WO2011000347A1

WO2011000347A1 - Device for producing dialysis concentrate

Info

Publication number: WO2011000347A1
Application number: PCT/DE2010/000703
Authority: WO
Inventors: Manfred Pippert; Lars Breuel; Uwe Hildmann
Original assignee: Medical Support Gmbh
Priority date: 2009-07-01
Filing date: 2010-06-22
Publication date: 2011-01-06
Also published as: DE102009031473A1; DE102009031473B4

Abstract

The invention relates to a device for producing dialysis concentrate from powdery or granulated components of the dialysis concentrate or a suspension of the components, the device being characterized by a receiving container (2) for the components of the dialysis concentrate, a storage container (1) for receiving the dialysis concentrate, and a separate mixing appliance (3), which contains a line system having a pump (15), at least one filter (14), a pressure- or flow-monitoring device (21), which can detect the clogging of the at least one filter, and valves and a control and operating unit (29), the receiving container and the storage container being connected to the line system of the mixing appliance by means of connecting lines and forming a circulation circuit together with the line system of the mixing appliance. A large amount of dialysis concentrate can be produced at relatively low cost using said device.

Description

Apparatus for the production of dialysis concentrate

The invention relates to a device for the production of dialysis concentrate from solid, i. powdery or granular, components of the dialysis concentrate or a slurry of the ingredients in water or a solution.

From DE 1 99 31 077 A1, such a device is known, can be produced with the dialysis concentrate for a dialysis treatment. For this purpose, a cartridge is inserted into a circulation circuit and a slurry of the constituents of the dialysis concentrate in the cartridge as long as traversed by water until all components are dissolved. In addition, a batch vessel is included in the circulation circuit which receives the dialysis concentrate thus formed. The components of the device are housed in a housing, wherein the device is connectable as an additional device with a dialysis machine. This device is only suitable for producing a small amount of dialysis concentrate.

The present invention has for its object to provide a device with which a large amount of dialysis concentrate can be produced at relatively low cost.

This object is achieved by the features of claim 1. Advantageous embodiments of the invention are characterized in the subclaims. The invention provides that a receptacle for the constituents of the dialysis concentrate and a storage container for receiving the finished dialysis concentrate are connected via connecting lines to a separate mixing device, which is a line system with a pump, at least one filter, a pressure or flow monitoring device, the clogging the at least one filter can recognize, and contains valves and a control and operating unit. The receptacle and the storage container are arranged in a circulation circuit. The receptacle may be hermetically sealed by a lid. Alternatively, a second pump may be provided for evacuating the liquid from the receptacle, or the receptacle is positioned so high that the transport is by gravity.

The receptacle contains, for example, 220 liters slurried components of the dialysis concentrate in a barrel, while in this case the storage container can hold about 1, 000 liters of finished dialysis concentrate. Of course, smaller or larger amounts of dialysis concentrate can be produced with the device according to the invention.

The line system of the mixer designed as a separate device is connected to a pure water or RO water inlet. The pure water introduced into the line system is introduced by a pump of the mixing device via a connection line connected to the line system in the bottom portion of the receptacle, wherein solid or granular constituents of the dialysis concentrate are fluidized. The flow is fed into the receptacle in such a way that the solid or granular constituents pass into solution. The water with the optionally powdered or granular components (as long as they are still present in the outlet of the receptacle) is conveyed by the pressure in the receptacle in at least one filter. In this at least one filter, the solid components are completely dissolved because the membrane of the filter does not allow any solid particles to pass. The filter is connected via the conduit system of the mixer and a connecting hose attached to the mixing device with the storage tank, in the upper end of the water with dissolved constituents of the dialysis concentrate is introduced.

From the bottom of the storage tank, another connection hose leads back to the mixing device, where this connection hose is connected to the line system of the mixing device, namely with the wiring harness, through which the pure water is pumped to the receiving container.

In the flow direction before the at least one filter is a pressure sensor which monitors the pressure in the line leading to the filter. If this pressure increases significantly, this is due to a significant loading of the filter with solids which inhibit the passage of the fluid through the membrane. So that the filter can not clog in this way, with the result that it is no longer or insufficiently flowed through by liquid, the pressure sensor is connected to the control unit of the mixer, which then reduces the performance of the feeding pump to the receptacle, so less Solids are swirled in the receptacle to the head area and thus be promoted by the connecting hose only a few (or temporarily no) powdered or granular constituents of the dialysis concentrate to the filter.

The design can also be made such that a line leading from the line section leading to the feeding connection hose of the receiving container branches off, leading to the at least one filter, so that pure water can be supplied directly to the filter. The piping system of the mixing device contains the corresponding valves, which are actuated by the operating and control unit. Preferably, two filters are connected in parallel arrangement in the line system of the mixer.

Thus, only water with completely dissolved components of the dialysis concentrate, without any solids that would otherwise accumulate at the bottom of the storage tank, enters the storage tank. For this reason, as a storage tank, a conventional container or container can be used, which is inexpensive available on the market. The storage container may have a cubic or cylindrical shape (without the invention being limited thereto) and its bottom may be completely flat, since there can not deposit solid substances which would have to be conveyed back into the circulation circuit. At the top and bottom of the storage tank are connections for the lines leading to the mixer, which are preferably formed by flexible hoses, as is the case with the connection lines of the receptacle.

The storage tank can also be provided with an inliner, which can be replaced regularly for hygienic reasons. Similarly, the low-cost storage tank can be discarded when contaminated.

Further, the invention provides that for the four connection hoses of the mixing device connecting elements are provided on or in the device to which the ends of the two connection hoses of the receptacle and the storage container can be connected, so that the hoses are included in a closed recirculation of the mixer. This allows the entire line system of the mixer with the four connecting hoses flushed with little effort and optionally disinfected. For this purpose, the line system of the mixing device is provided with a drain. In addition, located in the inflow region from the storage tank, a sampling line of the liquid flowing through. The mixer operates in the manner described above until all solid components of the dialysis concentrate are dissolved in a predetermined amount of water and homogenized. The storage tank can then supply a loop or be used for canister filling.

The device according to the invention has the advantage of low cost of the storage tank, the absence of a separate approach tank, low installation costs, and it provides security of mixing by assigning the storage container to an associated receptacle by the mixer may be provided with a bar code system. The mixer allows for its low volumes of media-carrying components excellent cleaning and disinfection at low cost.

It may also be provided that the storage tank is permanently installed and that the finished dialysis concentrate is e.g. is filled into small containers, including a 3-way valve can be provided in the leading away from the ground line. It can also be provided two or more storage containers and optionally connectable to the mixing device.

As mentioned above, the device can also be used for mixing small amounts of concentrate.

Further details of the invention will become apparent from the following description of preferred embodiments. Showing:

Figure 1 shows a device with a storage tank;

Figure 2 shows a device with two storage tanks and

Figure 3, the cleaning concept of the mixing device.

Figure 1 shows a device with a mobile combination of a storage tank 1 and a receptacle 2 to a mixing device 3. The storage tank 1 is connected via a leading away from its bottom connecting hose 4 and a returning connection hose 5, which opens at the top of the storage tank 1, connected to the conduit system of the mixing device 3. In the supplying wiring harness opens a RO-water inlet 6 with a water meter 7 and a valve 8 a. Downstream of a sampling line 9 branches off with a valve 10. Downstream of another valve 1 1 is a branching line 12, which leads via a valve to the inlet of two filters 14.

Downstream of the branch is a pump 1 5 in a line section 1 6, which leads to a connection hose 17 which leads with a pipe section 18 to the bottom portion of the receiving container 2, in which the solid or slurried components of the dialysis concentrate.

From the upper region of the receiving container 2, a connection hose 19 leads to a line section 20 of the line system of the mixing device 3, with which a pressure sensor 21 is in communication and a check valve 22 follows. The line section 20 is connected to the left-hand filter in the figure.

From the wiring harness 16 branches off a wiring harness 23, which leads via a valve 24 to the other filter 14. The outputs 24 and 26 of the two filters 14 open into one another and are behind a valve 27 with the connection hose 5 in connection.

Downstream of the pump 1 5 there is a drain 28. An operating / control unit of the mixing device 3 is identified by the reference numeral 29. Further features of the mixing device 3 can be seen from the schematic figure 1.

The device according to FIG. 2 differs from that of FIG. 1 in that two storage tanks 1 are permanently installed. In the leading from the bottom of the two storage tanks 1 lines is in each case a 3-way Valve 30, can be filled via the dialysis concentrate, for example, in smaller containers or can be guided via existing loop lines to the consumer.

In addition, the mixing device includes a compressor 32, a surge tank 33 and a compressed air line system with which for emptying the receiving container 2 compressed air via a pneumatic valve 34 and a check valve 35 via the hose 19 into the receptacle 2 can be inserted so that the contents of the receptacle completely flows through the tube 17 in the piping system of the mixer. Alternatively, the receptacle could be emptied by reversing the pump 1 5.

FIG. 3 shows that two U-shaped connections 31 for the ends of the hoses 4, 5, 17 and 19, by means of which the ends can be connected to one another, are attached to the mixing device 3. This results in a closed circulation line, which makes it possible that the mixing device 3 can be flushed with its connection hoses with pure water and optionally disinfected, for which only a small amount of water / disinfection amount is required.

It is emphasized that the invention is not limited to the described and illustrated embodiments. Rather, all disclosed features can be individually combined with each other in any meaningful way.

Claims

claims

1 . Device for producing dialysis concentrate from powdered or granular constituents of the dialysis concentrate or a slurry of the constituents,

marked by

a receptacle (2) for the components of the dialysis concentrate, a storage container (1) for receiving the dialysis concentrate and a separate mixing device (3) having a line system with a pump

(15), at least one filter (14), a pressure or flow monitoring device, which can detect the clogging of the at least one filter, and valves and a control and operating unit (29), wherein the receptacle (2) and the Storage container (1) through

Connection pipes (4,5; 17, 19) with the piping system of the mixer

(3) are connected and together with the management system of the

Mixing device (3) form a circulation circuit.

2. Apparatus according to claim 1,

characterized,

the lines (4, 5, 17, 19) connecting the receiving container (2) and the storage container (1) to the line system of the mixing device (3) are formed by flexible tubes.

3. Apparatus according to claim 1 or 2,

characterized,

that the conduit system of the mixing device (3) has a pure water inlet (6).

4. Apparatus according to claim 3,

characterized, in that the line section of the line system of the mixing device (3) connected to the clean water inlet (6) is connected to a connecting line (17) which ends in the bottom area of the receiving container (2).

5. Device according to one of claims 1 to 4,

characterized,

the other connecting line (19) of the receiving container (2) ends in the upper region of the receiving container (2).

6. Device according to one of claims 1 to 5,

characterized,

a connecting line (5) of the storage tank (1) is connected at the upper end region and the other connecting line (4) is connected at the bottom region.

7. Device according to one of claims 1 to 6,

characterized,

in that the at least one filter (14) is switched on in the line section leading from the upper end of the receptacle (2) to the upper end of the storage container (1).

8. Device according to one of claims 1 to 7,

characterized,

that two filters (14) are connected in parallel in the piping system of the mixing device (3).

9. Device according to one of claims 1 to 8,

characterized,

the pressure or flow monitoring device is a pressure gauge (21).

10. Device according to one of claims 1 to 9,

characterized,

in that the mixing device (3) has connections (31) with which the ends of the two lines (17, 19, 4.5) of the receiving container (2) and of the storage container (1) can be connected to each other.

1 1. Device according to one of claims 1 to 10,

characterized,

in that the line system of the mixing device (3) is connected to a discharge line (28).

12. Device according to one of claims 1 to 1 1,

characterized,

the piping system of the mixing device (3) is connected to a sampling line (9).

13. Device according to one of claims 1 to 12,

characterized,

that the line system of the mixing device (3) allows a flushing of the filter with ultrapure water.

14. Device according to one of claims 1 to 13,

characterized,

that a system cleaning, system disinfection due to the small volumes of the mixer is easy to implement.