WO2011002425A3 - Pharmaceutical composition increasing solubility and stability - Google Patents

Pharmaceutical composition increasing solubility and stability Download PDF

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Publication number
WO2011002425A3
WO2011002425A3 PCT/TR2010/000126 TR2010000126W WO2011002425A3 WO 2011002425 A3 WO2011002425 A3 WO 2011002425A3 TR 2010000126 W TR2010000126 W TR 2010000126W WO 2011002425 A3 WO2011002425 A3 WO 2011002425A3
Authority
WO
WIPO (PCT)
Prior art keywords
stability
pharmaceutical composition
increasing solubility
composition increasing
solubility
Prior art date
Application number
PCT/TR2010/000126
Other languages
French (fr)
Other versions
WO2011002425A2 (en
Inventor
Bilgig Mahmut
Original Assignee
Bilgig Mahmut
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bilgig Mahmut filed Critical Bilgig Mahmut
Priority to EP10742615A priority Critical patent/EP2448575A2/en
Publication of WO2011002425A2 publication Critical patent/WO2011002425A2/en
Publication of WO2011002425A3 publication Critical patent/WO2011002425A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/549—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame having two or more nitrogen atoms in the same ring, e.g. hydrochlorothiazide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The present invention is about pharmaceutical compositions having problems of solubility and stability, the preparation method of these compositions and the medical use.
PCT/TR2010/000126 2009-07-02 2010-06-25 Pharmaceutical composition increasing solubility and stability WO2011002425A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP10742615A EP2448575A2 (en) 2009-07-02 2010-06-25 Pharmaceutical composition increasing solubility and stability

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
TR2009/05145 2009-07-02
TR200905145 2009-07-02

Publications (2)

Publication Number Publication Date
WO2011002425A2 WO2011002425A2 (en) 2011-01-06
WO2011002425A3 true WO2011002425A3 (en) 2011-03-03

Family

ID=43012669

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/TR2010/000126 WO2011002425A2 (en) 2009-07-02 2010-06-25 Pharmaceutical composition increasing solubility and stability

Country Status (2)

Country Link
EP (1) EP2448575A2 (en)
WO (1) WO2011002425A2 (en)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004096215A1 (en) * 2003-04-30 2004-11-11 Boehringer Ingelheim International Gmbh Pharmaceutical formulation of the sodium salt of telmisartan
WO2006063737A1 (en) * 2004-12-17 2006-06-22 Boehringer Ingelheim International Gmbh Combination therapy comprising telmisartan and hydrochlorothiazide
WO2007147889A2 (en) * 2006-06-23 2007-12-27 Krka, Tovarna Zdravil, D.D., Novo Mesto Preparation of telmisartan salts
US20090142398A1 (en) * 2007-11-21 2009-06-04 Pharmascience Inc. Novel pharmaceutical compositions comprising a disintegration matrix

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3025292A (en) 1962-03-13 Reduction of i
DE4225756A1 (en) 1992-01-22 1994-03-10 Thomae Gmbh Dr K Benzimidazoles, medicaments containing these compounds and process for their preparation
US5602127A (en) 1991-02-06 1997-02-11 Karl Thomae Gmbh (Alkanesultam-1-yl)-benzimidazol-1-yl)-1yl)-methyl-biphenyls useful as angiotensin-II antagonists
US5594003A (en) 1991-02-06 1997-01-14 Dr. Karl Thomae Gmbh Tetrahydroimidazo[1,2-a]pyridin-2-yl-(benzimidazol-1-yl)-methyl-biphenyls useful as angiotensin-II antagonists
US5614519A (en) 1991-02-06 1997-03-25 Karl Thomae Gmbh (1-(2,3 or 4-N-morpholinoalkyl)-imidazol-4-yl)-benizimidazol-1-yl-methyl]-biphenyls useful as angiotensin-II antagonists
SI9210098B (en) 1991-02-06 2000-06-30 Dr. Karl Thomae Benzimidazoles, drugs with this compounds, and process for their preparation
DE19901921C2 (en) 1999-01-19 2001-01-04 Boehringer Ingelheim Pharma Polymorphs of telmisartan, process for their preparation and their use in the manufacture of a medicament
DE10153737A1 (en) 2001-10-31 2003-05-28 Boehringer Ingelheim Pharma Crystalline sodium salt of telmisartan, process for its preparation and its use for the manufacture of a medicament
PT1854454E (en) 2002-01-16 2014-01-09 Boehringer Ingelheim Pharma Method for the preparation of amorphous telmisartan
DE10244681A1 (en) 2002-09-24 2004-04-08 Boehringer Ingelheim International Gmbh New solid telmisartan-containing pharmaceutical formulations and their preparation
EP1824833A2 (en) 2004-11-11 2007-08-29 LEK Pharmaceuticals D.D. Preparation of telmisartan salts with improved solubility
US20070116759A1 (en) 2005-11-22 2007-05-24 Gershon Kolatkar Pharmaceutical compositions of telmisartan

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004096215A1 (en) * 2003-04-30 2004-11-11 Boehringer Ingelheim International Gmbh Pharmaceutical formulation of the sodium salt of telmisartan
WO2006063737A1 (en) * 2004-12-17 2006-06-22 Boehringer Ingelheim International Gmbh Combination therapy comprising telmisartan and hydrochlorothiazide
WO2007147889A2 (en) * 2006-06-23 2007-12-27 Krka, Tovarna Zdravil, D.D., Novo Mesto Preparation of telmisartan salts
US20090142398A1 (en) * 2007-11-21 2009-06-04 Pharmascience Inc. Novel pharmaceutical compositions comprising a disintegration matrix

Also Published As

Publication number Publication date
WO2011002425A2 (en) 2011-01-06
EP2448575A2 (en) 2012-05-09

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