase d'oligonucleotides a l'aide de melanges terminateurs
WO1994016101A2 (fr) 1993-01-07 1994-07-21 Koester Hubert Sequençage d'adn par spectrometrie de masse
US5571676A (en) 1995-06-07 1996-11-05 Ig Laboratories, Inc. Method for mismatch-directed in vitro DNA sequencing
US5580732A (en) 1992-04-03 1996-12-03 The Perkin Elmer Corporation Method of DNA sequencing employing a mixed DNA-polymer chain probe

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4656127A (en) 1983-04-22 1987-04-07 Amersham International Plc. Method of detecting mutations in DNA and RNA
WO1991002087A1 (fr) 1989-08-11 1991-02-21 Bertin & Cie Procede rapide de detection et/ou d'identification d'une seule base sur une sequence d'acide nucleique, et ses applications
WO1992015712A1 (fr) 1991-03-05 1992-09-17 Molecular Tool, Inc. Determination d'acides nucleiques par extension de la polymerase d'oligonucleotides a l'aide de melanges terminateurs
US5580732A (en) 1992-04-03 1996-12-03 The Perkin Elmer Corporation Method of DNA sequencing employing a mixed DNA-polymer chain probe
WO1994016101A2 (fr) 1993-01-07 1994-07-21 Koester Hubert Sequençage d'adn par spectrometrie de masse
US5547835A (en) 1993-01-07 1996-08-20 Sequenom, Inc. DNA sequencing by mass spectrometry
US5571676A (en) 1995-06-07 1996-11-05 Ig Laboratories, Inc. Method for mismatch-directed in vitro DNA sequencing

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Title
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DATABASE DBsnp [online] NCBI; 24 October 2001 (2001-10-24), XP002604630, retrieved from http://www.ncbi.nlm.nih.gov/projects/SNP/snp_ref.cgi?rs=2291897 Database accession no. rs2291897 *
DATABASE DBsnp [online] NCBI; 24 October 2001 (2001-10-24), XP002604631, retrieved from http://www.ncbi.nlm.nih.gov/projects/SNP/snp_ref.cgi?rs=2272152 Database accession no. rs2272152 *
DATABASE DBsnp [online] NCBI; 28 October 2004 (2004-10-28), XP002604629, retrieved from http://www.ncbi.nlm.nih.gov/projects/SNP/snp_ref.cgi?rs=17030583 Database accession no. rs17030583 *
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